Asymmetric synthesis of 1-alkyl-2-deoxyiminofuranoses via the iridium-catalyzed intramolecular cyclization of an allylic carbonate

Yoshihiro Natori; Shunsuke Kikuchi; Yuichi Yoshimura; Atsushi Kato; Isao Adachi; Hiroki Takahata

doi:10.3987/COM-12-S(N)99

Asymmetric synthesis of 1-alkyl-2-deoxyiminofuranoses via the iridium-catalyzed intramolecular cyclization of an allylic carbonate

Yoshihiro Natori, Shunsuke Kikuchi, Yuichi Yoshimura, Atsushi Kato, Isao Adachi, Hiroki Takahata

薬剤部

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

9 被引用数 (Scopus)

抄録

An asymmetric synthesis of 1-alkyl-2-deoxyiminofuranoses was achieved in which the Ir-catalyzed intramolecular cyclization was the key step. The diastereoselective cyclization converted an allylic carbonate into pyrrolidine derivatives. The a-glucosidase inhibitory activities of the prepared 2-deoxyiminofuranoses were also investigated.

本文言語	英語
ページ（範囲）	1401-1417
ページ数	17
ジャーナル	Heterocycles
巻	86
号	2
DOI	https://doi.org/10.3987/COM-12-S(N)99
出版ステータス	出版済み - 2012

ASJC Scopus 主題領域

分析化学
薬理学
有機化学

文献へのアクセス

10.3987/COM-12-S(N)99

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引用スタイル

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abstract = "An asymmetric synthesis of 1-alkyl-2-deoxyiminofuranoses was achieved in which the Ir-catalyzed intramolecular cyclization was the key step. The diastereoselective cyclization converted an allylic carbonate into pyrrolidine derivatives. The a-glucosidase inhibitory activities of the prepared 2-deoxyiminofuranoses were also investigated.",

author = "Yoshihiro Natori and Shunsuke Kikuchi and Yuichi Yoshimura and Atsushi Kato and Isao Adachi and Hiroki Takahata",

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AU - Natori, Yoshihiro

AU - Kikuchi, Shunsuke

AU - Yoshimura, Yuichi

AU - Kato, Atsushi

AU - Adachi, Isao

AU - Takahata, Hiroki

PY - 2012

Y1 - 2012

N2 - An asymmetric synthesis of 1-alkyl-2-deoxyiminofuranoses was achieved in which the Ir-catalyzed intramolecular cyclization was the key step. The diastereoselective cyclization converted an allylic carbonate into pyrrolidine derivatives. The a-glucosidase inhibitory activities of the prepared 2-deoxyiminofuranoses were also investigated.

AB - An asymmetric synthesis of 1-alkyl-2-deoxyiminofuranoses was achieved in which the Ir-catalyzed intramolecular cyclization was the key step. The diastereoselective cyclization converted an allylic carbonate into pyrrolidine derivatives. The a-glucosidase inhibitory activities of the prepared 2-deoxyiminofuranoses were also investigated.

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M3 - 学術論文

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