年別の研究成果
年別の研究成果
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2025
Bromocriptine improves glucose tolerance in obese mice via central dopamine D2 receptor-independent mechanism
Tsuneki, H., Maeda, T., Takatsuki, M., Sekine, T., Masui, S., Onishi, K., Takeda, R., Sugiyama, M., Sakurai, T., Yanagisawa, M., Wada, T. & Sasaoka, T., 2025/03, In: PLoS ONE. 20, 3 March, e0320157.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access -
2024
C-terminal peptide of preproorexin enhances brain-derived neurotrophic factor expression in rat cerebrocortical cells and recognition memory in mice
Tsuneki, H., Honda, K., Sekine, Y., Yahata, K., Yasue, M., Fujishima, M., Takeda, R., Wada, T. & Sasaoka, T., 2024/02/05, In: European Journal of Pharmacology. 964, 176306.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access1 被引用数 (Scopus) -
Deletion of platelet-derived growth factor receptor β suppresses tumorigenesis in metabolic dysfunction-associated steatohepatitis (MASH) mice with diabetes
Wada, T., Takeda, Y., Okekawa, A., Komatsu, G., Iwasa, Y., Onogi, Y., Takasaki, I., Hamashima, T., Sasahara, M., Tsuneki, H. & Sasaoka, T., 2024/12, In: Scientific Reports. 14, 1, 23829.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access -
Platelet-derived growth factor signaling in pericytes promotes hypothalamic inflammation and obesity
Okekawa, A., Wada, T., Onogi, Y., Takeda, Y., Miyazawa, Y., Sasahara, M., Tsuneki, H. & Sasaoka, T., 2024/12, In: Molecular Medicine. 30, 1, 21.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access4 被引用数 (Scopus) -
2023
A transdermal treatment with MC903 ameliorates diet-induced obesity by reducing visceral fat and increasing myofiber thickness and energy consumption in mice
Wada, T., Miyazawa, Y., Ikurumi, M., Fuse, K., Okekawa, A., Onogi, Y., Saito, S., Tsuneki, H. & Sasaoka, T., 2023/12, In: Nutrition and Metabolism. 20, 1, 10.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access2 被引用数 (Scopus) -
2022
Ebselen enhances insulin sensitivity and decreases oxidative stress by inhibiting SHIP2 and protects from inflammation in diabetic mice
Polianskyte-Prause, Z., Tolvanen, T. A., Lindfors, S., Kon, K., Hautala, L. C., Wang, H., Wada, T., Tsuneki, H., Sasaoka, T. & Lehtonen, S., 2022, In: International Journal of Biological Sciences. 18, 5, p. 1852-1864 13 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access17 被引用数 (Scopus) -
Food odor perception promotes systemic lipid utilization
Tsuneki, H., Sugiyama, M., Ito, T., Sato, K., Matsuda, H., Onishi, K., Yubune, K., Matsuoka, Y., Nagai, S., Yamagishi, T., Maeda, T., Honda, K., Okekawa, A., Watanabe, S., Yaku, K., Okuzaki, D., Otsubo, R., Nomoto, M., Inokuchi, K. & Nakagawa, T. & 3 others, , 2022/11, In: Nature Metabolism. 4, 11, p. 1514-1531 18 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
19 被引用数 (Scopus) -
Food odor perception promotes systemic lipid utilization
Tsuneki, H., Sugiyama, M., Ito, T., Sato, K., Matsuda, H., Onishi, K., Yubune, K., Matsuoka, Y., Nagai, S., Yamagishi, T., Maeda, T., Honda, K., Okekawa, A., Watanabe, S., Yaku, K., Okuzaki, D., Otsubo, R., Nomoto, M., Inokuchi, K. & Nakagawa, T. & 3 others, , 2022/11, In: Nature Metabolism. 4, 11, p. 1514-1531研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
