Projects per year
Personal profile
Campus career
工学科 助教 2019/04/01-2019/09/30
機能性分子創成変換システム学系 助教 2019/04/01-2019/09/30
工学系 助教 2019/10/01-
工学科 助教 2019/10/01-
工学部工学科 基幹教員
学部運営への参画状況・・・有-教授会
担当授業科目に係る状況・・・主要授業科目担当
機能性分子創成変換システム学系 助教 2019/04/01-2019/09/30
工学系 助教 2019/10/01-
工学科 助教 2019/10/01-
工学部工学科 基幹教員
学部運営への参画状況・・・有-教授会
担当授業科目に係る状況・・・主要授業科目担当
Affiliated academic society
有機合成化学協会
日本薬学会
日本薬学会
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 1 Finished
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Synthetic studies on broussonetine N aimed at creating novel glycosidase inhibitors
Okada, T. (PI)
2019/08/30 → 2021/03/31
Project: Research
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Construction of trans-2,6-Disubstituted Piperidine Skeleton and Its Application to the Total Synthesis of (−)-Myrtine and trans-Piperidine-Type Poison-Frog Alkaloids
Okada, T., Eguchi, K., Hasegawa, F., Ikhlaq, M. M., Yoshikawa, T. & Toyooka, N., 2025/02/21, In: Journal of Organic Chemistry. 90, 7, p. 2749-2759 11 p.Research output: Contribution to journal › Article › peer-review
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Divergent total synthesis of natural products bearing isoflavone and 2-oxabicyclo[3.3.1]nonane skeleton using phloroglucinol and their application in drug discovery
Okada, T., Mizuguchi, M., Yokoyama, T., Awale, S. & Toyooka, N., 2025, (Accepted/In press) Advances in Heterocyclic Chemistry. Academic Press Inc., (Advances in Heterocyclic Chemistry).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
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HMGB1 derived from macrophages and enteric glial cells contributes to the butyrate-induced colonic hypersensitivity in mice
Tsubota, M., Sasaki, K., Shin, E., Okamura, Y., Nishimura, A., Yamagata, A., Nonaka, Y., Sekiguchi, F., Tomono, Y., Nishibori, M., Okada, T., Toyooka, N. & Kawabata, A., 2025/07/15, In: European Journal of Pharmacology. 999, 177660.Research output: Contribution to journal › Article › peer-review
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Repurposing of Agrochemicals as ATTRv Amyloidosis Inhibitors
Yokoyama, T., Fujiwara, S., Nishikubo, K., Mizuguchi, M., Nabeshima, Y., Toyooka, N., Okada, T. & Nakagawa, Y., 2025/01/23, In: Journal of Medicinal Chemistry. 68, 2, p. 1572-1586 15 p.Research output: Contribution to journal › Article › peer-review
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Spinal pituitary adenylate cyclase-activating polypeptide and PAC1 receptor signaling system is involved in the oxaliplatin-induced acute cold allodynia in mice
Takasaki, I., Nagashima, R., Ueda, T., Ashihara, Y., Nakamachi, T., Okada, T., Toyooka, N., Miyata, A. & Kurihara, T., 2025/02, In: Journal of Pain. 27, 104751.Research output: Contribution to journal › Article › peer-review
Datasets
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Crystal structure of V30M mutated transthyretin in complex with 8-chloro-9-oxo-9H-xanthene-3-carboxylic acid
Kitakami, R. (Contributor), Inui, K. (Contributor), Nakagawa, Y. (Contributor), Sawai, Y. (Contributor), Katayama, W. (Contributor), Yokoyama, T. (Contributor), Okada, T. (Contributor), Kanamitsu, K. (Contributor), Nakagawa, S. (Contributor), Toyooka, N. (Contributor) & Mizuguchi, M. (Contributor), Protein Data Bank (PDB), 2021/10/13
DOI: 10.2210/pdb7EJR/pdb, https://www.wwpdb.org/pdb?id=pdb_00007ejr
Dataset
