年別の研究成果
年別の研究成果
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2025
Analysis of the Fossilization Processes of Vicarya callosa japonica Shells Using Raman Micro-Mapping Combined with Principal Component Analysis and Partial Least Squares Regression
Tanaka, Y., Hashimoto, K., Ichiki, T., Sato, H., Ozaki, Y. & Tsuboi, M., 2025, (受理済み/印刷中) In: Applied Spectroscopy.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
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Characterization of bone marrow cells for prognosis prediction of multiple myeloma using Raman spectroscopy with optimal discriminant model
Oshima, Y., Taketani, A., Yonezawa, S., Haruki, T., Wada, A., Sato, T. & Koizumi, K., 2025, Optical Biopsy XXIII: Toward Real-Time Spectroscopic Imaging and Diagnosis. Alfano, R. R., Seddon, A. B., Shi, L. & Wu, B. (eds.). SPIE, 1331102. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 13311).研究成果: 書籍の章/レポート/会議録 › 会議への寄与 › 査読
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Identification of the Cellular Tipping Point in the Inflammation Model of LPS-Induced RAW264.7 Macrophages Through Raman Spectroscopy and the Dynamical Network Biomarker Theory
Taketani, A., Koshiyama, S., Haruki, T., Yonezawa, S., Tahara, J., Yamazaki, M., Oshima, Y., Wada, A., Sato, T., Koizumi, K., Kitajima, I. & Saito, S., 2025/02, In: Molecules. 30, 4, 920.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
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Identifying the crucial tipping point in the maturation process of cultured neurons using Raman spectroscopy and a dynamic network biomarker (DNB) analysis
Hashimoto, K., Yonezawa, S., Haruki, T., Koizumi, K., Oshima, Y., Kitajima, I., Sato, H. & Saito, S., 2025/01, In: Biochemical and Biophysical Research Communications. 743, 151167.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
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Integration of Dynamical Network Biomarkers, Control Theory and Drosophila Model Identifies Vasa/DDX4 as the Potential Therapeutic Targets for Metabolic Syndrome
Akagi, K., Jin, Y. J., Koizumi, K., Oku, M., Ito, K., Shen, X., Imura, J. I., Aihara, K. & Saito, S., 2025/03, In: Cells. 14, 6, 415.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access1 被引用数 (Scopus) -
Re-Stabilizing Large-Scale Network Systems Using High-Dimension Low-Sample-Size Data Analysis
Shen, X., Sasahara, H., Imura, J. I., Oku, M. & Aihara, K., 2025, In: IEEE Transactions on Emerging Topics in Computational Intelligence. 9, 2, p. 1638-1649 12 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
1 被引用数 (Scopus) -
Study of N-Acetylamino Saccharides with Synchrotron-Based Ultraviolet Resonance Raman Spectroscopy: In Combination with ATR Far-Ultraviolet Spectroscopy
Hashimoto, K., Matroodi, F., Morimatsu, S., Rossi, B., Morisawa, Y., Ozaki, Y. & Sato, H., 2025/02/20, In: Journal of Physical Chemistry Letters. 16, 7, p. 1769-1778 10 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
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2024
Clarinet Plots: Alternative to Violin Plots to Display Zero-inflated Distribution of scRNA-seq Data
Oku, M., 2024/08/30, In: IPSJ Transactions on Bioinformatics. 17, p. 48 54 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access -
Deletion of platelet-derived growth factor receptor β suppresses tumorigenesis in metabolic dysfunction-associated steatohepatitis (MASH) mice with diabetes
Wada, T., Takeda, Y., Okekawa, A., Komatsu, G., Iwasa, Y., Onogi, Y., Takasaki, I., Hamashima, T., Sasahara, M., Tsuneki, H. & Sasaoka, T., 2024/12, In: Scientific Reports. 14, 1, 23829.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
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Establishing Monoclonal Gammopathy of Undetermined Significance as an Independent Pre-Disease State of Multiple Myeloma Using Raman Spectroscopy, Dynamical Network Biomarker Theory, and Energy Landscape Analysis
