Research output per year
Research output per year
Research output
- 1 - 50 out of 123 results
Search results
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2025
Nicotinamide riboside and nicotinamide mononucleotide facilitate NAD+ synthesis via enterohepatic circulation
Yaku, K., Palikhe, S., Iqbal, T., Hayat, F., Watanabe, Y., Fujisaka, S., Izumi, H., Yoshida, T., Karim, M., Uchida, H., Nawaz, A., Tobe, K., Mori, H., Migaud, M. E. & Nakagawa, T., 2025/03/21, In: Science Advances. 11, 12, eadr1538.Research output: Contribution to journal › Article › peer-review
Open Access -
Role of transforming growth factor-β1 in regulating adipocyte progenitors
Phuong, N. Q., Bilal, M., Nawaz, A., Anh, L. D., Memoona, Aslam, M. R., Khalid, S., Kado, T., Watanabe, Y., Nishimura, A., Igarashi, Y., Okabe, K., Hirabayashi, K., Yamamoto, S., Nakagawa, T., Mori, H., Usui, I., Fujisaka, S., Hayashi, R. & Tobe, K., 2025/12, In: Scientific Reports. 15, 1, 941.Research output: Contribution to journal › Article › peer-review
Open Access -
2024
Association between serum interleukin-17 levels and ectopic bone formation in OPLL patients with DISH
He, Z., Canh Tung, N. T., Yahara, Y., Makino, H., Yasuda, T., Seki, S., Suzuki, K., Futakawa, H., Kamei, K. & Kawaguchi, Y., 2024/08/01, In: Rheumatology (United Kingdom). 63, 8, p. 2268-2277 10 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Chronic Endurance Exercise Impairs Niacin Nutritional Status in Mice
Mizutani, A., Nishikawa, T., Fujigaki, H., Yamamoto, Y., Saito, K., Hatayama, S. & Fukuwatari, T., 2024, In: Journal of Nutritional Science and Vitaminology. 70, 3, p. 185-192 8 p.Research output: Contribution to journal › Article › peer-review
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Chronic Ethanol Intake Impairs Niacin Nutritional Status in Mice
Mizutani, A., Goto, C., Fujigaki, H., Yamamoto, Y., Saito, K., Hatayama, S. & Fukuwatari, T., 2024, In: Journal of Nutritional Science and Vitaminology. 70, 1, p. 1-8 8 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Identification of herbal drug extracts that promote growth of Akkermansia muciniphila in high-fat diet fed mice
Fujisaka, S., Watanabe, Y., Toume, K., Morinaga, Y., Nawaz, A., Kado, T., Nishimura, A., Bilal, M., Aslam, M. R., Igarashi, Y., Nakagawa, Y. & Tobe, K., 2024/07, In: Diabetology International. 15, 3, p. 495-506 12 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Impact of the SIK3 pathway inhibition on osteoclast differentiation via oxidative phosphorylation
Kamei, K., Yahara, Y., Kim, J.-D., Tsuji, M., Iwasaki, M., Takemori, H., Seki, S., Makino, H., Futakawa, H., Hirokawa, T., Tung, N. T. C., Nakagawa, T. & Kawaguchi, Y., 2024/07/20, In: Journal of Bone and Mineral Research. 39, 9, p. 1340 1355 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Mitochondrial Redox Status Regulates Glycogen Metabolism via Glycogen Phosphorylase Activity
Sakamoto, I., Shibuya, S., Nojiri, H., Takeno, K., Nishimune, H., Yaku, K., Nakagawa, T., Ishijima, M. & Shimizu, T., 2024/11, In: Antioxidants. 13, 11, 1421.Research output: Contribution to journal › Article › peer-review
Open Access -
2023
Adipocyte NMNAT1 expression is essential for nuclear NAD+ biosynthesis but dispensable for regulating thermogenesis and whole-body energy metabolism
Yamaguchi, S., Kojima, D., Iqbal, T., Kosugi, S., Franczyk, M. P., Qi, N., Sasaki, Y., Yaku, K., Kaneko, K., Kinouchi, K., Itoh, H., Hayashi, K., Nakagawa, T. & Yoshino, J., 2023/09/24, In: Biochemical and Biophysical Research Communications. 674, p. 162-169 8 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Asymmetric Load Transmission Induces Facet Joint Subchondral Sclerosis and Hypertrophy in Patients with Idiopathic Adolescent Scoliosis: Evaluation Using Finite Element Model and Surgical Specimen
