Internal Medicine （1）

Search results

  • Family history of diabetes in both parents is strongly associated with impaired residual β-cell function in Japanese type 2 diabetes patients

    Iwata, M., Kamura, Y., Honoki, H., Kobayashi, K., Ishiki, M., Yagi, K., Fukushima, Y., Takano, A., Kato, H., Murakami, S., Higuchi, K., Kobashi, C., Fukuda, K., Koshimizu, Y. & Tobe, K., 2020/05/01, In: Journal of Diabetes Investigation. 11, 3, p. 564-572 9 p.

    Research output: Contribution to journal › Article › peer-review

    7 Scopus citations

  • Fate of adipocyte progenitors during adipogenesis in mice fed a high-fat diet

    Bilal, M., Nawaz, A., Kado, T., Aslam, M. R., Igarashi, Y., Nishimura, A., Watanabe, Y., Kuwano, T., Liu, J., Miwa, H., Era, T., Ikuta, K., Imura, J., Yagi, K., Nakagawa, T., Fujisaka, S. & Tobe, K., 2021/12, In: Molecular Metabolism. 54, 101328.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    20 Scopus citations

  • First-Line, Non-Criterial Antiphospholipid Antibody Testing for the Diagnosis of Antiphospholipid Syndrome in Clinical Practice: A Combination of Anti–β2-Glycoprotein I Domain I and Anti–Phosphatidylserine/Prothrombin Complex Antibodies Tests

    Nakamura, H., Oku, K., Amengual, O., Ohmura, K., Fujieda, Y., Kato, M., Bohgaki, T., Yasuda, S. & Atsumi, T., 2018/04, In: Arthritis Care and Research. 70, 4, p. 627-634 8 p.

    Research output: Contribution to journal › Article › peer-review

    43 Scopus citations

  • Four unrelated cases with Takayasu arteritis and CD36 deficiency: Possible link between these disorders [2]

    Yagi, K., Kobayashi, J., Yasue, S., Yamaguchi, M., Shiobara, S. & Mabuchi, H., 2004/06, In: Journal of Internal Medicine. 255, 6, p. 688-689 2 p.

    Research output: Contribution to journal › Letter › peer-review

    Open Access
    5 Scopus citations

  • Fragmented QRS on electrocardiography as a predictor for diastolic cardiac dysfunction in type 2 diabetes

    Yagi, K., Imamura, T., Tada, H., Liu, J., Miyamoto, Y., Ohbatake, A., Ito, N., Shikata, M., Enkaku, A., Takikawa, A., Honoki, H., Fujisaka, S., Chujo, D., Origasa, H., Kinugawa, K. & Tobe, K., 2022/06, In: Journal of Diabetes Investigation. 13, 6, p. 1052-1061 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    2 Scopus citations

  • Fructose induced KHK-C can increase ER stress independent of its effect on lipogenesis to drive liver disease in diet-induced and genetic models of NAFLD

    Park, S. H., Helsley, R. N., Fadhul, T., Willoughby, J. L. S., Noetzli, L., Tu, H. C., Solheim, M. H., Fujisaka, S., Pan, H., Dreyfuss, J. M., Bons, J., Rose, J., King, C. D., Schilling, B., Lusis, A. J., Pan, C., Gupta, M., Kulkarni, R. N., Fitzgerald, K. & Kern, P. A. & 3 others, Divanovic, S., Kahn, C. R. & Softic, S., 2023/08, In: Metabolism. 145, 155591.

    Research output: Contribution to journal › Article › peer-review

    19 Scopus citations

  • FTO gene polymorphism is associated with type 2 diabetes through its effect on increasing the maximum BMI in Japanese men

    Kamura, Y., Iwata, M., Maeda, S., Shinmura, S., Koshimizu, Y., Honoki, H., Fukuda, K., Ishiki, M., Usui, I., Fukushima, Y., Takano, A., Kato, H., Murakami, S., Higuchi, K., Kobashi, C. & Tobe, K., 2016/11, In: PLoS ONE. 11, 11, e0165523.

    Research output: Contribution to journal › Article › peer-review

    28 Scopus citations

  • Generation and characterization of a Meflin- CreERT2transgenic line for lineage tracing in white adipose tissue

    Kuwano, T., Izumi, H., Aslam, M. R., Igarashi, Y., Bilal, M., Nishimura, A., Watanabe, Y., Nawaz, A., Kado, T., Ikuta, K., Yamamoto, S., Sasahara, M., Fujisaka, S., Yagi, K., Mori, H. & Tobe, K., 2021/03, In: PLoS ONE. 16, 3 March, e0248267.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    7 Scopus citations

  • Gene targeting approaches for diabetes research

    Ohsugi, M., Tobe, K., Kubota, T., Kubota, N., Terauchi, Y. & Kadowaki, T., 2005/06, In: Nihon rinsho. Japanese journal of clinical medicine. 63 Suppl 6, p. 111-124 14 p.

