Kazuto Shibuya - University of Toyama

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Research activity per year

Campus career

附属病院　助教　2012/04/01-2016/03/31
医学科　助教　2016/04/01-2019/09/30
分子病態医学系　助教　2016/04/01-2019/09/30
医学系　助教　2019/10/01-
医学科　助教　2019/10/01-
医学部医学科　基幹教員
学部運営への参画状況・・・有-医学科医学教育推進専門委員会
担当授業科目に係る状況・・・主要授業科目担当

Research interests

Na+,K+-ATPaseは原形質膜に存在し,細胞の膜電位を保つ重要なタンパク質である.このATPaseは,αおよびβサブユニットで構成され,αサブユニット(αNaK)にはα1からα4までのアイソフォームがある.ヒト肝細胞癌(HCC)ではαNaKとの関連についての報告はなく,本研究はHCCにおけるαNaKの発現変動および生理機能を明らかにすることを目的とした.その結果,HCCにおいてα3NaKは癌細胞の生存に寄与し,また治療のターゲットタンパク質になり得ると考えられた.

Research Fields, Keywords

gastroenterological surgery

Field of expertise (Grants-in-aid for Scientific Research classification)

Digestive surgery

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1 Similar Profiles

1 Finished

Study of searching of the new molecular target of the hepatocellular carcinoma overexpression of Na+,K+-ATPase
Shibuya, K. (PI)
2013/04/01 → 2015/03/31
Project: Research

51 Article
1 Comment/debate
1 Review article

A case of MSI-high pancreatic body-tail cancer successfully treated with radical resection after pembrolizumab
Ito, M., Watanabe, T., Oga, Y., Matsumoto, S., Kimura, N., Nagamori, M., Tanaka, H., Shibuya, K., Yoshioka, I. & Fujii, T., 2025/02, In: Clinical Journal of Gastroenterology. 18, 1, p. 208-213 6 p.
Research output: Contribution to journal › Article › peer-review
A case of successful conversion surgery for unresectable gallbladder cancer treated with durvalumab in combination with gemcitabine plus cisplatin
Araki, T., Muranushi, R., Takagi, K., Tanaka, H., Shibuya, K., Ando, T., Yoshioka, I., Hirabayashi, K., Yasuda, I. & Fujii, T., 2025/02, In: Clinical Journal of Gastroenterology. 18, 1, p. 161-168 8 p.
Research output: Contribution to journal › Article › peer-review
1 Scopus citations
Conversion Surgery for Pancreatic Cancer
Horikawa, M., Fukasawa, M., Machi, J., Urushihara, H., Furuhara, Y., Sunakawa, A., Yamamoto, K., Kusunoki, H., Kimura, N., Muranushi, R., Shirai, Y., Hirano, K., Watanabe, T., Shibuya, K., Yoshioka, I. & Fujii, T., 2025/01/01, In: Japanese Journal of Cancer and Chemotherapy. 52, 1, p. 19-24 6 p.
Research output: Contribution to journal › Article › peer-review
FUT2 and FUT3-specific normalization of DUPAN-2 and carbohydrate antigen 19-9 in preoperative therapy for pancreatic cancer: Multicentre retrospective study (GEMINI-PC-01)
Tanaka, H., Sakai, A., Suenaga, M., Hayashi, M., Otsu, T., Nakagawa, N., Kurimoto, K., Fukasawa, M., Shibuya, K., Watanabe, N., Sunagawa, M., Yamaguchi, J., Mizuno, T., Kokuryo, T., Takami, H., Ebata, T., Fujii, T. & Kodera, Y., 2025/04/01, In: British Journal of Surgery. 112, 4, znaf049.
Research output: Contribution to journal › Article › peer-review

Open Access
A case of BRCA1-mutated giant pancreatic acinar cell carcinoma successfully treated with modified FOLFIRINOX therapy and radical resection
Watanabe, T., Nagaoka, Y., Kimura, N., Fukasawa, M., Shirai, Y., Hirano, K., Shibuya, K., Yoshioka, I., Hamashima, T. & Fujii, T., 2024/10, In: Clinical Journal of Gastroenterology. 17, 5, p. 970-975 6 p.
Research output: Contribution to journal › Article › peer-review
1 Scopus citations

消化器疾患

Takahara, T., Kajiura, S., Minemura, M., Fujinami, H., Yoshioka, I., Shibuya, K., Hirano, K., Tajiri, K., Fujii, T., Yasuda, I., Okabe, M., Ando, T., Naruto, N., Miwa, T., Watanabe, T. & Shimada, S.

2024/10/01 → 2025/03/31

Course

内分泌・栄養・代謝・乳房

Tobe, K., Ishiki, M., Yoshioka, I., Okuno, N., Shibuya, K., Kitamura, H., Matsui, K., Fujii, T., Saitoh, J.-I., Chujo, D., Satake, T., Yanagisawa, S., Fujisaka, S. & Watanabe, T.

2024/04/01 → 2024/09/30

Course

第二外科
Sekine, S., Yoshioka, I., Shibuya, K., Hirano, K., Matsui, K., Fujii, T., Igarashi, T., Miwa, T., Watanabe, T. & Hashimoto, I.
2024/04/01 → 2025/03/31
Course
富山医療学
Inadera, H., Sekine, M., Inadera, H., Hayashi, A., Yoshimura, N., Tatsuse, T., Yamada, M., Nakashima, A., Minemura, M., Shibuya, K., Kinugawa, K. & Yasuda, I.
2023/10/01 → 2024/03/31
Course

消化器疾患

Minemura, M., Fujinami, H., Yoshioka, I., Shibuya, K., Hirano, K., Motoo, I., Tajiri, K., Fujii, T., Yasuda, I., Okabe, M., Ando, T., Naruto, N., Miwa, T., Watanabe, T., Hirabayashi, K., Hashimoto, I. & Watanabe, K.

2023/10/01 → 2024/03/31

Course