Yahara, Y., Seki, S., Makino, H., Futakawa, H., Kamei, K. & Kawaguchi, Y., 2023/12, In: JBMR Plus. 7, 12, e10812.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Blood levels of nicotinic acid negatively correlate with hearing ability in healthy older men
Nakagawa-Nagahama, Y., Igarashi, M., Miura, M., Kashiwabara, K., Yaku, K., Fukamizu, Y., Sato, T., Sakurai, T., Nakagawa, T., Kadowaki, T. & Yamauchi, T., 2023/02/15, In: BMC Geriatrics. 23, 1, 97.Research output: Contribution to journal › Article › peer-review
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Blood levels of nicotinic acid negatively correlate with hearing ability in healthy older men
Nakagawa-Nagahama, Y., Igarashi, M., Miura, M., Kashiwabara, K., Yaku, K., Fukamizu, Y., Sato, T., Sakurai, T., Nakagawa, T., Kadowaki, T. & Yamauchi, T., 2023/12, In: BMC Geriatrics. 23, 1, 97.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Deletion of Nmnat1 in Skeletal Muscle Leads to the Reduction of NAD Levels but Has No Impact on Skeletal Muscle Morphology and Fiber Types
Karim, M., Iqbal, T., Nawaz, A., Yaku, K. & Nakagawa, T., 2023, In: Journal of Nutritional Science and Vitaminology. 69, 3, p. 184-189 6 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Determining Bone-forming Ability and Frequency of Skeletal Stem Cells by Kidney Capsule Transplantation and Limiting Dilution Assay.
Uchida, H., Maruyama, T. & Hsu, W., 2023/03/20, In: Bio-protocol. 13, 6Research output: Contribution to journal › Article
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Establishment of Model Mice to Evaluate Low Niacin Nutritional Status
Mizutani, A., Sato, M., Fujigaki, H., Yamamoto, Y., Saito, K., Hatayama, S. & Fukuwatari, T., 2023, In: Journal of Nutritional Science and Vitaminology. 69, 5, p. 305-313 9 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Isoxanthohumol improves obesity and glucose metabolism via inhibiting intestinal lipid absorption with a bloom of Akkermansia muciniphila in mice
Watanabe, Y., Fujisaka, S., Morinaga, Y., Watanabe, S., Nawaz, A., Hatta, H., Kado, T., Nishimura, A., Bilal, M., Aslam, M. R., Honda, K., Nakagawa, Y., Softic, S., Hirabayashi, K., Nakagawa, T., Nagai, Y. & Tobe, K., 2023/11, In: Molecular Metabolism. 77, 101797.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
Niacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma
Nomura, M., Ohuchi, M., Sakamoto, Y., Kudo, K., Yaku, K., Soga, T., Sugiura, Y., Morita, M., Hayashi, K., Miyahara, S., Sato, T., Yamashita, Y., Ito, S., Kikuchi, N., Sato, I., Saito, R., Yaegashi, N., Fukuhara, T., Yamada, H. & Shima, H. & 9 others, , 2023/12, In: Nature Communications. 14, 1, 8095.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Progressive paravertebral ligament ossification and pseudoarthrosis in the thoracic spine due to loss of function of the PHEX gene in a patient with X-linked hypophosphatemic rickets
Yahara, Y., Niimi, H., Sugie, N., Seki, S., Ueshima, R., Makino, H., Kamei, K., Kitajima, I. & Kawaguchi, Y., 2023/01, In: Journal of Orthopaedic Science. 28, 1, p. 295-298 4 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Regional contributions of D-serine to Alzheimer’s disease pathology in male AppNL–G–F/NL–G–F mice
Ni, X., Inoue, R., Wu, Y., Yoshida, T., Yaku, K., Nakagawa, T., Saito, T., Saido, T. C., Takao, K. & Mori, H., 2023, In: Frontiers in Aging Neuroscience. 15, 1211067.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Rod Rotation with Outrigger Is Substantial for Correcting Apical Hypokyphosis in Patients with Adolescent Idiopathic Scoliosis: Novel Outrigger Device for Concave Rod Rotation
Seki, S., Makino, H., Yahara, Y., Kamei, K., Futakawa, H., Yasuda, T., Suzuki, K., Nakano, M. & Kawaguchi, Y., 2023/11, In: Journal of Clinical Medicine. 12, 21, 6780.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Sacroiliac Joint Variation in Patients With Ossification of the Posterior Longitudinal Ligament