Yonezawa, S., Haruki, T., Koizumi, K., Taketani, A., Oshima, Y., Oku, M., Wada, A., Sato, T., Masuda, N., Tahara, J., Fujisawa, N., Koshiyama, S., Kadowaki, M., Kitajima, I. & Saito, S., 2024/02, In: International Journal of Molecular Sciences. 25, 3, 1570.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access5 被引用数 (Scopus) -
Indigenous gut microbiota constitutively drive release of ciliary neurotrophic factor from mucosal enteric glia to maintain the homeostasis of enteric neural circuits
Kato, R., Yamamoto, T., Ogata, H., Miyata, K., Hayashi, S., Gershon, M. D. & Kadowaki, M., 2024, In: Frontiers in Immunology. 15, 1372670.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
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Neurodevelopmental Process Monitoring of Cytosine Arabinoside-Exposed Neurons Using Raman Spectroscopy
Hashimoto, K. & Sato, H., 2024, (受理済み/印刷中) In: Applied Spectroscopy.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
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Platelet-derived growth factor signaling in pericytes promotes hypothalamic inflammation and obesity
Okekawa, A., Wada, T., Onogi, Y., Takeda, Y., Miyazawa, Y., Sasahara, M., Tsuneki, H. & Sasaoka, T., 2024/12, In: Molecular Medicine. 30, 1, 21.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access4 被引用数 (Scopus) -
ラマン分光法の臨床応用と未病状態の検出に向けた取り組み
Oshima, Y., Haruki, T., Yonezawa, S., Taketani, A., Koizumi, K. & Katagiri, T., 2024/06/20, In: レーザー研究. 52, 6, p. 298 302 p.研究成果: ジャーナルへの寄稿 › 総説
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2023
Allergic inflammation disrupts epithelial electrogenic electrolyte transport through cholinergic regulation in the mouse colon
Yamamoto, T., Katsuki, Y., Kanauchi, Y., Hayashi, S. & Kadowaki, M., 2023, In: Biomedical Research (Japan). 44, 1, p. 31-40 10 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access -
A transdermal treatment with MC903 ameliorates diet-induced obesity by reducing visceral fat and increasing myofiber thickness and energy consumption in mice
Wada, T., Miyazawa, Y., Ikurumi, M., Fuse, K., Okekawa, A., Onogi, Y., Saito, S., Tsuneki, H. & Sasaoka, T., 2023/12, In: Nutrition and Metabolism. 20, 1, 10.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access2 被引用数 (Scopus) -
Correction for Extrinsic Background in Raman Hyperspectral Images
Taylor, J. N., Pélissier, A., Mochizuki, K., Hashimoto, K., Kumamoto, Y., Harada, Y., Fujita, K., Bocklitz, T. & Komatsuzaki, T., 2023/08/22, In: Analytical Chemistry. 95, 33, p. 12298-12305 8 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access2 被引用数 (Scopus) -
Data-Driven Re-stabilization of Gene Regulatory Network Towards Early Medical Treatment
Shen, X., Sasahara, H., Imura, J. I., Oku, M. & Aihara, K., 2023/07/01, IFAC-PapersOnLine. Ishii, H., Ebihara, Y., Imura, J.-I. & Yamakita, M. (eds.). 2 ed. Elsevier B.V., p. 6200-6205 6 p. (IFAC-PapersOnLine; vol. 56, no. 2).研究成果: 書籍の章/レポート/会議録 › 会議への寄与 › 査読
Open Access2 被引用数 (Scopus) -
Design of input assignment and feedback gain for re-stabilizing undirected networks with High-Dimension Low-Sample-Size data
Yasukata, H., Shen, X., Sasahara, H., Imura, J. I., Oku, M. & Aihara, K., 2023/08, In: International Journal of Robust and Nonlinear Control. 33, 12, p. 6734-6753 20 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access2 被引用数 (Scopus) -
Development of in-situ Raman diagnosis technique of eosinophil esophagitis
Zakaria, R., Andriana, B. B., Watanabe, T., Maryani, A., Paramitha, P. N., Kuntana, Y. P., Kusaka, Y., Noothalapati, H., Iwasaki, K., Oshima, N., Hashimoto, K., Matsuyoshi, H., Ishihara, S., Yamamoto, T. & Sato, H., 2023/01/15, In: Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy. 285, 121804.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access3 被引用数 (Scopus) -