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Crystal structure of human transthyretin in complex with 4-chloro-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid
Kitakami, R. (Contributor), Inui, K. (Contributor), Nakagawa, Y. (Contributor), Sawai, Y. (Contributor), Katayama, W. (Contributor), Yokoyama, T. (Contributor), Okada, T. (Contributor), Kanamitsu, K. (Contributor), Nakagawa, S. (Contributor), Toyooka, N. (Contributor) & Mizuguchi, M. (Contributor), Protein Data Bank (PDB), 2021/10/13
DOI: 10.2210/pdb7DT3/pdb, https://www.wwpdb.org/pdb?id=pdb_00007dt3
Dataset
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Crystal structure of human transthyretin in complex with 4-chloro-9-oxo-9H-xanthene-2-carboxylic acid
Kitakami, R. (Contributor), Inui, K. (Contributor), Nakagawa, Y. (Contributor), Sawai, Y. (Contributor), Katayama, W. (Contributor), Yokoyama, T. (Contributor), Okada, T. (Contributor), Kanamitsu, K. (Contributor), Nakagawa, S. (Contributor), Toyooka, N. (Contributor) & Mizuguchi, M. (Contributor), Protein Data Bank (PDB), 2021/10/13
DOI: 10.2210/pdb7DT5/pdb, https://www.wwpdb.org/pdb?id=pdb_00007dt5
Dataset
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Crystal structure of V30M mutated transthyretin in complex with purpurin
Kitakami, R. (Contributor), Inui, K. (Contributor), Nakagawa, Y. (Contributor), Sawai, Y. (Contributor), Katayama, W. (Contributor), Yokoyama, T. (Contributor), Okada, T. (Contributor), Kanamitsu, K. (Contributor), Nakagawa, S. (Contributor), Toyooka, N. (Contributor) & Mizuguchi, M. (Contributor), Protein Data Bank (PDB), 2021/10/13
DOI: 10.2210/pdb7DT6/pdb, https://www.wwpdb.org/pdb?id=pdb_00007dt6
Dataset
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Crystal structure of human transthyretin in complex with 8-chloro-9-oxo-9H-xanthene-3-carboxylic acid
Kitakami, R. (Contributor), Inui, K. (Contributor), Nakagawa, Y. (Contributor), Sawai, Y. (Contributor), Katayama, W. (Contributor), Yokoyama, T. (Contributor), Okada, T. (Contributor), Kanamitsu, K. (Contributor), Nakagawa, S. (Contributor), Toyooka, N. (Contributor) & Mizuguchi, M. (Contributor), Protein Data Bank (PDB), 2021/10/13
DOI: 10.2210/pdb7EJQ/pdb, https://www.wwpdb.org/pdb?id=pdb_00007ejq
Dataset
Courses
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生命工学実験Ⅳ
Ozawa, T., Toyooka, N., Kurosawa, N., Sayama, M., Suga, M., Kurooka, T., Kawahara, S., Moriwaki, M., Inobe, T., Iwanaga, S., Takasaki, I., Okada, T. & Koike, S. 2024/10/01 → 2025/03/31
Course
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工学倫理／生命
Ozawa, T., Toyooka, N., Kurosawa, N., Sayama, M., Suga, M., Kurooka, T., Kawahara, S., Moriwaki, M., Inobe, T., Iwanaga, S., Takasaki, I., Okada, T. & Koike, S. 2024/10/01 → 2025/03/31
Course
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生命工学実験Ⅲ
Ozawa, T., Toyooka, N., Kurosawa, N., Sayama, M., Suga, M., Kurooka, T., Kawahara, S., Moriwaki, M., Inobe, T., Iwanaga, S., Takasaki, I., Okada, T., Koike, S. & Kurooka, T. 2024/10/01 → 2025/03/31
Course
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工学基礎実験
Ozawa, T., Toyooka, N., Kurosawa, N., Sayama, M., Suga, M., Kurooka, T., Kawahara, S., Moriwaki, M., Inobe, T., Iwanaga, S., Takasaki, I., Okada, T. & Koike, S. 2024/10/01 → 2025/03/31
Course
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創造ものづくり／生命
Ozawa, T., Toyooka, N., Kurosawa, N., Sayama, M., Suga, M., Kurooka, T., Kawahara, S., Moriwaki, M., Inobe, T., Iwanaga, S., Takasaki, I., Okada, T. & Koike, S. 2024/10/01 → 2025/03/31
Course