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Hypothalamic orexin prevents non-alcoholic steatohepatitis and hepatocellular carcinoma in obesity
Tsuneki, H., Maeda, T., Takata, S., Sugiyama, M., Otsuka, K., Ishizuka, H., Onogi, Y., Tokai, E., Koshida, C., Kon, K., Takasaki, I., Hamashima, T., Sasahara, M., Rudich, A., Koya, D., Sakurai, T., Yanagisawa, M., Yamanaka, A., Wada, T. & Sasaoka, T., 2022/10/18, In: Cell Reports. 41, 3, 111497.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access16 被引用数 (Scopus) -
2021
Human adipose tissue is a putative direct target of daytime orexin with favorable metabolic effects: A cross-sectional study
Goldstein, N., Tsuneki, H., Bhandarkar, N., Aimaretti, E., Haim, Y., Kon, K., Sato, K., Wada, T., Liberty, I. F., Kirshtein, B., Dukhno, O., Maixner, N., Gepner, Y., Sasaoka, T. & Rudich, A., 2021/11, In: Obesity. 29, 11, p. 1857-1867 11 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
4 被引用数 (Scopus) -
Oestrogen receptor α in T cells controls the T cell immune profile and glucose metabolism in mouse models of gestational diabetes mellitus
Tanaka, T., Wada, T., Uno, K., Ogihara, S., Ie, H., Okekawa, A., Ishikawa, A., Ito, T., Miyazawa, Y., Sameshima, A., Onogi, Y., Tsuneki, H., Sasahara, M., Nakashima, A., Saito, S. & Sasaoka, T., 2021/07, In: Diabetologia. 64, 7, p. 1660-1673 14 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access10 被引用数 (Scopus) -
Total synthesis of decahydroquinoline poison frog alkaloids ent-cis-195a and cis-211a
Okada, T., Wu, N., Takashima, K., Ishimura, J., Morita, H., Ito, T., Kodama, T., Yamasaki, Y., Akanuma, S. I., Kubo, Y., Hosoya, K. I., Tsuneki, H., Wada, T., Sasaoka, T., Shimizu, T., Sakai, H., Dwoskin, L. P., Hussaini, S. R., Saporito, R. A. & Toyooka, N., 2021/12/01, In: Molecules. 26, 24, 7529.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access7 被引用数 (Scopus) -
Type 1 diabetes woman with repeated miscarriages successfully gave birth after introducing an insulin pump with a predictive low glucose suspend feature
Honoki, H., Yagi, K., Tsuda, S., Wada, T., Enkaku, A., Nakagawa-Yokoyama, M., Kamigishi, M., Shikata, M., Takikawa-Nishiday, A., Fujisaka, S., Chujo, D., Sasaoka, T., Nakashima, A., Saito, S. & Tobe, K., 2021/07, In: Diabetology International. 12, 3, p. 324-329 6 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access1 被引用数 (Scopus) -
2020
Astaxanthin stimulates mitochondrial biogenesis in insulin resistant muscle via activation of AMPK pathway
Nishida, Y., Nawaz, A., Kado, T., Takikawa, A., Igarashi, Y., Onogi, Y., Wada, T., Sasaoka, T., Yamamoto, S., Sasahara, M., Imura, J., Tokuyama, K., Usui, I., Nakagawa, T., Fujisaka, S., Kunimasa, Y. & Tobe, K., 2020/02/01, In: Journal of Cachexia, Sarcopenia and Muscle. 11, 1, p. 241-258 18 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access116 被引用数 (Scopus) -
Estrogen regulates sex-specific localization of regulatory T cells in adipose tissue of obese female mice
Ishikawa, A., Wada, T., Nishimura, S., Ito, T., Okekawa, A., Onogi, Y., Watanabe, E., Sameshima, A., Tanaka, T., Tsuneki, H., Saito, S. & Sasaoka, T., 2020, In: PLoS ONE. 15, 4, e0230885.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access32 被引用数 (Scopus) -
Pro-inflammatory macrophages coupled with glycolysis remodel adipose vasculature by producing platelet-derived growth factor-B in obesity
