年別の研究成果
年別の研究成果
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2025
Neural Crest-Derived Mesenchymal Cells Support Thymic Reconstitution After Lethal Irradiation
Tetteh, D. N., Isono, K., Hikosaka-Kuniishi, M. & Yamazaki, H., 2025/01, In: European Journal of Immunology. 55, 1, e202451305.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access1 被引用数 (Scopus) -
2024
Generation and characterization of OX40-ligand fusion protein that agonizes OX40 on T-Lymphocytes
Sato, A., Nagai, H., Suzuki, A., Ito, A., Matsuyama, S., Shibui, N., Morita, M., Hikosaka-Kuniishi, M., Ishii, N. & So, T., 2024, In: Frontiers in Immunology. 15, 1473815.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access -
The Role of TNF Receptor-Associated Factor 5 in the Formation of Germinal Centers by B Cells During the Primary Phase of the Immune Response in Mice
Hikosaka-Kuniishi, M., Iwata, C., Ozawa, Y., Ogawara, S., Wakaizumi, T., Itaya, R., Sunakawa, R., Sato, A., Nagai, H., Morita, M. & So, T., 2024/11, In: International Journal of Molecular Sciences. 25, 22, 12331.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access1 被引用数 (Scopus) -
Transmembrane helix 6 of ABCD4 is indispensable for cobalamin transport
Imai, M., Kawaguchi, K., Morita, M., Imanaka, T. & So, T., 2024/03, In: Journal of Inherited Metabolic Disease. 47, 2, p. 366-373 8 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
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2023
Fundamental Characterization of Antibody Fusion-Single-Chain TNF Recombinant Proteins Directed against Costimulatory TNF Receptors Expressed by T-Lymphocytes
Nagai, H., Azuma, M., Sato, A., Shibui, N., Ogawara, S., Tsutsui, Y., Suzuki, A., Wakaizumi, T., Ito, A., Matsuyama, S., Morita, M., Hikosaka Kuniishi, M., Ishii, N. & So, T., 2023/06, In: Cells. 12, 12, 1596.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access1 被引用数 (Scopus) -
2022
Functional Analysis of the Transcriptional Regulator IκB-ζ in Intestinal Homeostasis
Sasaki, T., Nagashima, H., Okuma, A., Yamauchi, T., Yamasaki, K., Aiba, S., So, T., Ishii, N., Owada, Y., MaruYama, T. & Kobayashi, S., 2022/04, In: Digestive Diseases and Sciences. 67, 4, p. 1252-1259 8 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
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The immunological significance of tumor necrosis factor receptor-associated factors (TRAFs).
So, T., 2022/01/01, In: International Immunology. 34, 1, p. 7-20 14 p.研究成果: ジャーナルへの寄稿 › 学術論文
32 被引用数 (Scopus) -
2021
Acyl-CoA thioesterase activity of peroxisomal ABC protein ABCD1 is required for the transport of very long-chain acyl-CoA into peroxisomes
Kawaguchi, K., Mukai, E., Watanabe, S., Yamashita, A., Morita, M., So, T. & Imanaka, T., 2021/12, In: Scientific Reports. 11, 1, 2192.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access15 被引用数 (Scopus) -
Bone marrow transplantation into Abcd1-deficient mice: Distribution of donor derived-cells and biological characterization of the brain of the recipient mice
Morita, M., Kaizawa, T., Yoda, T., Oyama, T., Asakura, R., Matsumoto, S., Nagai, Y., Watanabe, Y., Watanabe, S., Kobayashi, H., Kawaguchi, K., Yamamoto, S., Shimozawa, N., So, T. & Imanaka, T., 2021/05, In: Journal of Inherited Metabolic Disease. 44, 3, p. 718-727 10 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
1 被引用数 (Scopus) -
Generation of an immortalized astrocytic cell line from Abcd1-deficient H-2KbtsA58 mice to facilitate the study of the role of astrocytes in X-linked adrenoleukodystrophy
