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ABCD1機能欠損リンパ球のTh1型反応の亢進が大脳型ALD発症に関与する
Morita, M. (Principal Investigator)
Japan Society for the Promotion of Science
2025/04/01 → 2028/03/31
Project: Research Project
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アトピー性皮膚炎固有の概日リズムを基盤とした新規治療法の開発
To, H. (Principal Investigator)
Japan Society for the Promotion of Science
2025/04/01 → 2028/03/31
Project: Research Project
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脳内概日リズムに同調させた経鼻脳薬物送達法による神経炎症治療薬の開発
Inoue, D. (Principal Investigator)
Japan Society for the Promotion of Science
2025/04/01 → 2028/03/31
Project: Research Project
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OX40アゴニストの創製から T 細胞免疫療法への展開
So, T. (Principal Investigator)
Japan Society for the Promotion of Science
2025/04/01 → 2028/03/31
Project: Research Project
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幹細胞性および細胞遊走における非定型的活性型EphA2の役割
Zhou, Y. (Principal Investigator)
Japan Society for the Promotion of Science
2025/04/01 → 2028/03/31
Project: Research Project
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遺伝的多様性の解明に基づいたイカリソウ属植物資源の開拓
Lee, J. (Principal Investigator)
Japan Society for the Promotion of Science
2025/04/01 → 2029/03/31
Project: Research Project
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薬用ジテルペンの合理的生産プラットホームの構築を目指した多彩な代謝機構の解明
Yamamura, Y. (Principal Investigator)
Japan Society for the Promotion of Science
2025/04/01 → 2028/03/31
Project: Research Project
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NK細胞の腫瘍組織内での疲弊プロセスの解明
Hayakawa, Y. (Principal Investigator)
Japan Society for the Promotion of Science
2025/04/01 → 2028/03/31
Project: Research Project
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アルツハイマー病「未病期」バイオマーカーの同定と発症・進行機構の解明
Kume, T. (Principal Investigator)
Japan Society for the Promotion of Science
2025/04/01 → 2028/03/31
Project: Research Project
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多面的な脂肪酸代謝制御因子による代謝性肝疾患制御の解明
Nakagawa, Y. (Principal Investigator)
Japan Society for the Promotion of Science
2025/04/01 → 2028/03/31
Project: Research Project
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化学物質によるグリア活性化を介した新たな神経毒性機序の解明とバイオマーカーの同定
Hirano, T. (Principal Investigator)
Japan Society for the Promotion of Science
2025/04/01 → 2028/03/31
Project: Research Project
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神経軸索伸長活性アルカロイドの創出を指向したアルカロイド生合成酵素の機能改変
Morita, H. (Principal Investigator)
Japan Society for the Promotion of Science
2025/04/01 → 2028/03/31
Project: Research Project
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新しい高原子価ビスマス触媒の創成とフェノール酸化を起点とする有機合成への展開
Kasama, K. (Principal Investigator)
Japan Society for the Promotion of Science
2025/04/01 → 2027/03/31
Project: Research Project
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分子シミュレーションとAIによる肺がん分子標的薬の薬効予測法の確立
Sugano, A. (Principal Investigator)
Japan Society for the Promotion of Science
2025/04/01 → 2028/03/31
Project: Research Project
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双極性障害におけるアルコール使用障害併発メカニズムの究明
Yano, Y. (Principal Investigator)
Japan Society for the Promotion of Science
2025/04/01 → 2028/03/31
Project: Research Project
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PD-1+/CD8+T細胞の日周リズムを利用した時間免疫療法の構築
Seto, Y. (Principal Investigator)
Japan Society for the Promotion of Science
2025/04/01 → 2028/03/31
Project: Research Project
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核内受容体とMRTFによる相乗的記憶改善を狙った脳の新規ニュートラシューティカルズ
Ihara, D. (Principal Investigator)
Japan Society for the Promotion of Science
2025/04/01 → 2028/03/31
Project: Research Project
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Neural basis mechanism underlying self-value transformation and long-term consolidation through altruistic behavior
Yokose, J. (Principal Investigator)
Japan Society for the Promotion of Science
2024/07/31 → 2026/03/31
Project: Research Project
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Analysis of Manic Switch Mechanism by Antidepressants in Bipolar Disorder model mice
Yano, Y. (Principal Investigator)
Japan Society for the Promotion of Science
2024/07/31 → 2026/03/31
Project: Research Project
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グリアーニューロン連関の撹乱から迫る化学物質による神経毒性の上流メカニズムの探索