Onogi, Y., Wada, T., Okekawa, A., Matsuzawa, T., Watanabe, E., Ikeda, K., Nakano, M., Kitada, M., Koya, D., Tsuneki, H. & Sasaoka, T., 2020/12/01, In: Scientific Reports. 10, 1, 670.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access25 被引用数 (Scopus) -
Stromal cell-derived factor 1 (SDF1) attenuates platelet-derived growth factor-B (PDGF-B)-induced vascular remodeling for adipose tissue expansion in obesity
Watanabe, E., Wada, T., Okekawa, A., Kitamura, F., Komatsu, G., Onogi, Y., Yamamoto, S., Sasahara, M., Kitada, M., Koya, D., Tsuneki, H. & Sasaoka, T., 2020/11/01, In: Angiogenesis. 23, 4, p. 667-684 18 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
24 被引用数 (Scopus) -
2019
AS1949490, an inhibitor of 5′-lipid phosphatase SHIP2, promotes protein kinase C-dependent stabilization of brain-derived neurotrophic factor mRNA in cultured cortical neurons
Tsuneki, H., Yoshida, H., Okamoto, K., Yamaguchi, M., Endo, K., Nakano, A., Tsuda, M., Toyooka, N., Wada, T. & Sasaoka, T., 2019/05/15, In: European Journal of Pharmacology. 851, p. 69-79 11 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access4 被引用数 (Scopus) -
Chronotherapeutic effect of orexin antagonists on glucose metabolism in diabetic mice
Kon, K., Tsuneki, H., Ito, H., Takemura, Y., Sato, K., Yamazaki, M., Ishii, Y., Sasahara, M., Rudich, A., Maeda, T., Wada, T. & Sasaoka, T., 2019/10, In: Journal of Endocrinology. 243, 1, p. 59-72 14 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access6 被引用数 (Scopus) -
Role of angiogenesis and chronic inflammation in fat hypertrophy in NASH pathology
Wada, T., Tsuneki, H. & Sasaoka, T., 2019, In: Yakugaku Zasshi. 139, 9, p. 1163-1167 5 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access4 被引用数 (Scopus) -
2018
Chronopathophysiological implications of orexin in sleep disturbances and lifestyle-related disorders
Tsuneki, H., Wada, T. & Sasaoka, T., 2018/06, In: Pharmacology and Therapeutics. 186, p. 25-44 20 p.研究成果: ジャーナルへの寄稿 › 総説 › 査読
25 被引用数 (Scopus) -
2017
Eplerenone prevented obesity-induced inflammasome activation and glucose intolerance
Wada, T., Ishikawa, A., Watanabe, E., Nakamura, Y., Aruga, Y., Hasegawa, H., Onogi, Y., Honda, H., Nagai, Y., Takatsu, K., Ishii, Y., Sasahara, M., Koya, D., Tsuneki, H. & Sasaoka, T., 2017/12/01, In: Journal of Endocrinology. 235, 3, p. 179-191 13 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access51 被引用数 (Scopus) -
PDGFRβ regulates adipose tissue expansion and glucose metabolism via vascular remodeling in diet-induced obesity
Onogi, Y., Wada, T., Kamiya, C., Inata, K., Matsuzawa, T., Inaba, Y., Kimura, K., Inoue, H., Yamamoto, S., Ishii, Y., Koya, D., Tsuneki, H., Sasahara, M. & Sasaoka, T., 2017/04/01, In: Diabetes. 66, 4, p. 1008-1021 14 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
67 被引用数 (Scopus) -
2016
Nighttime administration of nicotine improves hepatic glucose metabolism via the hypothalamic orexin system in mice
Tsuneki, H., Nagata, T., Fujita, M., Kon, K., Wu, N., Takatsuki, M., Yamaguchi, K., Wada, T., Nishijo, H., Yanagisawa, M., Sakurai, T. & Sasaoka, T., 2016/01, In: Endocrinology. 157, 1, p. 195-206 12 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access17 被引用数 (Scopus) -
Timed inhibition of orexin system by suvorexant improved sleep and glucose metabolism in type 2 diabetic db/db mice