    Research output: Contribution to journal › Review article › peer-review

  • Genetic factors and life styles related to diabetes mellitus--with special reference to multiple factor inheritance

    Terauchi, Y., Tobe, K. & Kadowaki, T., 2000/08/10, In: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine. 89, 8, p. 1500-1506 7 p.

    Research output: Contribution to journal › Review article › peer-review

    Open Access

  • Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population

    Kara, K., Boutin, P., Mori, Y., Tobe, K., Dina, C., Yasuda, K., Yamauchi, T., Otabe, S., Okada, T., Eto, K., Kadowaki, H., Hagura, R., Akanuma, Y., Yazaki, Y., Nagai, R., Taniyama, M., Matsubara, K., Yoda, M., Nakano, Y. & Kimura, S. & 5 others, Tomita, M., Kimura, S., Ito, C., Froguel, P. & Kadowaki, T., 2002, In: Diabetes. 51, 2, p. 536-540 5 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    657 Scopus citations

  • Genome-wide search for type 2 diabetes in Japanese affected sib-pairs confirms susceptibility genes on 3q, 15q, and 20q and identifies two new candidate loci on 7p and 1 lp

    Mori, Y., Otabe, S., Dina, C., Yasuda, K., Populaire, C., Lecoeur, C., Vatin, V., Durand, E., Hara, K., Okada, T., Tobe, K., Boutin, P., Kadowaki, T. & Froguel, P., 2002, In: Diabetes. 51, 4, p. 1247-1255 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    234 Scopus citations

  • Glimepiride-induced bronchial asthma

    Tsukamoto, K., Suzuki, K. O. R., Hara, M., Osuga, J. I., Tobe, K. & Kadowaki, T., 2008/12, In: Diabetes Care. 31, 12, p. e91

    Research output: Contribution to journal › Letter › peer-review

    Open Access
    3 Scopus citations

  • Glucocorticoid tapering pace in microscopic polyangiitis and granulomatosis with polyangiitis in Japanese real-world practice: A propensity score-matched retrospective cohort study from the J-CANVAS registry

    Nishioka, R., Omura, S., Nakagomi, D., Abe, Y., Kadoya, M., Takizawa, N., Nomura, A., Kukida, Y., Kondo, N., Yamano, Y., Yanagida, T., Endo, K., Hirata, S., Matsui, K., Takeuchi, T., Ichinose, K., Kato, M., Yanai, R., Matsuo, Y. & Shimojima, Y. & 12 others, Okazaki, R., Takata, T., Ito, T., Moriyama, M., Takatani, A., Miyawaki, Y., Ito-Ihara, T., Kawaguchi, T., Yajima, N., Kida, T., Kawahito, Y. & Mizushima, I., 2025/05/01, In: Modern Rheumatology. 35, 3, p. 496-504 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Glycogen synthase kinase 3β/CCR6-positive bone marrow cells correlate with disease activity in multicentric Castleman disease-TAFRO

    Abe, N., Kono, M., Kono, M., Ohnishi, N., Sato, T., Tarumi, M., Yoshimura, M., Sato, T., Karino, K., Shimizu, Y., Fujieda, Y., Kato, M., Hasebe, R., Oku, K., Murakami, M. & Atsumi, T., 2022/03, In: British Journal of Haematology. 196, 5, p. 1194-1204 11 p.

    Research output: Contribution to journal › Article › peer-review

    4 Scopus citations

  • Growth hormone and prolactin stimulate tyrosine phosphorylation of insulin receptor substrate-1, -2, and -3, their association with p85 phosphatidylinositol 3-kinase (PI3-kinase), and concomitantly PI3-kinase activation via JAK2 kinase

    Yamauchi, T., Yasushi, K., Ueki, K., Tsuji, Y., Stark, G. R., Kerr, I. M., Tsushima, T., Akanuma, Y., Komuro, I., Tobe, K., Yazaki, Y. & Kadowaki, T., 1998/06/19, In: Journal of Biological Chemistry. 273, 25, p. 15719-15726 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    152 Scopus citations

  • Growth hormone-induced tyrosine phosphorylation of EGF receptor as an essential element leading to MAP kinase activation and gene expression

    Yamauchi, T., Ueki, K., Tobe, K., Tamemoto, H., Sekine, N., Wada, M., Honjo, M., Takahashi, M., Takahashi, T., Hirai, H., Tsushima, T., Akanuma, Y., Fujita, T., Komuro, I., Yazaki, Y. & Kadowaki, T., 1998/04, In: Endocrine Journal. 45, SUPPL., p. S27-S31

