Electrochemical direct detection of DNA deamination catalyzed by APOBEC3G

Junya Chiba; Takahide Kouno; Shun Aoki; Hitoshi Sato; Jing Ying Zhang; Hiroshi Matsuo; Masahiko Inouye

doi:10.1039/c2cc36779c

Electrochemical direct detection of DNA deamination catalyzed by APOBEC3G

Junya Chiba^*, Takahide Kouno, Shun Aoki, Hitoshi Sato, Jing Ying Zhang, Hiroshi Matsuo, Masahiko Inouye

^*この論文の責任著者

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

7 被引用数 (SciVal)

抄録

APOBEC3G catalyzes deamination of cytosines in HIV-1 genome, and restricts the HIV-1 infection. Here, we propose a picomole-scale assay for the detection of DNA deamination catalyzed by APOBEC3G. Our results show the suitability of the developed method for a time course analysis of enzyme-catalyzed DNA modifications.

本文言語	英語
ページ（範囲）	12115-12117
ページ数	3
ジャーナル	Chemical Communications
巻	48
号	99
DOI	https://doi.org/10.1039/c2cc36779c
出版ステータス	出版済み - 2012/11/19

ASJC Scopus 主題領域

触媒
電子材料、光学材料、および磁性材料
セラミックおよび複合材料
化学一般
表面、皮膜および薄膜
金属および合金
材料化学

UN SDG

この成果は、次の持続可能な開発目標に貢献しています

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10.1039/c2cc36779c

引用スタイル

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abstract = "APOBEC3G catalyzes deamination of cytosines in HIV-1 genome, and restricts the HIV-1 infection. Here, we propose a picomole-scale assay for the detection of DNA deamination catalyzed by APOBEC3G. Our results show the suitability of the developed method for a time course analysis of enzyme-catalyzed DNA modifications.",

author = "Junya Chiba and Takahide Kouno and Shun Aoki and Hitoshi Sato and Zhang, {Jing Ying} and Hiroshi Matsuo and Masahiko Inouye",

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T1 - Electrochemical direct detection of DNA deamination catalyzed by APOBEC3G

AU - Chiba, Junya

AU - Kouno, Takahide

AU - Aoki, Shun

AU - Sato, Hitoshi

AU - Zhang, Jing Ying

AU - Matsuo, Hiroshi

AU - Inouye, Masahiko

PY - 2012/11/19

Y1 - 2012/11/19

N2 - APOBEC3G catalyzes deamination of cytosines in HIV-1 genome, and restricts the HIV-1 infection. Here, we propose a picomole-scale assay for the detection of DNA deamination catalyzed by APOBEC3G. Our results show the suitability of the developed method for a time course analysis of enzyme-catalyzed DNA modifications.

AB - APOBEC3G catalyzes deamination of cytosines in HIV-1 genome, and restricts the HIV-1 infection. Here, we propose a picomole-scale assay for the detection of DNA deamination catalyzed by APOBEC3G. Our results show the suitability of the developed method for a time course analysis of enzyme-catalyzed DNA modifications.

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U2 - 10.1039/c2cc36779c

DO - 10.1039/c2cc36779c

M3 - 学術論文

C2 - 23145435

AN - SCOPUS:84869987555

SN - 1359-7345

VL - 48

SP - 12115

EP - 12117

JO - Chemical Communications

JF - Chemical Communications

IS - 99

ER -

Electrochemical direct detection of DNA deamination catalyzed by APOBEC3G

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UN SDG

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