Tsuneki, H., Kon, K., Ito, H., Yamazaki, M., Takahara, S., Toyooka, N., Ishii, Y., Sasahara, M., Wada, T., Yanagisawa, M., Sakurai, T. & Sasaoka, T., 2016/11, In: Endocrinology. 157, 11, p. 4146-4157 12 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access24 被引用数 (Scopus) -
2015
Hypothalamic orexin prevents hepatic insulin resistance via daily bidirectional regulation of autonomic nervous system in mice
Tsuneki, H., Tokai, E., Nakamura, Y., Takahashi, K., Fujita, M., Asaoka, T., Kon, K., Anzawa, Y., Wada, T., Takasaki, I., Kimura, K., Inoue, H., Yanagisawa, M., Sakurai, T. & Sasaoka, T., 2015/02/01, In: Diabetes. 64, 2, p. 459-470 12 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access61 被引用数 (Scopus) -
Orexin regulates glucose homeodynamics with daily rhythm
Tsuneki, H., Wada, T. & Sasaoka, T., 2015/09/22, Orexin and Sleep: Molecular, Functional and Clinical Aspects. Springer International Publishing, p. 381-394 14 p.研究成果: 書籍の章/レポート/会議録 › 章 › 査読
1 被引用数 (Scopus) -
Teneligliptin improves metabolic abnormalities in a mouse model of postmenopausal obesity
Sameshima, A., Wada, T., Ito, T., Kashimura, A., Sawakawa, K., Yonezawa, R., Tsuneki, H., Ishii, Y., Sasahara, M., Saito, S. & Sasaoka, T., 2015, In: Journal of Endocrinology. 227, 1, p. 25-36 12 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access11 被引用数 (Scopus) -
2013
Cilostazol ameliorates systemic insulin resistance in diabetic db/db mice by suppressing chronic inflammation in adipose tissue via modulation of both adipocyte and macrophage functions
Wada, T., Onogi, Y., Kimura, Y., Nakano, T., Fusanobori, H., Ishii, Y., Sasahara, M., Tsuneki, H. & Sasaoka, T., 2013/05/05, In: European Journal of Pharmacology. 707, 1-3, p. 120-129 10 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
36 被引用数 (Scopus) -
Eplerenone ameliorates the phenotypes of metabolic syndrome with NASH in liver-specific SREBP-1c Tg mice fed high-fat and high-fructose diet
Wada, T., Miyashita, Y., Sasaki, M., Aruga, Y., Nakamura, Y., Ishii, Y., Sasahara, M., Kanasaki, K., Kitada, M., Koya, D., Shimano, H., Tsuneki, H. & Sasaoka, T., 2013/12/01, In: American Journal of Physiology - Endocrinology and Metabolism. 305, 11, p. E1415-E1425研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
66 被引用数 (Scopus) -
Hypothalamic orexin prevents hepatic insulin resistance induced by social defeat stress in mice
Tsuneki, H., Tokai, E., Sugawara, C., Wada, T., Sakurai, T. & Sasaoka, T., 2013/06, In: Neuropeptides. 47, 3, p. 213-219 7 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
30 被引用数 (Scopus) -
Impact of divergent effects of astaxanthin on insulin signaling in L6 cells
Ishiki, M., Nishida, Y., Ishibashi, H., Wada, T., Fujisaka, S., Takikawa, A., Urakaze, M., Sasaoka, T., Usui, I. & Tobe, K., 2013/08/01, In: Endocrinology. 154, 8, p. 2600-2612 13 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access76 被引用数 (Scopus) -
New insights into metabolic regulation via bifurcated function of estrogen receptor a
Wada, T., Tsuneki, H. & Sasaoka, T., 2013/12, In: Diabetes. 62, 12, p. 3996-3998 3 p.研究成果: ジャーナルへの寄稿 › コメント/討論
Open Access6 被引用数 (Scopus) -
Rational design and synthesis of 4-substituted 2-pyridin-2-ylamides with inhibitory effects on SH2 domain-containing inositol 5′-phosphatase 2 (SHIP2)