    Research output: Contribution to journal › Article › peer-review

    Open Access
    50 Scopus citations

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

    Klionsky, D. J., Abdel-Aziz, A. K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., Abeliovich, H., Abildgaard, M. H., Abudu, Y. P., Acevedo-Arozena, A., Adamopoulos, I. E., Adeli, K., Adolph, T. E., Adornetto, A., Aflaki, E., Agam, G., Agarwal, A., Aggarwal, B. B., Agnello, M. & Agostinis, P. & 2,909 others, Agrewala, J. N., Agrotis, A., Aguilar, P. V., Ahmad, S. T., Ahmed, Z. M., Ahumada-Castro, U., Aits, S., Aizawa, S., Akkoc, Y., Akoumianaki, T., Akpinar, H. A., Al-Abd, A. M., Al-Akra, L., Al-Gharaibeh, A., Alaoui-Jamali, M. A., Alberti, S., Alcocer-Gómez, E., Alessandri, C., Ali, M., Alim Al-Bari, M. A., Aliwaini, S., Alizadeh, J., Almacellas, E., Almasan, A., Alonso, A., Alonso, G. D., Altan-Bonnet, N., Altieri, D. C., Álvarez, É. M. C., Alves, S., Alves da Costa, C., Alzaharna, M. M., Amadio, M., Amantini, C., Amaral, C., Ambrosio, S., Amer, A. O., Ammanathan, V., An, Z., Andersen, S. U., Andrabi, S. A., Andrade-Silva, M., Andres, A. M., Angelini, S., Ann, D., Anozie, U. C., Ansari, M. Y., Antas, P., Antebi, A., Antón, Z., Anwar, T., Apetoh, L., Apostolova, N., Araki, T., Araki, Y., Arasaki, K., Araújo, W. L., Araya, J., Arden, C., Arévalo, M. A., Arguelles, S., Arias, E., Arikkath, J., Arimoto, H., Ariosa, A. R., Armstrong-James, D., Arnauné-Pelloquin, L., Aroca, A., Arroyo, D. S., Arsov, I., Artero, R., Asaro, D. M. L., Aschner, M., Ashrafizadeh, M., Ashur-Fabian, O., Atanasov, A. G., Au, A. K., Auberger, P., Auner, H. W., Aurelian, L., Autelli, R., Avagliano, L., Ávalos, Y., Aveic, S., Aveleira, C. A., Avin-Wittenberg, T., Aydin, Y., Ayton, S., Ayyadevara, S., Azzopardi, M., Baba, M., Backer, J. M., Backues, S. K., Bae, D. H., Bae, O. N., Bae, S. H., Baehrecke, E. H., Baek, A., Baek, S. H., Baek, S. H., Bagetta, G., Bagniewska-Zadworna, A., Bai, H., Bai, J., Bai, X., Bai, Y., Bairagi, N., Baksi, S., Balbi, T., Baldari, C. T., Balduini, W., Ballabio, A., Ballester, M., Balazadeh, S., Balzan, R., Bandopadhyay, R., Banerjee, S., Banerjee, S., Bánréti, Á., Bao, Y., Baptista, M. S., Baracca, A., Barbati, C., Bargiela, A., Barilà, D., Barlow, P. G., Barmada, S. J., Barreiro, E., Barreto, G. E., Bartek, J., Bartel, B., Bartolome, A., Barve, G. R., Basagoudanavar, S. H., Bassham, D. C., Bast, R. C., Basu, A., Batoko, H., Batten, I., Baulieu, E. E., Baumgarner, B. L., Bayry, J., Beale, R., Beau, I., Beaumatin, F., Bechara, L. R. G., Beck, G. R., Beers, M. F., Begun, J., Behrends, C., Behrens, G. M. N., Bei, R., Bejarano, E., Bel, S., Behl, C., Belaid, A., Belgareh-Touzé, N., Bellarosa, C., Belleudi, F., Belló Pérez, M., Bello-Morales, R., Beltran, J. S. D. O., Beltran, S., Benbrook, D. M., Bendorius, M., Benitez, B. A., Benito-Cuesta, I., Bensalem, J., Berchtold, M. W., Berezowska, S., Bergamaschi, D., Bergami, M., Bergmann, A., Berliocchi, L., Berlioz-Torrent, C., Bernard, A., Berthoux, L., Besirli, C. G., Besteiro, S., Betin, V. M., Beyaert, R., Bezbradica, J. S., Bhaskar, K., Bhatia-Kissova, I., Bhattacharya, R., Bhattacharya, S., Bhattacharyya, S., Bhuiyan, M. S., Bhutia, S. K., Bi, L., Bi, X., Biden, T. J., Bijian, K., Billes, V. A., Binart, N., Bincoletto, C., Birgisdottir, A. B., Bjorkoy, G., Blanco, G., Blas-Garcia, A., Blasiak, J., Blomgran, R., Blomgren, K., Blum, J. S., Boada-Romero, E., Boban, M., Boesze-Battaglia, K., Boeuf, P., Boland, B., Bomont, P., Bonaldo, P., Bonam, S. R., Bonfili, L., Bonifacino, J. S., Boone, B. A., Bootman, M. D., Bordi, M., Borner, C., Bornhauser, B. C., Borthakur, G., Bosch, J., Bose, S., Botana, L. M., Botas, J., Boulanger, C. M., Boulton, M. E., Bourdenx, M., Bourgeois, B., Bourke, N. M., Bousquet, G., Boya, P., Bozhkov, P. V., Bozi, L. H. M., Bozkurt, T. O., Brackney, D. E., Brandts, C. H., Braun, R. J., Braus, G. H., Bravo-Sagua, R., Bravo-San