Faculty of Pharmaceutical Sciences

Projects

Projects per year 1996 2012 2013 2014 2015 2016 2018 2019 2020 2021 2022 2023 2024 2025 2029

• 80 Active
• 304 Finished

Projects per year

Search results

• Finished

  Study of cationic drug efflux across the blood-retinal barrier

  Kubo, Y. (PI) & Akanuma, S.-I. (CoI)

  2017/04/01 → 2020/03/31

  Project: Research

• Regulation of mRNA metabolism by the transcription-coupled RNA methyltransferase PCIF1

  Hirose, Y. (PI)

  2017/04/01 → 2020/03/31

  Project: Research

• Comprehensive understanding of the phospholipid flip mechanism in the endoplasmic reticulum and establishment of the control technology of biomembrane dynamics

  Nakano, M. (PI) & Ikeda, K. (CoI)

  2017/04/01 → 2021/03/31

  Project: Research

• Development and biological application of thioamide-click type reactions

  Chiba, J. (PI)

  2017/04/01 → 2020/03/31

  Project: Research

  • Deoxyribonucleic Acid 100%
  • C-nucleosides 83%
  • C-Nucleoside 75%
  • Alkynyl 66%
  • Nucleobase 66%

• Effect of goreisan on rat mesenteric lymphtic vessels.

  Jo, M. (PI)

  2017/04/01 → 2020/03/31

  Project: Research

• 植物由来新規ポリケタイド閉環酵素の探索と物質生産

  Morita, H. (PI)

  2017/04/01 → 2019/03/31

  Project: Research

• カメルーン産薬用植物の抗菌活性成分に関する研究

  Awouafack, M. D. (PI) & Morita, H. (CoI)

  2016/11/07 → 2019/03/31

  Project: Research

• Establishment of highly effective therapy for food allergy by concomitant use of kakkonto with oral immunotherapy

  Yamamoto, T. (PI), Ito, Y. (CoI) & Nagata, Y. (CoI)

  2016/04/01 → 2019/03/31

  Project: Research

• Discovery of natural anticancer agents that inhibit cancer cells' tolerance to nutrition starvation and elucidation of their molecular mechanisms

  Awale, S. (PI)

  2016/04/01 → 2020/03/31

  Project: Research

• Functional interactions between inflammatory signal and growth singaling in the Warburg effect in cancer cells

  Sakurai, H. (PI)

  2016/04/01 → 2018/03/31

  Project: Research

• The foundation of developing drugs for retinal diseases by pharmaceutical drug-repositioning screening based on the distribution manner via the blood-retinal barrier

  Hosoya, K.-I. (PI), Akanuma, S.-I. (CoI), Matsuya, Y. (CoI), Abe, H. (CoI), Ando, T. (CoI) & Kubo, Y. (CoI)

  2016/04/01 → 2019/03/31

  Project: Research

• PKD2L1 cation channels regulate bitter taste reception

  Shimizu, T. (PI)

  2016/04/01 → 2019/03/31

  Project: Research

• Functional Analysis of transcription factor SOX10 in melanoma for norvel therapeutics

  Yokoyama, S. (PI)

  2016/04/01 → 2018/03/31

  Project: Research

• Adrenoleukodystrophy: effect of bone marrow transplantation in abcd1-deficient mouse

  Morita, M. (PI)

  2016/04/01 → 2019/03/31

  Project: Research

• the effects of CD206-positive macrophages on obesity-associated liver tumors

  Usui, I. (PI), Nakagawa, T. (CoPI) & Hayakawa, Y. (CoI)

  2016/04/01 → 2019/03/31

  Project: Research

• Noncanonical activation of receptor tyrosine kinases: next target mechanisms for cancer progression

  Sakurai, H. (PI), Ozawa, T. (CoI) & Kawasaki, Y. (CoI)

  2016/04/01 → 2019/03/31

  Project: Research

• Structural Study of basal transcription factor TFIIE

  Obita, T. (PI)

  2016/04/01 → 2019/03/31

  Project: Research

• Aggregation of amyloid-beta protein on size-controlled lipid nanoparticles

  Ikeda, K. (PI)

