Faculty of Pharmaceutical Sciences

Projects

Projects per year 1996 2012 2013 2014 2015 2016 2018 2019 2020 2021 2022 2023 2024 2025 2029

• 80 Active
• 304 Finished

Projects per year

Search results

• Finished

  Collection of new natural sources and analysis of their chemical constituents and construction of genetic resource bank

  Morita, H. (PI), 伊藤卓也. (CoI) & Wong, C. P. (CoI)

  2015/04/01 → 2019/03/31

  Project: Research

• Strategy for designing selective rhamnosidase inhibitors: Synthesis and biological evaluation of L-DMDP cyclic isothioureas

  Adachi, I. (PI), Kato, A. (CoI) & Natori, Y. (CoI)

  2015/04/01 → 2018/03/31

  Project: Research

• Study on medicinal plants in Asia for sustainable use of traditional medicines

  Komatsu, K. (PI), Toume, K. (CoI), Tohda, C. (CoI), Andoh, T. (CoI), Cai, S. Q. (CoI), He, Y. M. (CoI), Javzan, B. (CoI) & Myint, Y. Y. (CoI)

  2015/04/01 → 2018/03/31

  Project: Research

• 消化器癌に対する抗腫瘍和漢薬の確立および臨床応用に関する研究

  Tsukada, K. (PI), Ohnaga, T. (CoI), Morita, H. (CoI) & Nagata, T. (CoI)

  2015/04/01 → 2016/03/31

  Project: Research

• Synthetic study of highly strained anti-cancer natural products by way of umpolung strategy using reactive chemical species

  Tanimoto, H. (PI)

  2015/04/01 → 2018/03/31

  Project: Research

• Investigation of pathogenic mechanisms and Kampo medicine-based preventive and therapeutic strategy for ADHD using an epigenetic animal model.

  Matsumoto, K. (PI), Awale, S. (CoI), 藤原, 博典 (CoI) & Hori, E. (CoI)

  2015/04/01 → 2018/03/31

  Project: Research

• Research on diarrhea-improving effect of Goreisan via the expression of aquaporins in intestine

  Shibahara, N. (PI), Kimura, M. (CoI), Wu, Y. (CoI) & Qiqige, S. (CoI)

  2015/04/01 → 2018/03/31

  Project: Research

• Elucidation of the molecular mechanism producing diterpenes with various tetracyclic skeletons in plant cells

  Yamamura, Y. (PI) & Lee, J. (CoI)

  2015/04/01 → 2018/03/31

  Project: Research

• Elucidation of the molecular components and regulatory mechanism of anion channels controlling the cell homeostasis and death

  Sakai, H. (PI) & Shimizu, T. (CoI)

  2015/04/01 → 2017/03/31

  Project: Research

• Elucidation of mechanism of itch transmission to spinal cord using in vivo patch clamp and three-dimensional electron microscope.

  Uta, D. (PI), Sakamoto, H. (CoI) & Kiguchi, N. (CoI)

  2015/04/01 → 2019/03/31

  Project: Research

• Protective effects of Shati/Nat8l on the dysfunction induced by addictive drugs

  Nitta, A. (PI), Muramatsu, S. I. (CoI) & Uno, K. (CoI)

  2015/04/01 → 2018/03/31

  Project: Research

• Regulation of inflammatory cytokine signaling by TRAF5

  So, T. (PI)

  2015/04/01 → 2018/03/31

  Project: Research

• Development of therapeutic strategy against obesity-associated chronic inflammations based on the mechanism involved in sex-specific difference of Treg localization in adipose tissue.

  Wada, T. (PI), Sasaoka, T. (CoI), Saito, S. (CoI), Sasahara, M. (CoI), Sameshima, A. (CoI), Ishikawa, A. (CoI), Ito, T. (CoI), Ikurumi, M. (CoI) & Tanaka, T. (CoI)

  2015/04/01 → 2018/03/31

  Project: Research

• Mechanisms of the pharmacokinetic variability and optimization of drug therapy in children with congenital heart disease

  Taguchi, M. (PI), Ichida, F. (CoI) & Hirono, K. (CoI)

  2015/04/01 → 2018/03/31

  Project: Research

• Functional and structural analyses of organic cation transporter in the intestine.