Tung, N. T. C., Yahara, Y., Yasuda, T., Seki, S., Suzuki, K., Watanabe, K., Makino, H., Kamei, K. & Kawaguchi, Y., 2023/07, In: Global Spine Journal. 13, 6, p. 1474-1480 7 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
2022
Accuracy of pedicle screw placement using patient-specific template guide system
Fujita, R., Oda, I., Takeuchi, H., Oshima, S., Fujiya, M., Yahara, Y. & Kawaguchi, Y., 2022/03, In: Journal of Orthopaedic Science. 27, 2, p. 348-354 7 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
A deep convolutional neural network to predict the curve progression of adolescent idiopathic scoliosis: a pilot study
Yahara, Y., Tamura, M., Seki, S., Kondo, Y., Makino, H., Watanabe, K., Kamei, K., Futakawa, H. & Kawaguchi, Y., 2022/12, In: BMC Musculoskeletal Disorders. 23, 1, 610.Research output: Contribution to journal › Article › peer-review
Open Access24 Scopus citations -
Association of Ligamentum Flavum Hypertrophy with Adolescent Idiopathic Scoliosis Progression—Comparative Microarray Gene Expression Analysis
Seki, S., Iwasaki, M., Makino, H., Yahara, Y., Kondo, M., Kamei, K., Futakawa, H., Nogami, M., Watanabe, K., Tran Canh Tung, N., Hirokawa, T., Tsuji, M. & Kawaguchi, Y., 2022/05/01, In: International Journal of Molecular Sciences. 23, 9, 5038.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Chronic nicotinamide mononucleotide supplementation elevates blood nicotinamide adenine dinucleotide levels and alters muscle function in healthy older men
Igarashi, M., Nakagawa-nagahama, Y., Miura, M., Kashiwabara, K., Yaku, K., Sawada, M., Sekine, R., Fukamizu, Y., Sato, T., Sakurai, T., Sato, J., Ino, K., Kubota, N., Nakagawa, T., Kadowaki, T. & Yamauchi, T., 2022/05/01, In: npj Aging. 8, 1Research output: Contribution to journal › Article › peer-review
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Depletion of CD206+ M2-like macrophages induces fibro-adipogenic progenitors activation and muscle regeneration
Nawaz, A., Bilal, M., Fujisaka, S., Kado, T., Aslam, M. R., Ahmed, S., Okabe, K., Igarashi, Y., Watanabe, Y., Kuwano, T., Tsuneyama, K., Nishimura, A., Nishida, Y., Yamamoto, S., Sasahara, M., Imura, J., Mori, H., Matzuk, M. M., Kudo, F. & Manabe, I. & 4 others, , 2022/12, In: Nature Communications. 13, 1, 7058.Research output: Contribution to journal › Article › peer-review
Open Access41 Scopus citations -
Direct Reprogramming and Induction of Human Dermal Fibroblasts to Differentiate into iPS-Derived Nucleus Pulposus-like Cells in 3D Culture
Seki, S., Iwasaki, M., Makino, H., Yahara, Y., Miyazaki, Y., Kamei, K., Futakawa, H., Nogami, M., Tung, N. T. C., Hirokawa, T., Tsuji, M. & Kawaguchi, Y., 2022/04/01, In: International Journal of Molecular Sciences. 23, 7, 4059.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Efficacy of surgeon-directed postoperative local injection with an analgesic mixture in posterior fusion surgery for adolescent idiopathic scoliosis
Makino, H., Seki, S., Kamei, K., Yahara, Y. & Kawaguchi, Y., 2022/12, In: BMC Musculoskeletal Disorders. 23, 1, 208.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Encapsulation of Primary Salivary Gland Acinar Cell Clusters and Intercalated Ducts (AIDUCs) within Matrix Metalloproteinase (MMP)-Degradable Hydrogels to Maintain Tissue Structure and Function
Song, Y., Sharipol, A., Uchida, H., Ingalls, M. H., Piraino, L., Mereness, J. A., Moyston, T., DeLouise, L. A., Ovitt, C. E. & Benoit, D. S. W., 2022/04/06, In: Advanced Healthcare Materials. 11, 7, 2101948.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Food odor perception promotes systemic lipid utilization
Tsuneki, H., Sugiyama, M., Ito, T., Sato, K., Matsuda, H., Onishi, K., Yubune, K., Matsuoka, Y., Nagai, S., Yamagishi, T., Maeda, T., Honda, K., Okekawa, A., Watanabe, S., Yaku, K., Okuzaki, D., Otsubo, R., Nomoto, M., Inokuchi, K. & Nakagawa, T. & 3 others, , 2022/11, In: Nature Metabolism. 4, 11, p. 1514-1531Research output: Contribution to journal › Article › peer-review