Pedro, J. M., Brest, P., Bringer, M. A., Briones-Herrera, A., Broaddus, V. C., Brodersen, P., Brodsky, J. L., Brody, S. L., Bronson, P. G., Bronstein, J. M., Brown, C. N., Brown, R. E., Brum, P. C., Brumell, J. H., Brunetti-Pierri, N., Bruno, D., Bryson-Richardson, R. J., Bucci, C., Buchrieser, C., Bueno, M., Buitrago-Molina, L. E., Buraschi, S., Buch, S., Buchan, J. R., Buckingham, E. M., Budak, H., Budini, M., Bultynck, G., Burada, F., Burgoyne, J. R., Burón, M. I., Bustos, V., Büttner, S., Butturini, E., Byrd, A., Cabas, I., Cabrera-Benitez, S., Cadwell, K., Cai, J., Cai, L., Cai, Q., Cairó, M., Calbet, J. A., Caldwell, G. A., Caldwell, K. A., Call, J. A., Calvani, R., Calvo, A. C., Calvo-Rubio Barrera, M., Camara, N. O. S., Camonis, J. H., Camougrand, N., Campanella, M., Campbell, E. M., Campbell-Valois, F. X., Campello, S., Campesi, I., Campos, J. C., Camuzard, O., Cancino, J., Candido de Almeida, D., Canesi, L., Caniggia, I., Canonico, B., Cantí, C., Cao, B., Caraglia, M., Caramés, B., Carchman, E. H., Cardenal-Muñoz, E., Cardenas, C., Cardenas, L., Cardoso, S. M., Carew, J. S., Carle, G. F., Carleton, G., Carloni, S., Carmona-Gutierrez, D., Carneiro, L. A., Carnevali, O., Carosi, J. M., Carra, S., Carrier, A., Carrier, L., Carroll, B., Carter, A. B., Carvalho, A. N., Casanova, M., Casas, C., Casas, J., Cassioli, C., Castillo, E. F., Castillo, K., Castillo-Lluva, S., Castoldi, F., Castori, M., Castro, A. F., Castro-Caldas, M., Castro-Hernandez, J., Castro-Obregon, S., Catz, S. D., Cavadas, C., Cavaliere, F., Cavallini, G., Cavinato, M., Cayuela, M. L., Cebollada Rica, P., Cecarini, V., Cecconi, F., Cechowska-Pasko, M., Cenci, S., Ceperuelo-Mallafré, V., Cerqueira, J. J., Cerutti, J. M., Cervia, D., Cetintas, V. B., Cetrullo, S., Chae, H. J., Chagin, A. S., Chai, C. Y., Chakrabarti, G., Chakrabarti, O., Chakraborty, T., Chakraborty, T., Chami, M., Chamilos, G., Chan, D. W., Chan, E. Y. W., Chan, E. D., Chan, H. Y. E., Chan, H. H., Chan, H., Chan, M. T. V., Chan, Y. S., Chandra, P. K., Chang, C. P., Chang, C., Chang, H. C., Chang, K., Chao, J., Chapman, T., Charlet-Berguerand, N., Chatterjee, S., Chaube, S. K., Chaudhary, A., Chauhan, S., Chaum, E., Checler, F., Cheetham, M. E., Chen, C. S., Chen, G. C., Chen, J. F., Chen, L. L., Chen, L., Chen, L., Chen, M., Chen, M. K., Chen, N., Chen, Q., Chen, R. H., Chen, S., Chen, W., Chen, W., Chen, X. M., Chen, X. W., Chen, X., Chen, Y., Chen, Y. G., Chen, Y., Chen, Y., Chen, Y. J., Chen, Y. Q., Chen, Z. S., Chen, Z., Chen, Z. H., Chen, Z. J., Chen, Z., Cheng, H., Cheng, J., Cheng, S. Y., Cheng, W., Cheng, X., Cheng, X. T., Cheng, Y., Cheng, Z., Chen, Z., Cheong, H., Cheong, J. K., Chernyak, B. V., Cherry, S., Cheung, C. F. R., Cheung, C. H. A., Cheung, K. H., Chevet, E., Chi, R. J., Chiang, A. K. S., Chiaradonna, F., Chiarelli, R., Chiariello, M., Chica, N., Chiocca, S., Chiong, M., Chiou, S. H., Chiramel, A. I., Chiurchiù, V., Cho, D. H., Choe, S. K., Choi, A. M. K., Choi, M. E., Choudhury, K. R., Chow, N. S., Chu, C. T., Chua, J. P., Chua, J. J. E., Chung, H., Chung, K. P., Chung, S., Chung, S. H., Chung, Y. L., Cianfanelli, V., Ciechomska, I. A., Cifuentes, M., Cinque, L., Cirak, S., Cirone, M., Clague, M. J., Clarke, R., Clementi, E., Coccia, E. M., Codogno, P., Cohen, E., Cohen, M. M., Colasanti, T., Colasuonno, F., Colbert, R. A., Colell