  Hashimoto, Y. (PI)

  2015/04/01 → 2018/03/31

  Project: Research

• A new mice model of bipolar disease for the drug developments

  Nitta, A. (PI), Muramatsu, S. I. (CoI), Uno, K. (CoI) & Miyamoto, Y. (CoI)

  2015/04/01 → 2017/03/31

  Project: Research

• Elucidation of the splicing regulatory function of an intrinsically disordered protein PQBP1

  Mizuguchi, M. (PI) & Obita, T. (CoI)

  2015/04/01 → 2018/03/31

  Project: Research

• Studies on novel insulin-sensitizing agent based on SHIP2 inhibitors

  Toyooka, N. (PI), Sasaoka, T. (CoI), Wada, T. (CoI) & Goda, H. H. (CoI)

  2015/04/01 → 2018/03/31

  Project: Research

• Radiosensitization based on intracellular redox control in cancer stem cells

  Kondo, T. (PI), Tabuchi, Y. (CoI), Matsuya, Y. (CoI), Ogawa, R. (PI) & Cho, K. (CoI)

  2015/04/01 → 2018/03/31

  Project: Research

• Impact of the cooperative effect of estrogen and orexin on abnormalities with emotion and metabolism in menopausal mice

  Sasaoka, T. (PI), Wada, T. (CoI) & Tsuneki, H. (CoI)

  2015/04/01 → 2017/03/31

  Project: Research

• Determining factors for giving structural diversity and analysis of temporospatial dynamics of onjisaponins

  Lee, J. (PI), Yamamura, Y. (CoI), Yamagaki, T. (CoI), Tatsuo, Y. (CoI), Takao, Y. (CoI) & Murakami, Y. (CoI)

  2015/04/01 → 2018/03/31

  Project: Research

• Transcriptional regulatory mechanism of the RNA polymerase II initiation complex by the chromatin remodeling complex

  Tanaka, A. (PI)

  2015/04/01 → 2018/03/31

  Project: Research

• Significance of homeodynamic regulation by hypothalamic orexin in preventing obesity and type 2 diabetes

  Tsuneki, H. (PI) & Sasaoka, T. (CoI)

  2015/04/01 → 2018/03/31

  Project: Research

• Identification of Scientific evidence for Traditional Kampo theory by gene expression analysis

  Saiki, I. (PI) & Yokoyama, S. (CoI)

  2015/04/01 → 2018/03/31

  Project: Research

• Structural analysis of membrane protein based on multi-labeled sites

  Tomohiro, T. (PI), Chiba, J. (CoI), Shimizu, T. (CoI) & Matsunaga, S. (CoI)

  2015/04/01 → 2018/03/31

  Project: Research

• Synthetic studies on natural products containing highly substituted heterocyclic skeletons using ring-opening cyclization of spirocyclopropanes

  Nambu, H. (Principal Investigator)

  Japan Society for the Promotion of Science

  2015/04/01 → 2018/03/31

  Project: Research Project

• ＦｔｓＺ阻害活性を基盤としたベトナム産植物中の抗生物質に関する研究

  Morita, H. (PI) & Nguyen, H. T. (CoI)

  2014/04/25 → 2017/03/31

  Project: Research

• がん悪性化に関わる炎症を制御する生理活性物質の探索

  Banbury, L. L. (PI) & Hayakawa, Y. (CoI)

  2014/04/25 → 2015/03/31

  Project: Research

• Synthetic studies toward (+)-CJ-12,950 for the stereochemical elucidation and structure activity relationship studies

  Sugimoto, K. (PI)

  2014/04/01 → 2017/03/31

  Project: Research

• Role of pregnane X receptor in the preventive effect of Boiogito against experimentally induced cholestatic liver injury

  Watanabe, S. (PI)

  2014/04/01 → 2017/03/31

  Project: Research

• Control of cell differentiation by ultrasound through epigenetic mechanisms

  Tabuchi, Y. (PI)

