薬化学研究室

2025

Development of pH-responsive crosslinked peptides that form stable α-helices under weakly acidic conditions

Amano, M., Chiba, J., Yasukagawa, T., Yokoyama, S., Zhou, Y., Ohishi, Y. & Inouye, M., 2025/01, In: Chemistry Letters. 54, 1

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

2024

A Versatile Synthetic Method for Photophysically and Chemically Stable [5]Rotaxane-Type Fluorescence Dyes of Various Colors by Using a Cooperative Capture Strategy

Ohishi, Y., Nishioki, K., Miyaoka, Y., Serizawa, K., Sugawara, S., Hayashi, K., Inoue, D., Iwamura, M., Yokoyama, S., Chiba, J. & Inouye, M., 2024/01/25, In: Advanced Optical Materials. 12, 3, 2301457.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

4 被引用数 (Scopus)

Preferential Binding to a Mannoside of a Pyridine–Acetylene–Phenol Macrocycle with a Fluorine Substituent in the Cavity

Ohishi, Y., Chiba, J. & Inouye, M., 2024/12/02, In: European Journal of Organic Chemistry. 27, 45, e202400758.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

ロタキサン型色素の創製と効率的合成法の開拓

Ohishi, Y. & Inouye, M., 2024, In: Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry. 82, 3, p. 257-268 12 p.

研究成果: ジャーナルへの寄稿 › 総説 › 査読

2022

Chiral Assemblies of Planar and Achiral meta-Arylene Ethynylene Macrocycles Induced by Saccharide Recognition

Ohishi, Y., Chiba, J. & Inouye, M., 2022/08/19, In: Journal of Organic Chemistry. 87, 16, p. 10825-10835 11 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

8 被引用数 (Scopus)

Freshly isolated retinal capillaries to determine efflux transporter function at the inner BRB

Tajima, K., Akanuma, S. I., Ohishi, Y., Yoshida, Y., Bauer, B., Kubo, Y., Inouye, M. & Hosoya, K. I., 2022/03, In: Journal of Controlled Release. 343, p. 434-442 9 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

4 被引用数 (Scopus)

Synthesis of Rigid Macrocyclic Phenols and Their Catalytic Applications in Diels-Alder Reactions

Hayashi, T., Ohishi, Y., Chiba, J. & Inouye, M., 2022/08/26, In: European Journal of Organic Chemistry. 2022, 32, e202200136.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

2021

Saccharide Recognition by a Three-Arm-Shaped Host Having Preorganized Three-Dimensional Hydrogen-Bonding Sites

Ohishi, Y., Masuda, K., Kudo, K., Abe, H. & Inouye, M., 2021/01/07, In: Chemistry - A European Journal. 27, 2, p. 785-793 9 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

11 被引用数 (Scopus)

2020

2-Aminopyridine as a Nucleobase Substitute for Adenine in DNA-like Architectures: Synthesis of Alkynyl C-Nucleotides and Their Hybridization Characteristics

Kurosaki, F., Chiba, J., Oda, Y., Hino, A. & Inouye, M., 2020/02/21, In: Journal of Organic Chemistry. 85, 4, p. 2666-2671 6 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

A Pyridine-Acetylene-Aniline Oligomer: Saccharide Recognition and Influence of this Recognition Array on the Activity as Acylation Catalyst

Ohishi, Y., Takata, T. & Inouye, M., 2020/12, In: ChemPlusChem. 85, 12, p. 2565-2569 5 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

8 被引用数 (Scopus)

Preferential Recognition and Extraction to Pentoses over Hexoses by a D_{6 h}-Symmetrical Ethynylphenol Macrocycle with Six Inner Phenolic Hydroxy Groups

Hayashi, T., Ohishi, Y., Abe, H. & Inouye, M., 2020/02/21, In: Journal of Organic Chemistry. 85, 4, p. 1927-1934 8 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

12 被引用数 (Scopus)

2019

Additive-Free Enzymatic Phosphorylation and Ligation of Artificial Oligonucleotides with C-Nucleosides at the Reaction Points

Oda, Y., Chiba, J., Kurosaki, F., Yamade, Y. & Inouye, M., 2019/08, In: ChemBioChem. 20, 15, p. 1945-1952 8 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

3 被引用数 (Scopus)

Circularly polarized luminescence from pyrene excimers

Ohishi, Y. & Inouye, M., 2019/11/14, In: Tetrahedron Letters. 60, 46, 151232.