Morita, M., Toida, A., Horiuchi, Y., Watanabe, S., Sasahara, M., Kawaguchi, K., So, T. & Imanaka, T., 2021/02, In: Heliyon. 7, 2, e06228.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access7 被引用数 (Scopus) -
Novel ACOX1 mutations in two siblings with peroxisomal acyl-CoA oxidase deficiency
Morita, A., Enokizono, T., Ohto, T., Tanaka, M., Watanabe, S., Takada, Y., Iwama, K., Mizuguchi, T., Matsumoto, N., Morita, M., Takashima, S., Shimozawa, N. & Takada, H., 2021/03, In: Brain and Development. 43, 3, p. 475-481 7 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access9 被引用数 (Scopus) -
The lysosomal protein ABCD4 can transport Vitamin B12 across liposomal membranes in vitro
Kitai, K., Kawaguchi, K., Tomohiro, T., Morita, M., So, T. & Imanaka, T., 2021/01/01, In: Journal of Biological Chemistry. 296, 100654.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access18 被引用数 (Scopus) -
2020
GITR controls intestinal inflammation by suppressing IL-15-dependent NK cell activity
Sakurai, T., Okuyama, Y., Kobayashi, S., Phung, H. T., Asao, A., Kawabe, T., Ndhlovu, L. C., Riccardi, C., Kudo, H., Wada, M., Nio, M., So, T. & Ishii, N., 2020/11/01, In: FASEB Journal. 34, 11, p. 14820-14831 12 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access8 被引用数 (Scopus) -
IQGAP1 restrains T-cell cosignaling mediated by OX40
Okuyama, Y., Nagashima, H., Ushio-Fukai, M., Croft, M., Ishii, N. & So, T., 2020/01/01, In: FASEB Journal. 34, 1, p. 540-554 15 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access12 被引用数 (Scopus) -
TRAF5 Deficiency Ameliorates the Severity of Dextran Sulfate Sodium Colitis by Decreasing TRAF2 Expression in Nonhematopoietic Cells.
Phung, H. T., Nagashima, H., Kobayashi, S., Asano, N., Machiyama, T., Sakurai, T., Tayama, S.-I., Asao, A., Imatani, A., Kawabe, T., Okuyama, Y., Ishii, N. & So, T., 2020/03/10, In: ImmunoHorizons. 4, 3, p. 129-139 11 p.研究成果: ジャーナルへの寄稿 › 学術論文
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TRAF5 promotes plasmacytoid dendritic cell development from bone marrow progenitors
Kobayashi, S., Shiota, Y., Kawabe, T., Phung, H. T., Maruyama, T., Owada, Y., So, T. & Ishii, N., 2020/01/08, In: Biochemical and Biophysical Research Communications. 521, 2, p. 353-359 7 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
3 被引用数 (Scopus) -
2019
TNF receptor-associated factor 5 limits function of plasmacytoid dendritic cells by controlling IFN regulatory factor 5 expression
Kobayashi, S., Sakurai, T., So, T., Shiota, Y., Asao, A., Phung, H. T., Tanaka, R., Kawabe, T., Maruyama, T., Kanno, E., Kawakami, K., Owada, Y. & Ishii, N., 2019/09/15, In: Journal of Immunology. 203, 6, p. 1447-1456 10 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access8 被引用数 (Scopus) -
2018
Characterization of human ATP-binding cassette protein subfamily D reconstituted into proteoliposomes
Okamoto, T., Kawaguchi, K., Watanabe, S., Agustina, R., Ikejima, T., Ikeda, K., Nakano, M., Morita, M. & Imanaka, T., 2018/02/19, In: Biochemical and Biophysical Research Communications. 496, 4, p. 1122-1127 6 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
24 被引用数 (Scopus) -
GITR cosignal in ILC2s controls allergic lung inflammation
Nagashima, H., Okuyama, Y., Fujita, T., Takeda, T., Motomura, Y., Moro, K., Hidaka, T., Omori, K., Sakurai, T., Machiyama, T., Ndhlovu, L. C., Riccardi, C., So, T. & Ishii, N., 2018/05, In: Journal of Allergy and Clinical Immunology. 141, 5, p. 1939-1943.e8研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access48 被引用数 (Scopus) -
Profiling and Imaging of Phospholipids in Brains of Abcd1-Deficient Mice
