Research output per year
Research output per year
Research output
Search results
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2025
Enhanced Production of Rebaudioside D and Rebaudioside M through V155T Substitution in the Glycosyltransferase UGT91D2 from Stevia rebaudiana
Shoji, T., Tanaka, Y., Nakashima, Y., Mizohata, E., Komaki, M., Sugawara, S., Takaya, J., Yonekura-Sakakibara, K., Morita, H., Saito, K. & Hirai, T., 2025/01/22, In: Journal of Agricultural and Food Chemistry. 73, 3, p. 2019-2032 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2024
A transcription factor of SHI family AaSHI1 activates artemisinin biosynthesis genes in Artemisia annua
Yang, Y., Li, Y., Jin, L., Li, P., Zhou, Q., Sheng, M., Ma, X., Shoji, T., Hao, X. & Kai, G., 2024/12, In: BMC Genomics. 25, 1, 776.Research output: Contribution to journal › Article › peer-review
Open Access -
Disruption of CYP88B1 by transcription activator-like effector nuclease in potato and potential use to produce useful saponins
Yasumoto, S., Lee, H. J., Akiyama, R., Sawai, S., Mizutani, M., Umemoto, N., Saito, K. & Muranaka, T., 2024, In: Plant Biotechnology. 41, 3, p. 289-293 5 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
The phosphorylated pathway of serine biosynthesis affects sperm, embryo, and sporophyte development, and metabolism in Marchantia polymorpha
Wang, M., Tabeta, H., Ohtaka, K., Kuwahara, A., Nishihama, R., Ishikawa, T., Toyooka, K., Sato, M., Wakazaki, M., Akashi, H., Tsugawa, H., Shoji, T., Okazaki, Y., Yoshida, K., Sato, R., Ferjani, A., Kohchi, T. & Hirai, M. Y., 2024/12, In: Communications Biology. 7, 1, 102.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
2023
Anti-Trypanosoma cruzi activity of Coptis rhizome extract and its constituents
Tayama, Y., Mizukami, S., Toume, K., Komatsu, K., Yanagi, T., Nara, T., Tieu, P., Huy, N. T., Hamano, S. & Hirayama, K., 2023/12, In: Tropical Medicine and Health. 51, 1, 12.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Downregulation of a cluster of genes encoding nitrate transporter 1/peptide transporter family proteins in tomato with a mutated JRE4 transcription factor
Shoji, T. & Saito, K., 2023, In: Plant Biotechnology. 40, 1, p. 71-76 6 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Essential oil composition of Curcuma species and drugs from Asia analyzed by headspace solid-phase microextraction coupled with gas chromatography–mass spectrometry
Liu, Q., Komatsu, K., Toume, K., Zhu, S., Tanaka, K., Hayashi, S., Anjiki, N., Kawahara, N., Takano, A., Miyake, K., Nakamura, N., Sukrong, S., Agil, M. & Balachandra, I., 2023/01, In: Natural Medicines. 77, 1, p. 152-172 21 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Induced production of specialized steroids by transcriptional reprogramming in Petunia hybrida
Shoji, T., Sugawara, S., Mori, T., Kobayashi, M., Kusano, M. & Saito, K., 2023/10/01, In: PNAS nexus. 2, 10, pgad326.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Metabolite profiling of Drynariae Rhizoma using 1H NMR and HPLC coupled with multivariate statistical analysis
Dong, Y., Toume, K., Kimijima, S., Zhang, H., Zhu, S., He, Y., Cai, S., Maruyama, T. & Komatsu, K., 2023/09, In: Natural Medicines. 77, 4, p. 839-857 19 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Metabolomics analysis of peony root using NMR spectroscopy and impact of the preprocessing method for NMR data in multivariate analysis
