Projects per year
- 300 - 350 out of 384 results
Search results
-
Finished
Elucidation of the unidentified molecular structure of the cell volume-sensitive anion channel
Sakai, H. (PI) & Shimizu, T. (CoI)
2012/04/01 → 2014/03/31
Project: Research
-
Molecular mechanism and pathophysiology of nucleophagy induced by cation pump
Fujii, T. (PI)
2012/04/01 → 2014/03/31
Project: Research
-
Neural activity-dependent attenuation of PGE2 elimination across the blood-brain barrier and molecular mechanisms of this attenuation
Akanuma, S.-I. (PI)
2012/04/01 → 2014/03/31
Project: Research
-
Enhanced PDGF signaling contributes adipose tissue angiogenesis, expansion, and systemic glucose intolerance in obesity.
Wada, T. (PI), Sasaoka, T. (CoI), Sasahara, M. (CoI) & Ishii, Y. (CoI)
2012/04/01 → 2015/03/31
Project: Research
-
Variability of bioavailability and intestinal absorption mechanism of mizoribine and bisoprolol
Hashimoto, Y. (PI), Takashi, N. (CoI) & Ishida, K. (CoI)
2012/04/01 → 2015/03/31
Project: Research
-
Development of therapeutics for diabetes with dysregulation of sleep/wake rhythm and depressive disorders by timed regulation of hypothalamic orexin system
Sasaoka, T. (PI), Tsuneki, H. (CoI) & Wada, T. (CoI)
2012/04/01 → 2016/03/31
Project: Research
-
How do Kampo formulations work?
Saiki, I. (PI) & Yokoyama, S. (CoI)
2012/04/01 → 2015/03/31
Project: Research
-
Application of chronotherapy of antirheumatic drug to perform proper therapy
To, H. (PI)
2012/04/01 → 2014/03/31
Project: Research
-
-
Exploratory Research for crude drugs having activated platelet-mediated inhibiting effect on diabetic microangiopathy
Shibahara, N. (PI)
2012/04/01 → 2015/03/31
Project: Research
-
Molecular mechanisms of prostaglandin elimination across brain barriers and its application to neural inflammatory diseases
Hosoya, K.-I. (PI), Kubo, Y. (CoI), Tachikawa, M. (CoI) & Akanuma, S.-I. (CoI)
2012/04/01 → 2014/03/31
Project: Research
-
Structural basis of the filament formation of ESCRT-III proteins
Obita, T. (PI)
2012/04/01 → 2014/03/31
Project: Research
-
Verification of the connector function of the transcription and splicing factor PQBP1
Mizuguchi, M. (PI) & Obita, T. (CoI)
2012/04/01 → 2015/03/31
Project: Research
-
What is the melanoma-specific function of novel mutant MITF?
Yokoyama, S. (PI)
2012/04/01 → 2015/03/31
Project: Research
-
Daily rhythmic regulation of glucose metabolism by hypothalamic orexin system: a chronotherapeutic target for type 2 diabetes
Tsuneki, H. (PI) & Sasaoka, T. (CoI)
2012/04/01 → 2015/03/31
Project: Research
-
Construction of a program for sustainable use of traditional medicines, based on integrated study of genetic, chemical and pharmacological diversity of medicinal plants
Komatsu, K. (PI), Tohda, C. (CoI), Kadowaki, M. (CoI), Zhu, S. (CoI) & Kazuma, K. (CoI)
2012/04/01 → 2015/03/31
Project: Research
-
Asymmetric syntheses of biologically active heterocyclic natural products employing catalytic C-H activation strategy
Nambu, H. (Principal Investigator)
Japan Society for the Promotion of Science
2012/04/01 → 2015/03/31
Project: Research Project
-
Role of TNF-TAK1 signaling pathway in tumor microenvironments of metastasis
Sakurai, H. (PI) & Saiki, I. (CoPI)
2011/04/28 → 2015/03/31
Project: Research
-
Oncogenic mechanism of gastro-intestinal stromal tumore using temperature-sensitive transformed Cajal cells
Sugiyama, T. (PI), Koizumi, K. (CoI) & Ando, T. (CoI)
2011/04/28 → 2015/03/31
Project: Research
-
Detection of novel actions of kampo medicines for lipid metabolism by lipidomic analysis
Watanabe, S. (PI) & Tsuneyama, K. (CoI)
2011/04/01 → 2014/03/31
Project: Research
-
Design, synthesis, and biological evaluation of iminosugars as pharmacological chaperone for Gaucher disease
Kato, A. (PI), Takahata, H. (CoPI), Hirono, S. (CoPI), Ishii, S. (CoPI) & Adachi, I. (CoPI)
2011/04/01 → 2014/03/31
Project: Research
-
Re-evaluation of pathophysiology of normal pregnancy and complicated pregnancy from the viewpoint of immune tolerance
Saito, S. (PI), Takizawa, T. (CoI) & Tabuchi, Y. (CoI)
2011/04/01 → 2015/03/31
Project: Research
-
Molecular basis of epigenetic regulation by ultrasound