Hama, K., Fujiwara, Y., Morita, M., Yamazaki, F., Nakashima, Y., Takei, S., Takashima, S., Setou, M., Shimozawa, N., Imanaka, T. & Yokoyama, K., 2018/01, In: Lipids. 53, 1, p. 85-102 18 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access17 被引用数 (Scopus) -
TNF receptor associated factor 5 controls oncostatin M-mediated lung inflammation
Machiyama, T., So, T., Okuyama, Y., Kobayashi, S., Phung, H. T., Asao, A., Harigae, H. & Ishii, N., 2018/05/15, In: Biochemical and Biophysical Research Communications. 499, 3, p. 544-550 7 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
5 被引用数 (Scopus) -
TRAF2 and TRAF5 associated with the signal transducing receptor gp130 limit IL-6-driven transphosphorylation of JAK1 through the inhibition of proximal JAK-JAK interaction
Kimura, M., Nagashima, H., Okuyama, Y., Ishii, N. & So, T., 2018/06/26, In: International Immunology. 30, 7, p. 291-299 9 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access9 被引用数 (Scopus) -
2016
A novel method for determining peroxisomal fatty acid β-oxidation
Morita, M., Matsumoto, S., Okazaki, A., Tomita, K., Watanabe, S., Kawaguchi, K., Minato, D., Matsuya, Y., Shimozawa, N. & Imanaka, T., 2016/09/01, In: Journal of Inherited Metabolic Disease. 39, 5, p. 725-731 7 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
3 被引用数 (Scopus) -
Characterization of the interaction between Trypanosoma brucei Pex5p and its receptor Pex14p
Watanabe, Y., Kawaguchi, K., Okuyama, N., Sugawara, Y., Obita, T., Mizuguchi, M., Morita, M. & Imanaka, T., 2016/01/01, In: FEBS Letters. 590, 2, p. 242-250 9 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access7 被引用数 (Scopus) -
Mesenteric lymph nodes contribute to proinflammatory Th17-cell generation during inflammation of the small intestine in mice
Kawabe, T., Suzuki, N., Yamaki, S., Sun, S. L., Asao, A., Okuyama, Y., So, T., Iwakura, Y. & Ishii, N., 2016/05/01, In: European Journal of Immunology. 46, 5, p. 1119-1131 13 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access17 被引用数 (Scopus) -
Relationship between the magnitude of IgE production in mice and conformational stability of the house dust mite allergen, Der p 2
Nakamura, H., Ohkuri, T., So, T. & Ueda, T., 2016/10/01, In: BBA - General Subjects. 1860, 10, p. 2279-2284 6 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
7 被引用数 (Scopus) -
TNFR-associated factors 2 and 5 differentially regulate the instructive IL-6 receptor signaling required for Th17 development
Nagashima, H., Okuyama, Y., Hayashi, T., Ishii, N. & So, T., 2016/05/15, In: Journal of Immunology. 196, 10, p. 4082-4089 8 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
26 被引用数 (Scopus) -
Translocation of the ABC transporter ABCD4 from the endoplasmic reticulum to lysosomes requires the escort protein LMBD1
Kawaguchi, K., Okamoto, T., Morita, M. & Imanaka, T., 2016/07/26, In: Scientific Reports. 6, 30183.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access44 被引用数 (Scopus) -
2015
Brain microsomal fatty acid elongation is increased in abcd1-deficient mouse during active myelination phase
Morita, M., Kawamichi, M., Shimura, Y., Kawaguchi, K., Watanabe, S. & Imanaka, T., 2015/12/01, In: Metabolic Brain Disease. 30, 6, p. 1359-1367 9 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
6 被引用数 (Scopus) -
2014
Expression of a codon-optimized Aspergillus niger pectin methylesterase gene in the methylotrophic yeast Candida boidinii
Kawaguchi, K., Yurimoto, H. & Sakai, Y., 2014, In: Bioscience, biotechnology, and biochemistry. 78, 4, p. 718-721 4 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access5 被引用数 (Scopus) -
OX40 and IL-7 play synergistic roles in the homeostatic proliferation of effector memory CD4+ T cells
