Research output per year
Research output per year
Research output
- 1 - 50 out of 131 results
Search results
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2025
Analysis of the Fossilization Processes of Vicarya callosa japonica Shells Using Raman Micro-Mapping Combined with Principal Component Analysis and Partial Least Squares Regression
Tanaka, Y., Hashimoto, K., Ichiki, T., Sato, H., Ozaki, Y. & Tsuboi, M., 2025, (Accepted/In press) In: Applied Spectroscopy.Research output: Contribution to journal › Article › peer-review
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Identification of the Cellular Tipping Point in the Inflammation Model of LPS-Induced RAW264.7 Macrophages Through Raman Spectroscopy and the Dynamical Network Biomarker Theory
Taketani, A., Koshiyama, S., Haruki, T., Yonezawa, S., Tahara, J., Yamazaki, M., Oshima, Y., Wada, A., Sato, T., Koizumi, K., Kitajima, I. & Saito, S., 2025/02, In: Molecules. 30, 4, 920.Research output: Contribution to journal › Article › peer-review
Open Access -
Identifying the crucial tipping point in the maturation process of cultured neurons using Raman spectroscopy and a dynamic network biomarker (DNB) analysis
Hashimoto, K., Yonezawa, S., Haruki, T., Koizumi, K., Oshima, Y., Kitajima, I., Sato, H. & Saito, S., 2025/01, In: Biochemical and Biophysical Research Communications. 743, 151167.Research output: Contribution to journal › Article › peer-review
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Integration of Dynamical Network Biomarkers, Control Theory and Drosophila Model Identifies Vasa/DDX4 as the Potential Therapeutic Targets for Metabolic Syndrome
Akagi, K., Jin, Y. J., Koizumi, K., Oku, M., Ito, K., Shen, X., Imura, J. I., Aihara, K. & Saito, S., 2025/03, In: Cells. 14, 6, 415.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Re-Stabilizing Large-Scale Network Systems Using High-Dimension Low-Sample-Size Data Analysis
Shen, X., Sasahara, H., Imura, J. I., Oku, M. & Aihara, K., 2025, In: IEEE Transactions on Emerging Topics in Computational Intelligence. 9, 2, p. 1638-1649 12 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Study of N-Acetylamino Saccharides with Synchrotron-Based Ultraviolet Resonance Raman Spectroscopy: In Combination with ATR Far-Ultraviolet Spectroscopy
Hashimoto, K., Matroodi, F., Morimatsu, S., Rossi, B., Morisawa, Y., Ozaki, Y. & Sato, H., 2025/02/20, In: Journal of Physical Chemistry Letters. 16, 7, p. 1769-1778 10 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2024
Clarinet Plots: Alternative to Violin Plots to Display Zero-inflated Distribution of scRNA-seq Data
Oku, M., 2024/08/30, In: IPSJ Transactions on Bioinformatics. 17, p. 48 54 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Deletion of platelet-derived growth factor receptor β suppresses tumorigenesis in metabolic dysfunction-associated steatohepatitis (MASH) mice with diabetes
Wada, T., Takeda, Y., Okekawa, A., Komatsu, G., Iwasa, Y., Onogi, Y., Takasaki, I., Hamashima, T., Sasahara, M., Tsuneki, H. & Sasaoka, T., 2024/12, In: Scientific Reports. 14, 1, 23829.Research output: Contribution to journal › Article › peer-review
Open Access -
Establishing Monoclonal Gammopathy of Undetermined Significance as an Independent Pre-Disease State of Multiple Myeloma Using Raman Spectroscopy, Dynamical Network Biomarker Theory, and Energy Landscape Analysis
Yonezawa, S., Haruki, T., Koizumi, K., Taketani, A., Oshima, Y., Oku, M., Wada, A., Sato, T., Masuda, N., Tahara, J., Fujisawa, N., Koshiyama, S., Kadowaki, M., Kitajima, I. & Saito, S., 2024/02, In: International Journal of Molecular Sciences. 25, 3, 1570.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Indigenous gut microbiota constitutively drive release of ciliary neurotrophic factor from mucosal enteric glia to maintain the homeostasis of enteric neural circuits