  2016/04/01 → 2018/03/31

  Project: Research

• Mode-of-action analysis of Kampo formulae and prediction of their new indications for a wide range of diseases

  Kadowaki, M. (PI), Shibahara, N. (CoI), Tohda, C. (CoI), Hayashi, S. (CoI), Yamanishi, Y. (CoI), Yamamoto, T. (CoI) & Umezaki, M. (CoI)

  2016/04/01 → 2019/03/31

  Project: Research

• Development of a TTR amyloidogenesis inhibitor based on the capture of transthyretin monomers

  Yokoyama, T. (PI)

  2016/04/01 → 2019/03/31

  Project: Research

• Application of chronotherapy to decrease the drug-induced peripheral neuropathy

  To, H. (PI)

  2016/04/01 → 2019/03/31

  Project: Research

• Molecular mechanisms of transport function at the BBB in epilepsy for normalizing cerebral PGE2 level

  Akanuma, S.-I. (PI), Hosoya, K.-I. (CoI), Kubo, Y. (CoI) & Tachikawa, M. (CoI)

  2016/04/01 → 2019/03/31

  Project: Research

• 高性能光ラベル法による脂質標的分子の同定および結合解析

  Tomohiro, T. (PI)

  2016/04/01 → 2018/03/31

  Project: Research

• Evaluation of Cx43 proteins for PGE2 release from retinal pigment epithelial cells for understanding the pathological role in age-related macular degeneration.

  Hosoya, K.-I. (PI), Kubo, Y. (CoI), Sakai, H. (CoI) & Tachikawa, M. (CoPI)

  2016/04/01 → 2018/03/31

  Project: Research

• Development of Novel Synthetic Methods of Fused-heterocyclic Systems by Domino-type Cycloaddition of o-Xylylene Intermediate

  Matsuya, Y. (PI), Kohyama, A. A. (CoPI) & Koresawa, E. (CoPI)

  2016/04/01 → 2018/03/31

  Project: Research

• Development of environmentally benign metal carbenoid reactions: For catalysts, asymmetric reactions, natural products synthesis

  Yakura, T. (PI)

  2016/04/01 → 2019/03/31

  Project: Research

• Role of CD206 Positive Macrophages in the Intestinal Homeostasis and Inflammatory Bowel Disease

  Hayashi, S. (PI)

  2015/04/01 → 2018/03/31

  Project: Research

• Analysis of multi-components of Wakan-yaku based on chemometric profiling

  Toume, K. (PI), Komatsu, K. (CoI) & Ohtsuki, T. (CoI)

  2015/04/01 → 2019/03/31

  Project: Research

• Comprehensive studies for the biotechnological production of daurichromenic acid, an anti-HIV natural product

  Taura, F. (PI), Akashi, T. (CoPI) & Morita, H. (CoPI)

  2015/04/01 → 2018/03/31

  Project: Research

• ゲルマニウム―アセチレンからなる拡張共役環状元素ブロック高分子の創出

  Tanimoto, H. (PI)

  2015/04/01 → 2017/03/31

  Project: Research

• Collection of new natural sources and analysis of their chemical constituents and construction of genetic resource bank

  Morita, H. (PI), 伊藤卓也. (CoI) & Wong, C. P. (CoI)

  2015/04/01 → 2019/03/31

  Project: Research

• Strategy for designing selective rhamnosidase inhibitors: Synthesis and biological evaluation of L-DMDP cyclic isothioureas

  Adachi, I. (PI), Kato, A. (CoI) & Natori, Y. (CoI)

  2015/04/01 → 2018/03/31

  Project: Research

• Study on medicinal plants in Asia for sustainable use of traditional medicines

  Komatsu, K. (PI), Toume, K. (CoI), Tohda, C. (CoI), Andoh, T. (CoI), Cai, S. Q. (CoI), He, Y. M. (CoI), Javzan, B. (CoI) & Myint, Y. Y. (CoI)

  2015/04/01 → 2018/03/31

  Project: Research

• 消化器癌に対する抗腫瘍和漢薬の確立および臨床応用に関する研究

  Tsukada, K. (PI), Ohnaga, T. (CoI), Morita, H. (CoI) & Nagata, T. (CoI)

  2015/04/01 → 2016/03/31

  Project: Research

• Synthetic study of highly strained anti-cancer natural products by way of umpolung strategy using reactive chemical species

  Tanimoto, H. (PI)

  2015/04/01 → 2018/03/31

  Project: Research

• Investigation of pathogenic mechanisms and Kampo medicine-based preventive and therapeutic strategy for ADHD using an epigenetic animal model.