Yamaki, S., Ine, S., Kawabe, T., Okuyama, Y., Suzuki, N., Soroosh, P., Mousavi, S. F., Nagashima, H., Sun, S. L., So, T., Sasaki, T., Harigae, H., Sugamura, K., Kudo, H., Wada, M., Nio, M. & Ishii, N., 2014/10/01, In: European Journal of Immunology. 44, 10, p. 3015-3025 11 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
27 被引用数 (Scopus) -
Role of NH2-terminal hydrophobic motif in the subcellular localization of ATP-binding cassette protein subfamily D: Common features in eukaryotic organisms
Lee, A., Asahina, K., Okamoto, T., Kawaguchi, K., Kostsin, D. G., Kashiwayama, Y., Takanashi, K., Yazaki, K., Imanaka, T. & Morita, M., 2014/10/24, In: Biochemical and Biophysical Research Communications. 453, 3, p. 612-618 7 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
11 被引用数 (Scopus) -
The adaptor TRAF5 limits the differentiation of inflammatory CD4 + T cells by antagonizing signaling via the receptor for IL-6
Nagashima, H., Okuyama, Y., Asao, A., Kawabe, T., Yamaki, S., Nakano, H., Croft, M., Ishii, N. & So, T., 2014/05, In: Nature Immunology. 15, 5, p. 449-456 8 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access40 被引用数 (Scopus) -
2013
Homeostatic proliferation of naive CD4+ T cells in mesenteric lymph nodes generates gut-tropic Th17 cells
Kawabe, T., Sun, S. L., Fujita, T., Yamaki, S., Asao, A., Takahashi, T., So, T. & Ishii, N., 2013/06/01, In: Journal of Immunology. 190, 11, p. 5788-5798 11 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access44 被引用数 (Scopus) -
Molecular species of phospholipids with very long chain fatty acids in skin fibroblasts of Zellweger syndrome
Hama, K., Nagai, T., Nishizawa, C., Ikeda, K., Morita, M., Satoh, N., Nakanishi, H., Imanaka, T., Shimozawa, N., Taguchi, R., Inoue, K. & Yokoyama, K., 2013/12, In: Lipids. 48, 12, p. 1253-1267 15 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
18 被引用数 (Scopus) -
2012
Very long chain fatty acid β-oxidation in astrocytes: Contribution of the ABCD1-dependent and -independent pathways
Morita, M., Shinbo, S., Asahi, A. & Imanaka, T., 2012/11, In: Biological and Pharmaceutical Bulletin. 35, 11, p. 1972-1979 8 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access19 被引用数 (Scopus) -
X-Linked Adrenoleukodystrophy: Molecular and Functional Analysis of the ABCD1 Gene in Argentinean Patients
Amorosi, C. A., Myskóva, H., Monti, M. R., Argaraña, C. E., Morita, M., Kemp, S., de Kremer, R. D., Dvoráková, L. & de Ramírez, A. M. O., 2012/12/31, In: PLoS ONE. 7, 12, e52635.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access13 被引用数 (Scopus) -
2011
ABC subfamily d proteins and very long chain fatty acid metabolism as novel targets in adrenoleukodystrophy
Morita, M., Shimozawa, N., Kashiwayama, Y., Suzuki, Y. & Imanaka, T., 2011, In: Current Drug Targets. 12, 5, p. 694-706 13 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
27 被引用数 (Scopus) -
Antigen-independent signalosome of CARMA1, PKCθ, and TNF receptor-associated factor 2 (TRAF2) determines NF-κB signaling in T cells
So, T., Soroosh, P., Eun, S. Y., Altman, A. & Croft, M., 2011/02/15, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 7, p. 2903-2908 6 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access52 被引用数 (Scopus) -
Herpesvirus entry mediator (TNFRSF14) regulates the persistence of T helper memory cell populations
Soroosh, P., Doherty, T. A., So, T., Mehta, A. K., Khorram, N., Norris, P. S., Scheu, S., Pfeffer, K., Ware, C. & Croft, M., 2011/04/11, In: Journal of Experimental Medicine. 208, 4, p. 797-809 13 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access64 被引用数 (Scopus) -
