Hideto To

h-index

Research activity per year

Campus career

薬学科　教授　2011/01/16-2019/09/30
東西統合医学系　教授　2011/01/16-2019/09/30
薬学・和漢系　教授　2019/10/01-
薬学科　教授　2019/10/01-
薬学部薬学科　基幹教員
学部運営への参画状況・・・有-教授会
担当授業科目に係る状況・・・主要授業科目担当

Affiliated academic society

日本薬学会　所属期間：1996/02-
日本臨床薬理学会　所属期間：2002/11-
日本TDM学会　所属期間：2004/05-
日本医療薬学会　所属期間：2004/08-
日本リウマチ学会　所属期間：2005/09-
日本薬剤学会　所属期間：2007/02-
日本時間生物学会　所属期間：2007/04-
日本臨床腫瘍学会　所属期間：2007/08-
日本癌学会　所属期間：2009/07-
日本薬理学会　所属期間：2010/09-
富山県薬剤師会　所属期間：2011/02-
和漢医薬学会　所属期間：2013/08-

Research interests

今ある薬の“眠っているポテンシャル"を呼び覚ますための新たな治療法の提案をコンセプトに研究活動を行っています.
これらを解決する方法として,主に“生体リズム"に着目しています.生体機能の様々な周期性はヒトを始めとする多くの生物で存在します.特に,概日リズムは疾患や病状にも存在し,一日の中で発作など発症しやすい時間帯が知られています. そこで,“投薬タイミング"を操作するという簡潔・明快な方法によって,現在の治療法と比較しても治療成績の向上が期待できる時間薬物療法を,多くの疾患に臨床応用できるようにしたいと考え,基礎研究や臨床研究を行っています.

Research Fields, Keywords

chronotherapy
clinical pharmacology

Field of expertise (Grants-in-aid for Scientific Research classification)

Chronopharmacology
Clinical Pharmacology

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6 Similar Profiles

1 Active
7 Finished

アトピー性皮膚炎固有の概日リズムを基盤とした新規治療法の開発
To, H. (Principal Investigator)
Japan Society for the Promotion of Science
2025/04/01 → 2028/03/31
Project: Research Project
生体リズムを考慮した抗リウマチ薬ヤヌスキナーゼ阻害剤の至適投与設計の構築
To, H. (PI)
2019/04/01 → 2022/03/31
Project: Research
Application of chronotherapy to decrease the drug-induced peripheral neuropathy
To, H. (PI)
2016/04/01 → 2019/03/31
Project: Research
Application of chronotherapy of antirheumatic drug to perform proper therapy
To, H. (PI)
2012/04/01 → 2014/03/31
Project: Research
薬物間相互作用および腫瘍の生体リズムを基盤とした個別化治療予測システムの開発
To, H. (PI)
2008/04/01 → 2010/03/31
Project: Research

85 Article
18 Presentation
2 Review article

Population pharmacokinetic analysis identifies an absorption process model for mycophenolic acid in patients with renal transplant
Suzuki, Y., Matsunaga, N., Aoyama, T., Ogami, C., Hasegawa, C., Iida, S., To, H., Kitahara, T. & Tsuji, Y., 2024/12, In: Clinical and Translational Science. 17, 12, e70097.
Research output: Contribution to journal › Article › peer-review

Open Access
鼻粘液pHの生理的変動が弱酸性薬物含有粉末製剤の鼻腔内溶出挙動に与える影響
島田陸斗, 井上大輔, 瀬戸祥弘 & 藤秀人, 2024.
Research output: Contribution to conference › Presentation
Comparison of the efficacy of anti-diabetic medications as add-on to metformin in type 2 diabetes mellitus from a real-world database
Ono, R., Ogami, C., Hasegawa, C., To, H., Matsumoto, Y. & Tsuji, Y., 2023/12, In: BMC Pharmacology and Toxicology. 24, 1, 75.
Research output: Contribution to journal › Article › peer-review

