Projects per year
Personal profile
Campus career
医学科 助教 2011/01/01-2019/09/30
環境生体防御医学系 助教 2011/01/01-2019/09/30
医学系 助教 2019/10/01-
医学科 助教 2019/10/01-
医学部医学科 基幹教員
学部運営への参画状況・・・有-教授会
担当授業科目に係る状況・・・主要授業科目担当
環境生体防御医学系 助教 2011/01/01-2019/09/30
医学系 助教 2019/10/01-
医学科 助教 2019/10/01-
医学部医学科 基幹教員
学部運営への参画状況・・・有-教授会
担当授業科目に係る状況・・・主要授業科目担当
Research interests
抗原特異的T細胞の1個1個からT細胞のセンサーであるT細胞受容体遺伝子をクローニングし,その遺伝子の抗原特異性を評価するまでを10日間という極めて短期間で行うシステムを確立した.このシステムを用い,新たながんや感染症の治療法の開発を行っている.
Research Fields, Keywords
- Immunology
Field of expertise (Grants-in-aid for Scientific Research classification)
- Immunology
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Collaborations and top research areas from the last five years
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Projects
- 6 Finished
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Identification of antigens of tumor-infiltrated regulatory T cells and analysis of tumor suppression systems based on the antigens
Kobayashi, E. (PI)
2018/04/01 → 2021/03/31
Project: Research
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Development of Zika fever- and AIDS-peptide vaccine using next generation chip, T-ISAAC
Muraguchi, A. (PI), Kishi, H. (CoI), Ozawa, T. (CoI), Kobayashi, E. (CoI) & Udaka, K. (CoI)
2017/04/01 → 2020/03/31
Project: Research
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Development of an innovative lymphocyte chip to establish personalized immuno-therapy for infectious diseases
Muraguchi, A. (PI), Kishi, H. (CoI), Ozawa, T. (CoI), Hamana, H. (CoI) & Kobayashi, E. (CoI)
2014/04/01 → 2017/03/31
Project: Research
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Development of therapeutic hepatitis peptide vaccine using a novel T cell receptor cloning system
Kobayashi, E. (PI)
2012/04/01 → 2014/03/31
Project: Research
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Characterization of Tumor-Infiltrating Lymphocyte-Derived Atypical TCRs Recognizing Breast Cancer in an MR1-Dependent Manner
Hayee, A., Kobayashi, E., Motozono, C., Hamana, H., My, H. T. V., Okada, T., Toyooka, N., Yamaguchi, S., Ozawa, T. & Kishi, H., 2024/10, In: Cells. 13, 20, 1711.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Parsing digital or analog TCR performance through piconewton forces
Akitsu, A., Kobayashi, E., Feng, Y., Stephens, H. M., Brazin, K. N., Masi, D. J., Kirkpatrick, E. H., Mallis, R. J., Duke-Cohan, J. S., Booker, M. A., Cinella, V., Feng, W. W., Holliday, E. L., Lee, J. J., Zienkiewicz, K. J., Tolstorukov, M. Y., Hwang, W., Lang, M. J. & Reinherz, E. L., 2024/08, In: Science Advances. 10, 33, ado4313.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Development of a Novel CD26-Targeted Chimeric Antigen Receptor T-Cell Therapy for CD26-Expressing T-Cell Malignancies
Kobayashi, E., Kamihara, Y., Arai, M., Wada, A., Kikuchi, S., Hatano, R., Iwao, N., Susukida, T., Ozawa, T., Adachi, Y., Kishi, H., Dang, N. H., Yamada, T., Hayakawa, Y., Morimoto, C. & Sato, T., 2023/08, In: Cells. 12, 16, 2059.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Selection of highly responsive T cell receptors by an analysis combining the expression of multiple markers
Thi Viet Ha, M., Hamana, H., Shitaoka, K., Hayee, A., Kobayashi, E., Yoshikawa, T., Nakatsura, T., Saikawa, R., Sato, E., Osawa, M., Hitoshi, Y., Son Dang, T., Ozawa, T. & Kishi, H., 2023/06, In: Cancer Science. 114, 6, p. 2254-2264 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Rapid cloning of antigen-specific T-cell receptors by leveraging the cis activation of T cells
Kobayashi, E., Jin, A., Hamana, H., Shitaoka, K., Tajiri, K., Kusano, S., Yokoyama, S., Ozawa, T., Obata, T., Muraguchi, A. & Kishi, H., 2022/07, In: Nature Biomedical Engineering. 6, 7, p. 806-818 13 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations