Faculty of Pharmaceutical Sciences

Projects

Projects per year 1996 2012 2013 2014 2015 2016 2018 2019 2020 2021 2022 2023 2024 2025 2029

• 80 Active
• 304 Finished

Projects per year

Search results

• Finished

  基本転写因子によるRNAポリメラーゼIIの構造変換の分子機構の解析

  Tanaka, A. (PI)

  2018/04/01 → 2022/03/31

  Project: Research

• Characterization of multifunctional roles of TRAF5 in pro-inflammatory cytokine receptor signaling

  So, T. (PI)

  2018/04/01 → 2021/03/31

  Project: Research

• 小児発達の個体差を考慮した症例追跡に基づく薬物動態解析と長期投与の適正化支援

  Taguchi, M. (PI)

  2018/04/01 → 2022/03/31

  Project: Research

• メロテルペノイド高酸化型骨格に着目した化合物ライブラリー構築と抗癌剤創薬への展開

  Matsuya, Y. (PI)

  2018/04/01 → 2021/03/31

  Project: Research

• 精神疾患・発達障害リスク転写因子MKLによるシナプスから核への情報伝達機構解明

  Tabuchi, A. (PI)

  2018/04/01 → 2021/03/31

  Project: Research

• Comprehensive study on diversity of Curcuma drugs used as medicines / food supplements for standardization, responding to a global society

  Komatsu, K. (Principal Investigator), Toume, K. (Co-Investigator(Kenkyū-buntansha)) & ZHU, S. (Co-Investigator(Kenkyū-buntansha))

  Japan Society for the Promotion of Science

  2018/04/01 → 2021/03/31

  Project: Research Project

• Divergent Synthesis of Indole Alkaloids Using Regioselective Alkylations of Enaminones

  Nambu, H. (Principal Investigator)

  Japan Society for the Promotion of Science

  2018/04/01 → 2021/03/31

  Project: Research Project

• Transport mechanism of very long chain fatty acyl-CoA into peroxisomes mediated by peroxisomal ABC protein ABCD1

  Kawaguchi, K. (Principal Investigator)

  Japan Society for the Promotion of Science

  2018/04/01 → 2020/03/31

  Project: Research Project

• Development of therapeutic strategy for Alzheimer's disease via M2 microglia

  Kuboyama, T. (Principal Investigator) & Tohda, C. (Co-Investigator(Kenkyū-buntansha))

  Japan Society for the Promotion of Science

  2018/04/01 → 2021/03/31

  Project: Research Project

• Establishment of new identification method of the endoplasmic reticulum membrane scramblases based on the amino acid primary sequence

  Nakao, H. (PI)

  2017/08/25 → 2019/03/31

  Project: Research

• Elucidation of underlying mechanism of onset of stress vulnerability by environmental chemicals to explore biomakers

  Hirano, T. (Principal Investigator)

  Japan Society for the Promotion of Science

  2017/08/25 → 2019/03/31

  Project: Research Project

• Development of novel medical strategies in pre-disease by Kampo science and the mathematical science of complex systems

  Koizumi, K. (Principal Investigator) & Oku, M. (Co-Investigator(Kenkyū-buntansha))

  Japan Society for the Promotion of Science

  2017/07/18 → 2022/03/31

  Project: Research Project

• Genomic analysis of Shati/Nat8l to protect use methamphetamine

  Nitta, A. (PI)

  2017/06/30 → 2019/03/31

  Project: Research

  • Shati 100%
  • Nucleus Accumbens 65%
  • N-Acetyltransferase 56%
  • Knock-in Mouse Model 55%
  • Conditioned Place Preference 53%

• Development of novel multi-component synthesis of 1,4-dihydropyridines by auto-tandem catalysis

  Sugimoto, K. (PI)

  2017/04/01 → 2020/03/31

  Project: Research

• 生理活性植物メロテルペノイド生合成酵素の立体構造解明と機能的リデザイン

  Taura, F. (PI)