, A., Čolić, M., Coll, N. S., Collins, M. O., Colombo, M. I., Colón-Ramos, D. A., Combaret, L., Comincini, S., Cominetti, M. R., Consiglio, A., Conte, A., Conti, F., Contu, V. R., Cookson, M. R., Coombs, K. M., Coppens, I., Corasaniti, M. T., Corkery, D. P., Cordes, N., Cortese, K., Costa, M. D. C., Costantino, S., Costelli, P., Coto-Montes, A., Crack, P. J., Crespo, J. L., Criollo, A., Crippa, V., Cristofani, R., Csizmadia, T., Cuadrado, A., Cui, B., Cui, J., Cui, Y., Cui, Y., Culetto, E., Cumino, A. C., Cybulsky, A. V., Czaja, M. J., Czuczwar, S. J., D’Adamo, S., D’Amelio, M., D’Arcangelo, D., D’Lugos, A. C., D’Orazi, G., da Silva, J. A., Dafsari, H. S., Dagda, R. K., Dagdas, Y., Daglia, M., Dai, X., Dai, Y., Dai, Y., Dal Col, J., Dalhaimer, P., Dalla Valle, L., Dallenga, T., Dalmasso, G., Damme, M., Dando, I., Dantuma, N. P., Darling, A. L., Das, H., Dasarathy, S., Dasari, S. K., Dash, S., Daumke, O., Dauphinee, A. N., Davies, J. S., Dávila, V. A., Davis, R. J., Davis, T., Dayalan Naidu, S., De Amicis, F., De Bosscher, K., De Felice, F., De Franceschi, L., De Leonibus, C., de Mattos Barbosa, M. G., De Meyer, G. R. Y., De Milito, A., De Nunzio, C., De Palma, C., De Santi, M., De Virgilio, C., De Zio, D., Debnath, J., DeBosch, B. J., Decuypere, J. P., Deehan, M. A., Deflorian, G., DeGregori, J., Dehay, B., Del Rio, G., Delaney, J. R., Delbridge, L. M. D., Delorme-Axford, E., Delpino, M. V., Demarchi, F., Dembitz, V., Demers, N. D., Deng, H., Deng, Z., Dengjel, J., Dent, P., Denton, D., DePamphilis, M. L., Der, C. J., Deretic, V., Descoteaux, A., Devis, L., Devkota, S., Devuyst, O., Dewson, G., Dharmasivam, M., Dhiman, R., di Bernardo, D., Di Cristina, M., Di Domenico, F., Di Fazio, P., Di Fonzo, A., Di Guardo, G., Di Guglielmo, G. M., Di Leo, L., Di Malta, C., Di Nardo, A., Di Rienzo, M., Di Sano, F., Diallinas, G., Diao, J., Diaz-Araya, G., Díaz-Laviada, I., Dickinson, J. M., Diederich, M., Dieudé, M., Dikic, I., Ding, S., Ding, W. X., Dini, L., Dinić, J., Dinic, M., Dinkova-Kostova, A. T., Dionne, M. S., Distler, J. H. W., Diwan, A., Dixon, I. M. C., Djavaheri-Mergny, M., Dobrinski, I., Dobrovinskaya, O., Dobrowolski, R., Dobson, R. C. J., Đokić, J., Dokmeci Emre, S., Donadelli, M., Dong, B., Dong, X., Dong, Z., Dorn, G. W., Dotsch, V., Dou, H., Dou, J., Dowaidar, M., Dridi, S., Drucker, L., Du, A., Du, C., Du, G., Du, H. N., Du, L. L., du Toit, A., Duan, S. B., Duan, X., Duarte, S. P., Dubrovska, A., Dunlop, E. A., Dupont, N., Durán, R. V., Dwarakanath, B. S., Dyshlovoy, S. 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C., Fernández-Veledo, S., Fernie, A. R., Ferrante, A. W., Ferraresi, A., Ferrari, M. F., Ferreira, J. C. B., Ferro-Novick, S., Figueras, A., Filadi, R., Filigheddu, N., Filippi-Chiela, E., Filomeni, G., Fimia, G. M., Fineschi, V., Finetti, F., Finkbeiner, S., Fisher, E. A., Fisher, P. B., Flamigni, F., Fliesler, S. J., Flo, T. H., Florance, I., Florey, O., Florio, T., Fodor, E., Follo, C., Fon, E. A., Forlino, A., Fornai, F., Fortini, P., Fracassi, A., Fraldi, A., Franco, B., Franco, R., Franconi, F., Frankel, L. B., Friedman, S. L., Fröhlich, L. F., Frühbeck, G., Fuentes, J. M., Fujiki, Y., Fujita, N., Fujiwara, Y., Fukuda, M., Fulda, S., Furic, L., Furuya, N., Fusco, C., Gack, M. U., Gaffke, L., Galadari, S., Galasso, A., Galindo, M. F., Gallolu Kankanamalage, S., Galluzzi, L., Galy, V., Gammoh, N., Gan, B., Ganley, I. G., Gao, F., Gao, H., Gao, M., Gao, P., Gao, S. J., Gao, W., Gao, X., Garcera, A., Garcia, M. N., Garcia, V. 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    Research output: Contribution to journal › Article › peer-review