Kato, R., Yamamoto, T., Ogata, H., Miyata, K., Hayashi, S., Gershon, M. D. & Kadowaki, M., 2024, In: Frontiers in Immunology. 15, 1372670.Research output: Contribution to journal › Article › peer-review
Open Access -
Neurodevelopmental Process Monitoring of Cytosine Arabinoside-Exposed Neurons Using Raman Spectroscopy
Hashimoto, K. & Sato, H., 2024, (Accepted/In press) In: Applied Spectroscopy.Research output: Contribution to journal › Article › peer-review
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Platelet-derived growth factor signaling in pericytes promotes hypothalamic inflammation and obesity
Okekawa, A., Wada, T., Onogi, Y., Takeda, Y., Miyazawa, Y., Sasahara, M., Tsuneki, H. & Sasaoka, T., 2024/12, In: Molecular Medicine. 30, 1, 21.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
2023
Allergic inflammation disrupts epithelial electrogenic electrolyte transport through cholinergic regulation in the mouse colon
Yamamoto, T., Katsuki, Y., Kanauchi, Y., Hayashi, S. & Kadowaki, M., 2023, In: Biomedical Research (Japan). 44, 1, p. 31-40 10 p.Research output: Contribution to journal › Article › peer-review
Open Access -
A transdermal treatment with MC903 ameliorates diet-induced obesity by reducing visceral fat and increasing myofiber thickness and energy consumption in mice
Wada, T., Miyazawa, Y., Ikurumi, M., Fuse, K., Okekawa, A., Onogi, Y., Saito, S., Tsuneki, H. & Sasaoka, T., 2023/12, In: Nutrition and Metabolism. 20, 1, 10.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Correction for Extrinsic Background in Raman Hyperspectral Images
Taylor, J. N., Pélissier, A., Mochizuki, K., Hashimoto, K., Kumamoto, Y., Harada, Y., Fujita, K., Bocklitz, T. & Komatsuzaki, T., 2023/08/22, In: Analytical Chemistry. 95, 33, p. 12298-12305 8 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Design of input assignment and feedback gain for re-stabilizing undirected networks with High-Dimension Low-Sample-Size data
Yasukata, H., Shen, X., Sasahara, H., Imura, J. I., Oku, M. & Aihara, K., 2023/08, In: International Journal of Robust and Nonlinear Control. 33, 12, p. 6734-6753 20 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Development of in-situ Raman diagnosis technique of eosinophil esophagitis
Zakaria, R., Andriana, B. B., Watanabe, T., Maryani, A., Paramitha, P. N., Kuntana, Y. P., Kusaka, Y., Noothalapati, H., Iwasaki, K., Oshima, N., Hashimoto, K., Matsuyoshi, H., Ishihara, S., Yamamoto, T. & Sato, H., 2023/01/15, In: Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy. 285, 121804.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Lipid droplet accumulation and adipophilin expression in follicular thyroid carcinoma
Hayakawa, M., Taylor, J. N., Nakao, R., Mochizuki, K., Sawai, Y., Hashimoto, K., Tabata, K., Kumamoto, Y., Fujita, K., Konishi, E., Hirano, S., Tanaka, H., Komatsuzaki, T. & Harada, Y., 2023/01/15, In: Biochemical and Biophysical Research Communications. 640, p. 192-201 10 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Model-Free Dominant Pole Placement for Restabilizing High-Dimensional Network Systems via Small-Sample-Size Data
Shen, X., Sasahara, H., Morishita, M., Imura, J. I., Oku, M. & Aihara, K., 2023, In: IEEE Access. 11, p. 45572-45585 14 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Reduced intestinal lipid absorption improves glucose metabolism in aged G2-Terc knockout mice
