Characterization of bone marrow cells for prognosis prediction of multiple myeloma using Raman spectroscopy with optimal discriminant model

研究成果: 書籍の章/レポート/会議録会議への寄与査読

抄録

Multiple Myeloma (MM) is a disease characterized by an increase in cancerous plasma cells, known as myeloma cells, which have differentiated from B cells and primarily reside in bone marrow. It usually develops from an asymptomatic precursor state, Monoclonal Gammopathy of Undetermined Significance (MGUS). MM generally has a poor prognosis. To distinguish Multiple Myeloma from its precursor state, which requires treatment, a comprehensive diagnosis is made through detailed examination of blood, urine, and bone marrow. The incidence of these diseases is known to increase with age. In this study, we propose a new diagnostic method for MM patients using Raman spectroscopy. This technique utilizes the interaction of light to obtain information on the molecular without labeling. Since it can be used in combination with conventional histopathological diagnosis through staining, this could lead to the development of models that are useful for clinical decision-making.

本文言語英語
ホスト出版物のタイトルOptical Biopsy XXIII
ホスト出版物のサブタイトルToward Real-Time Spectroscopic Imaging and Diagnosis
編集者Robert R. Alfano, Angela B. Seddon, Lingyan Shi, Binlin Wu
出版社SPIE
ISBN(電子版)9781510683709
DOI
出版ステータス出版済み - 2025
イベントOptical Biopsy XXIII: Toward Real-Time Spectroscopic Imaging and Diagnosis 2025 - San Francisco, 米国
継続期間: 2025/01/272025/01/29

出版物シリーズ

名前Progress in Biomedical Optics and Imaging - Proceedings of SPIE
13311
ISSN(印刷版)1605-7422

学会

学会Optical Biopsy XXIII: Toward Real-Time Spectroscopic Imaging and Diagnosis 2025
国/地域米国
CitySan Francisco
Period2025/01/272025/01/29

ASJC Scopus 主題領域

  • 電子材料、光学材料、および磁性材料
  • 原子分子物理学および光学
  • 生体材料
  • 放射線学、核医学およびイメージング

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