研究成果: ジャーナルへの寄稿 › 総説 › 査読

57 被引用数 (Scopus)

Enantioselective Solid-Liquid Extraction of Native Saccharides with Chiral BINOL-Based Pyridine-Phenol Type Macrocycles

Ohishi, Y., Murase, M., Abe, H. & Inouye, M., 2019/08/16, In: Organic Letters. 21, 16, p. 6202-6207 6 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

17 被引用数 (Scopus)

Novel coupling reaction between sulfonyl azide and N,N,N',N'-tetramethylthiourea

Aswad, M., Chiba, J., Hatanaka, Y. & Tomohiro, T., 2019/06/13, In: Tetrahedron Letters. 60, 24, p. 1611-1613 3 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

3 被引用数 (Scopus)

Photoinduced Electron Transfer-Regulated Protein Labeling With a Coumarin-Based Multifunctional Photocrosslinker

Hotta, Y., Kaneko, T., Hayashi, R., Yamamoto, A., Morimoto, S., Chiba, J. & Tomohiro, T., 2019/02/01, In: Chemistry - An Asian Journal. 14, 3, p. 398-402 5 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

7 被引用数 (Scopus)

2018

Design and synthesis of a DNA-like structure composed of alkynyl C-nucleotide with 2-aminopyrimidin-4-one as a nucleobase

Kurosaki, F., Chiba, J. & Inouye, M., 2018, In: Heterocycles. 97, 2, p. 1149-1156 8 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

2 被引用数 (Scopus)

Metathesis-Based Stapling of a Pyridine–Acetylene–Phenol Oligomer Having Alkenyl Side Chains after Intermolecular Templation by Native Saccharides

Abe, H., Sato, C., Ohishi, Y. & Inouye, M., 2018/06/29, In: European Journal of Organic Chemistry. 2018, 24, p. 3131-3138 8 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

9 被引用数 (Scopus)

Nonplanar Macrocycle Consisting of Four Pyridine and Phenol Units Connected with Acetylene Bonds Displaying Preferential Binding to Maltoside over Monosaccharides

Ohishi, Y., Yamamoto, N., Abe, H. & Inouye, M., 2018/05/18, In: Journal of Organic Chemistry. 83, 10, p. 5766-5770 5 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

11 被引用数 (Scopus)

Observation of Circularly Polarized Luminescence of the Excimer from Two Perylene Cores in the Form of [4]Rotaxane

Hayashi, K., Miyaoka, Y., Ohishi, Y., Uchida, T. A., Iwamura, M., Nozaki, K. & Inouye, M., 2018/10/01, In: Chemistry - A European Journal. 24, 55, p. 14613-14616 4 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

40 被引用数 (Scopus)

Spontaneous Helix Formation of " meta"-Ethynylphenol Oligomers by Sequential Intramolecular Hydrogen Bonding inside the Cavities

Hayashi, T., Ohishi, Y., Hee-Soo, S., Abe, H., Matsumoto, S. & Inouye, M., 2018/08/03, In: Journal of Organic Chemistry. 83, 15, p. 8724-8730 7 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

7 被引用数 (Scopus)

Synthesis of alkynyl C-nucleotide triphosphates toward enzymatic elongation of artificial DNA

Oda, Y., Chiba, J. & Inouye, M., 2018, In: Heterocycles. 97, 1, p. 612-620 9 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

2 被引用数 (Scopus)

2017

Saccharide Recognition and Helix Formation in Water with an Amphiphilic Pyridine–Phenol Alternating Oligomer

Ohishi, Y., Abe, H. & Inouye, M., 2017/12/15, In: European Journal of Organic Chemistry. 2017, 46, p. 6975-6979 5 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

20 被引用数 (Scopus)

Simple Synthesis of Sulfonyl Amidine-Containing Glucosidase Inhibitors by a Chemoselective Coupling Reaction Between D-Gluconothiolactam and Sulfonyl Azides

Aswad, M., Chiba, J., Tomohiro, T. & Hatanaka, Y., 2017/06/01, In: International Research Journal of Pure and Applied Chemistry. 14, 2, p. 1-8 8 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

2016

D_3h-Symmetrical Shape-Persistent Macrocycles Consisting of Pyridine–Acetylene–Phenol Conjugates as an Efficient Host Architecture for Saccharide Recognition

Abe, H., Yoneda, T., Ohishi, Y. & Inouye, M., 2016/12/23, In: Chemistry - A European Journal. 22, 52, p. 18944-18952 9 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

22 被引用数 (Scopus)

Evaluation of dipole moment and electrophilicity on the nature of click-type coupling reaction between thioamide and sulfonyl azide

Aswad, M., Chiba, J., Tomohiro, T. & Hatanaka, Y., 2016/03/23, In: Tetrahedron Letters. 57, 12, p. 1313-1316 4 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

8 被引用数 (Scopus)

Helical structure stabilization of functionalized meta-ethynylpyridine polymers and oligomers

Abe, H., Ohishi, Y. & Inouye, M., 2016, In: Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry. 74, 3, p. 254-265 12 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

2 被引用数 (Scopus)

Syndecan-4 Is a Receptor for Clathrin-Mediated Endocytosis of Arginine-Rich Cell-Penetrating Peptides

Kawaguchi, Y., Takeuchi, T., Kuwata, K., Chiba, J., Hatanaka, Y., Nakase, I. & Futaki, S., 2016/04/20, In: Bioconjugate Chemistry. 27, 4, p. 1119-1130 12 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

114 被引用数 (Scopus)

2015

A firmly hybridizable, DNA-like architecture with DAD/ADA- and ADD/DAA-type nonnatural base pairs as an extracellular genetic candidate

Shirato, W., Chiba, J. & Inouye, M., 2015/04/25, In: Chemical Communications. 51, 32, p. 7043-7046 4 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

11 被引用数 (Scopus)

A new class of structurally simple and highly emissive fluorophores with a pyridine-acetylene-phenol conjugate

Ohishi, Y., Abe, H. & Inouye, M., 2015, In: Heterocycles. 90, 1, p. 515-528 14 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

6 被引用数 (Scopus)

Native Mannose-Dominant Extraction by Pyridine-Phenol Alternating Oligomers Having an Extremely Efficient Repeating Motif of Hydrogen-Bonding Acceptors and Donors

Ohishi, Y., Abe, H. & Inouye, M., 2015/11/01, In: Chemistry - A European Journal. 21, 46, p. 16504-16511 8 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

29 被引用数 (Scopus)

Synthesis of nonnatural oligonucleotides made exclusively of alkynyl C-nucleosides with nonnatural bases

Chiba, J. & Inouye, M., 2015, In: Current Protocols in Nucleic Acid Chemistry. 2015, p. 4.62.1-4.62.22

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

6 被引用数 (Scopus)

2014

An isotope-coded fluorogenic cross-linker for high-performance target identification based on photoaffinity labeling

Tomohiro, T., Morimoto, S., Shima, T., Chiba, J. & Hatanaka, Y., 2014/11/07, In: Angewandte Chemie - International Edition. 53, 49, p. 13502-13505 4 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

22 被引用数 (Scopus)

Deformable nature of various damaged DNA duplexes estimated by an electrochemical analysis on electrodes

Chiba, J., Aoki, S., Yamamoto, J., Iwai, S. & Inouye, M., 2014/08/26, In: Chemical Communications. 50, 76, p. 11126-11128 3 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

3 被引用数 (Scopus)

2013

A supramolecular DNA self-assembly based on β-cyclodextrin–adamantane complexation as a bioorthogonal sticky end motif

Chiba, J., Sakai, A., Yamada, S., Fujimoto, K. & Inouye, M., 2013/06/20, In: Chemical Communications. 49, 57, p. 6454-6456 3 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

18 被引用数 (Scopus)

Coupling reaction of thioamides with sulfonyl azides: An efficient catalyst-free click-type ligation under mild conditions

Aswad, M., Chiba, J., Tomohiro, T. & Hatanaka, Y., 2013/10/08, In: Chemical Communications. 49, 87, p. 10242-10244 3 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

42 被引用数 (Scopus)

Identification of cellular proteins interacting with octaarginine (R8) cell-penetrating peptide by photo-crosslinking

Kawaguchi, Y., Tanaka, G., Nakase, I., Imanishi, M., Chiba, J., Hatanaka, Y. & Futaki, S., 2013/07/01, In: Bioorganic and Medicinal Chemistry Letters. 23, 13, p. 3738-3740 3 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

22 被引用数 (Scopus)