  2014/04/01 → 2017/03/31

  Project: Research

• Engineering of plant-specific polyketide scaffold synthetic enzymes to produce structural diversity of compounds

  Morita, H. (PI), Matsui, T. (CoI) & Kodama, T. (CoI)

  2014/04/01 → 2017/03/31

  Project: Research

• Engineering of type III polyketide synthase by deletion and addition of residues

  Morita, H. (PI)

  2014/04/01 → 2016/03/31

  Project: Research

• Design and synthesis of iminosugar-based pharmacological chaperone as a structure stabilizing agent for mutation enzyme

  Kato, A. (PI)

  2014/04/01 → 2017/03/31

  Project: Research

• Traditional medicine-based drug development-creation of new paradigm-

  Tohda, C. (PI), Kazuma, K. (CoI) & Konno, K. (CoI)

  2014/04/01 → 2017/03/31

  Project: Research

• Elucidation of dynamic control of biomembrane functions by phospholipid transfer proteins

  Nakano, M. (PI) & Ikeda, K. (CoI)

  2014/04/01 → 2017/03/31

  Project: Research

• Structural basis of Archaeal ESCRT complex

  Obita, T. (PI)

  2014/04/01 → 2016/03/31

  Project: Research

• Study of cationic drug efflux across the blood-retinal barrier

  Kubo, Y. (PI), Akanuma, S.-I. (CoI), Hosoya, K.-I. (CoI) & Nishi, T. (CoI)

  2014/04/01 → 2017/03/31

  Project: Research

• ルイス塩基触媒と分子内ケイ素移動とを融合させた新規有機触媒反応システムの開発

  Matsuya, Y. (PI)

  2014/04/01 → 2016/03/31

  Project: Research

• Structure and molecular interactions in aggregation of amyloid beta protein

  Ikeda, K. (PI)

  2014/04/01 → 2016/03/31

  Project: Research

• Regulation of Arc gene transcription by SRF cofactors: mechanism and application for drug design in ASD

  Tabuchi, A. (PI), Mori, H. (CoI) & Fukuchi, M. (CoI)

  2014/04/01 → 2017/03/31

  Project: Research

• Novel anti-cancer mechanism of the targeting of the association between receptor-type sodium pump and VSOR channels

  Fujii, T. (PI)

  2014/04/01 → 2017/03/31

  Project: Research

• Exploration of tumor-promoting inflammatory immune responses and its application for cancer treatment

  Hayakawa, Y. (PI)

  2014/04/01 → 2017/03/31

  Project: Research

• ABC protein subfamily D: Mechanisms about subcellular localization and substrate transport, and regulation of cell function

  今中常雄 (Principal Investigator) & Kawaguchi, K. (Co-Investigator(Kenkyū-buntansha))

  Japan Society for the Promotion of Science

  2014/04/01 → 2017/03/31

  Project: Research Project

• Explore molecular basis underlying formation of chemical diversity in genus Panax through RNA-Seq analysis of three Panax species with different chemical compositions

  Zhu, S. (Principal Investigator)

  Japan Society for the Promotion of Science

  2014/04/01 → 2017/03/31

  Project: Research Project

• Natural Products Chemical Biology targeting Wnt signaling pathway modulation

  Toume, K. (PI)

  2013/04/01 → 2015/03/31

  Project: Research

• Anti-allergic effect of kakkonto by regulating intestinal mucosal immunity through the induction of regulatory T cells in the colon

  Yamamoto, T. (PI) & Hayashi, S. (CoI)

  2013/04/01 → 2016/03/31

  Project: Research

• インドールプレニル基転移酵素の動的立体構造基盤の確立と酵素触媒機能の拡張

  Morita, H. (PI)

  2013/04/01 → 2015/03/31

  Project: Research

• In vivo patch-clamp analysis of itch transmission in central nerve system

  Uta, D. (PI)

  2013/04/01 → 2015/03/31

  Project: Research

• Investigation of the immunological function of the NASH-inducing transplanted NKT, and drug discovery

  Koizumi, K. (PI)

  2013/04/01 → 2015/03/31

  Project: Research