Projects per year
Personal profile
Campus career
ヒューマン・生命情報システム学系 教授 2006/04/01-2019/09/30
工学科 教授 2018/04/01-2019/09/30
工学科 教授 2019/10/01-2022/03/31
工学系 教授 2019/10/01-2022/03/31
工学科 特別研究教授 2022/04/01-
工学系 特別研究教授 2022/04/01-
Research Fields, Keywords
- Molecular Genetics
Field of expertise (Grants-in-aid for Scientific Research classification)
- Human genetics
- Molecular Oncology
- Genome Medical Science
- General medical chemistry
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Collaborations and top research areas from the last five years
Projects
- 4 Finished
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Elucidation of ligands of cancer-specific monomorphic major histocompatibility complexes and development of novel antibody therapies
Isobe, M. (PI)
2021/04/01 → 2024/03/31
Project: Research
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Development of the system for isolation of T-cell receptor like antibodies against tumor stem cells
Isobe, M. (PI)
2015/04/01 → 2017/03/31
Project: Research
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Development of methods for isolation of human monoclonal antibodies recognizing cancer stem cells
Isobe, M. (PI)
2013/04/01 → 2015/03/31
Project: Research
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Development and analysis of human monoclonal antibodies derived from patients with cancer
Isobe, M. (PI)
2011/04/01 → 2013/03/31
Project: Research
Research output
- 31 Article
-
The development of a highly sensitive and quantitative SARS-CoV-2 rapid antigen test applying newly developed monoclonal antibodies to an automated chemiluminescent flow-through membrane immunoassay device
Nishimura, K., Kitazawa, H., Kawahata, T., Yuhara, K., Masuya, T., Kuroita, T., Waki, K., Koike, S., Isobe, M. & Kurosawa, N., 2023/12, In: BMC Immunology. 24, 1, 34.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Novel super-neutralizing antibody UT28K is capable of protecting against infection from a wide variety of SARS-CoV-2 variants
Ozawa, T., Tani, H., Anraku, Y., Kita, S., Igarashi, E., Saga, Y., Inasaki, N., Kawasuji, H., Yamada, H., Sasaki, S. I., Somekawa, M., Sasaki, J., Hayakawa, Y., Yamamoto, Y., Morinaga, Y., Kurosawa, N., Isobe, M., Fukuhara, H., Maenaka, K. & Hashiguchi, T. & 4 others, , 2022, In: mAbs. 14, 1, 2072455.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Novel super-neutralizing antibody UT28K is capable of protecting against infection from a wide variety of SARS-CoV-2 variants
Ozawa, T., Tani, H., Anraku, Y., Kita, S., Igarashi, E., Saga, Y., Inasaki, N., Kawasuji, H., Yamada, H., Sasaki, S.-I., Somekawa, M., Sasaki, J., Hayakawa, Y., Yamamoto, Y., Morinaga, Y., Kurosawa, N., Isobe, M., Fukuhara, H., Maenaka, K. & Hashiguchi, T. & 4 others, , 2022/05/12, In: mAbs. 14, 1, p. 2072455Research output: Contribution to journal › Article › peer-review
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High throughput development of TCR-mimic antibody that targets survivin-2B80-88/HLA-A*A24 and its application in a bispecific T-cell engager
Kurosawa, N., Wakata, Y., Ida, K., Midorikawa, A. & Isobe, M., 2019/12/01, In: Scientific Reports. 9, 1, 9827.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
Novel method for the high-throughput production of phosphorylation site-specific monoclonal antibodies
Kurosawa, N., Wakata, Y., Inobe, T., Kitamura, H., Yoshioka, M., Matsuzawa, S., Kishi, Y. & Isobe, M., 2016/04/29, In: Scientific Reports. 6, 25174.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations
Datasets
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SARS-CoV-2 spike RBD in complex with neutralizing antibody UT28K
Ozawa, T. (Contributor), Tani, H. (Contributor), Anraku, Y. (Contributor), Kita, S. (Contributor), Igarashi, E. (Contributor), Saga, Y. (Contributor), Inasaki, N. (Contributor), Kawasuji, H. (Contributor), Yamada, H. (Contributor), Sasaki, S.-I. (Contributor), Somekawa, M. (Contributor), Sasaki, J. (Contributor), Hayakawa, Y. (Contributor), Yamamoto, Y. (Contributor), Morinaga, Y. (Contributor), Kurosawa, N. (Contributor), Isobe, M. (Contributor), Fukuhara, H. (Contributor), Maenaka, K. (Contributor), Hashiguchi, T. (Contributor), Kishi, H. (Contributor), Kitajima, I. (Contributor), Saito, S. (Contributor) & Niimi, H. (Contributor), Protein Data Bank (PDB), 2022/05/25
DOI: 10.2210/pdb7X7O/pdb, https://www.wwpdb.org/pdb?id=pdb_00007x7o
Dataset