Projects per year
- 1 - 50 out of 384 results
Search results
-
ABCD1機能欠損リンパ球のTh1型反応の亢進が大脳型ALD発症に関与する
Morita, M. (Principal Investigator), So, T. (Co-Investigator(Kenkyū-buntansha)) & Kuniishi, M. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2025/04/01 → 2028/03/31
Project: Research Project
-
AchE阻害活性アルカロイドの骨格生合成酵素の機能解析と改変
Morita, H. (Principal Investigator), Kodama, T. (Co-Investigator(Kenkyū-buntansha)) & Nakashima, Y. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2022/04/01 → 2025/03/31
Project: Research Project
-
-
ABC protein subfamily D: Mechanisms about subcellular localization and substrate transport, and regulation of cell function
今中常雄 (Principal Investigator) & Kawaguchi, K. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2014/04/01 → 2017/03/31
Project: Research Project
-
Adrenoleukodystrophy: effect of bone marrow transplantation in abcd1-deficient mouse
Morita, M. (PI)
2016/04/01 → 2019/03/31
Project: Research
-
Aggregation of amyloid-beta protein on size-controlled lipid nanoparticles
Ikeda, K. (PI)
2016/04/01 → 2018/03/31
Project: Research
-
Alternative activation mechanisms of receptor tyrosine kinases in inflammation-induced cancer progression
Sakurai, H. (PI)
2019/04/01 → 2022/03/31
Project: Research
-
Analyses of essential interactions of iminosugars with the Hex A active site and evaluation of their pharmacological chaperone effects for Tay-Sachs disease
Kato, A. (PI)
2017/04/01 → 2020/03/31
Project: Research
-
Analysing the pathophysiological role of receptor molecules selectively upregulated in bone metastatic breast cancer
Sasaki, S. (Principal Investigator) & 向田直史 (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2020/04/01 → 2023/03/31
Project: Research Project
-
Analysis of Manic Switch Mechanism by Antidepressants in Bipolar Disorder model mice
Yano, Y. (Principal Investigator)
Japan Society for the Promotion of Science
2024/07/31 → 2026/03/31
Project: Research Project
-
Analysis of multi-components of Wakan-yaku based on chemometric profiling
Toume, K. (PI), Komatsu, K. (CoI) & Ohtsuki, T. (CoI)
2015/04/01 → 2019/03/31
Project: Research
-
A new mice model of bipolar disease for the drug developments
Nitta, A. (PI), Muramatsu, S. I. (CoI), Uno, K. (CoI) & Miyamoto, Y. (CoI)
2015/04/01 → 2017/03/31
Project: Research
-
Anti-allergic effect of kakkonto by regulating intestinal mucosal immunity through the induction of regulatory T cells in the colon
Yamamoto, T. (PI) & Hayashi, S. (CoI)
2013/04/01 → 2016/03/31
Project: Research
-
Application of chronotherapy of antirheumatic drug to perform proper therapy
To, H. (PI)
2012/04/01 → 2014/03/31
Project: Research
-
Application of chronotherapy to decrease the drug-induced peripheral neuropathy
To, H. (PI)
2016/04/01 → 2019/03/31
Project: Research
-
A Research of Epithelium-Immune Interaction during Mucosal Repair in Inflammatory Bowel Disease
Hayashi, S. (PI)
2018/04/01 → 2023/01/03
Project: Research
-
A simple method to evaluate pharmacokinetics in children with a reduced blood sampling and optimization of dosage of cardiovascular drugs.
Taguchi, M. (PI), Ichida, F. (CoI), Saito, K. (CoI), Hirono, K. (CoI) & Ishida, K. (CoI)
2012/04/01 → 2015/03/31
Project: Research
-
Asymmetric syntheses of biologically active heterocyclic natural products employing catalytic C-H activation strategy
Nambu, H. (Principal Investigator)
Japan Society for the Promotion of Science
2012/04/01 → 2015/03/31
Project: Research Project
-
cDNA cloning of enzymes responsible for scent compound biosynthesis from rose geranium and their application for molecular breeding
Taura, F. (PI), Asakawa, Y. (CoI) & Kenmoku, H. (CoI)
2012/04/01 → 2015/03/31
Project: Research
-
Central role of orexin in the regulation of insulin-mediated glucose metabolism
Tsuneki, H. (PI) & Sasaoka, T. (CoI)
2007/04/01 → 2009/03/31
Project: Research
-
Characterization of multifunctional roles of TRAF5 in pro-inflammatory cytokine receptor signaling
So, T. (PI)
2018/04/01 → 2021/03/31
Project: Research
-
Clarification of molecular and physiological properties of the acid-preventing barrier in gastric parietal cells
Sakai, H. (PI), Sawaguchi, A. (CoI) & Ikari, A. (CoI)
2013/04/01 → 2016/03/31
Project: Research
-
Clarification of the mechanism by which the impairment of intra-hepatic cellular network caused hepatic insulin resistance in mice.
