Yoshiya Ikawa

2025

Biochemical Characterization of a Non-G4-Type RNA Aptamer That Lights Up a GFP-like Fluorogenic Ligand

Abe, S., Aburaya, S., Koyama, T., Usui, T., Yoshino, J., Matsumura, S. & Ikawa, Y., 2025/04, In: Molecules. 30, 8, 1777.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

2024

Catalytic cleavage of an RNA substrate that bypasses the reorganization of its secondary structure during substrate recognition by a trans-acting VS ribozyme

Miyazaki, Y., Nakane, R., Tanishi, S., Matsumura, S. & Ikawa, Y., 2024, (印刷前の電子出版) In: Nucleosides, Nucleotides and Nucleic Acids.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

2022

A Hexameric Ribozyme Nanostructure Formed by Double-Decker Assembly of a Pair of Triangular Ribozyme Trimers

Yu, K., Hidaka, K., Sugiyama, H., Endo, M., Matsumura, S. & Ikawa, Y., 2022/03/18, In: ChemBioChem. 23, 6, e202100573.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

3 被引用数 (Scopus)

2021

Flexible Assembly of Engineered Tetrahymena Ribozymes Forming Polygonal RNA Nanostructures with Catalytic Ability

Mori, Y., Oi, H., Suzuki, Y., Hidaka, K., Sugiyama, H., Endo, M., Matsumura, S. & Ikawa, Y., 2021/06/15, In: ChemBioChem. 22, 12, p. 2168-2176 9 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

5 被引用数 (Scopus)

2018

Biogenic triamine and tetraamine activate core catalytic ability of Tetrahymena group I ribozyme in the absence of its large activator module

Gulshan, M. A., Rahman, M. M., Matsumura, S., Higuchi, T., Umezawa, N. & Ikawa, Y., 2018/02/05, In: Biochemical and Biophysical Research Communications. 496, 2, p. 594-600 7 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

8 被引用数 (Scopus)

Comparative study of polyethylene polyamines as activator molecules for a structurally unstable group I ribozyme

Gulshan, A., Matsumura, S., Higuchi, T., Umezawa, N. & Ikawa, Y., 2018, In: Bioscience, biotechnology, and biochemistry. 82, 8, p. 1404-1407 4 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

1 被引用数 (Scopus)

Engineered group i ribozymes as RNA-based modular tools to control gene expression

Ikawa, Y. & Matsumura, S., 2018/04/10, Applied RNA Bioscience. Springer Singapore, p. 203-220 18 p.

研究成果: 書籍の章/レポート/会議録 › 章 › 査読

3 被引用数 (Scopus)

Recognition of cyclic-di-GMP by a riboswitch conducts translational repression through masking the ribosome-binding site distant from the aptamer domain

Inuzuka, S., Kakizawa, H., Nishimura, K. I., Naito, T., Miyazaki, K., Furuta, H., Matsumura, S. & Ikawa, Y., 2018/06, In: Genes to Cells. 23, 6, p. 435-447 13 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

12 被引用数 (Scopus)

2017

Artificial rna motifs expand the programmable assembly between RNA modules of a bimolecular ribozyme leading to application to RNA nanostructure design

Rahman, M. M., Matsumura, S. & Ikawa, Y., 2017/12, In: Biology. 6, 4, 37.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

9 被引用数 (Scopus)

Heterodimerization of Group I Ribozymes Enabling Exon Recombination through Pairs of Cooperative trans-Splicing Reactions

Tanaka, T., Hirata, Y., Tominaga, Y., Furuta, H., Matsumura, S. & Ikawa, Y., 2017/08/17, In: ChemBioChem. 18, 16, p. 1659-1667 9 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

9 被引用数 (Scopus)

Programmable formation of catalytic RNA triangles and squares by assembling modular RNA enzymes

Oi, H., Fujita, D., Suzuki, Y., Sugiyama, H., Endo, M., Matsumura, S. & Ikawa, Y., 2017/05/01, In: Journal of Biochemistry. 161, 5, p. 451-462 12 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

21 被引用数 (Scopus)

Rational engineering of a modular group I ribozyme to control its activity by self-dimerization

Tanaka, T., Ikawa, Y. & Matsumura, S., 2017, In: Methods in Molecular Biology. p. 325-340 16 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

4 被引用数 (Scopus)

2016

Characterization of an RNA receptor motif that recognizes a gcga tetraloop

Furukawa, A., Maejima, T., Matsumura, S. & Ikawa, Y., 2016, In: Bioscience, biotechnology, and biochemistry. 80, 7, p. 1386-1389 4 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

6 被引用数 (Scopus)

Mutational analysis of structural elements in a class-I cyclic di-GMP riboswitch to elucidate its regulatory mechanism

Inuzuka, S., Nishimura, K. I., Kakizawa, H., Fujita, Y., Furuta, H., Matsumura, S. & Ikawa, Y., 2016/09/01, In: Journal of Biochemistry. 160, 3, p. 153-162 10 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

11 被引用数 (Scopus)