Lipid droplet accumulation and adipophilin expression in follicular thyroid carcinoma
Hayakawa, M., Taylor, J. N., Nakao, R., Mochizuki, K., Sawai, Y., Hashimoto, K., Tabata, K., Kumamoto, Y., Fujita, K., Konishi, E., Hirano, S., Tanaka, H., Komatsuzaki, T. & Harada, Y., 2023/01/15, In: Biochemical and Biophysical Research Communications. 640, p. 192-201 10 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access3 被引用数 (Scopus) -
Model-Free Dominant Pole Placement for Restabilizing High-Dimensional Network Systems via Small-Sample-Size Data
Shen, X., Sasahara, H., Morishita, M., Imura, J. I., Oku, M. & Aihara, K., 2023, In: IEEE Access. 11, p. 45572-45585 14 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access3 被引用数 (Scopus) -
New Possibilities for Evaluating the Development of Age-Related Pathologies Using the Dynamical Network Biomarkers Theory
Akagi, K., Koizumi, K., Kadowaki, M., Kitajima, I. & Saito, S., 2023/09, In: Cells. 12, 18, 2297.研究成果: ジャーナルへの寄稿 › 総説 › 査読
Open Access2 被引用数 (Scopus) -
Practices, Potential, and Perspectives for Detecting Predisease Using Raman Spectroscopy
Oshima, Y., Haruki, T., Koizumi, K., Yonezawa, S., Taketani, A., Kadowaki, M. & Saito, S., 2023/08, In: International Journal of Molecular Sciences. 24, 15, 12170.研究成果: ジャーナルへの寄稿 › 総説 › 査読
Open Access9 被引用数 (Scopus) -
Pre-disease Detection Using Dynamical Network Biomarkers in Gene Regulatory Networks with Cell-to-cell Interaction
Saito, Y., Sasahara, H., Shen, X., Peña Ramirez, J., Imura, J., Oku, M. & Aihara, K., 2023/07/01, IFAC-PapersOnLine. Ishii, H., Ebihara, Y., Imura, J.-I. & Yamakita, M. (eds.). 2 ed. Elsevier B.V., p. 6459-6464 6 p. (IFAC-PapersOnLine; vol. 56, no. 2).研究成果: 書籍の章/レポート/会議録 › 会議への寄与 › 査読
Open Access1 被引用数 (Scopus) -
Reduced intestinal lipid absorption improves glucose metabolism in aged G2-Terc knockout mice
Liu, X., Khalil, A. E. M. M., Muthukumarasamy, U., Onogi, Y., Yan, X., Singh, I., Lopez-Gonzales, E., Israel, A., Serrano, A. C., Strowig, T. & Ussar, S., 2023/12, In: BMC biology. 21, 1, 150.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access2 被引用数 (Scopus) -
データ駆動型アプローチによる未病の解明
Haruki, T., Koizumi, K., Yonezawa, S., Oku, M., Oshima, Y., Hayashi, S., Watanabe, T. M., Kadowaki, M. & Saito, S., 2023/10/31, In: 基礎老化研究. 47, 3, p. 35 41 p.研究成果: ジャーナルへの寄稿 › 総説
Open Access -
未病研究の最前線
Saito, S., Haruki, T., Yonezawa, S., Oshima, Y., Kadowaki, M. & Koizumi, K., 2023/04/15, In: 生体の科学. 74, 2, p. 129 133 p.研究成果: ジャーナルへの寄稿 › 総説
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2022
Application of the Dynamical Network Biomarker Theory to Raman Spectra
Haruki, T., Yonezawa, S., Koizumi, K., Yoshida, Y., Watanabe, T. M., Fujita, H., Oshima, Y., Oku, M., Taketani, A., Yamazaki, M., Ichimura, T., Kadowaki, M., Kitajima, I. & Saito, S., 2022/12, In: Biomolecules. 12, 12, 1730.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
7 被引用数 (Scopus) -
Control of actin polymerization via reactive oxygen species generation using light or radiation
Ishimoto, T. & Mori, H., 2022, In: Frontiers in Cell and Developmental Biology. 10, p. 1014008研究成果: ジャーナルへの寄稿 › 総説 › 査読
8 被引用数 (Scopus) -
Hypothalamic orexin prevents non-alcoholic steatohepatitis and hepatocellular carcinoma in obesity
Tsuneki, H., Maeda, T., Takata, S., Sugiyama, M., Otsuka, K., Ishizuka, H., Onogi, Y., Tokai, E., Koshida, C., Kon, K., Takasaki, I., Hamashima, T., Sasahara, M., Rudich, A., Koya, D., Sakurai, T., Yanagisawa, M., Yamanaka, A., Wada, T. & Sasaoka, T., 2022/10/18, In: Cell Reports. 41, 3, 111497.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access16 被引用数 (Scopus) -
Intestinal epithelial BLT1 promotes mucosal repair
Hayashi, S., Muraleedharan, C. K., Oku, M., Tomar, S., Hogan, S. P., Quiros, M., Parkos, C. A. & Nusrat, A., 2022/12/08, In: JCI Insight. 7, 23, e162392.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
6 被引用数 (Scopus) -
Is epiploic fat the dermal fat of the intestine?