Ichihara, Y., Fujimura, R., Tsuneki, H., Wada, T., Okamoto, K., Gouda, H., Hirono, S., Sugimoto, K., Matsuya, Y., Sasaoka, T. & Toyooka, N., 2013/04, In: European Journal of Medicinal Chemistry. 62, p. 649-660 12 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
24 被引用数 (Scopus) -
SH2-Containing Inositol 5′-Phosphatase 2 Selectively Impairs Hypothalamic Insulin Signalling and Regulation of Food Intake in Mice
Ichihara, Y., Wada, T., Soeda, Y., Ishii, Y., Sasahara, M., Tsuneki, H. & Sasaoka, T., 2013/04, In: Journal of Neuroendocrinology. 25, 4, p. 372-382 11 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
6 被引用数 (Scopus) -
2012
Central versus peripheral impact of estradiol on the impaired glucose metabolism in ovariectomized mice on a high-fat diet
Yonezawa, R., Wada, T., Matsumoto, N., Morita, M., Sawakawa, K., Ishii, Y., Sasahara, M., Tsuneki, H., Saito, S. & Sasaoka, T., 2012/08/15, In: American Journal of Physiology - Endocrinology and Metabolism. 303, 4, p. E445-E456研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
80 被引用数 (Scopus) -
Role of orexin in the central regulation of glucose and energy homeostasis
Tsuneki, H., Wada, T. & Sasaoka, T., 2012, In: Endocrine Journal. 59, 5, p. 365-374 10 p.研究成果: ジャーナルへの寄稿 › 総説 › 査読
Open Access56 被引用数 (Scopus) -
Synthesis and biological activities of the 3,5-disubstituted indolizidine poison frog alkaloid 239Q and its congeners
Wang, X., Tsuneki, H., Urata, N., Tezuka, Y., Wada, T., Sasaoka, T., Sakai, H., Saporito, R. A. & Toyooka, N., 2012/12, In: European Journal of Organic Chemistry. 36, p. 7082-7092 11 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
15 被引用数 (Scopus) -
The radioprotective 105/MD-1 complex contributes to diet-induced obesity and adipose tissue inflammation
Watanabe, Y., Nakamura, T., Ishikawa, S., Fujisaka, S., Usui, I., Tsuneyama, K., Ichihara, Y., Wada, T., Hirata, Y., Suganami, T., Izaki, H., Akira, S., Miyake, K., Kanayama, H. O., Shimabukuro, M., Sata, M., Sasaoka, T., Ogawa, Y., Tobe, K. & Takatsu, K. & 1 others, , 2012/05, In: Diabetes. 61, 5, p. 1199-1209 11 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access41 被引用数 (Scopus) -
2010
Progesterone inhibits glucose uptake by affecting diverse steps of insulin signaling in 3T3-L1 adipocytes
Wada, T., Hori, S., Sugiyama, M., Fujisawa, E., Nakano, T., Tsuneki, H., Nagira, K., Saito, S. & Sasaoka, T., 2010/04, In: American Journal of Physiology - Endocrinology and Metabolism. 298, 4, p. E881-E888研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
66 被引用数 (Scopus) -
Role of orexin in the regulation of glucose homeostasis
Tsuneki, H., Wada, T. & Sasaoka, T., 2010/03, In: Acta Physiologica. 198, 3, p. 335-348 14 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
65 被引用数 (Scopus) -
Spironolactone improves glucose and lipid metabolism by ameliorating hepatic steatosis and inflammation and suppressing enhanced gluconeogenesis induced by high-fat and high-fructose diet
Wada, T., Kenmochi, H., Miyashita, Y., Sasaki, M., Ojima, M., Sasahara, M., Koya, D., Tsuneki, H. & Sasaoka, T., 2010/05, In: Endocrinology. 151, 5, p. 2040-2049 10 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access169 被引用数 (Scopus) -
The inositol phosphatase SHIP2 negatively regulates insulin/IGF-I actions implicated in neuroprotection and memory function in mouse brain