Dong, Y., Toume, K., Zhu, S., Shi, Y., Tamura, T., Yoshimatsu, K. & Komatsu, K., 2023/09, In: Natural Medicines. 77, 4, p. 792-816 25 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
2022
A Jasmonate-Responsive ERF Transcription Factor Regulates Steroidal Glycoalkaloid Biosynthesis Genes in Eggplant
Shoji, T. & Saito, K., 2022/12, In: Plants. 11, 23, 3336.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
A RING membrane-anchor E3 ubiquitin ligase gene is co-expressed with steroidal glycoalkaloid biosynthesis genes in tomato
Shoji, T. & Saito, K., 2022, In: Plant Biotechnology. 39, 4, p. 421-425 5 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Discrimination of Curcuma species from Asia using intron length polymorphism markers in genes encoding diketide-CoA synthase and curcumin synthase
Liu, Q., Zhu, S., Hayashi, S., Iida, O., Takano, A., Miyake, K., Sukrong, S., Agil, M., Balachandran, I., Nakamura, N., Kawahara, N. & Komatsu, K., 2022/01, In: Natural Medicines. 76, 1, p. 69-86 18 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Effects of microbial fermentation on enzyme activity and volatile properties of Massa Medicata Fermentata
Wang, Z., Okutsu, K., Yoshizaki, Y., Futagami, T., Tamaki, H., Maruyama, T., Toume, K., Komatsu, K., Hashimoto, F. & Takamine, K., 2022/04, In: Traditional & Kampo Medicine. 9, 1, p. 10-17 8 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Genetic analysis of Curcuma species from Asia based on intron regions of genes encoding diketide-CoA synthase and curcumin synthase
Liu, Q., Zhu, S., Hayashi, S., Anjiki, N., Takano, A., Kawahara, N. & Komatsu, K., 2022/01, In: Natural Medicines. 76, 1, p. 276-280 5 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Memory enhancement effect of saponins from Eleutherococcus senticosus leaves and blood-brain barrier-permeated saponins profiling using a pseudotargeted monitoring strategy
Huang, Y. H., Ding, W. L., Li, X. T., Cai, M. T., Li, H. L., Yang, Z. Y., Piao, X. H., Zhu, S., Tohda, C., Komatsu, K., Wang, S. M. & Ge, Y. W., 2022/02/17, In: Food and Function. 13, 6, p. 3603-3620 18 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Memory enhancement effect of saponins from Eleutherococcus senticosus leaves and blood-brain barrier-permeated saponins profiling using a pseudotargeted monitoring strategy.
Huang, Y.-H., Ding, W.-L., Li, X.-T., Cai, M.-T., Li, H.-L., Yang, Z.-Y., Piao, X.-H., Zhu, S., Tohda, C., Komatsu, K., Wang, S.-M. & Ge, Y.-W., 2022/03/21, In: Food & function. 13, 6, p. 3603-3620 18 p.Research output: Contribution to journal › Article
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Natural and induced variations in transcriptional regulator genes result in low-nicotine phenotypes in tobacco
Shoji, T., Moriyama, K., Sierro, N., Ouadi, S., Ivanov, N. V., Hashimoto, T. & Saito, K., 2022/09, In: Plant Journal. 111, 6, p. 1768-1779 12 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Phenylpropanoid-conjugated iridoid glucosides from leaves of Morinda morindoides
Hashim, Y., Toume, K., Mizukami, S., Kitami, T., Taniguchi, M., Teklemichael, A. A., Tayama, Y., Huy, N. T., Lami, J. N., Bodi, J. M., Hirayama, K. & Komatsu, K., 2022/01, In: Natural Medicines. 76, 1, p. 281-290 10 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
2021
Allylic Hydroxylation Activity Is a Source of Saponin Chemodiversity in the Genus Glycyrrhiza