    Open Access
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    Research output: Contribution to journal › Article › peer-review

    Open Access
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    Research output: Contribution to journal › Article › peer-review

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    Research output: Contribution to journal › Article › peer-review

    Open Access
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    Research output: Contribution to journal › Short survey › peer-review

    Open Access
    5 Scopus citations

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    95 Scopus citations

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    Research output: Contribution to journal › Article › peer-review

    Open Access
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    Research output: Contribution to journal › Short survey › peer-review

    Open Access
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    Research output: Contribution to journal › Article › peer-review

    204 Scopus citations

  • Hyperglycemia associated with IL-6 producing renal cell carcinoma

    Tsukamoto, K., Morisawa, Y., Fukayama, M., Tobe, K., Okada, T., Kouno, M., Asano, T., Ishibashi, S., Shibasaki, Y., Kadowaki, T. & Kimura, S., 2003, In: Journal of the Japan Diabetes Society. 46, 1, p. 15-22 8 p.

    Research output: Contribution to journal › Article › peer-review

    1 Scopus citations

  • Hypertrophic pachymeningitis in ANCA-associated vasculitis: a cross-sectional and multi-institutional study in Japan (J-CANVAS)

    Shimojima, Y., Kishida, D., Ichikawa, T., Kida, T., Yajima, N., Omura, S., Nakagomi, D., Abe, Y., Kadoya, M., Takizawa, N., Nomura, A., Kukida, Y., Kondo, N., Yamano, Y., Yanagida, T., Endo, K., Hirata, S., Matsui, K., Takeuchi, T. & Ichinose, K. & 14 others, Kato, M., Yanai, R., Matsuo, Y., Nishioka, R., Okazaki, R., Takata, T., Ito, T., Moriyama, M., Takatani, A., Miyawaki, Y., Ito-Ihara, T., Kawaguchi, T., Kawahito, Y. & Sekijima, Y., 2022/12, In: Arthritis Research and Therapy. 24, 1, 204.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    13 Scopus citations

  • Hypertrophic pachymeningitis in an individual with microscopic polyangiitis

    Tsuda, R., Taki, H., Shinoda, K., Hounoki, H. & Tobe, K., 2013/06, In: Journal of the American Geriatrics Society. 61, 6, p. 1043-1044 2 p.

    Research output: Contribution to journal › Letter › peer-review

    Open Access
    3 Scopus citations

  • Hypoxia and hypoxia/reoxygenation activate p65(PAK) p38mitogen-activated protein kinase (MAPK), and stress-activated protein kinase (SAPK) in cultured rat cardiac myocytes

    Seko, Y., Takahashi, N., Tobe, K., Kadowaki, T. & Yazaki, Y., 1997/10/29, In: Biochemical and Biophysical Research Communications. 239, 3, p. 840-844 5 p.

    Research output: Contribution to journal › Article › peer-review

    117 Scopus citations

  • Hypoxia and hypoxia/reoxygenation activate Raf-1, mitogen-activated protein kinase kinase, mitogen-activated protein kinases, and S6 kinase in cultured rat cardiac myocytes

    Seko, Y., Tobe, K., Ueki, K., Kadowaki, T. & Yazaki, Y., 1996/01, In: Circulation Research. 78, 1, p. 82-90 9 p.

    Research output: Contribution to journal › Article › peer-review

    112 Scopus citations

  • Hypoxia and hypoxia/reoxygenation activate Src family tyrosine kinases and p21(ras) in cultured rat cardiac myocytes

    Seko, Y., Tobe, K., Takahashi, N., Kaburagi, Y., Kadowaki, T. & Yazaki, Y., 1996/09/13, In: Biochemical and Biophysical Research Communications. 226, 2, p. 530-535 6 p.