Liu, X., Khalil, A. E. M. M., Muthukumarasamy, U., Onogi, Y., Yan, X., Singh, I., Lopez-Gonzales, E., Israel, A., Serrano, A. C., Strowig, T. & Ussar, S., 2023/12, In: BMC biology. 21, 1, 150.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
2022
Application of the Dynamical Network Biomarker Theory to Raman Spectra
Haruki, T., Yonezawa, S., Koizumi, K., Yoshida, Y., Watanabe, T. M., Fujita, H., Oshima, Y., Oku, M., Taketani, A., Yamazaki, M., Ichimura, T., Kadowaki, M., Kitajima, I. & Saito, S., 2022/12, In: Biomolecules. 12, 12, 1730.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Hypothalamic orexin prevents non-alcoholic steatohepatitis and hepatocellular carcinoma in obesity
Tsuneki, H., Maeda, T., Takata, S., Sugiyama, M., Otsuka, K., Ishizuka, H., Onogi, Y., Tokai, E., Koshida, C., Kon, K., Takasaki, I., Hamashima, T., Sasahara, M., Rudich, A., Koya, D., Sakurai, T., Yanagisawa, M., Yamanaka, A., Wada, T. & Sasaoka, T., 2022/10/18, In: Cell Reports. 41, 3, 111497.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Intestinal epithelial BLT1 promotes mucosal repair
Hayashi, S., Muraleedharan, C. K., Oku, M., Tomar, S., Hogan, S. P., Quiros, M., Parkos, C. A. & Nusrat, A., 2022/12/08, In: JCI Insight. 7, 23, e162392.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
L-Serine Supplementation Blunts Fasting-Induced Weight Regain by Increasing Brown Fat Thermogenesis
López-Gonzales, E., Lehmann, L., Ruiz-Ojeda, F. J., Hernández-Bautista, R., Altun, I., Onogi, Y., Khalil, A. E., Liu, X., Israel, A. & Ussar, S., 2022/05/01, In: Nutrients. 14, 9, 1922.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
2021
Active integrins regulate white adipose tissue insulin sensitivity and brown fat thermogenesis
Ruiz-Ojeda, F. J., Wang, J., Bäcker, T., Krueger, M., Zamani, S., Rosowski, S., Gruber, T., Onogi, Y., Feuchtinger, A., Schulz, T. J., Fässler, R., Müller, T. D., García-Cáceres, C., Meier, M., Blüher, M. & Ussar, S., 2021/03, In: Molecular Metabolism. 45, 101147.Research output: Contribution to journal › Article › peer-review
Open Access40 Scopus citations -
Coherent Anti-Stokes Raman Scattering Spectroscopy Using a Double-Wavelength-Emission Electronically Tuned Ti:Sapphire Laser
Hirai, N., Maeda, Y., Hashimoto, K., Andriana, B. B., Matsuyoshi, H. & Sato, H., 2021/08, In: Applied Spectroscopy. 75, 8, p. 988-993 6 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Morphologies and distributions of 5-HT containing enteroendocrine cells in the mouse large intestine
Kuramoto, H., Koo, A., Fothergill, L. J., Hunne, B., Yoshimura, R., Kadowaki, M. & Furness, J. B., 2021/05, In: Cell and Tissue Research. 384, 2, p. 275-286 12 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Oestrogen receptor α in T cells controls the T cell immune profile and glucose metabolism in mouse models of gestational diabetes mellitus
Tanaka, T., Wada, T., Uno, K., Ogihara, S., Ie, H., Okekawa, A., Ishikawa, A., Ito, T., Miyazawa, Y., Sameshima, A., Onogi, Y., Tsuneki, H., Sasahara, M., Nakashima, A., Saito, S. & Sasaoka, T., 2021/07, In: Diabetologia. 64, 7, p. 1660-1673 14 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Pathophysiological roles of neuro-immune interactions between enteric neurons and mucosal mast cells in the gut of food allergy mice
Yashiro, T., Ogata, H., Zaidi, S. F., Lee, J., Hayashi, S., Yamamoto, T. & Kadowaki, M., 2021/07, In: Cells. 10, 7, 1586.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
Suppression of plasmacytoid dendritic cell migration to colonic isolated lymphoid follicles abrogates the development of colitis
Zhang, Y., Yamamoto, T., Hayashi, S. & Kadowaki, M., 2021/09, In: Biomedicine and Pharmacotherapy. 141, 111881.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
2020