Onogi, Y. & Ussar, S., 2022/11, In: Gut. 71, 11, p. 2147-2148 2 p.研究成果: ジャーナルへの寄稿 › コメント/討論
3 被引用数 (Scopus) -
Low-Sample-Size Data-Driven Re-stabilization of Gene Network Systems
Shen, X., Morishita, M., Imura, J. I., Oku, M. & Aihara, K., 2022, In: IFAC Proceedings Volumes (IFAC-PapersOnline). 55, 25, p. 241-246 6 p.研究成果: ジャーナルへの寄稿 › 会議記事 › 査読
Open Access11 被引用数 (Scopus) -
L-Serine Supplementation Blunts Fasting-Induced Weight Regain by Increasing Brown Fat Thermogenesis
López-Gonzales, E., Lehmann, L., Ruiz-Ojeda, F. J., Hernández-Bautista, R., Altun, I., Onogi, Y., Khalil, A. E., Liu, X., Israel, A. & Ussar, S., 2022/05/01, In: Nutrients. 14, 9, 1922.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access8 被引用数 (Scopus) -
Neuro-immune crosstalk and food allergy: Focus on enteric neurons and mucosal mast cells
Kadowaki, M., Yamamoto, T. & Hayashi, S., 2022/07, In: Allergology International. 71, 3, p. 278-287 10 p.研究成果: ジャーナルへの寄稿 › 総説 › 査読
Open Access9 被引用数 (Scopus) -
Rapid and non-labelling detection method in food safety and adulteration
Andriana, B. B., Paramitha, P. N., Zakaria, R., Parikesit, P., Hashimoto, K. & Sato, H., 2022/02/15, In: IOP Conference Series: Earth and Environmental Science. 980, 1, 012049.研究成果: ジャーナルへの寄稿 › 会議記事 › 査読
Open Access2 被引用数 (Scopus) -
Regulatory networks determining substrate utilization in brown adipocytes
Onogi, Y. & Ussar, S., 2022/07, In: Trends in Endocrinology and Metabolism. 33, 7, p. 493-506 14 p.研究成果: ジャーナルへの寄稿 › 総説 › 査読
6 被引用数 (Scopus) -
2021
Active integrins regulate white adipose tissue insulin sensitivity and brown fat thermogenesis
Ruiz-Ojeda, F. J., Wang, J., Bäcker, T., Krueger, M., Zamani, S., Rosowski, S., Gruber, T., Onogi, Y., Feuchtinger, A., Schulz, T. J., Fässler, R., Müller, T. D., García-Cáceres, C., Meier, M., Blüher, M. & Ussar, S., 2021/03, In: Molecular Metabolism. 45, 101147.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access40 被引用数 (Scopus) -
Coherent Anti-Stokes Raman Scattering Spectroscopy Using a Double-Wavelength-Emission Electronically Tuned Ti:Sapphire Laser
Hirai, N., Maeda, Y., Hashimoto, K., Andriana, B. B., Matsuyoshi, H. & Sato, H., 2021/08, In: Applied Spectroscopy. 75, 8, p. 988-993 6 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
2 被引用数 (Scopus) -
Erratum: Suppression of dynamical network biomarker signals at the predisease state (Mibyou) before metabolic syndrome in mice by a traditional Japanese medicine (Kampo Formula) bofutsushosan (Evidence-Based Complementary and Alternative Medicine (2020) 2020 (9129134) DOI: 10.1155/2020/9129134)
Koizumi, K., Oku, M., Hayashi, S., Inujima, A., Shibahara, N., Chen, L., Igarashi, Y., Tobe, K., Saito, S., Kadowaki, M. & Aihara, K., 2021, In: Evidence-based Complementary and Alternative Medicine. 2021, 9760307.研究成果: ジャーナルへの寄稿 › コメント/討論
Open Access -
Morphologies and distributions of 5-HT containing enteroendocrine cells in the mouse large intestine