Syntheses and electrochemical properties of novel aminopyrimidinone derivatives as a new class of abasic-site binders

Chiba, J., Doi, Y. & Inouye, M., 2013/01, In: Research on Chemical Intermediates. 39, 1, p. 177-183 7 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

1 被引用数 (Scopus)

2012

Concentration- and time-dependent eccentric changes in circular dichroism of saccharide-linked ethynylpyridine oligomer with copper(II) ions

Abe, H., Ohishi, Y. & Inouye, M., 2012/06/01, In: Journal of Organic Chemistry. 77, 11, p. 5209-5214 6 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

13 被引用数 (Scopus)

Electrochemical direct detection of DNA deamination catalyzed by APOBEC3G

Chiba, J., Kouno, T., Aoki, S., Sato, H., Zhang, J. Y., Matsuo, H. & Inouye, M., 2012/11/19, In: Chemical Communications. 48, 99, p. 12115-12117 3 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

7 被引用数 (SciVal)

Furanose ring conformations in a 1′-alkynyl C-nucleoside and the dinucleotide

Chiba, J., Shirato, W., Yamade, Y., Kim, B. S., Matsumoto, S. & Inouye, M., 2012/11/04, In: Tetrahedron. 68, 44, p. 9045-9049 5 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

8 被引用数 (Scopus)

2010

Electrochemical detection of insertion/deletion mutations based on enhanced flexibility of bulge-containing duplexes on electrodes

Chiba, J., Akaishi, A., Ikeda, R. & Inouye, M., 2010/10/28, In: Chemical Communications. 46, 40, p. 7563-7565 3 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

16 被引用数 (SciVal)

Exotic DNAs made of nonnatural bases and natural phosphodiester bonds

Chiba, J. & Inouye, M., 2010/02, In: Chemistry and Biodiversity. 7, 2, p. 259-282 24 p.

研究成果: ジャーナルへの寄稿 › 総説 › 査読

20 被引用数 (Scopus)

Hexamethyldisilazane-promoted sonogashira reaction of polyfunctionalized N-containing heterocycles

Inouye, M., Doi, Y., Azuchi, J., Shirato, W., Chiba, J. & Abe, H., 2010/02/28, In: Heterocycles. 82, 2, p. 1137-1141 5 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

9 被引用数 (Scopus)

Specific induced circular dichroism and enhanced B to Z transitions of duplexes stabilized by chromophore-linked alkynylnucleoside residues

Fujimoto, K., Aizawa, S., Oota, I., Chiba, J. & Inouye, M., 2010/02/22, In: Chemistry - A European Journal. 16, 8, p. 2401-2406 6 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

13 被引用数 (Scopus)

2009

Detection of mismatched duplexes by synchronizing the pulse potential frequency with the dynamics of ferrocene/isoquinoline conjugate-connected DNA probes immobilized onto electrodes

Ikeda, R., Kobayashi, S., Chiba, J. & Inouye, M., 2009/05/04, In: Chemistry - A European Journal. 15, 19, p. 4822-4828 7 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

36 被引用数 (SciVal)

Electrochemical genotyping by using two ferrocene/isoquinoline connected DNA probes with different redox potentials on a single electrode

Ikeda, R., Kitagawa, S., Chiba, J. & Inouye, M., 2009/07/20, In: Chemistry - A European Journal. 15, 29, p. 7048-7051 4 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

16 被引用数 (SciVal)

Photo- and electrochemical properties of novel 7-substituted naphthyridine derivatives

Chiba, J., Doi, Y. & Inouye, M., 2009, In: Heterocycles. 79, C, p. 411-415 5 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

2 被引用数 (Scopus)

2008

Artificial DNA made exclusively of nonnatural C-nucleosides with four types of nonnatural bases

Doi, Y., Chiba, J., Morikawa, T. & Inouye, M., 2008/07/09, In: Journal of the American Chemical Society. 130, 27, p. 8762-8768 7 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

65 被引用数 (Scopus)

2007

Artificial DNAs based on alkynyl C-nucleosides as a superior scaffold for homo- and heteroexcimer emissions

Chiba, J., Takeshima, S., Mishima, K., Maeda, H., Nanai, Y., Mizuno, K. & Inouye, M., 2007, In: Chemistry - A European Journal. 13, 29, p. 8124-8130 7 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

55 被引用数 (Scopus)

薬化学研究室

研究成果

検索結果