Faculty of Pharmaceutical Sciences

Projects

Projects per year 1996 2012 2013 2014 2015 2016 2018 2019 2020 2021 2022 2023 2024 2025 2029

• 80 Active
• 304 Finished

Projects per year

Search results

• Finished

  Determining factors for giving structural diversity and analysis of temporospatial dynamics of onjisaponins

  Lee, J. (PI), Yamamura, Y. (CoI), Yamagaki, T. (CoI), Tatsuo, Y. (CoI), Takao, Y. (CoI) & Murakami, Y. (CoI)

  2015/04/01 → 2018/03/31

  Project: Research

• Transcriptional regulatory mechanism of the RNA polymerase II initiation complex by the chromatin remodeling complex

  Tanaka, A. (PI)

  2015/04/01 → 2018/03/31

  Project: Research

• Significance of homeodynamic regulation by hypothalamic orexin in preventing obesity and type 2 diabetes

  Tsuneki, H. (PI) & Sasaoka, T. (CoI)

  2015/04/01 → 2018/03/31

  Project: Research

• Identification of Scientific evidence for Traditional Kampo theory by gene expression analysis

  Saiki, I. (PI) & Yokoyama, S. (CoI)

  2015/04/01 → 2018/03/31

  Project: Research

• Structural analysis of membrane protein based on multi-labeled sites

  Tomohiro, T. (PI), Chiba, J. (CoI), Shimizu, T. (CoI) & Matsunaga, S. (CoI)

  2015/04/01 → 2018/03/31

  Project: Research

• Synthetic studies on natural products containing highly substituted heterocyclic skeletons using ring-opening cyclization of spirocyclopropanes

  Nambu, H. (Principal Investigator)

  Japan Society for the Promotion of Science

  2015/04/01 → 2018/03/31

  Project: Research Project

• ＦｔｓＺ阻害活性を基盤としたベトナム産植物中の抗生物質に関する研究

  Morita, H. (PI) & Nguyen, H. T. (CoI)

  2014/04/25 → 2017/03/31

  Project: Research

• がん悪性化に関わる炎症を制御する生理活性物質の探索

  Banbury, L. L. (PI) & Hayakawa, Y. (CoI)

  2014/04/25 → 2015/03/31

  Project: Research

• Synthetic studies toward (+)-CJ-12,950 for the stereochemical elucidation and structure activity relationship studies

  Sugimoto, K. (PI)

  2014/04/01 → 2017/03/31

  Project: Research

• Role of pregnane X receptor in the preventive effect of Boiogito against experimentally induced cholestatic liver injury

  Watanabe, S. (PI)

  2014/04/01 → 2017/03/31

  Project: Research

• Control of cell differentiation by ultrasound through epigenetic mechanisms

  Tabuchi, Y. (PI)

  2014/04/01 → 2017/03/31

  Project: Research

• Engineering of plant-specific polyketide scaffold synthetic enzymes to produce structural diversity of compounds

  Morita, H. (PI), Matsui, T. (CoI) & Kodama, T. (CoI)

  2014/04/01 → 2017/03/31

  Project: Research

• Engineering of type III polyketide synthase by deletion and addition of residues

  Morita, H. (PI)

  2014/04/01 → 2016/03/31

  Project: Research

• Design and synthesis of iminosugar-based pharmacological chaperone as a structure stabilizing agent for mutation enzyme

  Kato, A. (PI)

  2014/04/01 → 2017/03/31

  Project: Research

• Traditional medicine-based drug development-creation of new paradigm-

  Tohda, C. (PI), Kazuma, K. (CoI) & Konno, K. (CoI)

  2014/04/01 → 2017/03/31

  Project: Research

• Elucidation of dynamic control of biomembrane functions by phospholipid transfer proteins

  Nakano, M. (PI) & Ikeda, K. (CoI)

  2014/04/01 → 2017/03/31

  Project: Research

• Structural basis of Archaeal ESCRT complex

  Obita, T. (PI)