Soeda, Y., Tsuneki, H., Muranaka, H., Mori, N., Hosoh, S., Ichihara, Y., Kagawa, S., Wang, X., Toyooka, N., Takamura, Y., Uwano, T., Nishijo, H., Wada, T. & Sasaoka, T., 2010/10, In: Molecular Endocrinology. 24, 10, p. 1965-1977 13 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access35 被引用数 (Scopus) -
2009
Impact of Lipid phosphatases ship2 and pten on the time-and akt-isoform-specific amelioration of tNF-α-induced insulin resistance in 3T3-L1 adipocytes
Ikubo, M., Wada, T., Fukui, K., Ishiki, M., Ishihara, H., Asano, T., Tsuneki, H. & Sasaoka, T., 2009/01, In: American Journal of Physiology - Endocrinology and Metabolism. 296, 1, p. E157-E164研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
15 被引用数 (Scopus) -
Synthesis, determination of the absolute stereochemistry, and evaluations at the nicotinic acetylcholine receptors of a hydroxyindolizidine alkaloid from the ant Myrmicaria melanogaster
Zhou, D., Toyooka, N., Nemoto, H., Yamaguchi, K., Tsuneki, H., Wada, T., Sasaoka, T., Sakai, H., Tezuka, Y., Kadota, S., Jones, T. H., Garraffo, H. M., Spande, T. F. & Daly, J. W., 2009, In: Heterocycles. 79, C, p. 565-571 7 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access5 被引用数 (Scopus) -
2008
Age-related insulin resistance in hypothalamus and peripheral tissues of orexin knockout mice
Tsuneki, H., Murata, S., Anzawa, Y., Soeda, Y., Tokai, E., Wada, T., Kimura, I., Yanagisawa, M., Sakurai, T. & Sasaoka, T., 2008/04, In: Diabetologia. 51, 4, p. 657-667 11 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access114 被引用数 (Scopus) -
Impact of transgenic overexpression of SH2-containing inositol 5′-phosphatase 2 on glucose metabolism and insulin signaling in mice
Kagawa, S., Soeda, Y., Ishihara, H., Oya, T., Sasahara, M., Yaguchi, S., Oshita, R., Wada, T., Tsuneki, H. & Sasaoka, T., 2008/02, In: Endocrinology. 149, 2, p. 642-650 9 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access55 被引用数 (Scopus) -
Syntheses of the proposed structures of poison-frog alkaloids 179 and 207E and their inhibitory effects on neuronal nicotinic acetylcholine receptors
Toyooka, N., Zhou, D., Kobayashi, S., Tsuneki, H., Wada, T., Sakai, H., Nemoto, H., Sasaoka, T., Tezuka, Y., Subehan, Kadota, S., Garraffo, H. M., Spande, T. F. & Daly, J. W., 2008/01/03, In: Synlett. 1, p. 61-64 4 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
11 被引用数 (Scopus) -
2007
Chronic nicotine exposure enhances insulin-induced mitogenic signaling via up-regulation of α7 nicotinic receptors in isolated rat aortic smooth muscle cells
Wada, T., Naito, M., Kenmochi, H., Tsuneki, H. & Sasaoka, T., 2007/02, In: Endocrinology. 148, 2, p. 790-799 10 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access54 被引用数 (Scopus) -
Flexible synthesis of poison-frog alkaloids of the 5,8-disubstituted indolizidine-class. II: Synthesis of (-)-209B, (-)-231C, (-)-233D, (-)-235B''", (-)-22II, and an epimer of 193E and pharmacological effects at neuronal nicotinic acetylcholine receptors
Kobayashi, S., Toyooka, N., Zhou, D., Tsuneki, H., Wada, T., Sasaoka, T., Sakai, H., Nemoto, H., Garraffo, H. M., Spande, T. F. & Daly, J. W., 2007, In: Beilstein Journal of Organic Chemistry. 3, 30.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access17 被引用数 (Scopus)