Fanani, M. Z., Sawai, S., Seki, H., Ishimori, M., Ohyama, K., Fukushima, E. O., Sudo, H., Saito, K. & Muranaka, T., 2021/02/01, In: Plant and Cell Physiology. 62, 2, p. 262-271 10 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Characterization of metabolites in Saposhnikovia divaricata root from Mongolia
Batsukh, Z., Toume, K., Javzan, B., Kazuma, K., Cai, S. Q., Hayashi, S., Atsumi, T., Yoshitomi, T., Uchiyama, N., Maruyama, T., Kawahara, N. & Komatsu, K., 2021/01, In: Natural Medicines. 75, 1, p. 11-27 17 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
CRISPR/Cas9-mediated disruption of the PYRROLIDINE KETIDE SYNTHASE gene reduces the accumulation of tropane alkaloids in Atropa belladonna hairy roots
Hasebe, F., Yuba, H., Hashimoto, T., Saito, K., Funa, N. & Shoji, T., 2021/12/01, In: Bioscience, biotechnology, and biochemistry. 85, 12, p. 2404-2409 6 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
Current status of pharmaceutical education for self-medication and quality assurance: Based on evaluation from the questionnaire
Komatsu, K., 2021/06/01, In: Yakugaku Zasshi. 141, 6, p. 793-805 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Genetic diversity of Amomum xanthioides and its related species from Southeast Asia and China
Sone, M., Zhu, S., Cheng, X., Ketphanh, S., Swe, S., Tun, T. L., Kawano, N., Kawahara, N. & Komatsu, K., 2021/09, In: Natural Medicines. 75, 4, p. 798-812 15 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Genetic identification of medicinally used Salacia species by nrDNA ITS sequences and a PCR-RFLP assay for authentication of Salacia-related health foods
Zhu, S., Liu, Q., He, J., Nakajima, N., Samarakoon, S. P., Swe, S., Zaw, K. & Komatsu, K., 2021/06/28, In: Journal of Ethnopharmacology. 274, 113909.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Iridoids isolated from Viticis Fructus inhibit paclitaxel-induced mechanical allodynia in mice
Yu, H., Toume, K., Kurokawa, Y., Andoh, T. & Komatsu, K., 2021/01, In: Natural Medicines. 75, 1, p. 48-55 8 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Phenylpropanoid conjugated iridoids with anti-malarial activity from the leaves of Morinda morindoides
Hashim, Y., Toume, K., Mizukami, S., Ge, Y. W., Taniguchi, M., Teklemichael, A. A., Huy, N. T., Bodi, J. M., Hirayama, K. & Komatsu, K., 2021/09, In: Natural Medicines. 75, 4, p. 915-925 11 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Tomato roots secrete tomatine to modulate the bacterial assemblage of the rhizosphere
Nakayasu, M., Ohno, K., Takamatsu, K., Aoki, Y., Yamazaki, S., Takase, H., Shoji, T., Yazaki, K. & Sugiyama, A., 2021/05, In: Plant Physiology. 186, 1, p. 270-284 15 p.Research output: Contribution to journal › Article › peer-review
Open Access45 Scopus citations -
2020
1H NMR-based metabolomic analysis coupled with reversed-phase solid-phase extraction for sample preparation of Saposhnikovia roots and related crude drugs
Yoshitomi, T., Wakana, D., Uchiyama, N., Tsujimoto, T., Kawano, N., Yokokura, T., Yamamoto, Y., Fuchino, H., Hakamatsuka, T., Komatsu, K., Kawahara, N. & Maruyama, T., 2020/01/01, In: Natural Medicines. 74, 1, p. 65-75 11 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
Anti-malarial activity of traditional Kampo medicine Coptis rhizome extract and its major active compounds
Teklemichael, A. A., Teklemichael, A. A., Teklemichael, A. A., Mizukami, S., Mizukami, S., Toume, K., Mosaddeque, F., Mosaddeque, F., Kamel, M. G., Kaneko, O., Kaneko, O., Kaneko, O., Komatsu, K., Karbwang, J., Karbwang, J., Huy, N. T. & Hirayama, K., 2020/06/08, In: Malaria Journal. 19, 1, 204.Research output: Contribution to journal › Article › peer-review