Astaxanthin stimulates mitochondrial biogenesis in insulin resistant muscle via activation of AMPK pathway
Nishida, Y., Nawaz, A., Kado, T., Takikawa, A., Igarashi, Y., Onogi, Y., Wada, T., Sasaoka, T., Yamamoto, S., Sasahara, M., Imura, J., Tokuyama, K., Usui, I., Nakagawa, T., Fujisaka, S., Kunimasa, Y. & Tobe, K., 2020/02/01, In: Journal of Cachexia, Sarcopenia and Muscle. 11, 1, p. 241-258 18 p.Research output: Contribution to journal › Article › peer-review
Open Access116 Scopus citations -
Estrogen regulates sex-specific localization of regulatory T cells in adipose tissue of obese female mice
Ishikawa, A., Wada, T., Nishimura, S., Ito, T., Okekawa, A., Onogi, Y., Watanabe, E., Sameshima, A., Tanaka, T., Tsuneki, H., Saito, S. & Sasaoka, T., 2020, In: PLoS ONE. 15, 4, e0230885.Research output: Contribution to journal › Article › peer-review
Open Access32 Scopus citations -
Ginger increases aldh1a1 expression and enhances retinoic acid signaling in a human colonic epithelial cell line
Nagata, Y., Yamamoto, T. & Kadowaki, M., 2020, In: Journal of Nutritional Science and Vitaminology. 66, 5, p. 462-467 6 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Interleukin-4 Receptor α Subunit Deficiency Alleviates Murine Intestinal Inflammation In Vivo Through the Enhancement of Intestinal Mucosal Barrier Function
Hertati, A., Hayashi, S., Ogawa, Y., Yamamoto, T. & Kadowaki, M., 2020/10/28, In: Frontiers in Pharmacology. 11, 573470.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Isoflavones suppress cyp26b1 expression in the murine colonic lamina propria
Yamamoto, T., Nagata, Y., Hayashi, S. & Kadowaki, M., 2020/12/01, In: Biological and Pharmaceutical Bulletin. 43, 12, p. 1945-1949 5 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Morphological elucidation of short-chain fatty acid receptor GPR41-positive enteric sensory neurons in the colon of mice with dextran sulfate sodium-induced colitis
Hertati, A., Hayashi, S., Ogata, H., Miyata, K., Kato, R., Yamamoto, T. & Kadowaki, M., 2020/12, In: Heliyon. 6, 12, e05647.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Pro-inflammatory macrophages coupled with glycolysis remodel adipose vasculature by producing platelet-derived growth factor-B in obesity
Onogi, Y., Wada, T., Okekawa, A., Matsuzawa, T., Watanabe, E., Ikeda, K., Nakano, M., Kitada, M., Koya, D., Tsuneki, H. & Sasaoka, T., 2020/12/01, In: Scientific Reports. 10, 1, 670.Research output: Contribution to journal › Article › peer-review
Open Access25 Scopus citations -
Stromal cell-derived factor 1 (SDF1) attenuates platelet-derived growth factor-B (PDGF-B)-induced vascular remodeling for adipose tissue expansion in obesity
Watanabe, E., Wada, T., Okekawa, A., Kitamura, F., Komatsu, G., Onogi, Y., Yamamoto, S., Sasahara, M., Kitada, M., Koya, D., Tsuneki, H. & Sasaoka, T., 2020/11/01, In: Angiogenesis. 23, 4, p. 667-684 18 p.Research output: Contribution to journal › Article › peer-review
24 Scopus citations -
Suppression of Dynamical Network Biomarker Signals at the Predisease State (Mibyou) before Metabolic Syndrome in Mice by a Traditional Japanese Medicine (Kampo Formula) Bofutsushosan
Koizumi, K., Oku, M., Hayashi, S., Inujima, A., Shibahara, N., Chen, L., Igarashi, Y., Tobe, K., Saito, S., Kadowaki, M. & Aihara, K., 2020, In: Evidence-based Complementary and Alternative Medicine. 2020, 9129134.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
Therapeutic benefit in allergic dermatitis derived from the inhibitory effect of byakkokaninjinto on the migration of plasmacytoid dendritic cells
Yamamoto, T., Zhang, Y., Kigasawa, A., Hayashi, S. & Kadowaki, M., 2020, In: Evidence-based Complementary and Alternative Medicine. 2020, 9532475.Research output: Contribution to journal › Article › peer-review
