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認知障害における脳-末梢連関性成長因子発現のアンバランス:その評価と制御法の開発
Tabuchi, A. (Principal Investigator)
Japan Society for the Promotion of Science
2025/06/27 → 2027/03/31
Project: Research Project
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老化線維芽細胞制御によるがん休眠細胞の封じ込めによる骨転移治療法の開発
Hayakawa, Y. (Principal Investigator)
Japan Society for the Promotion of Science
2025/06/27 → 2027/03/31
Project: Research Project
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核内受容体とMRTFによる相乗的記憶改善を狙った脳の新規ニュートラシューティカルズ
Ihara, D. (Principal Investigator) & Tabuchi, A. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2025/04/01 → 2028/03/31
Project: Research Project
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血管内皮障害と脈管増生因子に基づくフォンタン術後リンパ系合併症の病態解明
Ibuki, K. (Principal Investigator), Taguchi, M. (Co-Investigator(Kenkyū-buntansha)), Nakaoka, H. (Co-Investigator(Kenkyū-buntansha)), Ozawa, S. (Co-Investigator(Kenkyū-buntansha)), Hirono, K. (Co-Investigator(Kenkyū-buntansha)) & Imamura, T. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2025/04/01 → 2028/03/31
Project: Research Project
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Development of a novel treatment based on the circadian rhythm unique to atopic dermatitis
To, H. (Principal Investigator)
Japan Society for the Promotion of Science
2025/04/01 → 2028/03/31
Project: Research Project
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mRNAキャップ特異的m6Amメチル化酵素PCIF1による遺伝子発現制御機構の解明
Hirose, Y. (Principal Investigator) & Tanaka, A. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2025/04/01 → 2028/03/31
Project: Research Project
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膜イオンチャンネルに着目したCTCクラスター化阻害分子機構解明による胃癌治療戦略
Hashimoto, I. (Principal Investigator), Okumura, T. (Co-Investigator(Kenkyū-buntansha)), Fujii, T. (Co-Investigator(Kenkyū-buntansha)), Sakai, H. (Co-Investigator(Kenkyū-buntansha)) & Fujii, T. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2025/04/01 → 2028/03/31
Project: Research Project
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Elucidation of the mechanisms underlying comorbidity of alcohol use disorder in bipolar disorder
Yano, Y. (Principal Investigator)
Japan Society for the Promotion of Science
2025/04/01 → 2028/03/31
Project: Research Project
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PD-1+/CD8+T細胞の日周リズムを利用した時間免疫療法の構築
Seto, Y. (Principal Investigator)
Japan Society for the Promotion of Science
2025/04/01 → 2028/03/31
Project: Research Project
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分子シミュレーションとAIによる肺がん分子標的薬の薬効予測法の確立
Sugano, A. (Principal Investigator), Takaoka, Y. (Co-Investigator(Kenkyū-buntansha)) & 赤間啓之 (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2025/04/01 → 2028/03/31
Project: Research Project
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新しい高原子価ビスマス触媒の創成とフェノール酸化を起点とする有機合成への展開
Kasama, K. (Principal Investigator)
Japan Society for the Promotion of Science
2025/04/01 → 2027/03/31
Project: Research Project
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大腸粘膜固有層のT細胞非依存的IgA産生誘導におけるTRAF5の制御機構の解明
Kuniishi, M. (Principal Investigator), So, T. (Co-Investigator(Kenkyū-buntansha)) & Morita, M. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2025/04/01 → 2028/03/31
Project: Research Project
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Development of Epimedium plant resources based on elucidation of genetic diversity
Lee, J. (Principal Investigator) & Yamamura, Y. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2025/04/01 → 2029/03/31
Project: Research Project
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Elucidation of the exhaustion process of NK cells in tumor
Hayakawa, Y. (Principal Investigator) & 山口哲志 (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2025/04/01 → 2028/03/31
Project: Research Project
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アルツハイマー病「未病期」バイオマーカーの同定と発症・進行機構の解明
Kume, T. (Principal Investigator), Uta, D. (Co-Investigator(Kenkyū-buntansha)) & Sawahata, M. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2025/04/01 → 2028/03/31
Project: Research Project
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神経軸索伸長活性アルカロイドの創出を指向したアルカロイド生合成酵素の機能改変
Morita, H. (Principal Investigator) & Nakashima, Y. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2025/04/01 → 2028/03/31
Project: Research Project
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薬用ジテルペンの合理的生産プラットホームの構築を目指した多彩な代謝機構の解明
Yamamura, Y. (Principal Investigator) & Lee, J. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2025/04/01 → 2028/03/31
Project: Research Project
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脳内概日リズムに同調させた経鼻脳薬物送達法による神経炎症治療薬の開発