    Research output: Contribution to journal › Article › peer-review

    54 Scopus citations

  • Hypoxia induces activation and subcellular translocation of focal adhesion kinase (p125(FAK)) in cultured rat cardiac myocytes

    Seko, Y., Takahashi, N., Sabe, H., Tobe, K., Kadowaki, T. & Nagai, R., 1999/08/19, In: Biochemical and Biophysical Research Communications. 262, 1, p. 290-296 7 p.

    Research output: Contribution to journal › Article › peer-review

    36 Scopus citations

  • Identification of a 190-kDa protein as a novel substrate for the insulin receptor kinase functionally similar to insulin receptor substrate-1

    Tobe, K., Tamemoto, H., Yamauchi, T., Aizawa, S., Yazaki, Y. & Kadowaki, T., 1995/03/17, In: Journal of Biological Chemistry. 270, 11, p. 5698-5701 4 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    97 Scopus citations

  • Identification of herbal drug extracts that promote growth of Akkermansia muciniphila in high-fat diet fed mice

    Fujisaka, S., Watanabe, Y., Toume, K., Morinaga, Y., Nawaz, A., Kado, T., Nishimura, A., Bilal, M., Aslam, M. R., Igarashi, Y., Nakagawa, Y. & Tobe, K., 2024/07, In: Diabetology International. 15, 3, p. 495-506 12 p.

    Research output: Contribution to journal › Article › peer-review

    1 Scopus citations

  • IgG4-related periarteritis in the superficial temporal artery, clinically mimicking giant cell arthritis

    Kataoka, K., Takemoto, K., Makino, T., Mizawa, M., Yamaguchi, S., Shinoda, K., Toyomoto, T. & Shimizu, T., 2024/03/01, In: European Journal of Dermatology. 34, 2, p. 198-200 3 p.

    Research output: Contribution to journal › Comment/debate

    1 Scopus citations

  • IL-7Rα signaling in regulatory T cells of adipose tissue is essential for systemic glucose homeostasis

    Tani-Ichi, S., Abe, S., Miyachi, H., Kitano, S., Shimba, A., Ejima, A., Hara, T., Cui, G., Kado, T., Hori, S., Tobe, K. & Ikuta, K., 2025/04/01, In: Journal of Immunology. 214, 4, p. 666-679 14 p.

    Research output: Contribution to journal › Article › peer-review

  • Immune Checkpoint Inhibitor Therapy for Patients With Non-small Cell Lung Cancer Ineligible for Platinum Doublet Chemotherapy

    Inomata, M., Minatoyama, S., Takata, N., Hayashi, K., Hirai, T., Seto, Z., Tokui, K., Taka, C., Okazawa, S., Kambara, K., Imanishi, S., Miwa, T., Matsuyama, K., Hayashi, R., Matsui, S. & Tobe, K., 2024/03, In: Anticancer Research. 44, 3, p. 1241-1245 5 p.

    Research output: Contribution to journal › Article › peer-review

    1 Scopus citations

  • Impact of anti-apoptotic and anti-oxidative effects of bone marrow mesenchymal stem cells with transient overexpression of heme oxygenase-1 on myocardial ischemia

    Tsubokawa, T., Yagi, K., Nakanishi, C., Zuka, M., Nohara, A., Ino, H., Fujino, N., Konno, T., Kawashiri, M. A., Ishibashi-Ueda, H., Nagaya, N. & Yamagishi, M., 2010/05, In: American Journal of Physiology - Heart and Circulatory Physiology. 298, 5, p. H1320-H1329

    Research output: Contribution to journal › Article › peer-review

    100 Scopus citations

  • Impact of divergent effects of astaxanthin on insulin signaling in L6 cells

    Ishiki, M., Nishida, Y., Ishibashi, H., Wada, T., Fujisaka, S., Takikawa, A., Urakaze, M., Sasaoka, T., Usui, I. & Tobe, K., 2013/08/01, In: Endocrinology. 154, 8, p. 2600-2612 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    76 Scopus citations

  • Impact of genetic background and ablation of insulin receptor substrate (IRS)-3 on IRS-2 knock-out mice

    Terauchi, Y., Matsui, J., Suzuki, R., Kubota, N., Komeda, K., Aizawa, S., Eto, K., Kimura, S., Nagai, R., Tobe, K., Lienhard, G. E. & Kadowaki, T., 2003/04/18, In: Journal of Biological Chemistry. 278, 16, p. 14284-14290 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    31 Scopus citations

  • Impact of Vancomycin Treatment and Gut Microbiota on Bile Acid Metabolism and the Development of Non-Alcoholic Steatohepatitis in Mice