Tabuchi, Y. (PI), Kondo, T. (CoI), Wada, S. (CoI) & Ikegame, M. (CoI)
2011/04/01 → 2014/03/31
Project: Research
-
Recovery from spinal cord injury in the chronic phase -the mechanism of denosomin, a novel compound with multiactivities-
Tohda, C. (PI), Matsuya, Y. (CoI), Kuboyama, T. (CoI) & Teshigawara, K. (CoI)
2011/04/01 → 2014/03/31
Project: Research
-
Elucidation of regulatory mechanisms of prevention of influenza A virus infection by functional polysaccharides from food resources
Lee, J. (PI) & Hayashi, K. (CoPI)
2011/04/01 → 2014/03/31
Project: Research
-
-
Development of a new therapeutics of gestational diabetes by inhibition of the central action of lipid phosphatase
Sasaoka, T. (PI), Tsuneki, H. (CoI) & Wada, T. (CoI)
2011/04/01 → 2013/03/31
Project: Research
-
Development and biological application of sulfo-click type reactions
Hatanaka, Y. (PI) & Chiba, J. (CoI)
2011/04/01 → 2014/03/31
Project: Research
-
-
炎症シグナルによるＥｒｂＢチロシンキナーゼのＳｅｒ／Ｔｈｒリン酸化とがん悪性化
Sakurai, H. (Principal Investigator)
Japan Society for the Promotion of Science
2011/04/01 → 2013/03/31
Project: Public
-
Development of a new pancreatic cancer curative medicine from arctigenin, an ingredient of Wakan-yaku 'Burdock Fruit (Seeds of Arctium lappa)'
Tezuka, Y. (PI), Toyooka, N. (CoI) & Awale, S. (CoI)
2010/04/01 → 2013/03/31
Project: Research
-
Inhibition activities of iminosugars against glycoprotein processing
Adachi, I. (PI), Takahata, H. (CoI) & Kato, A. (CoI)
2010/04/01 → 2012/03/31
Project: Research
-
Linkage of neuronal morphology to gene expression:actin-bound transcription cofactor MKL and its regulation by BDNF
Tabuchi, A. (PI)
2010/04/01 → 2013/03/31
Project: Research
-
-
Clinical pharmacokinetic trials in pediatric patients based on a peak-and-trough sampling design
Taguchi, M. (PI)
2010/04/01 → 2012/03/31
Project: Research
-
Peroxisomal dysfunction and ER stress -A novel mechanism for the demyelination in central nervous system-
Morita, M. (PI)
2010/04/01 → 2013/03/31
Project: Research
-
Impact of obesity-induced dysregulation of renin-angiotensin-aldosterone system in the hypothalamus on the homeostasis of energy metabolism.
Wada, T. (PI)
2010/04/01 → 2012/03/31
Project: Research
-
天然変性タンパク質の動的構造解析
Akashi, S. (PI), Sugase, K. (CoI), Mizuguchi, M. (CoI) & Nishimura, Y. (CoI)
2009/07/23 → 2014/03/31
Project: Research
-
Development of Au-catalyzed tandem cyclization reaction and its application to syntheses of biologically active alkaloids.
Sugimoto, K. (PI)
2009/04/01 → 2011/03/31
Project: Research
-
Studies for the detail mechanisms of depression onset and the development of novel antidepressants based on 'the Wakan-yaku, Sino-Japanese traditional medicine, theory'
Toda, M. (PI), Komatsu, K. (CoI), Namiki, T. (CoI), Goto, H. (CoI), Tohda, C. (CoI), Chung, M. H. (CoI), Yokawa, T. (CoI) & Sukma, M. (CoI)
2009/04/01 → 2014/03/31
Project: Research
-
Synthetic Studies on Marine Alkaloid of Batzellasides Directed toward Novel Antidiabetic Drug
Toyooka, N. (PI), Kato, A. (CoI) & Adachi, I. (CoI)
2009/04/01 → 2012/03/31
Project: Research
-
-
Neutron crystallographic analysis of human transthyretin
Yokoyama, T. (PI)
2009/04/01 → 2012/03/31
Project: Research
-
Segmental labeling of the intrinsically disordered protein PQBP1 and elucidation of the molecular recognition mechanism by NMR
Mizuguchi, M. (PI)
2009/04/01 → 2012/03/31
Project: Research
-
Development of wavelength-dependent fluorolabel transfer method to functional domain of target protein
Tomohiro, T. (PI) & Hatanaka, Y. (CoI)
2009/04/01 → 2012/03/31
Project: Research
-
Involvement of hypothalamic orexin in the development of insulin resistance associated with depression
Tsuneki, H. (PI) & Sasaoka, T. (CoI)
2009/04/01 → 2012/03/31
Project: Research
-
-
Development and application of multi-functional hybrid-type organocatalysts based on hypervalent iodine oxidation
Yakura, T. (PI)
2009/04/01 → 2012/03/31
Project: Research
-
-
Clarification of the mechanism by which the impairment of intra-hepatic cellular network caused hepatic insulin resistance in mice.
Wada, T. (PI)
2008/04/01 → 2010/03/31
Project: Research