Inoue, D. (Principal Investigator)
Japan Society for the Promotion of Science
2025/04/01 → 2028/03/31
Project: Research Project
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Development of OX40 Agonists and Their Application in T Cell Immunotherapy
So, T. (Principal Investigator), Morita, M. (Co-Investigator(Kenkyū-buntansha)) & Kuniishi, M. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2025/04/01 → 2028/03/31
Project: Research Project
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幹細胞性および細胞遊走における非定型的活性型EphA2の役割
Zhou, Y. (Principal Investigator)
Japan Society for the Promotion of Science
2025/04/01 → 2028/03/31
Project: Research Project
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ABCD1機能欠損リンパ球のTh1型反応の亢進が大脳型ALD発症に関与する
Morita, M. (Principal Investigator), So, T. (Co-Investigator(Kenkyū-buntansha)) & Kuniishi, M. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2025/04/01 → 2028/03/31
Project: Research Project
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化学物質によるグリア活性化を介した新たな神経毒性機序の解明とバイオマーカーの同定
Hirano, T. (Principal Investigator), 星信彦 (Co-Investigator(Kenkyū-buntansha)) & 池中良徳 (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2025/04/01 → 2028/03/31
Project: Research Project
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Multifaceted regulators of fatty acid metabolism in the control of metabolic liver disease.
Nakagawa, Y. (Principal Investigator)
Japan Society for the Promotion of Science
2025/04/01 → 2028/03/31
Project: Research Project
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Analysis of Manic Switch Mechanism by Antidepressants in Bipolar Disorder model mice
Yano, Y. (Principal Investigator)
Japan Society for the Promotion of Science
2024/07/31 → 2026/03/31
Project: Research Project
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Neural basis mechanism underlying self-value transformation and long-term consolidation through altruistic behavior
Yokose, J. (Principal Investigator)
Japan Society for the Promotion of Science
2024/07/31 → 2026/03/31
Project: Research Project
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グリアーニューロン連関の撹乱から迫る化学物質による神経毒性の上流メカニズムの探索
Hirano, T. (Principal Investigator), 星信彦 (Co-Investigator(Kenkyū-buntansha)) & 池中良徳 (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2024/06/28 → 2026/03/31
Project: Research Project
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腫瘍-神経クロストークに着目した食道癌転移機構の解明
Okumura, T. (Principal Investigator), Terabayashi, K. (Co-Investigator(Kenkyū-buntansha)), Fujii, T. (Co-Investigator(Kenkyū-buntansha)) & Fujii, T. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2024/04/01 → 2027/03/31
Project: Research Project
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Elucidation of the pathogenic mechanism of HLA-related drug hypersensitivity focusing on the intracellular energy metabolism environment of immune cells
Susukida, T. (Principal Investigator)
Japan Society for the Promotion of Science
2024/04/01 → 2027/03/31
Project: Research Project
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FIHを標的とした代謝異常関連脂肪肝MAFLDの治療に有効なシード化合物の探索
Nakashima, Y. (Principal Investigator)
Japan Society for the Promotion of Science
2024/04/01 → 2026/03/31
Project: Research Project
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脂肪酸が腸管幹細胞の分化・自己複製を活性化するシグナル伝達を制御する機序の解明
Araki, M. (Principal Investigator)
Japan Society for the Promotion of Science
2024/04/01 → 2026/03/31
Project: Research Project
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SOX10 regulates melanoma heterogeneity
Yokoyama, S. (Principal Investigator), Hayakawa, Y. (Co-Investigator(Kenkyū-buntansha)) & Hayashi, R. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2024/04/01 → 2027/03/31
Project: Research Project
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Mechanistic elucidation of the preventive effect of pig-derived bile acids on life-related diseases through the improvement of gut barrier impairment
Watanabe, S. (Principal Investigator), 古澤之裕 (Co-Investigator(Kenkyū-buntansha)) & Tabuchi, Y. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2024/04/01 → 2027/03/31
Project: Research Project
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Development of cyclodextrin-inclusive functional molecules that exhibit unique luminescent properties and catalytic activity
Ohishi, Y. (Principal Investigator)
Japan Society for the Promotion of Science
2024/04/01 → 2027/03/31
Project: Research Project
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Molecular and structural basis of natural moisturizing factor production mechanisms by profilaggrin-degrading enzymes.