Open Access -
2019
Identifying pre-disease signals before metabolic syndrome in mice by dynamical network biomarkers
Koizumi, K., Oku, M., Hayashi, S., Inujima, A., Shibahara, N., Chen, L., Igarashi, Y., Tobe, K., Saito, S., Kadowaki, M. & Aihara, K., 2019/12/01, In: Scientific Reports. 9, 1, 8767.Research output: Contribution to journal › Article › peer-review
Open Access44 Scopus citations -
Regional variations in the number distribution of intrinsic myenteric neurons and coinnervated motor endplates on the striated muscles in the rat esophagus
Kuramoto, H., Yoshimura, R., Sakamoto, H. & Kadowaki, M., 2019/07, In: Autonomic Neuroscience: Basic and Clinical. 219, p. 25-32 8 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
The isoflavone puerarin induces Foxp3+ regulatory T cells by augmenting retinoic acid production, thereby inducing mucosal immune tolerance in a murine food allergy model
Yamamoto, T., Matsunami, E., Komori, K., Hayashi, S. & Kadowaki, M., 2019/08/27, In: Biochemical and Biophysical Research Communications. 516, 3, p. 626-631 6 p.Research output: Contribution to journal › Article › peer-review
19 Scopus citations -
2018
Discovery of a sugar-based nanoparticle universally existing in boiling herbal water extracts and their immunostimulant effect
Iitsuka, H., Koizumi, K., Inujima, A., Suzaki, M., Mizuno, Y., Takeshita, Y., Eto, T., Otsuka, Y., Shimada, R., Liu, M., Ikeda, K., Nakano, M., Suzuki, R., Maruyama, K., Zhou, Y., Sakurai, H. & Shibahara, N., 2018/12, In: Biochemistry and Biophysics Reports. 16, p. 62-68 7 p.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
Discrimination analysis of excitatory and inhibitory neurons using Raman spectroscopy
Hashimoto, K., Andriana, B. B., Matsuyoshi, H. & Sato, H., 2018/06/21, In: Analyst. 143, 12, p. 2889-2894 6 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
Early detection of virus infection in live human cells using Raman spectroscopy
Moor, K., Terada, Y., Taketani, A., Matsuyoshi, H., Ohtani, K. & Sato, H., 2018/09/01, In: Journal of Biomedical Optics. 23, 9, 097001.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
KampoDB, database of predicted targets and functional annotations of natural medicines
Sawada, R., Iwata, M., Umezaki, M., Usui, Y., Kobayashi, T., Kubono, T., Hayashi, S., Kadowaki, M. & Yamanishi, Y., 2018/12/01, In: Scientific Reports. 8, 1, 11216.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
Partial depletion of CD206-positive M2-like macrophages induces proliferation of beige progenitors and enhances browning after cold stimulation
Igarashi, Y., Nawaz, A., Kado, T., Bilal, M., Kuwano, T., Yamamoto, S., Sasahara, M., Jiuxiang, X., Inujima, A., Koizumi, K., Imura, J., Shibahara, N., Usui, I., Fujisaka, S. & Tobe, K., 2018/12/01, In: Scientific Reports. 8, 1, 14567.Research output: Contribution to journal › Article › peer-review
Open Access27 Scopus citations -
2017
Elimination of spiral waves in a locally connected chaotic neural network by a dynamic phase space constraint
Li, Y., Oku, M., He, G. & Aihara, K., 2017/04/01, In: Neural Networks. 88, p. 9-21 13 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Eplerenone prevented obesity-induced inflammasome activation and glucose intolerance
Wada, T., Ishikawa, A., Watanabe, E., Nakamura, Y., Aruga, Y., Hasegawa, H., Onogi, Y., Honda, H., Nagai, Y., Takatsu, K., Ishii, Y., Sasahara, M., Koya, D., Tsuneki, H. & Sasaoka, T., 2017/12/01, In: Journal of Endocrinology. 235, 3, p. 179-191 13 p.Research output: Contribution to journal › Article › peer-review
Open Access51 Scopus citations