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Food odor perception promotes systemic lipid utilization
Tsuneki, H., Sugiyama, M., Ito, T., Sato, K., Matsuda, H., Onishi, K., Yubune, K., Matsuoka, Y., Nagai, S., Yamagishi, T., Maeda, T., Honda, K., Okekawa, A., Watanabe, S., Yaku, K., Okuzaki, D., Otsubo, R., Nomoto, M., Inokuchi, K. & Nakagawa, T. & 3 others, , 2022/11, In: Nature Metabolism. 4, 11, p. 1514-1531 18 p.Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
Loss of hepatic Nmnat1 has no impact on diet-induced fatty liver disease
Iqbal, T., Nawaz, A., Karim, M., Yaku, K., Hikosaka, K., Matsumoto, M. & Nakagawa, T., 2022/12/25, In: Biochemical and Biophysical Research Communications. 636, p. 89-95 7 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Morphological characteristics of DISH in patients with OPLL and its association with high-sensitivity CRP: Inflammatory DISH
Nguyen, T. C. T., Yahara, Y., Yasuda, T., Seki, S., Suzuki, K., Watanabe, K., Makino, H., Kamei, K., Mori, K. & Kawaguchi, Y., 2022/10/01, In: Rheumatology (United Kingdom). 61, 10, p. 3981-3988 8 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Nmnat3 deficiency in hemolytic anemia exacerbates malaria infection
Mahmood, A., Yaku, K., Hikosaka, K., Gulshan, M., Inoue, S. I., Kobayashi, F. & Nakagawa, T., 2022/12/31, In: Biochemical and Biophysical Research Communications. 637, p. 58-65 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Oral Administration of Nicotinamide Mononucleotide Is Safe and Efficiently Increases Blood Nicotinamide Adenine Dinucleotide Levels in Healthy Subjects
Okabe, K., Yaku, K., Uchida, Y., Fukamizu, Y., Sato, T., Sakurai, T., Tobe, K. & Nakagawa, T., 2022/04/11, In: Frontiers in Nutrition. 9Research output: Contribution to journal › Article › peer-review
62 Scopus citations -
Serum Periostin Level Reflects Progression of Ossification of the Posterior Longitudinal Ligament
Kawaguchi, Y., Kitajima, I., Yasuda, T., Seki, S., Suzuki, K., Makino, H., Ujihara, Y., Ueno, T., Canh Tung, N. T. & Yahara, Y., 2022/02/04, In: JBJS Open Access. 7, 1, e21.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Short-term and bystander effects of radiation on murine submandibular glands
Uchida, H., Ingalls, M. H., Maruyama, E. O., Johnston, C. J., Hernady, E., Faustoferri, R. C. & Ovitt, C. E., 2022/11, In: DMM Disease Models and Mechanisms. 15, 11Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
2021
Anti-cancer potential of natural products containing (6H-dibenzo[b,d]pyran-6-one) framework using docking tools
Jeelani, I., Abe, H., Nawaz, A., Bhosale, M., Ahmad, S., Jamadar, A., Ahmed, K., Qadir, T., Amin, A., Sharma, P. K. & Abidi, S., 2021/09, In: Pakistan Journal of Pharmaceutical Sciences. 34, 5, p. 1995-2002 8 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Astaxanthin, a marine carotenoid, maintains the tolerance and integrity of adipose tissue and contributes to its healthy functions
Nawaz, A., Nishida, Y., Takikawa, A., Fujisaka, S., Kado, T., Aminuddin, A., Bilal, M., Jeelani, I., Aslam, M. R., Nishimura, A., Kuwano, T., Watanabe, Y., Igarashi, Y., Okabe, K., Ahmed, S., Manzoor, A., Usui, I., Yagi, K., Nakagawa, T. & Tobe, K., 2021/12, In: Nutrients. 13, 12, 4374.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
BST1 regulates nicotinamide riboside metabolism via its glycohydrolase and base-exchange activities
Yaku, K., Palikhe, S., Izumi, H., Yoshida, T., Hikosaka, K., Hayat, F., Karim, M., Iqbal, T., Nitta, Y., Sato, A., Migaud, M. E., Ishihara, K., Mori, H. & Nakagawa, T., 2021/12, In: Nature Communications. 12, 1, 6767.Research output: Contribution to journal › Article › peer-review
Open Access56 Scopus citations -
CD206+ macrophage is an accelerator of endometriotic-like lesion via promoting angiogenesis in the endometriosis mouse model