  2014/04/01 → 2016/03/31

  Project: Research

• Study of cationic drug efflux across the blood-retinal barrier

  Kubo, Y. (PI), Akanuma, S.-I. (CoI), Hosoya, K.-I. (CoI) & Nishi, T. (CoI)

  2014/04/01 → 2017/03/31

  Project: Research

• ルイス塩基触媒と分子内ケイ素移動とを融合させた新規有機触媒反応システムの開発

  Matsuya, Y. (PI)

  2014/04/01 → 2016/03/31

  Project: Research

• Structure and molecular interactions in aggregation of amyloid beta protein

  Ikeda, K. (PI)

  2014/04/01 → 2016/03/31

  Project: Research

• Regulation of Arc gene transcription by SRF cofactors: mechanism and application for drug design in ASD

  Tabuchi, A. (PI), Mori, H. (CoI) & Fukuchi, M. (CoI)

  2014/04/01 → 2017/03/31

  Project: Research

• Novel anti-cancer mechanism of the targeting of the association between receptor-type sodium pump and VSOR channels

  Fujii, T. (PI)

  2014/04/01 → 2017/03/31

  Project: Research

• Exploration of tumor-promoting inflammatory immune responses and its application for cancer treatment

  Hayakawa, Y. (PI)

  2014/04/01 → 2017/03/31

  Project: Research

• ABC protein subfamily D: Mechanisms about subcellular localization and substrate transport, and regulation of cell function

  今中常雄 (Principal Investigator) & Kawaguchi, K. (Co-Investigator(Kenkyū-buntansha))

  Japan Society for the Promotion of Science

  2014/04/01 → 2017/03/31

  Project: Research Project

• Explore molecular basis underlying formation of chemical diversity in genus Panax through RNA-Seq analysis of three Panax species with different chemical compositions

  Zhu, S. (Principal Investigator)

  Japan Society for the Promotion of Science

  2014/04/01 → 2017/03/31

  Project: Research Project

• Natural Products Chemical Biology targeting Wnt signaling pathway modulation

  Toume, K. (PI)

  2013/04/01 → 2015/03/31

  Project: Research

• Anti-allergic effect of kakkonto by regulating intestinal mucosal immunity through the induction of regulatory T cells in the colon

  Yamamoto, T. (PI) & Hayashi, S. (CoI)

  2013/04/01 → 2016/03/31

  Project: Research

• インドールプレニル基転移酵素の動的立体構造基盤の確立と酵素触媒機能の拡張

  Morita, H. (PI)

  2013/04/01 → 2015/03/31

  Project: Research

• In vivo patch-clamp analysis of itch transmission in central nerve system

  Uta, D. (PI)

  2013/04/01 → 2015/03/31

  Project: Research

• Investigation of the immunological function of the NASH-inducing transplanted NKT, and drug discovery

  Koizumi, K. (PI)

  2013/04/01 → 2015/03/31

  Project: Research

• Effect of Goreisan on edema improvement mechanism and expression of aquaporin 2.

  Jo, M. (PI)

  2013/04/01 → 2015/03/31

  Project: Research

• Elucidation of the biosynthetic mechanism that leads to the diversity of the tetracyclic skeleton of diterpenes

  Yamamura, Y. (PI)

  2013/04/01 → 2015/03/31

  Project: Research

• エチニルピリジンオリゴマーが構築する超分子構造の観測と応用

  Ohishi, Y. (PI)

  2013/04/01 → 2016/03/31

  Project: Research

• Functional coupling between ion channels and scramblases in human TMEM16F-expressing cells

  Shimizu, T. (PI)

  2013/04/01 → 2016/03/31

  Project: Research

• Clarification of molecular and physiological properties of the acid-preventing barrier in gastric parietal cells

  Sakai, H. (PI), Sawaguchi, A. (CoI) & Ikari, A. (CoI)

  2013/04/01 → 2016/03/31

  Project: Research

• Development of novel anti-virus drugs by means of libraries of sialic acid derivatives possessing an anion at the 1-position

  Chiba, J. (PI), Hatanaka, Y. (CoI) & Tomohiro, T. (CoI)

  2013/04/01 → 2017/03/31

  Project: Research

• Role of estrogen via the recruitment of Treg in the control of glucose homeostasis in female mice.