Wada, T. (PI)
2008/04/01 → 2010/03/31
Project: Research
-
Clarification of the mechanism of estrogen-induced regulation of insulin sensitivity in the pathogenesis of type 2 diabetes in female
Sasaoka, T. (PI)
2005/04/01 → 2007/03/31
Project: Research
-
Clinical pharmacokinetic trials in pediatric patients based on a peak-and-trough sampling design
Taguchi, M. (PI)
2010/04/01 → 2012/03/31
Project: Research
-
Collection of new natural sources and analysis of their chemical constituents and construction of genetic resource bank
Morita, H. (PI), 伊藤卓也. (CoI) & Wong, C. P. (CoI)
2015/04/01 → 2019/03/31
Project: Research
-
Comprehensive elucidation of the biosynthetic pathway of arzanol to establish its microbial production platform
Taura, F. (PI)
2018/04/01 → 2021/03/31
Project: Research
-
Comprehensive studies for the biotechnological production of daurichromenic acid, an anti-HIV natural product
Taura, F. (PI), Akashi, T. (CoPI) & Morita, H. (CoPI)
2015/04/01 → 2018/03/31
Project: Research
-
Comprehensive study on diversity of Curcuma drugs used as medicines / food supplements for standardization, responding to a global society
Komatsu, K. (Principal Investigator), Toume, K. (Co-Investigator(Kenkyū-buntansha)) & ZHU, S. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2018/04/01 → 2021/03/31
Project: Research Project
-
Comprehensive understanding of the phospholipid flip mechanism in the endoplasmic reticulum and establishment of the control technology of biomembrane dynamics
Nakano, M. (PI) & Ikeda, K. (CoI)
2017/04/01 → 2021/03/31
Project: Research
-
Construction of a program for sustainable use of traditional medicines, based on integrated study of genetic, chemical and pharmacological diversity of medicinal plants
Komatsu, K. (PI), Tohda, C. (CoI), Kadowaki, M. (CoI), Zhu, S. (CoI) & Kazuma, K. (CoI)
2012/04/01 → 2015/03/31
Project: Research
-
Control of cell differentiation and proliferation by ultrasound: elucidation of the role of epigenome
Tabuchi, Y. (PI) & Hasegawa, H. (CoI)
2017/04/01 → 2020/03/31
Project: Research
-
Control of cell differentiation by ultrasound through epigenetic mechanisms
Tabuchi, Y. (PI)
2014/04/01 → 2017/03/31
Project: Research
-
Creation of New Therapeutic Strategy for Inflammatory Bowel Disease Aiming to Prevent Relapse Based on Rebuilding Mucosal Barrier
Hayashi, S. (PI)
2021/04/01 → 2024/03/31
Project: Research
-
Creation of reaction field on lipid membrane with phospholipid bilayer nanodiscs
Nakano, M. (PI)
2013/04/01 → 2015/03/31
Project: Research
-
Daily rhythmic regulation of glucose metabolism by hypothalamic orexin system: a chronotherapeutic target for type 2 diabetes
Tsuneki, H. (PI) & Sasaoka, T. (CoI)
2012/04/01 → 2015/03/31
Project: Research
-
Design, synthesis, and biological evaluation of iminosugars as pharmacological chaperone for Gaucher disease
Kato, A. (PI), Takahata, H. (CoPI), Hirono, S. (CoPI), Ishii, S. (CoPI) & Adachi, I. (CoPI)
2011/04/01 → 2014/03/31
Project: Research
-
Design, Synthesis, and Structure-Activity Relationship Study of Novel Neuro-Protecting Drugs Based on Natural Product Hybridization
Matsuya, Y. (PI), Sugimoto, K. (CoI) & Tohda, C. (CoI)
2013/04/01 → 2016/03/31
Project: Research
-
Design and synthesis of iminosugar-based pharmacological chaperone as a structure stabilizing agent for mutation enzyme
Kato, A. (PI)
2014/04/01 → 2017/03/31
Project: Research
-
Detection of novel actions of kampo medicines for lipid metabolism by lipidomic analysis
Watanabe, S. (PI) & Tsuneyama, K. (CoI)
2011/04/01 → 2014/03/31
Project: Research
-
Determining factors for giving structural diversity and analysis of temporospatial dynamics of onjisaponins
Lee, J. (PI), Yamamura, Y. (CoI), Yamagaki, T. (CoI), Tatsuo, Y. (CoI), Takao, Y. (CoI) & Murakami, Y. (CoI)
2015/04/01 → 2018/03/31
Project: Research
-
Development and application of multi-functional hybrid-type organocatalysts based on hypervalent iodine oxidation
Yakura, T. (PI)
2009/04/01 → 2012/03/31
Project: Research
-
Development and application of versatile asymmetric Nazarov cyclization with novel biphenol-boric acid catalyst system
Sugimoto, K. (PI)
2020/04/01 → 2023/03/31
Project: Research
-
Development and biological application of sulfo-click type reactions
Hatanaka, Y. (PI) & Chiba, J. (CoI)
2011/04/01 → 2014/03/31
Project: Research
-
Development and biological application of thioamide-click type reactions
Chiba, J. (PI)
2017/04/01 → 2020/03/31
Project: Research
-
Development of a method for activation of costimulatory immune receptors by using their corresponding multimerized ligands
So, T. (Principal Investigator) & 石井直人 (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2023/06/30 → 2025/03/31
Project: Research Project
-
Development of a new pancreatic cancer curative medicine from arctigenin, an ingredient of Wakan-yaku 'Burdock Fruit (Seeds of Arctium lappa)'
Tezuka, Y. (PI), Toyooka, N. (CoI) & Awale, S. (CoI)
2010/04/01 → 2013/03/31
Project: Research
-
Development of a new therapeutics of gestational diabetes by inhibition of the central action of lipid phosphatase
Sasaoka, T. (PI), Tsuneki, H. (CoI) & Wada, T. (CoI)
2011/04/01 → 2013/03/31
Project: Research
-
Development of a novel anti-cancer immunotherapy based on tumor immunogenicity improvement by abnormal self-antigens
Susukida, T. (PI)
2020/09/11 → 2022/03/31
Project: Research
-
Development of a novel treatment based on the circadian rhythm unique to atopic dermatitis
To, H. (Principal Investigator)
Japan Society for the Promotion of Science
2025/04/01 → 2028/03/31
Project: Research Project