Optimization of RNA-based c-di-GMP fluorescent sensors through tuning their structural modules

Inuzuka, S., Matsumura, S. & Ikawa, Y., 2016/08/01, In: Journal of Bioscience and Bioengineering. 122, 2, p. 183-187 5 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

5 被引用数 (Scopus)

Prototheca miyajii sp. nov., isolated from a patient with systemic protothecosis

Masuda, M., Hirose, N., Ishikawa, T., Ikawa, Y. & Nishimura, K., 2016/03, In: International Journal of Systematic and Evolutionary Microbiology. 66, 3, p. 1510-1520 11 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

47 被引用数 (Scopus)

Tecto-GIRz: Engineered Group I Ribozyme the Catalytic Ability of Which Can Be Controlled by Self-Dimerization

Tanaka, T., Matsumura, S., Furuta, H. & Ikawa, Y., 2016/08/03, In: ChemBioChem. p. 1448-1455 8 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

15 被引用数 (Scopus)

Use of a fluorescent aptamer RNA as an exonic sequence to analyze self-splicing ability of a group i intron from structured RNAs

Furukawa, A., Tanaka, T., Furuta, H., Matsumura, S. & Ikawa, Y., 2016/12/01, In: Biology. 5, 4, 43.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

4 被引用数 (Scopus)

2015

Artificial ligase ribozymes isolated by a “design and selection” strategy

Matsumura, S. & Ikawa, Y., 2015/05/16, In: Methods in molecular biology (Clifton, N.J.). 1316, p. 113-125 13 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Modulation of group I ribozyme activity by cationic porphyrins

Matsumura, S., Ito, T., Tanaka, T., Furuta, H. & Ikawa, Y., 2015/03/24, In: Biology. 4, 2, p. 251-263 13 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

3 被引用数 (Scopus)

2014

Installation of orthogonality to the interface that assembles two modular domains in the Tetrahymena group I ribozyme

Tanaka, T., Furuta, H. & Ikawa, Y., 2014/04, In: Journal of Bioscience and Bioengineering. 117, 4, p. 407-412 6 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

12 被引用数 (Scopus)

Multiple genome modifications by the CRISPR/Cas9 system in zebrafish

Ota, S., Hisano, Y., Ikawa, Y. & Kawahara, A., 2014/07, In: Genes to Cells. 19, 7, p. 555-564 10 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

99 被引用数 (Scopus)

2013

An in vitro-selected RNA receptor for the GAAC loop: Modular receptor for non-GNRA-type tetraloop

Ishikawa, J., Furuta, H. & Ikawa, Y., 2013/04, In: Nucleic Acids Research. 41, 6, p. 3748-3759 12 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

10 被引用数 (Scopus)

Colorimetric/fluorogenic detection of thiols by N-fused porphyrin in water

Ikawa, Y., Touden, S., Katsumata, S. & Furuta, H., 2013/11/01, In: Bioorganic and Medicinal Chemistry. 21, 21, p. 6501-6505 5 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

13 被引用数 (Scopus)

Fixation and accumulation of thermotolerant catalytic competence of a pair of ligase ribozymes through complex formation and cross ligation

Isomoto, N., Maeda, Y., Tanaka, T., Furuta, H. & Ikawa, Y., 2013/02, In: Journal of Molecular Evolution. 76, 1-2, p. 48-58 11 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

4 被引用数 (Scopus)

RNA Tectonics (tectoRNA) for RNA nanostructure design and its application in synthetic biology

Ishikawa, J., Furuta, H. & Ikawa, Y., 2013/11, In: Wiley Interdisciplinary Reviews: RNA. 4, 6, p. 651-664 14 p.

研究成果: ジャーナルへの寄稿 › 総説 › 査読

45 被引用数 (Scopus)

2012

A two-piece derivative of a group i intron RNA as a platform for designing self-assembling RNA templates to promote peptide ligation

Tanaka, T., Furuta, H. & Ikawa, Y., 2012, In: Journal of Nucleic Acids. 2012, 305867.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

1 被引用数 (Scopus)

Deprotonation-induced aromaticity enhancement and new conjugated networks in meso-hexakis(pentafluorophenyl)[26]hexaphyrin

Cha, W. Y., Lim, J. M., Yoon, M. C., Sung, Y. M., Lee, B. S., Katsumata, S., Suzuki, M., Mori, H., Ikawa, Y., Furuta, H., Osuka, A. & Kim, D., 2012/12/03, In: Chemistry - A European Journal. 18, 49, p. 15838-15844 7 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

28 被引用数 (Scopus)

Functional roles of a tetraloop/receptor interacting module in a cyclic di-GMP riboswitch

Fujita, Y., Tanaka, T., Furuta, H. & Ikawa, Y., 2012/02, In: Journal of Bioscience and Bioengineering. 113, 2, p. 141-145 5 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

17 被引用数 (Scopus)

Sulfur-assisted interconversion between N-confused porphyrin and N-fused porphyrin