Ono, Y., Yoshino, O., Hiraoka, T., Sato, E., Furue, A., Nawaz, A., Hatta, H., Fukushi, Y., Wada, S., Tobe, K., Hirota, Y., Osuga, Y., Unno, N. & Saito, S., 2021/12, In: Scientific Reports. 11, 1, 853.Research output: Contribution to journal › Article › peer-review
Open Access33 Scopus citations -
Development of a functional salivary gland tissue chip with potential for high-content drug screening
Song, Y., Uchida, H., Sharipol, A., Piraino, L., Mereness, J. A., Ingalls, M. H., Rebhahn, J., Newlands, S. D., DeLouise, L. A., Ovitt, C. E. & Benoit, D. S. W., 2021/12, In: Communications Biology. 4, 1, 361.Research output: Contribution to journal › Article › peer-review
Open Access35 Scopus citations -
Fate of adipocyte progenitors during adipogenesis in mice fed a high-fat diet
Bilal, M., Nawaz, A., Kado, T., Aslam, M. R., Igarashi, Y., Nishimura, A., Watanabe, Y., Kuwano, T., Liu, J., Miwa, H., Era, T., Ikuta, K., Imura, J., Yagi, K., Nakagawa, T., Fujisaka, S. & Tobe, K., 2021/12, In: Molecular Metabolism. 54, 101328.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
Generation and characterization of a Meflin- CreERT2transgenic line for lineage tracing in white adipose tissue
Kuwano, T., Izumi, H., Aslam, M. R., Igarashi, Y., Bilal, M., Nishimura, A., Watanabe, Y., Nawaz, A., Kado, T., Ikuta, K., Yamamoto, S., Sasahara, M., Fujisaka, S., Yagi, K., Mori, H. & Tobe, K., 2021/03, In: PLoS ONE. 16, 3 March, e0248267.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Orotic acid protects pancreatic β cell by p53 inactivation in diabetic mouse model
Fushimura, Y., Hoshino, A., Furukawa, S., Nakagawa, T., Hino, T., Taminishi, S., Minami, Y., Urata, R., Iwai-kanai, E. & Matoba, S., 2021/12/01, In: Biochemical and Biophysical Research Communications. 585, p. 191-195Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Simultaneous measurement of amino acid enantiomers in aged mouse brain samples by lc/ms/ms combined with derivatization using nα-(5-fluoro-2,4-dinitrophenyl)-l-leucinamide (l-fdla)
Yamamoto, T., Yaku, K. & Nakagawa, T., 2021/01, In: Metabolites. 11, 1, p. 1-13 13 p., 57.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Tumor-propagating side population cells are a dynamic subpopulation in undifferentiated pleomorphic sarcoma
Tang, Y. J., Puviindran, V., Xiang, Y., Yahara, Y., Zhang, H., Nadesan, P., Diao, Y., Kirsch, D. G. & Alman, B. A., 2021/11/22, In: JCI Insight. 6, 22, e148768.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
2020
Astaxanthin stimulates mitochondrial biogenesis in insulin resistant muscle via activation of AMPK pathway
Nishida, Y., Nawaz, A., Kado, T., Takikawa, A., Igarashi, Y., Onogi, Y., Wada, T., Sasaoka, T., Yamamoto, S., Sasahara, M., Imura, J., Tokuyama, K., Usui, I., Nakagawa, T., Fujisaka, S., Kunimasa, Y. & Tobe, K., 2020/02/01, In: Journal of Cachexia, Sarcopenia and Muscle. 11, 1, p. 241-258 18 p.Research output: Contribution to journal › Article › peer-review
Open Access126 Scopus citations -
Bofutsushosan improves gut barrier function with a bloom of Akkermansia muciniphila and improves glucose metabolism in mice with diet-induced obesity
Fujisaka, S., Usui, I., Nawaz, A., Igarashi, Y., Okabe, K., Furusawa, Y., Watanabe, S., Yamamoto, S., Sasahara, M., Watanabe, Y., Nagai, Y., Yagi, K., Nakagawa, T. & Tobe, K., 2020/12/01, In: Scientific Reports. 10, 1, 5544.Research output: Contribution to journal › Article › peer-review
Open Access66 Scopus citations -
CD206+ M2-Like Macrophages Are Essential for Successful Implantation
Ono, Y., Yoshino, O., Hiraoka, T., Sato, E., Fukui, Y., Ushijima, A., Nawaz, A., Hirota, Y., Wada, S., Tobe, K., Nakashima, A., Osuga, Y. & Saito, S., 2020/10/23, In: Frontiers in Immunology. 11, 557184.Research output: Contribution to journal › Article › peer-review
Open Access50 Scopus citations