Open Access -
Deglycosylation of the isoflavone C-glucoside puerarin by a combination of two recombinant bacterial enzymes and 3-oxo-glucose
Nakamura, K., Zhu, S., Komatsu, K., Hattori, M. & Iwashima, M., 2020/07/01, In: Applied and Environmental Microbiology. 86, 14, e00607.Research output: Contribution to journal › Article › peer-review
Open Access30 Scopus citations -
Discovery of prenylated dihydrostilbenes in Glycyrrhiza uralensis leaves by UHPLC-MS using neutral loss scan
Meng, H. C., Zhu, S., Fan, Y. H., Ye, R., Hattori, M., Komatsu, K. & Ma, C. M., 2020/09/15, In: Industrial Crops and Products. 152, 112557.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Genetic Manipulation of Transcriptional Regulators Alters Nicotine Biosynthesis in Tobacco
Hayashi, S., Watanabe, M., Kobayashi, M., Tohge, T., Hashimoto, T. & Shoji, T., 2020/04/08, In: Plant and Cell Physiology. 61, 6, p. 1041-1053 13 p.Research output: Contribution to journal › Article › peer-review
Open Access39 Scopus citations -
Identifying the compounds that can distinguish between Saposhnikovia root and its substitute, Peucedanum ledebourielloides root, using LC-HR/MS metabolomics
Yoshitomi, T., Wakana, D., Uchiyama, N., Tsujimoto, T., Kawano, N., Yokokura, T., Yamamoto, Y., Fuchino, H., Hakamatsuka, T., Komatsu, K., Kawahara, N. & Maruyama, T., 2020/06/01, In: Natural Medicines. 74, 3, p. 550-560 11 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Metabolomic profiling of Saposhnikoviae Radix from Mongolia by LC–IT–TOF–MS/MS and multivariate statistical analysis
Batsukh, Z., Toume, K., Javzan, B., Kazuma, K., Cai, S. Q., Hayashi, S., Kawahara, N., Maruyama, T. & Komatsu, K., 2020/01/01, In: Natural Medicines. 74, 1, p. 170-188 19 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Microbial Community Structure and Chemical Constituents in Shinkiku, a Fermented Crude Drug Used in Kampo Medicine
Wang, Z., Okutsu, K., Futagami, T., Yoshizaki, Y., Tamaki, H., Maruyama, T., Toume, K., Komatsu, K., Hashimoto, F. & Takamine, K., 2020/07/31, In: Frontiers in Nutrition. 7, 115.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Targeted genome editing in tetraploid potato through transient talen expression by agrobacterium infection
Yasumoto, S., Sawai, S., Lee, H. J., Mizutani, M., Saito, K., Umemoto, N. & Muranaka, T., 2020/06, In: Plant Biotechnology. 37, 2, p. 205-211 7 p.Research output: Contribution to journal › Article › peer-review
Open Access24 Scopus citations -
2019
Efficient genome engineering using platinum talein potato
Yasumoto, S., Umemoto, N., Lee, H. J., Nakayasu, M., Sawai, S., Sakuma, T., Yamamoto, T., Mizutani, M., Saito, K. & Muranaka, T., 2019, In: Plant Biotechnology. 36, 3, p. 167-173 7 p.Research output: Contribution to journal › Article › peer-review
Open Access35 Scopus citations -
Expression and characterization of the human intestinal bacterial enzyme which cleaves the c-glycosidic bond in 3″-oxo-puerarin
Nakamura, K., Zhu, S., Komatsu, K., Hattori, M. & Iwashima, M., 2019, In: Biological and Pharmaceutical Bulletin. 42, 3, p. 417-423 7 p.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
Expression of a tobacco nicotine biosynthesis gene depends on the JRE4 transcription factor in heterogenous tomato
Shoji, T. & Hashimoto, T., 2019/03/01, In: Journal of Plant Research. 132, 2, p. 173-180 8 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