Obita, T. (Principal Investigator)
Japan Society for the Promotion of Science
2024/04/01 → 2027/03/31
Project: Research Project
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中性子解析に基づく分子標的薬の選択性向上と治療薬開発
Yokoyama, T. (Principal Investigator) & Okada, T. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2024/04/01 → 2027/03/31
Project: Research Project
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生体環境での光治療を志向した近赤外光レドックス触媒の開発研究
Tanioka, M. (Principal Investigator)
Japan Society for the Promotion of Science
2024/04/01 → 2027/03/31
Project: Research Project
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変異酵素の立体構造を化学的に操作できるシャペロン化合物の合理的設計と機能解析
Kato, A. (Principal Investigator), 石井達 (Co-Investigator(Kenkyū-buntansha)), 中込泉 (Co-Investigator(Kenkyū-buntansha)) & 名取良浩 (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2024/04/01 → 2027/03/31
Project: Research Project
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PRMT1の標的基質の網羅的探索から紐解く還元ストレスと心機能障害に至る分子機構
Kim, J. (Principal Investigator)
Japan Society for the Promotion of Science
2024/04/01 → 2027/03/31
Project: Research Project
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2波長連続光変換反応を利用したベンズアゼチンの創出と含窒素縮環骨格合成への応用
Matsuya, Y. (Principal Investigator) & Tanioka, M. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2024/04/01 → 2027/03/31
Project: Research Project
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シングルセル技術による植物代謝システムの時空間的ダイナミズムの解明
Shoji, T. (Principal Investigator) & 森哲哉 (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2024/04/01 → 2028/03/31
Project: Research Project
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脂肪組織の可塑性メモリーを規定するエピゲノム制御による肥満リバウンド抑止法の開発
Wada, T. (Principal Investigator), Sasaoka, T. (Co-Investigator(Kenkyū-buntansha)), Tsuneki, H. (Co-Investigator(Kenkyū-buntansha)) & Onogi, Y. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2024/04/01 → 2028/03/31
Project: Research Project
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Structure Control of Meso-Hierarchical Materials Triggered by Saccharide Recognition
Ohishi, Y. (Principal Investigator)
Japan Society for the Promotion of Science
2024/04/01 → 2026/03/31
Project: Public
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サルコペニアや生活不活発病による認知症発症を予防する抗ヘモペキシン戦略
Tohda, C. (Principal Investigator)
Japan Society for the Promotion of Science
2023/06/30 → 2026/03/31
Project: Research Project
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血液脳関門ABC排出輸送体制御による多形性膠芽腫への薬物送達戦略構築と有望性実証
Tega, Y. (Principal Investigator)
Japan Society for the Promotion of Science
2023/04/01 → 2026/03/31
Project: Research Project
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ニューロセンサー型転写因子の機能理解と同調制御による革新的記憶改善法の開発
Tabuchi, A. (Principal Investigator) & Ihara, D. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2023/04/01 → 2026/03/31
Project: Research Project
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Investigation on naphthylisoquinoline alkaloids as potential antiausterity chemotherapy for pancreatic cancer
Awale, S. (Principal Investigator) & Fujii, T. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2023/04/01 → 2028/03/31
Project: Research Project
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Development of a novel treatment for diabetes and depression by promoting olfactory and orexin system
Sasaoka, T. (Principal Investigator), Tsuneki, H. (Co-Investigator(Kenkyū-buntansha)) & Wada, T. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2023/04/01 → 2026/03/31
Project: Research Project
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人工的なPS露出によるeat-meシグナルは免疫チェックポイントを上回るか
Nakao, H. (Principal Investigator)
Japan Society for the Promotion of Science
2023/04/01 → 2026/03/31
Project: Research Project