Hirano, T. (Principal Investigator), 信彦星 (Co-Investigator(Kenkyū-buntansha)) & 良徳池中 (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2024/06/28 → 2026/03/31
Project: Research Project
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脂肪酸が腸管幹細胞の分化・自己複製を活性化するシグナル伝達を制御する機序の解明
Araki, M. (Principal Investigator)
Japan Society for the Promotion of Science
2024/04/01 → 2026/03/31
Project: Research Project
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Elucidation of the pathogenic mechanism of HLA-related drug hypersensitivity focusing on the intracellular energy metabolism environment of immune cells
Susukida, T. (Principal Investigator)
Japan Society for the Promotion of Science
2024/04/01 → 2027/03/31
Project: Research Project
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FIHを標的とした代謝異常関連脂肪肝MAFLDの治療に有効なシード化合物の探索
Nakashima, Y. (Principal Investigator)
Japan Society for the Promotion of Science
2024/04/01 → 2026/03/31
Project: Research Project
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Mechanistic elucidation of the preventive effect of pig-derived bile acids on life-related diseases through the improvement of gut barrier impairment
Watanabe, S. (Principal Investigator), 之裕古澤 (Co-Investigator(Kenkyū-buntansha)) & Tabuchi, Y. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2024/04/01 → 2027/03/31
Project: Research Project
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腫瘍-神経クロストークに着目した食道癌転移機構の解明
Okumura, T. (Principal Investigator), Terabayashi, K. (Co-Investigator(Kenkyū-buntansha)), Fujii, T. (Co-Investigator(Kenkyū-buntansha)) & Fujii, T. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2024/04/01 → 2027/03/31
Project: Research Project
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SOX10 regulates melanoma heterogeneity
Yokoyama, S. (Principal Investigator), Hayakawa, Y. (Co-Investigator(Kenkyū-buntansha)) & Hayashi, R. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2024/04/01 → 2027/03/31
Project: Research Project
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生体環境での光治療を志向した近赤外光レドックス触媒の開発研究
Tanioka, M. (Principal Investigator)
Japan Society for the Promotion of Science
2024/04/01 → 2027/03/31
Project: Research Project
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中性子解析に基づく分子標的薬の選択性向上と治療薬開発
Yokoyama, T. (Principal Investigator) & Okada, T. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2024/04/01 → 2027/03/31
Project: Research Project
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Molecular and structural basis of natural moisturizing factor production mechanisms by profilaggrin-degrading enzymes.
Obita, T. (Principal Investigator)
Japan Society for the Promotion of Science
2024/04/01 → 2027/03/31
Project: Research Project
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2波長連続光変換反応を利用したベンズアゼチンの創出と含窒素縮環骨格合成への応用
Matsuya, Y. (Principal Investigator) & Tanioka, M. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2024/04/01 → 2027/03/31
Project: Research Project
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Dosage regimen for receptor antagonists based on longitudinal mathematical model considering patients' growth and disease risk
Taguchi, M. (Principal Investigator), Yoshida, T. (Co-Investigator(Kenkyū-buntansha)), Hirono, K. (Co-Investigator(Kenkyū-buntansha)) & Hara, A. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2024/04/01 → 2027/03/31
Project: Research Project
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PRMT1の標的基質の網羅的探索から紐解く還元ストレスと心機能障害に至る分子機構
Kim, J. (Principal Investigator)
Japan Society for the Promotion of Science
2024/04/01 → 2027/03/31
Project: Research Project
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変異酵素の立体構造を化学的に操作できるシャペロン化合物の合理的設計と機能解析
Kato, A. (Principal Investigator), 達石井 (Co-Investigator(Kenkyū-buntansha)), 泉中込 (Co-Investigator(Kenkyū-buntansha)) & 良浩名取 (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2024/04/01 → 2027/03/31
Project: Research Project
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脂肪組織の可塑性メモリーを規定するエピゲノム制御による肥満リバウンド抑止法の開発
Wada, T. (Principal Investigator), Sasaoka, T. (Co-Investigator(Kenkyū-buntansha)), Tsuneki, H. (Co-Investigator(Kenkyū-buntansha)) & Onogi, Y. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2024/04/01 → 2028/03/31
Project: Research Project
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シングルセル技術による植物代謝システムの時空間的ダイナミズムの解明
