Daisuke Uta

2025

Biotinylated Heptapeptides with D-amino Acids Suppress Allergic Reactions by Inhibiting Mast Cell Activation and Antagonizing the Histamine Receptor

Ohira, M., Uwamizu, A., Hori, K., Obinata, Y., Uta, D., Aoki, J., Ebina, K., Matsumoto, T. & Sato, A., 2025/01, In: International Journal of Peptide Research and Therapeutics. 31, 1, 9.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Potassium/Sodium Citrate Attenuates Paclitaxel-Induced Peripheral Neuropathy

Uta, D., Nakamura, H., Maruo, K., Matsumura, K., Usami, Y. & Kume, T., 2025/04, In: International Journal of Molecular Sciences. 26, 7, 3329.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

2024

Actions of remimazolam on inhibitory transmission of rat spinal dorsal horn neurons

Hoshino, R., Ohashi, N., Uta, D., Ohashi, M., Deguchi, H. & Baba, H., 2024/06, In: Journal of Pharmacological Sciences. 155, 2, p. 63-73 11 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

2 被引用数 (Scopus)

Amitriptyline and duloxetine attenuate activities of superficial dorsal horn neurons in a rat reserpine-induced fibromyalgia model

Uta, D., Tsuboshima, K., Mizumura, K., Nishijo, H. & Taguchi, T., 2024/11, In: Journal of Pharmacological Sciences. 156, 3, p. 180-187 8 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

Combined effect of Neurotropin® and methylcobalamin on postherpetic neuralgia in mice infected with herpes simplex virus type-1

Andoh, T., Kikukawa, T., Kotani, A., Kurokawa, Y., Asakura, W., Houmoto, K., Fukutomi, D., Uta, D., Okai, H. & Koike, K., 2024/03, In: Journal of Dermatological Science. 113, 3, p. 138-147 10 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

4 被引用数 (Scopus)

Combined Experiments with in Vivo Fiber Photometry and Behavior Tests Can Facilitate the Measurement of Neuronal Activity in the Primary Somatosensory Cortex and Hyperalgesia in an Inflammatory Pain Mice Model

Ishikawa, T., Uta, D., Okuda, H., Potapenko, I., Hori, K., Kume, T. & Ozaki, N., 2024/03, In: Biological and Pharmaceutical Bulletin. 47, 3, p. 591-599 9 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

1 被引用数 (Scopus)

Mirogabalin inhibits scratching behavior of spontaneous model mouse of atopic dermatitis

Matsuda, K., Kitano, Y., Sawahata, M., Kume, T. & Uta, D., 2024/06/26, In: Frontiers in Pharmacology. 15

研究成果: ジャーナルへの寄稿 › 学術論文

1 被引用数 (Scopus)

Omega-conotoxin MVIIA reduces neuropathic pain after spinal cord injury by inhibiting N-type voltage-dependent calcium channels on spinal dorsal horn

Ohashi, N., Uta, D., Ohashi, M., Hoshino, R. & Baba, H., 2024, In: Frontiers in Neuroscience. 18, 1366829.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

3 被引用数 (Scopus)

Photobiomodulation inhibits neuronal firing in the superficial but not deep layer of a rat spinal dorsal horn

Uta, D., Ishibashi, N., Tao, S., Sawahata, M. & Kume, T., 2024/05/28, In: Biochemical and Biophysical Research Communications. 710, 149873.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

5 被引用数 (Scopus)

Photobiomodulation transiently increases the spontaneous firing in the superficial layer of the rat spinal dorsal horn

Ishibashi, N., Uta, D., Sawahata, M. & Kume, T., 2024/10, In: Biochemical and Biophysical Research Communications. 729, p. 150362-150362 1 p.

研究成果: ジャーナルへの寄稿 › 学術論文

1 被引用数 (Scopus)

2023

Effect of a Single Dose of Oxaliplatin on the Induction of Peripheral Neuropathy in a Rat Model: An in Vivo Electrophysiological Study

Uta, D., Takeuchi, K., Fukano, K., Kawamura, H. & Ito, A., 2023/08, In: Biological and Pharmaceutical Bulletin. 46, 8, p. 1128-1132 5 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

2 被引用数 (Scopus)

Near-Infrared Photobiomodulation of the Peripheral Nerve Inhibits the Neuronal Firing in a Rat Spinal Dorsal Horn Evoked by Mechanical Stimulation

Uta, D., Ishibashi, N., Konno, T., Okada, Y., Kawase, Y., Tao, S. & Kume, T., 2023/02, In: International Journal of Molecular Sciences. 24, 3, 2352.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

9 被引用数 (Scopus)

Periostin activates distinct modules of inflammation and itching downstream of the type 2 inflammation pathway

