History and future perspectives of adipose tissue macrophage biology

Tomonobu Kado*, Ayumi Nishimura, Kazuyuki Tobe*

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review

2 Scopus citations

Abstract

Macrophages contribute to adipose tissue homeostasis; however, they are also thought to be responsible for insulin resistance in obesity. Macrophages, which were oversimplified in past methodologies, have become rather difficult to understand comprehensively as recent developments in research methodology have revealed their diversity. This review highlights recent studies on adipose tissue macrophages, identifies controversial issues that need to be resolved and proposes a scenario for further development of adipose tissue macrophage biology.

Original languageEnglish
Article number1373182
JournalFrontiers in Pharmacology
Volume15
DOIs
StatePublished - 2024

Keywords

  • adipose tissue
  • adipose tissue macrophage
  • diabetes
  • macrophage
  • obesity

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)

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