Shoji, T. (Principal Investigator) & 森哲哉 (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2024/04/01 → 2028/03/31
Project: Research Project
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Structure Control of Meso-Hierarchical Materials Triggered by Saccharide Recognition
Ohishi, Y. (Principal Investigator)
Japan Society for the Promotion of Science
2024/04/01 → 2026/03/31
Project: Public
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アルツハイマー病の根本的治療戦略の確立:神経回路の“正確な修復”からのアプローチ
Yang, X. (Principal Investigator)
Japan Society for the Promotion of Science
2024/04/01 → 2027/03/31
Project: Research Project
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Development of cyclodextrin-inclusive functional molecules that exhibit unique luminescent properties and catalytic activity
Ohishi, Y. (Principal Investigator)
Japan Society for the Promotion of Science
2024/04/01 → 2027/03/31
Project: Research Project
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サルコペニアや生活不活発病による認知症発症を予防する抗ヘモペキシン戦略
Tohda, C. (Principal Investigator)
Japan Society for the Promotion of Science
2023/06/30 → 2026/03/31
Project: Research Project
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血液脳関門ABC排出輸送体制御による多形性膠芽腫への薬物送達戦略構築と有望性実証
Tega, Y. (Principal Investigator)
Japan Society for the Promotion of Science
2023/04/01 → 2026/03/31
Project: Research Project
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脂質二重膜透過アッセイ系と人工知能による膜透過性環状ペプチドの合理的設計
Ikeda, K. (Principal Investigator), Nakao, H. (Co-Investigator(Kenkyū-buntansha)) & 倫史亀田 (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2023/04/01 → 2027/03/31
Project: Research Project
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Investigation on naphthylisoquinoline alkaloids as potential antiausterity chemotherapy for pancreatic cancer
Awale, S. (Principal Investigator) & Fujii, T. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2023/04/01 → 2028/03/31
Project: Research Project
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人工的なPS露出によるeat-meシグナルは免疫チェックポイントを上回るか
Nakao, H. (Principal Investigator)
Japan Society for the Promotion of Science
2023/04/01 → 2026/03/31
Project: Research Project
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Ultrasound mechanosensing: elucidation of the role of piezo1 on its regulation of cellular function
Tabuchi, Y. (Principal Investigator), Hasegawa, H. (Co-Investigator(Kenkyū-buntansha)), 鈴木信雄 (Co-Investigator(Kenkyū-buntansha)), 之裕古澤 (Co-Investigator(Kenkyū-buntansha)) & 鈴木信雄,古澤之裕,田渕圭章,関あずさ,高垣裕子,染井正徳,江尻貞一,池亀美華,黒田康平,関口俊男,松原 創,高橋昭久,平山 順,服部淳彦. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2023/04/01 → 2026/03/31
Project: Research Project
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Pathophysiology of pulmonary hypertension focusing on the dysfunction of a novel potassium Pump
Fujii, T. (Principal Investigator)
Japan Society for the Promotion of Science
2023/04/01 → 2026/03/31
Project: Research Project
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転移性骨腫瘍に対する積極的治療法の開発
Sasaki, S. (Principal Investigator)
Japan Society for the Promotion of Science
2023/04/01 → 2026/03/31
Project: Research Project
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ニューロセンサー型転写因子の機能理解と同調制御による革新的記憶改善法の開発
Tabuchi, A. (Principal Investigator) & Ihara, D. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2023/04/01 → 2026/03/31
Project: Research Project
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脳クレアチン供給を実現するモノカルボン酸輸送体認識型プロドラッグ開発とその有用性
Hosoya, K.-I. (Principal Investigator), 正憲立川 (Co-Investigator(Kenkyū-buntansha)), Toyooka, N. (Co-Investigator(Kenkyū-buntansha)) & Akanuma, S.-I. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2023/04/01 → 2026/03/31
Project: Research Project
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行動薬理学的手法によるアパシー病態の新規評価系構築と分子基盤の解明
Sawahata, M. (Principal Investigator)
Japan Society for the Promotion of Science
2023/04/01 → 2026/03/31
Project: Research Project
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Development of a novel treatment for diabetes and depression by promoting olfactory and orexin system
Sasaoka, T. (Principal Investigator), Tsuneki, H. (Co-Investigator(Kenkyū-buntansha)) & Wada, T. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2023/04/01 → 2026/03/31
Project: Research Project