Faculty of Pharmaceutical Sciences

Projects

Projects per year 1996 2012 2013 2014 2015 2016 2018 2019 2020 2021 2022 2023 2024 2025 2029

• 80 Active
• 304 Finished

Projects per year

Search results

• Engineering of type III polyketide synthase by deletion and addition of residues

  Morita, H. (PI)

  2014/04/01 → 2016/03/31

  Project: Research

• Verification of relationships between dysfunction of the cell stress-protection system by exposures to multiple environmental chemicals and diseases

  Tabuchi, Y. (PI), Hoshi, N. (CoI) & Kondo, T. (CoI)

  2012/04/01 → 2016/03/31

  Project: Research

• 消化器癌に対する抗腫瘍和漢薬の確立および臨床応用に関する研究

  Tsukada, K. (PI), Ohnaga, T. (CoI), Morita, H. (CoI) & Nagata, T. (CoI)

  2015/04/01 → 2016/03/31

  Project: Research

• Structural basis of Archaeal ESCRT complex

  Obita, T. (PI)

  2014/04/01 → 2016/03/31

  Project: Research

• Development of therapeutics for diabetes with dysregulation of sleep/wake rhythm and depressive disorders by timed regulation of hypothalamic orexin system

  Sasaoka, T. (PI), Tsuneki, H. (CoI) & Wada, T. (CoI)

  2012/04/01 → 2016/03/31

  Project: Research

• エチニルピリジンオリゴマーが構築する超分子構造の観測と応用

  Ohishi, Y. (PI)

  2013/04/01 → 2016/03/31

  Project: Research

• ルイス塩基触媒と分子内ケイ素移動とを融合させた新規有機触媒反応システムの開発

  Matsuya, Y. (PI)

  2014/04/01 → 2016/03/31

  Project: Research

• Structure and molecular interactions in aggregation of amyloid beta protein

  Ikeda, K. (PI)

  2014/04/01 → 2016/03/31

  Project: Research

• Functional coupling between ion channels and scramblases in human TMEM16F-expressing cells

  Shimizu, T. (PI)

  2013/04/01 → 2016/03/31

  Project: Research

• Clarification of molecular and physiological properties of the acid-preventing barrier in gastric parietal cells

  Sakai, H. (PI), Sawaguchi, A. (CoI) & Ikari, A. (CoI)

  2013/04/01 → 2016/03/31

  Project: Research

• Neutron Diffraction Analysis of Human Farnesyl Pyrophosphate Synthase in Complex with Bisphosphonate

  Yokoyama, T. (PI)

  2013/04/01 → 2016/03/31

  Project: Research

• Design, Synthesis, and Structure-Activity Relationship Study of Novel Neuro-Protecting Drugs Based on Natural Product Hybridization

  Matsuya, Y. (PI), Sugimoto, K. (CoI) & Tohda, C. (CoI)

  2013/04/01 → 2016/03/31

  Project: Research

• Effect of obesity and diabetes on liver cancer and tumor-associated macrophage polarization

  Usui, I. (PI), Hayakawa, Y. (CoI) & Tsuneyama, K. (CoI)

  2013/04/01 → 2016/03/31

  Project: Research

• Evaluation of cationic drug transport system at the blood-retinal barrier to deliver the drugs to the retina

  Hosoya, K.-I. (PI), Akanuma, S.-I. (CoI), Kubo, Y. (CoI), Matsuya, Y. (CoI) & Takashima, T. (CoI)

  2013/04/01 → 2016/03/31

  Project: Research

• ABC protein subfamily D: Mechanisms about subcellular localization and substrate transport, and regulation of cell function

  今中常雄 (Principal Investigator) & Kawaguchi, K. (Co-Investigator(Kenkyū-buntansha))

  Japan Society for the Promotion of Science

  2014/04/01 → 2017/03/31

  Project: Research Project

• Explore molecular basis underlying formation of chemical diversity in genus Panax through RNA-Seq analysis of three Panax species with different chemical compositions

  Zhu, S. (Principal Investigator)