Open Access
1 Scopus citations
Dissolution behavior analysis of solid formulations for nasal application under intranasal physiological environment
Shimada, R., Inoue, D., Seto, Y. & To, H., 2023.
Research output: Contribution to conference › Presentation
Population Pharmacokinetic Model for Unbound Concentrations of Daptomycin in Patients with MRSA Including Patients Undergoing Hemodialysis
Takahashi, S., Tsuji, Y., Holford, N., Ogami, C., Kasai, H., Kawasuji, H., To, H. & Yamamoto, Y., 2023/03, In: European Journal of Drug Metabolism and Pharmacokinetics. 48, 2, p. 201-211 11 p.
Research output: Contribution to journal › Article › peer-review
1 Scopus citations

Influence of dosing times on cisplatin-induced peripheral neuropathy in rats
Seto, Y. (Creator), Okazaki, F. (Creator), Horikawa, K. (Creator), Zhang, J. (Creator), Sasaki, H. (Creator) & To, H. (Creator), figshare, 2016
DOI: 10.6084/m9.figshare.c.3630242.v1, https://springernature.figshare.com/collections/Influence_of_dosing_times_on_cisplatin-induced_peripheral_neuropathy_in_rats/3630242/1
Dataset
CCDC 1857984: Experimental Crystal Structure Determination
Fukuda, T. (Creator), Nanjo, Y. (Creator), Fujimoto, M. (Creator), Yoshida, K. (Creator), Natsui, Y. (Creator), Ishibashi, F. (Creator), Okazaki, F. (Creator), To, H. (Creator) & Iwao, M. (Creator), Cambridge Crystallographic Data Centre, 2018
DOI: 10.5517/ccdc.csd.cc20cczr, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc20cczr&sid=DataCite
Dataset
Influence of dosing times on cisplatin-induced peripheral neuropathy in rats
Seto, Y. (Creator), Okazaki, F. (Creator), Horikawa, K. (Creator), Zhang, J. (Creator), Sasaki, H. (Creator) & To, H. (Creator), figshare, 2016
DOI: 10.6084/m9.figshare.c.3630242, https://springernature.figshare.com/collections/Influence_of_dosing_times_on_cisplatin-induced_peripheral_neuropathy_in_rats/3630242
Dataset
Additional file 3: of Influence of dosing times on cisplatin-induced peripheral neuropathy in rats
Seto, Y. (Creator), Okazaki, F. (Contributor), Horikawa, K. (Creator), Zhang, J. (Creator), Sasaki, H. (Creator) & To, H. (Creator), figshare, 2016
DOI: 10.6084/m9.figshare.c.3630242_d1, https://springernature.figshare.com/articles/presentation/Additional_file_3_of_Influence_of_dosing_times_on_cisplatin-induced_peripheral_neuropathy_in_rats/4421537
Dataset
Additional file 3: of Influence of dosing times on cisplatin-induced peripheral neuropathy in rats
Seto, Y. (Creator), Okazaki, F. (Contributor), Horikawa, K. (Creator), Zhang, J. (Creator), Sasaki, H. (Creator) & To, H. (Creator), figshare, 2016
DOI: 10.6084/m9.figshare.c.3630242_d1.v1, https://springernature.figshare.com/articles/presentation/Additional_file_3_of_Influence_of_dosing_times_on_cisplatin-induced_peripheral_neuropathy_in_rats/4421537/1
Dataset

第9回臨床薬理研究振興財団　研究大賞
To, H. (Recipient), 2016/04
Prize
臨床薬理研究財団賞　学術奨励賞
To, H. (Recipient), 2014/11
Prize
日本時間生物学会　奨励賞
To, H. (Recipient), 2013/11
Prize
第34回日本臨床薬理学会学術総会　優秀演題賞
To, H. (Recipient), 2013/12
Prize
優秀ポスター賞
To, H. (Recipient), 2010/07
Prize