Gastroprotective effect of araloside A on ethanol- and aspirin-induced gastric ulcer in mice: involvement of H + /K + -ATPase and mitochondrial-mediated signaling pathway
He, H., Li, X., Yu, H., Zhu, S., He, Y., Komatsu, K., Guo, D., Li, X., Wang, J., Luo, H., Xu, D. & Zou, K., 2019/03/15, In: Natural Medicines. 73, 2, p. 339-352 14 p.Research output: Contribution to journal › Article › peer-review
51 Scopus citations -
Genetic polymorphism of Japanese cultivated Rheum species in the internal transcribed spacer region of nuclear ribosomal DNA
Asanuma, M., Zhu, S., Okura, N., Cai, S. Q., Yoshimatsu, K. & Komatsu, K., 2019/06/14, In: Natural Medicines. 73, 3, p. 541-554 14 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
Identification of genes regulated by a jasmonate-and salt-inducible transcription factor JRE3 in tomato
Abdelkareem, A., Thagun, C., Imanishi, S., Hashimoto, T. & Shoji, T., 2019, In: Plant Biotechnology. 36, 1, p. 29-37 9 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Memory enhancement by oral administration of extract of Eleutherococcus senticosus leaves and active compounds transferred in the brain
Yamauchi, Y., Ge, Y. W., Yoshimatsu, K., Komastu, K., Kuboyama, T., Yang, X. & Tohda, C., 2019/05, In: Nutrients. 11, 5, 1142.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
Molecular Basis of C-30 Product Regioselectivity of Legume Oxidases Involved in High-Value Triterpenoid Biosynthesis
Fanani, M. Z., Fukushima, E. O., Sawai, S., Tang, J., Ishimori, M., Sudo, H., Ohyama, K., Seki, H., Saito, K. & Muranaka, T., 2019/11/26, In: Frontiers in Plant Science. 10, 1520.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
Monoglycerol ester, galloylglucoside and phenolic derivatives from Gymnosporia senegalensis leaves
Tatsimo, J. S. N., Toume, K., Nagata, T., Havyarimana, L., Fujii, T. & Komatsu, K., 2019/04, In: Biochemical Systematics and Ecology. 83, p. 33-38 6 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Screening inducers of neuronal BDNF gene transcription using primary cortical cell cultures from BDNF-luciferase transgenic mice
Fukuchi, M., Okuno, Y., Nakayama, H., Nakano, A., Mori, H., Mitazaki, S., Nakano, Y., Toume, K., Jo, M., Takasaki, I., Watanabe, K., Shibahara, N., Komatsu, K., Tabuchi, A. & Tsuda, M., 2019/12/01, In: Scientific Reports. 9, 1, 11833.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
Search of anti-allodynic compounds from Plantaginis Semen, a crude drug ingredient of Kampo formula “Goshajinkigan”
Toume, K., Hou, Z., Yu, H., Kato, M., Maesaka, M., Bai, Y., Hanazawa, S., Ge, Y., Andoh, T. & Komatsu, K., 2019/09/13, In: Natural Medicines. 73, 4, p. 761-768 8 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
2018
Botanical origin and chemical constituents of commercial Saposhnikoviae radix and its related crude drugs available in Shaanxi and the surrounding regions
Maruyama, T., Ezaki, M., Shiba, M., Yamaji, H., Yoshitomi, T., Kawano, N., Zhu, S., Cheng, X., Yokokura, T., Yamamoto, Y., Fuchino, H., Sun, H., Komatsu, K. & Kawahara, N., 2018/01/01, In: Natural Medicines. 72, 1, p. 267-273 7 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Coculture of a Pathogenic Actinomycete and Animal Cells to Produce Nocarjamide, a Cyclic Nonapeptide with Wnt Signal-Activating Effect
Hara, Y., Arai, M. A., Toume, K., Masu, H., Sato, T., Komatsu, K., Yaguchi, T. & Ishibashi, M., 2018/09/21, In: Organic Letters. 20, 18, p. 5831-5834 4 p.Research output: Contribution to journal › Article › peer-review
20 Scopus citations