  Japan Society for the Promotion of Science

  2014/04/01 → 2017/03/31

  Project: Research Project

• Synthetic studies toward (+)-CJ-12,950 for the stereochemical elucidation and structure activity relationship studies

  Sugimoto, K. (PI)

  2014/04/01 → 2017/03/31

  Project: Research

• Role of pregnane X receptor in the preventive effect of Boiogito against experimentally induced cholestatic liver injury

  Watanabe, S. (PI)

  2014/04/01 → 2017/03/31

  Project: Research

• Control of cell differentiation by ultrasound through epigenetic mechanisms

  Tabuchi, Y. (PI)

  2014/04/01 → 2017/03/31

  Project: Research

• ゲルマニウム―アセチレンからなる拡張共役環状元素ブロック高分子の創出

  Tanimoto, H. (PI)

  2015/04/01 → 2017/03/31

  Project: Research

• Engineering of plant-specific polyketide scaffold synthetic enzymes to produce structural diversity of compounds

  Morita, H. (PI), Matsui, T. (CoI) & Kodama, T. (CoI)

  2014/04/01 → 2017/03/31

  Project: Research

• Design and synthesis of iminosugar-based pharmacological chaperone as a structure stabilizing agent for mutation enzyme

  Kato, A. (PI)

  2014/04/01 → 2017/03/31

  Project: Research

• ＦｔｓＺ阻害活性を基盤としたベトナム産植物中の抗生物質に関する研究

  Morita, H. (PI) & Nguyen, H. T. (CoI)

  2014/04/25 → 2017/03/31

  Project: Research

• Traditional medicine-based drug development-creation of new paradigm-

  Tohda, C. (PI), Kazuma, K. (CoI) & Konno, K. (CoI)

  2014/04/01 → 2017/03/31

  Project: Research

• Elucidation of the molecular components and regulatory mechanism of anion channels controlling the cell homeostasis and death

  Sakai, H. (PI) & Shimizu, T. (CoI)

  2015/04/01 → 2017/03/31

  Project: Research

• Elucidation of dynamic control of biomembrane functions by phospholipid transfer proteins

  Nakano, M. (PI) & Ikeda, K. (CoI)

  2014/04/01 → 2017/03/31

  Project: Research

• Study of cationic drug efflux across the blood-retinal barrier

  Kubo, Y. (PI), Akanuma, S.-I. (CoI), Hosoya, K.-I. (CoI) & Nishi, T. (CoI)

  2014/04/01 → 2017/03/31

  Project: Research

• A new mice model of bipolar disease for the drug developments

  Nitta, A. (PI), Muramatsu, S. I. (CoI), Uno, K. (CoI) & Miyamoto, Y. (CoI)

  2015/04/01 → 2017/03/31

  Project: Research

• Regulation of Arc gene transcription by SRF cofactors: mechanism and application for drug design in ASD

  Tabuchi, A. (PI), Mori, H. (CoI) & Fukuchi, M. (CoI)

  2014/04/01 → 2017/03/31

  Project: Research

• Development of novel anti-virus drugs by means of libraries of sialic acid derivatives possessing an anion at the 1-position

  Chiba, J. (PI), Hatanaka, Y. (CoI) & Tomohiro, T. (CoI)

  2013/04/01 → 2017/03/31

  Project: Research

• Impact of the cooperative effect of estrogen and orexin on abnormalities with emotion and metabolism in menopausal mice

  Sasaoka, T. (PI), Wada, T. (CoI) & Tsuneki, H. (CoI)

  2015/04/01 → 2017/03/31

  Project: Research

• Novel anti-cancer mechanism of the targeting of the association between receptor-type sodium pump and VSOR channels

  Fujii, T. (PI)

  2014/04/01 → 2017/03/31

  Project: Research

• Exploration of tumor-promoting inflammatory immune responses and its application for cancer treatment

  Hayakawa, Y. (PI)

  2014/04/01 → 2017/03/31

  Project: Research

• Synthetic studies on natural products containing highly substituted heterocyclic skeletons using ring-opening cyclization of spirocyclopropanes

  Nambu, H. (Principal Investigator)