  2017/04/01 → 2019/03/31

  Project: Research

• 慢性期脊髄損傷の薬物治療；骨格筋萎縮と軸索断裂を改善する生薬医薬品の開発研究

  Tohda, C. (PI)

  2017/04/01 → 2022/03/31

  Project: Research

  • Alzheimer's Disease 100%
  • Alzheimer's Disease Model 71%
  • 5xFAD 67%
  • Axonal Growth 62%
  • Axonal Degeneration 55%

• Engineering of DABB-family enzymes to novel polyketide cyclase

  Morita, H. (CoI)

  2017/04/01 → 2020/03/31

  Project: Research

• Analyses of essential interactions of iminosugars with the Hex A active site and evaluation of their pharmacological chaperone effects for Tay-Sachs disease

  Kato, A. (PI)

  2017/04/01 → 2020/03/31

  Project: Research

• Physiological and pathophysiological properties of Parkinson's disease-related cation pump ATP13A2

  Fujii, T. (PI)

  2017/04/01 → 2020/03/31

  Project: Research

• Control of cell differentiation and proliferation by ultrasound: elucidation of the role of epigenome

  Tabuchi, Y. (PI) & Hasegawa, H. (CoI)

  2017/04/01 → 2020/03/31

  Project: Research

• Study of cationic drug efflux across the blood-retinal barrier

  Kubo, Y. (PI) & Akanuma, S.-I. (CoI)

  2017/04/01 → 2020/03/31

  Project: Research

• Regulation of mRNA metabolism by the transcription-coupled RNA methyltransferase PCIF1

  Hirose, Y. (PI)

  2017/04/01 → 2020/03/31

  Project: Research

• Comprehensive understanding of the phospholipid flip mechanism in the endoplasmic reticulum and establishment of the control technology of biomembrane dynamics

  Nakano, M. (PI) & Ikeda, K. (CoI)

  2017/04/01 → 2021/03/31

  Project: Research

• Development and biological application of thioamide-click type reactions

  Chiba, J. (PI)

  2017/04/01 → 2020/03/31

  Project: Research

  • Deoxyribonucleic Acid 100%
  • C-nucleosides 83%
  • C-Nucleoside 75%
  • Alkynyl 66%
  • Nucleobase 66%

• Effect of goreisan on rat mesenteric lymphtic vessels.

  Jo, M. (PI)

  2017/04/01 → 2020/03/31

  Project: Research

• 植物由来新規ポリケタイド閉環酵素の探索と物質生産

  Morita, H. (PI)

  2017/04/01 → 2019/03/31

  Project: Research

• カメルーン産薬用植物の抗菌活性成分に関する研究

  Awouafack, M. D. (PI) & Morita, H. (CoI)

  2016/11/07 → 2019/03/31

  Project: Research

• Establishment of highly effective therapy for food allergy by concomitant use of kakkonto with oral immunotherapy

  Yamamoto, T. (PI), Ito, Y. (CoI) & Nagata, Y. (CoI)

  2016/04/01 → 2019/03/31

  Project: Research

• Discovery of natural anticancer agents that inhibit cancer cells' tolerance to nutrition starvation and elucidation of their molecular mechanisms

  Awale, S. (PI)

  2016/04/01 → 2020/03/31

  Project: Research

• Functional interactions between inflammatory signal and growth singaling in the Warburg effect in cancer cells

  Sakurai, H. (PI)

  2016/04/01 → 2018/03/31

  Project: Research

• The foundation of developing drugs for retinal diseases by pharmaceutical drug-repositioning screening based on the distribution manner via the blood-retinal barrier

  Hosoya, K.-I. (PI), Akanuma, S.-I. (CoI), Matsuya, Y. (CoI), Abe, H. (CoI), Ando, T. (CoI) & Kubo, Y. (CoI)

  2016/04/01 → 2019/03/31

  Project: Research

• PKD2L1 cation channels regulate bitter taste reception

  Shimizu, T. (PI)

  2016/04/01 → 2019/03/31

  Project: Research

• Functional Analysis of transcription factor SOX10 in melanoma for norvel therapeutics

  Yokoyama, S. (PI)

  2016/04/01 → 2018/03/31

  Project: Research

• Adrenoleukodystrophy: effect of bone marrow transplantation in abcd1-deficient mouse

  Morita, M. (PI)

  2016/04/01 → 2019/03/31

  Project: Research

• the effects of CD206-positive macrophages on obesity-associated liver tumors

  Usui, I. (PI), Nakagawa, T. (CoPI) & Hayakawa, Y. (CoI)

  2016/04/01 → 2019/03/31

  Project: Research

• Noncanonical activation of receptor tyrosine kinases: next target mechanisms for cancer progression

  Sakurai, H. (PI), Ozawa, T. (CoI) & Kawasaki, Y. (CoI)

  2016/04/01 → 2019/03/31

  Project: Research

• Structural Study of basal transcription factor TFIIE

  Obita, T. (PI)

  2016/04/01 → 2019/03/31

  Project: Research

• Aggregation of amyloid-beta protein on size-controlled lipid nanoparticles

  Ikeda, K. (PI)

  2016/04/01 → 2018/03/31

  Project: Research

• Mode-of-action analysis of Kampo formulae and prediction of their new indications for a wide range of diseases

  Kadowaki, M. (PI), Shibahara, N. (CoI), Tohda, C. (CoI), Hayashi, S. (CoI), Yamanishi, Y. (CoI), Yamamoto, T. (CoI) & Umezaki, M. (CoI)

  2016/04/01 → 2019/03/31

  Project: Research

• Development of a TTR amyloidogenesis inhibitor based on the capture of transthyretin monomers

  Yokoyama, T. (PI)

  2016/04/01 → 2019/03/31

  Project: Research

• Application of chronotherapy to decrease the drug-induced peripheral neuropathy

  To, H. (PI)

  2016/04/01 → 2019/03/31

  Project: Research

• Molecular mechanisms of transport function at the BBB in epilepsy for normalizing cerebral PGE2 level

  Akanuma, S.-I. (PI), Hosoya, K.-I. (CoI), Kubo, Y. (CoI) & Tachikawa, M. (CoI)

  2016/04/01 → 2019/03/31

  Project: Research

• 高性能光ラベル法による脂質標的分子の同定および結合解析

  Tomohiro, T. (PI)

  2016/04/01 → 2018/03/31

  Project: Research

• Evaluation of Cx43 proteins for PGE2 release from retinal pigment epithelial cells for understanding the pathological role in age-related macular degeneration.

  Hosoya, K.-I. (PI), Kubo, Y. (CoI), Sakai, H. (CoI) & Tachikawa, M. (CoPI)

  2016/04/01 → 2018/03/31

  Project: Research

• Development of Novel Synthetic Methods of Fused-heterocyclic Systems by Domino-type Cycloaddition of o-Xylylene Intermediate

  Matsuya, Y. (PI), Kohyama, A. A. (CoPI) & Koresawa, E. (CoPI)

  2016/04/01 → 2018/03/31

  Project: Research

• Development of environmentally benign metal carbenoid reactions: For catalysts, asymmetric reactions, natural products synthesis

  Yakura, T. (PI)

  2016/04/01 → 2019/03/31

  Project: Research

• Role of CD206 Positive Macrophages in the Intestinal Homeostasis and Inflammatory Bowel Disease

  Hayashi, S. (PI)

  2015/04/01 → 2018/03/31

  Project: Research

• Analysis of multi-components of Wakan-yaku based on chemometric profiling

  Toume, K. (PI), Komatsu, K. (CoI) & Ohtsuki, T. (CoI)

  2015/04/01 → 2019/03/31

  Project: Research

• Comprehensive studies for the biotechnological production of daurichromenic acid, an anti-HIV natural product

  Taura, F. (PI), Akashi, T. (CoPI) & Morita, H. (CoPI)

  2015/04/01 → 2018/03/31

  Project: Research

• ゲルマニウム―アセチレンからなる拡張共役環状元素ブロック高分子の創出

  Tanimoto, H. (PI)

  2015/04/01 → 2017/03/31

  Project: Research