The structure of physarum polycephalum hemagglutinin i suggests a minimal carbohydrate recognition domain of legume lectin fold
Kouno, T., Watanabe, N., Sakai, N., Nakamura, T., Nabeshima, Y., Morita, M., Mizuguchi, M., Aizawa, T., Demura, M., Imanaka, T., Tanaka, I. & Kawano, K., 2011/01/14, In: Journal of Molecular Biology. 405, 2, p. 560-569 10 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access2 被引用数 (Scopus) -
Yeast methylotrophy and autophagy in a methanol-oscillating environment on growing Arabidopsis thaliana leaves
Kawaguchi, K., Yurimoto, H., Oku, M. & Sakai, Y., 2011/09/26, In: PLoS ONE. 6, 9, e25257.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access57 被引用数 (Scopus) -
2008
Activation of NF-κB1 by OX40 contributes to antigen-driven T cell expansion and survival
Song, J., So, T. & Croft, M., 2008, In: Journal of Immunology. 180, 11, p. 7240-7248 9 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access115 被引用数 (Scopus) -
Immune regulation and control of regulatory T cells by OX40 and 4-1BB
So, T., Lee, S. W. & Croft, M., 2008/06, In: Cytokine and Growth Factor Reviews. 19, 3-4, p. 253-262 10 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access126 被引用数 (Scopus) -
2007
Adrenoleukodystrophy: Subcellular localization and degradation of adrenoleukodystrophy protein (ALDP/ABCD1) with naturally occurring missense mutations
Takahashi, N., Morita, M., Maeda, T., Harayama, Y., Shimozawa, N., Suzuki, Y., Furuya, H., Sato, R., Kashiwayama, Y. & Imanaka, T., 2007/06, In: Journal of Neurochemistry. 101, 6, p. 1632-1643 12 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
28 被引用数 (Scopus) -
Efflux of baicalin, a flavone glucuronide of Scutellariae Radix, on Caco-2 cells through multidrug resistance-associated protein 2
Akao, T., Hanada, M., Sakashita, Y., Sato, K., Morita, M. & Imanaka, T., 2007/01, In: Journal of Pharmacy and Pharmacology. 59, 1, p. 87-93 7 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access49 被引用数 (Scopus) -
Evaluation of the role of the endoplasmic reticulum-golgi transit in the biogenesis of peroxisomal membrane proteins in wild type and peroxisome biogenesis mutant CHO cells
Toro, A., Arredondo, C., Córdova, G., Araya, C., Palacios, J. L., Venegas, A., Morita, M., Imanaka, T. & Santos, M. J., 2007, In: Biological Research. 40, 2, p. 231-249 19 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access6 被引用数 (Scopus) -
Hydrophobic regions adjacent to transmembrane domains 1 and 5 are important for the targeting of the 70-kDa peroxisomal membrane protein
Kashiwayama, Y., Asahina, K., Morita, M. & Imanaka, T., 2007/11/16, In: Journal of Biological Chemistry. 282, 46, p. 33831-33844 14 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access20 被引用数 (Scopus) -
2006
Purification and characterization of benzoate-CoA ligase from Magnetospirillum sp. strain TS-6 capable of aerobic and anaerobic degradation of aromatic compounds
Kawaguchi, K., Shinoda, Y., Yurimoto, H., Sakai, Y. & Kato, N., 2006/04, In: FEMS Microbiology Letters. 257, 2, p. 208-213 6 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
22 被引用数 (Scopus) -
2005
Baicalein 5,6,7-trimethyl ether, a flavonoid derivative, stimulates fatty acid β-oxidation in skin fibroblasts of X-linked adrenoleukodystrophy
Morita, M., Takahashi, I., Kanai, M., Okafuji, F., Iwashima, M., Hayashi, T., Watanabe, S., Hamazaki, T., Shimozawa, N., Suzuki, Y., Furuya, H., Yamada, T. & Imanaka, T., 2005/01/17, In: FEBS Letters. 579, 2, p. 409-414 6 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
22 被引用数 (Scopus)