Nunomura, S., Uta, D., Kitajima, I., Nanri, Y., Matsuda, K., Ejiri, N., Kitajima, M., Ikemitsu, H., Koga, M., Yamamoto, S., Honda, Y., Takedomi, H., Andoh, T., Conway, S. J. & Izuhara, K., 2023/01/31, In: Cell Reports. 42, 1, 111933.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

15 被引用数 (Scopus)

Relationship between Laser Intensity at the Peripheral Nerve and Inhibitory Effect of Percutaneous Photobiomodulation on Neuronal Firing in a Rat Spinal Dorsal Horn

Uta, D., Ishibashi, N., Kawase, Y., Tao, S., Sawahata, M. & Kume, T., 2023/08, In: Journal of Clinical Medicine. 12, 15, 5126.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

6 被引用数 (Scopus)

2022

Analgesic effect of ivabradine against inflammatory pain mediated by hyperpolarization-activated cyclic nucleotide-gated cation channels expressed on primary afferent terminals in the spinal dorsal horn

Ohashi, N., Uta, D., Ohashi, M. & Baba, H., 2022/07/01, In: Pain. 163, 7, p. 1356-1369 14 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

6 被引用数 (Scopus)

APP Knock-In Mice Produce E22P-Aβ Exhibiting an Alzheimer’s Disease-like Phenotype with Dysregulation of Hypoxia-Inducible Factor Expression

Maki, T., Sawahata, M., Akutsu, I., Amaike, S., Hiramatsu, G., Uta, D., Izuo, N., Shimizu, T., Irie, K. & Kume, T., 2022/11, In: International Journal of Molecular Sciences. 23, 21, 13259.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

8 被引用数 (Scopus)

Histamine enhances ATP-induced itching and responsiveness to ATP in keratinocytes

Inami, Y., Fukushima, M., Kume, T. & Uta, D., 2022/02, In: Journal of Pharmacological Sciences. 148, 2, p. 255-261 7 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

8 被引用数 (Scopus)

Inhibition of transient receptor potential vanilloid 1 and transient receptor potential ankyrin 1 by mosquito and mouse saliva

Derouiche, S., Li, T., Sakai, Y., Uta, D., Aoyagi, S. & Tominaga, M., 2022/02/01, In: Pain. 163, 2, p. 299-307 9 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

4 被引用数 (Scopus)

Involvement of Histamine H₃ Receptor Agonism in Premature Ejaculation Found by Studies in Rats

Kiyohara, K., Uta, D., Nagaoka, Y., Kino, Y., Nonaka, H., Ninomiya‐baba, M. & Fujita, T., 2022/02/01, In: International Journal of Molecular Sciences. 23, 4, 2291.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

2 被引用数 (Scopus)

Nociceptive chemical hypersensitivity in the spinal cord of a rat reserpine-induced fibromyalgia model

Ejiri, Y., Uta, D., Ota, H., Mizumura, K. & Taguchi, T., 2022/08, In: Neuroscience Research. 181, p. 87-94 8 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

11 被引用数 (Scopus)

2021

Analyses of the mode of action of an alpha-adrenoceptor blocker in substantia gelatinosa neurons in rats

Uta, D., Hattori, T. & Yoshimura, M., 2021/09, In: International Journal of Molecular Sciences. 22, 17, 9636.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

Chemogenetic activation of central gastrin-releasing peptide-expressing neurons elicits itch-related scratching behavior in male and female mice

Kiguchi, N., Fukazawa, Y., Saika, A., Uta, D., Saika, F., Nakamura, T. Y., Ko, M. C. & Kishioka, S., 2021/06, In: Pharmacology Research and Perspectives. 9, 3, e00790.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

6 被引用数 (Scopus)

Estrogens influence female itch sensitivity via the spinal gastrin-releasing peptide receptor neurons

Takanami, K., Uta, D., Matsuda, K. I., Kawata, M., Carstens, E., Sakamoto, T. & Sakamoto, H., 2021/08/03, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 31, e2103536118.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

15 被引用数 (Scopus)

Inhibitory effect of panaxytriol on BV-2 microglial cell activation

Hiramatsu, G., Uta, D., Mihara, K., Andoh, T. & Kume, T., 2021/03, In: Journal of Pharmacological Sciences. 145, 3, p. 273-278 6 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

16 被引用数 (Scopus)

L-bupivacaine Inhibition of Nociceptive Transmission in Rat Peripheral and Dorsal Horn Neurons

Uta, D., Koga, K., Furue, H., Imoto, K. & Yoshimura, M., 2021/01/01, In: Anesthesiology. 134, 1, p. 88-102 15 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

17 被引用数 (Scopus)

Oxytocin Influences Male Sexual Activity via Non-synaptic Axonal Release in the Spinal Cord