  Japan Society for the Promotion of Science

  2015/04/01 → 2018/03/31

  Project: Research Project

• Role of CD206 Positive Macrophages in the Intestinal Homeostasis and Inflammatory Bowel Disease

  Hayashi, S. (PI)

  2015/04/01 → 2018/03/31

  Project: Research

• Comprehensive studies for the biotechnological production of daurichromenic acid, an anti-HIV natural product

  Taura, F. (PI), Akashi, T. (CoPI) & Morita, H. (CoPI)

  2015/04/01 → 2018/03/31

  Project: Research

• Strategy for designing selective rhamnosidase inhibitors: Synthesis and biological evaluation of L-DMDP cyclic isothioureas

  Adachi, I. (PI), Kato, A. (CoI) & Natori, Y. (CoI)

  2015/04/01 → 2018/03/31

  Project: Research

• Study on medicinal plants in Asia for sustainable use of traditional medicines

  Komatsu, K. (PI), Toume, K. (CoI), Tohda, C. (CoI), Andoh, T. (CoI), Cai, S. Q. (CoI), He, Y. M. (CoI), Javzan, B. (CoI) & Myint, Y. Y. (CoI)

  2015/04/01 → 2018/03/31

  Project: Research

• Synthetic study of highly strained anti-cancer natural products by way of umpolung strategy using reactive chemical species

  Tanimoto, H. (PI)

  2015/04/01 → 2018/03/31

  Project: Research

• Investigation of pathogenic mechanisms and Kampo medicine-based preventive and therapeutic strategy for ADHD using an epigenetic animal model.

  Matsumoto, K. (PI), Awale, S. (CoI), 藤原, 博典 (CoI) & Hori, E. (CoI)

  2015/04/01 → 2018/03/31

  Project: Research

• Functional interactions between inflammatory signal and growth singaling in the Warburg effect in cancer cells

  Sakurai, H. (PI)

  2016/04/01 → 2018/03/31

  Project: Research

• Research on diarrhea-improving effect of Goreisan via the expression of aquaporins in intestine

  Shibahara, N. (PI), Kimura, M. (CoI), Wu, Y. (CoI) & Qiqige, S. (CoI)

  2015/04/01 → 2018/03/31

  Project: Research

• Elucidation of the molecular mechanism producing diterpenes with various tetracyclic skeletons in plant cells

  Yamamura, Y. (PI) & Lee, J. (CoI)

  2015/04/01 → 2018/03/31

  Project: Research

• Functional Analysis of transcription factor SOX10 in melanoma for norvel therapeutics

  Yokoyama, S. (PI)

  2016/04/01 → 2018/03/31

  Project: Research

• Protective effects of Shati/Nat8l on the dysfunction induced by addictive drugs

  Nitta, A. (PI), Muramatsu, S. I. (CoI) & Uno, K. (CoI)

  2015/04/01 → 2018/03/31

  Project: Research

• Regulation of inflammatory cytokine signaling by TRAF5

  So, T. (PI)

  2015/04/01 → 2018/03/31

  Project: Research

• Development of therapeutic strategy against obesity-associated chronic inflammations based on the mechanism involved in sex-specific difference of Treg localization in adipose tissue.

  Wada, T. (PI), Sasaoka, T. (CoI), Saito, S. (CoI), Sasahara, M. (CoI), Sameshima, A. (CoI), Ishikawa, A. (CoI), Ito, T. (CoI), Ikurumi, M. (CoI) & Tanaka, T. (CoI)

  2015/04/01 → 2018/03/31

  Project: Research

• Aggregation of amyloid-beta protein on size-controlled lipid nanoparticles

  Ikeda, K. (PI)

  2016/04/01 → 2018/03/31

  Project: Research

• Mechanisms of the pharmacokinetic variability and optimization of drug therapy in children with congenital heart disease

  Taguchi, M. (PI), Ichida, F. (CoI) & Hirono, K. (CoI)

  2015/04/01 → 2018/03/31

  Project: Research

• Functional and structural analyses of organic cation transporter in the intestine.

  Hashimoto, Y. (PI)

  2015/04/01 → 2018/03/31

  Project: Research