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Active
神経軸索伸長活性アルカロイドの創出を指向したアルカロイド生合成酵素の機能改変
Morita, H. (Principal Investigator)
Japan Society for the Promotion of Science
2025/04/01 → 2028/03/31
Project: Research Project
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FIHを標的とした代謝異常関連脂肪肝MAFLDの治療に有効なシード化合物の探索
Nakashima, Y. (Principal Investigator)
Japan Society for the Promotion of Science
2024/04/01 → 2026/03/31
Project: Research Project
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Investigation on naphthylisoquinoline alkaloids as potential antiausterity chemotherapy for pancreatic cancer
Awale, S. (Principal Investigator) & Fujii, T. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2023/04/01 → 2028/03/31
Project: Research Project
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Finished
Searching for effective anti-cancer seed compounds for refractory cancers targeting AspH
Nakashima, Y. (Principal Investigator)
Japan Society for the Promotion of Science
2022/04/01 → 2024/03/31
Project: Research Project
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AchE阻害活性アルカロイドの骨格生合成酵素の機能解析と改変
Morita, H. (Principal Investigator), 猛児玉 (Co-Investigator(Kenkyū-buntansha)) & Nakashima, Y. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2022/04/01 → 2025/03/31
Project: Research Project
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ポリケタイド閉環酵素とバイヤービリガー酵素の機能改変と新規化合物の創出
Morita, H. (Principal Investigator)
Japan Society for the Promotion of Science
2019/04/01 → 2021/03/31
Project: Public
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Engineering of DABB-family enzymes to novel polyketide cyclase
Morita, H. (CoI)
2017/04/01 → 2020/03/31
Project: Research
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植物由来新規ポリケタイド閉環酵素の探索と物質生産
Morita, H. (Principal Investigator)
Japan Society for the Promotion of Science
2017/04/01 → 2019/03/31
Project: Public
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カメルーン産薬用植物の抗菌活性成分に関する研究
Awouafack, M. D. (PI) & Morita, H. (CoI)
2016/11/07 → 2019/03/31
Project: Research
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Discovery of natural anticancer agents that inhibit cancer cells' tolerance to nutrition starvation and elucidation of their molecular mechanisms
Awale, S. (PI)
2016/04/01 → 2020/03/31
Project: Research
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Collection of new natural sources and analysis of their chemical constituents and construction of genetic resource bank
Morita, H. (PI), 伊藤卓也. (CoI) & Wong, C. P. (CoI)
2015/04/01 → 2019/03/31
Project: Research
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Investigation of pathogenic mechanisms and Kampo medicine-based preventive and therapeutic strategy for ADHD using an epigenetic animal model.
Matsumoto, K. (PI), Awale, S. (CoI), 藤原, 博典 (CoI) & Hori, E. (CoI)
2015/04/01 → 2018/03/31
Project: Research
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消化器癌に対する抗腫瘍和漢薬の確立および臨床応用に関する研究
Tsukada, K. (PI), Ohnaga, T. (CoI), Morita, H. (CoI) & Nagata, T. (CoI)
2015/04/01 → 2016/03/31
Project: Research
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ＦｔｓＺ阻害活性を基盤としたベトナム産植物中の抗生物質に関する研究
Morita, H. (PI) & Nguyen, H. T. (CoI)
2014/04/25 → 2017/03/31
Project: Research
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Engineering of plant-specific polyketide scaffold synthetic enzymes to produce structural diversity of compounds
Morita, H. (PI), Matsui, T. (CoI) & Kodama, T. (CoI)
2014/04/01 → 2017/03/31
Project: Research
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Engineering of type III polyketide synthase by deletion and addition of residues
Morita, H. (PI)
2014/04/01 → 2016/03/31
Project: Research
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インドールプレニル基転移酵素の動的立体構造基盤の確立と酵素触媒機能の拡張
Morita, H. (Principal Investigator)
Japan Society for the Promotion of Science
2013/04/01 → 2015/03/31
Project: Public
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Structural basis for plant-specific type III polyketide synthase based on the X-ray crystal structure analysis and computational chemistry
Morita, H. (PI)
2012/04/01 → 2014/03/31
Project: Research
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Search for the antiausterity agents induced metabolomic biomarkers associated with the tolerance of nutrition starvation in pancreatic cancer
Awale, S. (PI) & Esumi, H. (CoI)
2012/04/01 → 2016/03/31
Project: Research
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Development of a new pancreatic cancer curative medicine from arctigenin, an ingredient of Wakan-yaku 'Burdock Fruit (Seeds of Arctium lappa)'
Tezuka, Y. (PI), Toyooka, N. (CoI) & Awale, S. (CoI)
2010/04/01 → 2013/03/31
Project: Research