Kuramoto, H., Koo, A., Fothergill, L. J., Hunne, B., Yoshimura, R., Kadowaki, M. & Furness, J. B., 2021/05, In: Cell and Tissue Research. 384, 2, p. 275-286 12 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
13 被引用数 (Scopus) -
Oestrogen receptor α in T cells controls the T cell immune profile and glucose metabolism in mouse models of gestational diabetes mellitus
Tanaka, T., Wada, T., Uno, K., Ogihara, S., Ie, H., Okekawa, A., Ishikawa, A., Ito, T., Miyazawa, Y., Sameshima, A., Onogi, Y., Tsuneki, H., Sasahara, M., Nakashima, A., Saito, S. & Sasaoka, T., 2021/07, In: Diabetologia. 64, 7, p. 1660-1673 14 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access10 被引用数 (Scopus) -
Pathophysiological roles of neuro-immune interactions between enteric neurons and mucosal mast cells in the gut of food allergy mice
Yashiro, T., Ogata, H., Zaidi, S. F., Lee, J., Hayashi, S., Yamamoto, T. & Kadowaki, M., 2021/07, In: Cells. 10, 7, 1586.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access15 被引用数 (Scopus) -
Suppression of plasmacytoid dendritic cell migration to colonic isolated lymphoid follicles abrogates the development of colitis
Zhang, Y., Yamamoto, T., Hayashi, S. & Kadowaki, M., 2021/09, In: Biomedicine and Pharmacotherapy. 141, 111881.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access10 被引用数 (Scopus) -
2020
Astaxanthin stimulates mitochondrial biogenesis in insulin resistant muscle via activation of AMPK pathway
Nishida, Y., Nawaz, A., Kado, T., Takikawa, A., Igarashi, Y., Onogi, Y., Wada, T., Sasaoka, T., Yamamoto, S., Sasahara, M., Imura, J., Tokuyama, K., Usui, I., Nakagawa, T., Fujisaka, S., Kunimasa, Y. & Tobe, K., 2020/02/01, In: Journal of Cachexia, Sarcopenia and Muscle. 11, 1, p. 241-258 18 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access116 被引用数 (Scopus) -
Estrogen regulates sex-specific localization of regulatory T cells in adipose tissue of obese female mice
Ishikawa, A., Wada, T., Nishimura, S., Ito, T., Okekawa, A., Onogi, Y., Watanabe, E., Sameshima, A., Tanaka, T., Tsuneki, H., Saito, S. & Sasaoka, T., 2020, In: PLoS ONE. 15, 4, e0230885.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access32 被引用数 (Scopus) -
Ginger increases aldh1a1 expression and enhances retinoic acid signaling in a human colonic epithelial cell line
Nagata, Y., Yamamoto, T. & Kadowaki, M., 2020, In: Journal of Nutritional Science and Vitaminology. 66, 5, p. 462-467 6 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access4 被引用数 (Scopus) -
Interleukin-4 Receptor α Subunit Deficiency Alleviates Murine Intestinal Inflammation In Vivo Through the Enhancement of Intestinal Mucosal Barrier Function
Hertati, A., Hayashi, S., Ogawa, Y., Yamamoto, T. & Kadowaki, M., 2020/10/28, In: Frontiers in Pharmacology. 11, 573470.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access12 被引用数 (Scopus) -
Isoflavones suppress cyp26b1 expression in the murine colonic lamina propria
Yamamoto, T., Nagata, Y., Hayashi, S. & Kadowaki, M., 2020/12/01, In: Biological and Pharmaceutical Bulletin. 43, 12, p. 1945-1949 5 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access4 被引用数 (Scopus)