Projects per year
Personal profile
Campus career
展開ゲノム薬学系 助教 2007/10/01-2019/09/30
薬学科 助教 2007/10/01-2019/09/30
薬学・和漢系 助教 2019/10/01-2021/09/30
薬学科 助教 2019/10/01-2021/09/30
薬学・和漢系 准教授 2021/10/01-
薬学科 准教授 2021/10/01-
薬学部薬学科 基幹教員
学部運営への参画状況・・・有-教授会他
担当授業科目に係る状況・・・主要授業科目担当
薬学科 助教 2007/10/01-2019/09/30
薬学・和漢系 助教 2019/10/01-2021/09/30
薬学科 助教 2019/10/01-2021/09/30
薬学・和漢系 准教授 2021/10/01-
薬学科 准教授 2021/10/01-
薬学部薬学科 基幹教員
学部運営への参画状況・・・有-教授会他
担当授業科目に係る状況・・・主要授業科目担当
Research Fields, Keywords
- Blood-brain barrier
- transporter
Field of expertise (Grants-in-aid for Scientific Research classification)
- Medical pharmacy
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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脳クレアチン供給を実現するモノカルボン酸輸送体認識型プロドラッグ開発とその有用性
Hosoya, K.-I. (Principal Investigator), 立川正憲 (Co-Investigator(Kenkyū-buntansha)), Toyooka, N. (Co-Investigator(Kenkyū-buntansha)) & Akanuma, S.-I. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2023/04/01 → 2026/03/31
Project: Research Project
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Transport mechanisms of cell-penetrating peptides at the blood-retinal barrier to establish strategies of macromolecular drug delivery
Akanuma, S.-I. (Principal Investigator), 泉尾直孝 (Co-Investigator(Kenkyū-buntansha)) & Hosoya, K.-I. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2022/04/01 → 2025/03/31
Project: Research Project
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Influx transport system for nutrients and drugs at the blood-testis barrier and its application
Kubo, Y. (Principal Investigator), Hosoya, K.-I. (Co-Investigator(Kenkyū-buntansha)) & Akanuma, S.-I. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2020/04/01 → 2024/03/31
Project: Research Project
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Study of cationic drug efflux across the blood-retinal barrier
Kubo, Y. (PI) & Akanuma, S.-I. (CoI)
2017/04/01 → 2020/03/31
Project: Research
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In vitro characterization of taurine transport using the human brain microvascular endothelial cell line as a human blood-brain barrier model
Tega, Y., Kawauchi, Y., Akanuma, S. I., Inagaki, M., Tachikawa, M. & Hosoya, K. I., 2025/04, In: Drug Metabolism and Pharmacokinetics. 61, 101040.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Neuroprotective effects of compounds interacting with carrier-mediated amantadine transport across the blood–retinal barrier in rats
Shinozaki, Y., Akanuma, S. I., Tega, Y. & Hosoya, K. I., 2025/04, In: Journal of Pharmacological Sciences. 157, 4, p. 212-218 7 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Blood-to-Testis Transport of Ribavirin Involves Carrier-Mediated Processes at the Blood–Testis Barrier
Ito, T., Kubo, Y., Tega, Y., Akanuma, S. I. & Hosoya, K. I., 2024, (Accepted/In press) In: Journal of Pharmaceutical Sciences.Research output: Contribution to journal › Article › peer-review
Open Access -
Molecular Mechanism of SLC6A8 Dysfunction with c.1699T>C (p.S567P) Mutation in Cerebral Creatine Deficiency Syndromes
Jomura, R., Sawada, M., Tega, Y., Akanuma, S. I., Tachikawa, M. & Hosoya, K. I., 2024/01, In: Biological and Pharmaceutical Bulletin. 47, 1, p. 187-191 5 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Upregulation of P-Glycoprotein and Breast Cancer Resistance Protein Activity in Newly Developed in Vitro Rat Blood–Brain Barrier Spheroids Using Advanced Glycation End-Products
Endo, H., Ogasawara, M., Tega, Y., Kubo, Y., Hosoya, K. I. & Akanuma, S. I., 2024/11, In: Biological and Pharmaceutical Bulletin. 47, 11, p. 1893-1903 11 p.Research output: Contribution to journal › Article › peer-review
Open Access
Datasets
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Processing mechanism of guanidinoacetate in choroid plexus epithelial cells: conversion of guanidinoacetate to creatine via guanidinoacetate N-methyltransferase and monocarboxylate transporter 12-mediated creatine release into the CSF
Jomura, R. (Creator), Akanuma, S.-I. (Creator), Kubo, Y. (Creator), Tachikawa, M. (Creator) & Hosoya, K.-I. (Creator), figshare, 2022
DOI: 10.6084/m9.figshare.c.6030313, https://springernature.figshare.com/collections/Processing_mechanism_of_guanidinoacetate_in_choroid_plexus_epithelial_cells_conversion_of_guanidinoacetate_to_creatine_via_guanidinoacetate_N-methyltransferase_and_monocarboxylate_transporter_12-mediated_creatine_release_into_the_CSF/6030313
Dataset
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Processing mechanism of guanidinoacetate in choroid plexus epithelial cells: conversion of guanidinoacetate to creatine via guanidinoacetate N-methyltransferase and monocarboxylate transporter 12-mediated creatine release into the CSF
Jomura, R. (Creator), Akanuma, S.-I. (Creator), Kubo, Y. (Creator), Tachikawa, M. (Creator) & Hosoya, K.-I. (Creator), figshare, 2022
DOI: 10.6084/m9.figshare.c.6030313.v1, https://springernature.figshare.com/collections/Processing_mechanism_of_guanidinoacetate_in_choroid_plexus_epithelial_cells_conversion_of_guanidinoacetate_to_creatine_via_guanidinoacetate_N-methyltransferase_and_monocarboxylate_transporter_12-mediated_creatine_release_into_the_CSF/6030313/1
Dataset
Courses
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医薬品薬効動態学実習
Hosoya, K.-I., Tabuchi, A., Nitta, A., Sasaoka, T., Hashimoto, Y., To, H., Akanuma, S.-I., So, T., Kume, T., Sakurai, H., Watanabe, S., Shibahara, N., Tohda, C., Koizumi, K., Hayakawa, Y., Nakagawa, Y. & Kim, J. 2024/10/01 → 2025/03/31
Course
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臨床前実習Ⅱ
Kanamori, M., Takamura, A., Takaoka, Y., Nitta, A., Yokose, J., Akanuma, S.-I. & Ihara, D. 2024/10/01 → 2025/03/31
Course
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医薬品薬効動態学実習
Hosoya, K.-I., Tabuchi, A., Nitta, A., Sasaoka, T., Hashimoto, Y., To, H., Akanuma, S.-I., So, T., Kume, T., Sakurai, H., Watanabe, S., Shibahara, N., Tohda, C., Koizumi, K., Hayakawa, Y., Nakagawa, Y. & Kim, J. 2024/10/01 → 2025/03/31
Course