    Kasai, K., Igarashi, N., Tada, Y., Kani, K., Takano, S., Yanagibashi, T., Usui-Kawanishi, F., Fujisaka, S., Watanabe, S., Ichimura-Shimizu, M., Takatsu, K., Tobe, K., Tsuneyama, K., Furusawa, Y. & Nagai, Y., 2023/02, In: International Journal of Molecular Sciences. 24, 4, 4050.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    9 Scopus citations

  • Impacts of visceral adipose tissue and subcutaneous adipose tissue on metabolic risk factors in middle-aged japanese

    Oka, R., Miura, K., Sakurai, M., Nakamura, K., Yagi, K., Miyamoto, S., Moriuchi, T., Mabuchi, H., Koizumi, J., Nomura, H., Takeda, Y., Inazu, A., Nohara, A., Kawashiri, M. A., Nagasawa, S., Kobayashi, J. & Yamagishi, M., 2010/01, In: Obesity. 18, 1, p. 153-160 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    74 Scopus citations

  • Inactivation of DNA-Dependent Protein Kinase Promotes Heat-Induced Apoptosis Independently of Heat-Shock Protein Induction in Human Cancer Cell Lines

    Okazawa, S., Furusawa, Y., Kariya, A., Hassan, M. A., Arai, M., Hayashi, R., Tabuchi, Y., Kondo, T. & Tobe, K., 2013/03/11, In: PLoS ONE. 8, 3, e58325.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    12 Scopus citations

  • Incidence and risk of antiresorptive agent-related osteonecrosis of the jaw (ARONJ) after tooth extraction in patients with autoimmune disease

    Fujieda, Y., Doi, M., Asaka, T., Ota, M., Hisada, R., Ohnishi, N., Kono, M., Kameda, H., Nakazawa, D., Kato, M., Amengual, O., Takahata, M., Yasuda, S., Kitagawa, Y. & Atsumi, T., 2020/07/01, In: Journal of Bone and Mineral Metabolism. 38, 4, p. 581-588 8 p.

    Research output: Contribution to journal › Article › peer-review

    11 Scopus citations

  • Increased Expression of the Sterol Regulatory Element-binding Protein-1 Gene in Insulin Receptor Substrate-2-/- Mouse Liver

    Tobe, K., Suzuki, R., Aoyama, M., Yamauchi, T., Kamon, J., Kubota, N., Terauchi, Y., Matsui, J., Akanuma, Y., Kimura, S., Tanaka, J., Abe, M., Ohsumi, J., Nagai, R. & Kadowaki, T., 2001/10/19, In: Journal of Biological Chemistry. 276, 42, p. 38337-38340 4 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    121 Scopus citations

  • Increased insulin sensitivity and hypoglycaemia in mice lacking the p85α subunit of phosphoinositide 3-kinase

    Terauchi, Y., Tsuji, Y., Satoh, S., Minoura, H., Murakami, K., Okuno, A., Inukai, K., Asano, T., Kaburagi, Y., Ueki, K., Nakajima, H., Hanafusa, T., Matsuzawa, Y., Sekihara, H., Yin, Y., Barrett, J. C., Oda, H., Ishikawa, T., Akanuma, Y. & Komuro, I. & 10 others, Suzuki, M., Yamamura, K. I., Kodama, T., Suzuki, H., Koyasu, S., Aizawa, S., Tobe, K., Fukui, Y., Yazaki, Y. & Kadowaki, T., 1999/02, In: Nature Genetics. 21, 2, p. 230-235 6 p.

    Research output: Contribution to journal › Article › peer-review

    360 Scopus citations

  • Increased Number of Mucosal-Associated Invariant T Cells Is Associated with the Inhibition of Nonalcoholic Fatty Liver Disease in High Fat Diet–Fed Mice

    Kishi, H., Usui, I., Jojima, T., Fujisaka, S., Wakamatsu, S., Mizunuma-Inoue, Y., Niitani, T., Sakurai, S., Iijima, T., Tomaru, T., Tobe, K. & Aso, Y., 2022/12, In: International Journal of Molecular Sciences. 23, 23, 15309.

    Research output: Contribution to journal › Article › peer-review

    3 Scopus citations

  • Inhibition of RXR and PPARγ ameliorates diet-induced obesity and type 2 diabetes

    Yamauchi, T., Waki, H., Kamon, J., Murakami, K., Motojima, K., Komeda, K., Miki, H., Kubota, N., Terauchi, Y., Tsuchida, A., Tsuboyama-Kasaoka, N., Yamauchi, N., Ide, T., Hori, W., Kato, S., Fukayama, M., Akanuma, Y., Ezaki, O., Itai, A. & Nagai, R. & 5 others, Kimura, S., Tobe, K., Kagechika, H., Shudo, K. & Kadowaki, T., 2001, In: Journal of Clinical Investigation. 108, 7, p. 1001-1013 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    303 Scopus citations