Touden, S., Ikawa, Y., Sakashita, R., Toganoh, M., Mori, S. & Furuta, H., 2012/11/07, In: Tetrahedron Letters. 53, 45, p. 6071-6074 4 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

14 被引用数 (Scopus)

TectoRNP: Self-assembling RNAs with peptide recognition motifs as templates for chemical peptide ligation

Yamashita, K., Tanaka, T., Furuta, H. & Ikawa, Y., 2012/10, In: Journal of Peptide Science. 18, 10, p. 635-642 8 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

2 被引用数 (Scopus)

2011

N-fused porphyrin with pyridinium side-arms: A new class of aromatic ligand with DNA-binding ability

Ikawa, Y., Touden, S. & Furuta, H., 2011/12/07, In: Organic and Biomolecular Chemistry. 9, 23, p. 8068-8078 11 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

14 被引用数 (Scopus)

Turnover ability of a designed RNA acting as a template for chemical peptide ligation

Yamashita, K., Kashiwagi, N., Furuta, H. & Ikawa, Y., 2011, In: Bioscience, biotechnology, and biochemistry. 75, 10, p. 2021-2024 4 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

4 被引用数 (Scopus)

2010

Generation and development of RNA ligase ribozymes with modular architecture through "design and selection"

Fujita, Y., Ishikawa, J., Furuta, H. & Ikawa, Y., 2010/09, In: Molecules. 15, 9, p. 5850-5865 16 p.

研究成果: ジャーナルへの寄稿 › 総説 › 査読

Open Access

9 被引用数 (Scopus)

2009

Coordinated control of a designed trans-acting ligase ribozyme by a loop-receptor interaction

Matsumura, S., Ohmori, R., Saito, H., Ikawa, Y. & Inoue, T., 2009/09/03, In: FEBS Letters. 583, 17, p. 2819-2826 8 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

20 被引用数 (Scopus)

Designed RNAs with two peptide-binding units as artificial templates for native chemical ligation of RNA-binding peptides

Kashiwagi, N., Yamashita, K., Furuta, H. & Ikawa, Y., 2009/11/23, In: ChemBioChem. 10, 17, p. 2745-2752 8 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

9 被引用数 (Scopus)

Synthesis and protonation behavior of a water-soluble N-fused porphyrin: Conjugation with an oligoarginine by click chemistry

Ikawa, Y., Harada, H., Toganoh, M. & Furuta, H., 2009/05/01, In: Bioorganic and Medicinal Chemistry Letters. 19, 9, p. 2448-2452 5 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

27 被引用数 (Scopus)

2008

Facile syntheses of BODIPY derivatives for fluorescent labeling of the 3′ and 5′ ends of RNAs

Ikawa, Y., Moriyama, S. & Furuta, H., 2008/07/15, In: Analytical Biochemistry. 378, 2, p. 166-170 5 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

49 被引用数 (Scopus)

N-confused porphyrin possessing glucamine-appendants: Aggregation and acid/base properties in aqueous media

Ikawa, Y., Ogawa, H., Harada, H. & Furuta, H., 2008/12/15, In: Bioorganic and Medicinal Chemistry Letters. 18, 24, p. 6394-6397 4 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

25 被引用数 (Scopus)

2007

Design and analysis of a structural RNA that acts as a template for peptide ligation.

Kashiwagi, N., Furuta, H. & Ikawa, Y., 2007, In: Nucleic acids symposium series (2004). 51, p. 387-388 2 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

3 被引用数 (Scopus)

2002

Mispaired P3 region in the hierarchical folding pathway of the Tetrahymena ribozyme

Ohki, Y., Ikawa, Y., Shiraishi, H. & Inoue, T., 2002/08, In: Genes to Cells. 7, 8, p. 851-860 10 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

4 被引用数 (Scopus)

Two conserved structural components, A-rich bulge and P4 XJ6/7 base-triples, in activating the group I ribozymes

Ikawa, Y., Yoshimura, T., Hara, H., Shiraishi, H. & Inoue, T., 2002/12/01, In: Genes to Cells. 7, 12, p. 1205-1215 11 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

11 被引用数 (Scopus)

2001

A deteriorated triple-helical scaffold accelerates formation of the Tetrahymena ribozyme active structure

Ohki, Y., Ikawa, Y., Shiraishi, H. & Inoue, T., 2001/03/30, In: FEBS Letters. 493, 2-3, p. 95-100 6 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

5 被引用数 (Scopus)

Self-splicing of the Tetrahymena group I ribozyme without conserved base-triples

Ikawa, Y., Yoshioka, W., Ohki, Y., Shiraishi, H. & Inoue, T., 2001, In: Genes to Cells. 6, 5, p. 411-420 10 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

12 被引用数 (Scopus)

1996

Characterization of the newly constructed domains that replace P5abc within the Tetrahymena ribozyme

Ikawa, Y., Shiraishi, H. & Inoue, T., 1996/09/23, In: FEBS Letters. 394, 1, p. 5-8 4 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

8 被引用数 (Scopus)

井川 善也

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井川善也