33 Oral presentation
9 Academic activities
8 social activities

第38回富山市民大学祭特別講演会
To, H. (Participant)
2018/12
Activity: Other › social activities
富山大学サテライト講座
To, H. (Participant)
2018/12
Activity: Other › social activities
教員免許状更新講習
To, H. (Participant)
2016/08
Activity: Other › social activities
b 生体リズムを基盤とした抗リウマチ薬の至適投与法の構築 /b
To, H. (Speaker)
2016
Activity: Talk or presentation › Oral presentation
日本TDM学会 (External organization)
To, H. (Member)
2014/05 → …
Activity: Membership › Academic activities

薬物動態学特論
Hosoya, K.-I., Hashimoto, Y., Taguchi, M. & To, H.
2024/10/02 → 2024/12/03
Course
薬局実習【科目用履修生用】
To, H.
2024/10/01 → 2025/03/31
Course
臨床前実習Ⅰ
To, H., Seto, Y. & Inoue, D.
2024/10/01 → 2025/03/31
Course
専門英語Ⅱ（神経機能学領域）
To, H. & Tohda, C.
2024/10/01 → 2025/03/31
Course
卒業研究（医療薬学）薬6年用
To, H.
2024/10/01 → 2025/03/31
Course

Hideto To

Personal profile

Campus career

Affiliated academic society

Research interests

Research Fields, Keywords

Field of expertise (Grants-in-aid for Scientific Research classification)

Fingerprint

Collaborations and top research areas from the last five years

Dive into details

アトピー性皮膚炎固有の概日リズムを基盤とした新規治療法の開発

生体リズムを考慮した抗リウマチ薬ヤヌスキナーゼ阻害剤の至適投与設計の構築

Application of chronotherapy to decrease the drug-induced peripheral neuropathy

Application of chronotherapy of antirheumatic drug to perform proper therapy

薬物間相互作用および腫瘍の生体リズムを基盤とした個別化治療予測システムの開発

Population pharmacokinetic analysis identifies an absorption process model for mycophenolic acid in patients with renal transplant

鼻粘液pHの生理的変動が弱酸性薬物含有粉末製剤の鼻腔内溶出挙動に与える影響

Comparison of the efficacy of anti-diabetic medications as add-on to metformin in type 2 diabetes mellitus from a real-world database

Dissolution behavior analysis of solid formulations for nasal application under intranasal physiological environment

Population Pharmacokinetic Model for Unbound Concentrations of Daptomycin in Patients with MRSA Including Patients Undergoing Hemodialysis

Influence of dosing times on cisplatin-induced peripheral neuropathy in rats

CCDC 1857984: Experimental Crystal Structure Determination

Influence of dosing times on cisplatin-induced peripheral neuropathy in rats

Additional file 3: of Influence of dosing times on cisplatin-induced peripheral neuropathy in rats

Additional file 3: of Influence of dosing times on cisplatin-induced peripheral neuropathy in rats

第9回臨床薬理研究振興財団　研究大賞

臨床薬理研究財団賞　学術奨励賞

日本時間生物学会　奨励賞

第34回日本臨床薬理学会学術総会　優秀演題賞

優秀ポスター賞

第38回富山市民大学祭特別講演会

富山大学サテライト講座

教員免許状更新講習

b 生体リズムを基盤とした抗リウマチ薬の至適投与法の構築 /b

日本TDM学会 (External organization)

薬物動態学特論

薬局実習【科目用履修生用】

臨床前実習Ⅰ

専門英語Ⅱ（神経機能学領域）

卒業研究（医療薬学）薬6年用

Hideto To

Personal profile

Campus career

Affiliated academic society

Research interests

Research Fields, Keywords

Field of expertise (Grants-in-aid for Scientific Research classification)

Fingerprint

Collaborations and top research areas from the last five years

Projects

Research output

Datasets

Prizes

Activities

Courses