  Sasaoka, T. (PI), Tsuneki, H. (CoI) & Wada, T. (CoI)

  2013/04/01 → 2015/03/31

  Project: Research

• Creation of reaction field on lipid membrane with phospholipid bilayer nanodiscs

  Nakano, M. (PI)

  2013/04/01 → 2015/03/31

  Project: Research

• Neutron Diffraction Analysis of Human Farnesyl Pyrophosphate Synthase in Complex with Bisphosphonate

  Yokoyama, T. (PI)

  2013/04/01 → 2016/03/31

  Project: Research

• Design, Synthesis, and Structure-Activity Relationship Study of Novel Neuro-Protecting Drugs Based on Natural Product Hybridization

  Matsuya, Y. (PI), Sugimoto, K. (CoI) & Tohda, C. (CoI)

  2013/04/01 → 2016/03/31

  Project: Research

• Effect of obesity and diabetes on liver cancer and tumor-associated macrophage polarization

  Usui, I. (PI), Hayakawa, Y. (CoI) & Tsuneyama, K. (CoI)

  2013/04/01 → 2016/03/31

  Project: Research

• Evaluation of cationic drug transport system at the blood-retinal barrier to deliver the drugs to the retina

  Hosoya, K.-I. (PI), Akanuma, S.-I. (CoI), Kubo, Y. (CoI), Matsuya, Y. (CoI) & Takashima, T. (CoI)

  2013/04/01 → 2016/03/31

  Project: Research

• Search for Therapeutic Drugs Against Ulcerative Colitis-Mechanism Elucidation of Daikenchuto

  Hayashi, S. (PI)

  2012/04/01 → 2014/03/31

  Project: Research

  • Mechanism Elucidation 100%
  • Daikenchuto 100%
  • Therapeutic Agents 100%
  • Ulcerative Colitis 100%
  • Colitis 75%

• cDNA cloning of enzymes responsible for scent compound biosynthesis from rose geranium and their application for molecular breeding

  Taura, F. (PI), Asakawa, Y. (CoI) & Kenmoku, H. (CoI)

  2012/04/01 → 2015/03/31

  Project: Research

• Development of domino cyclization reaction for one-pot synthesis of pyrroloindolizines and its application to total syntheses of related alkaloids

  Sugimoto, K. (PI)

  2012/04/01 → 2014/03/31

  Project: Research

  • Domino Cyclization 100%
  • Alkaloids 100%
  • Cyclization Reaction 100%
  • Enamines 100%
  • Total Synthesis 100%

• Structural basis for plant-specific type III polyketide synthase based on the X-ray crystal structure analysis and computational chemistry

  Morita, H. (PI)

  2012/04/01 → 2014/03/31

  Project: Research

  • Analytical Chemistry Analysis 100%
  • Type III Polyketide Synthase 100%
  • Mutant Enzyme 100%
  • Octaketide Synthase 100%
  • Computational Chemistry 100%

• Search for the antiausterity agents induced metabolomic biomarkers associated with the tolerance of nutrition starvation in pancreatic cancer

  Awale, S. (PI) & Esumi, H. (CoI)

  2012/04/01 → 2016/03/31

  Project: Research

• Verification of relationships between dysfunction of the cell stress-protection system by exposures to multiple environmental chemicals and diseases

  Tabuchi, Y. (PI), Hoshi, N. (CoI) & Kondo, T. (CoI)

  2012/04/01 → 2016/03/31

  Project: Research

• Synthetic Studies on novel fucosidase and rhamnosidase inhibitors

  Toyooka, N. (PI) & Kato, A. (CoI)

  2012/04/01 → 2015/03/31

  Project: Research

• A simple method to evaluate pharmacokinetics in children with a reduced blood sampling and optimization of dosage of cardiovascular drugs.

  Taguchi, M. (PI), Ichida, F. (CoI), Saito, K. (CoI), Hirono, K. (CoI) & Ishida, K. (CoI)

  2012/04/01 → 2015/03/31

  Project: Research