  Matsumoto, K. (PI), Awale, S. (CoI), 藤原, 博典 (CoI) & Hori, E. (CoI)

  2015/04/01 → 2018/03/31

  Project: Research

• Research on diarrhea-improving effect of Goreisan via the expression of aquaporins in intestine

  Shibahara, N. (PI), Kimura, M. (CoI), Wu, Y. (CoI) & Qiqige, S. (CoI)

  2015/04/01 → 2018/03/31

  Project: Research

• Elucidation of the molecular mechanism producing diterpenes with various tetracyclic skeletons in plant cells

  Yamamura, Y. (PI) & Lee, J. (CoI)

  2015/04/01 → 2018/03/31

  Project: Research

• Elucidation of the molecular components and regulatory mechanism of anion channels controlling the cell homeostasis and death

  Sakai, H. (PI) & Shimizu, T. (CoI)

  2015/04/01 → 2017/03/31

  Project: Research

• Elucidation of mechanism of itch transmission to spinal cord using in vivo patch clamp and three-dimensional electron microscope.

  Uta, D. (PI), Sakamoto, H. (CoI) & Kiguchi, N. (CoI)

  2015/04/01 → 2019/03/31

  Project: Research

• Protective effects of Shati/Nat8l on the dysfunction induced by addictive drugs

  Nitta, A. (PI), Muramatsu, S. I. (CoI) & Uno, K. (CoI)

  2015/04/01 → 2018/03/31

  Project: Research

• Regulation of inflammatory cytokine signaling by TRAF5

  So, T. (PI)

  2015/04/01 → 2018/03/31

  Project: Research

• Development of therapeutic strategy against obesity-associated chronic inflammations based on the mechanism involved in sex-specific difference of Treg localization in adipose tissue.

  Wada, T. (PI), Sasaoka, T. (CoI), Saito, S. (CoI), Sasahara, M. (CoI), Sameshima, A. (CoI), Ishikawa, A. (CoI), Ito, T. (CoI), Ikurumi, M. (CoI) & Tanaka, T. (CoI)

  2015/04/01 → 2018/03/31

  Project: Research

• Mechanisms of the pharmacokinetic variability and optimization of drug therapy in children with congenital heart disease

  Taguchi, M. (PI), Ichida, F. (CoI) & Hirono, K. (CoI)

  2015/04/01 → 2018/03/31

  Project: Research

• Functional and structural analyses of organic cation transporter in the intestine.

  Hashimoto, Y. (PI)

  2015/04/01 → 2018/03/31

  Project: Research

• A new mice model of bipolar disease for the drug developments

  Nitta, A. (PI), Muramatsu, S. I. (CoI), Uno, K. (CoI) & Miyamoto, Y. (CoI)

  2015/04/01 → 2017/03/31

  Project: Research

• Elucidation of the splicing regulatory function of an intrinsically disordered protein PQBP1

  Mizuguchi, M. (PI) & Obita, T. (CoI)

  2015/04/01 → 2018/03/31

  Project: Research

• Studies on novel insulin-sensitizing agent based on SHIP2 inhibitors

  Toyooka, N. (PI), Sasaoka, T. (CoI), Wada, T. (CoI) & Goda, H. H. (CoI)

  2015/04/01 → 2018/03/31

  Project: Research

• Radiosensitization based on intracellular redox control in cancer stem cells

  Kondo, T. (PI), Tabuchi, Y. (CoI), Matsuya, Y. (CoI), Ogawa, R. (PI) & Cho, K. (CoI)

  2015/04/01 → 2018/03/31

  Project: Research

• Impact of the cooperative effect of estrogen and orexin on abnormalities with emotion and metabolism in menopausal mice

  Sasaoka, T. (PI), Wada, T. (CoI) & Tsuneki, H. (CoI)

  2015/04/01 → 2017/03/31

  Project: Research