Oti, T., Satoh, K., Uta, D., Nagafuchi, J., Tateishi, S., Ueda, R., Takanami, K., Young, L. J., Galione, A., Morris, J. F., Sakamoto, T. & Sakamoto, H., 2021/01/11, In: Current Biology. 31, 1, p. 103-114.e5

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

48 被引用数 (Scopus)

Panaxytriol inhibits lipopolysaccharide-induced microglia activation in brain inflammation in vivo

Hiramatsu, G., Matsuda, K., Uta, D., Mihara, K. & Kume, T., 2021/07, In: Biological and Pharmaceutical Bulletin. 44, 7, p. 1024-1028 5 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

8 被引用数 (Scopus)

2020

A puncturing device that mimics the mechanism of mosquito’s proboscis and labium – Verification of the effect of skin deformation / needle buckling prevention mechanism and puncture experiment on artificial skin and experimental animals

Yamamoto, S., Aoyagi, S., Yamada, M., Takahashi, T., Suzuki, M., Nagashima, T., Kunugi, A., Chiyonobu, M., Kuroiwa, T., Hosomi, R., Fukunaga, K., Uta, D., Takazawa, T., Hikitsuchi, T., Kawajiri, Y. & Nakayama, K., 2020, In: International Journal of Automation Technology. 14, 1, p. 117-127 11 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

4 被引用数 (Scopus)

Development of artificial skin using keratin film for evaluation of puncture performance of microneedle

Nishino, R., Aoyagi, S., Suzuki, M., Ueda, A., Okumura, Y., Takahashi, T., Hosomi, R., Fukunaga, K., Uta, D., Takazawa, T. & Fujii, T., 2020, In: Journal of Robotics and Mechatronics. 32, 2, p. 351-361 11 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

7 被引用数 (Scopus)

Differential effects of alpha 1-Adrenoceptor antagonists on the postsynaptic sensitivity: Using slice patch-clamp technique for inhibitory postsynaptic current in substantia gelatinosa neurons from lumbosacral spinal cord in rats

Uta, D., Hattori, T. & Yoshimura, M., 2020/06/01, In: International Neurourology Journal. 24, 2, p. 127-134 8 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

2 被引用数 (Scopus)

Effect of alpha 1-Adrnoceptor antagonists on postsynaptic sensitivity in substantia gelatinosa neurons from lumbosacral spinal cord in rats using slice patch-clamp technique for mEPSC

Uta, D., Hattori, T. & Yoshimura, M., 2020/06/01, In: International Neurourology Journal. 24, 2, p. 135-143 9 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

4 被引用数 (Scopus)

Excessive exercise induces cardiac arrhythmia in a young fibromyalgia mouse model

Nakata, T., Doi, A., Uta, D., Yoshimura, M. & Shin, M. C., 2020/09, In: PLoS ONE. 15, 9 September, e0239473.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

2 被引用数 (Scopus)

GRP receptor and AMPA receptor cooperatively regulate itch-responsive neurons in the spinal dorsal horn

Kiguchi, N., Uta, D., Ding, H., Uchida, H., Saika, F., Matsuzaki, S., Fukazawa, Y., Abe, M., Sakimura, K., Ko, M. C. & Kishioka, S., 2020/06/15, In: Neuropharmacology. 170, 108025.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

30 被引用数 (Scopus)

Inhibitory effect of amenamevir on acute herpetic pain and postherpetic neuralgia in mice infected with herpes simplex virus-1

Ueda, Y., Uta, D., Tanbo, S., Kawabata, A., Kanayama, S., Osaki, M., Nozawa, N., Matsumoto, T. & Andoh, T., 2020/04, In: Journal of Dermatological Science. 98, 1, p. 50-57 8 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

8 被引用数 (Scopus)

Neuronal hyperexcitability and astrocyte activation in spinal dorsal horn of a dermatitis mouse model with cutaneous hypersensitivity

Inami, Y., Uta, D. & Andoh, T., 2020/02/16, In: Neuroscience Letters. 720, 134784.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

4 被引用数 (Scopus)

2019

Animal models of chronic pain increase spontaneous glutamatergic transmission in adult rat spinal dorsal horn in vitro and in vivo

Uta, D., Kato, G., Doi, A., Andoh, T., Kume, T., Yoshimura, M. & Koga, K., 2019/04/30, In: Biochemical and Biophysical Research Communications. 512, 2, p. 352-359 8 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

22 被引用数 (Scopus)

Characterization on responsiveness of excitatory synaptic transmissions to α1-adrenoceptor blockers in substantia gelatinosa neurons isolated from lumbo-sacral level in rat spinal cords

Uta, D., Hattori, T. & Yoshimura, M., 2019, In: International Neurourology Journal. 23, 1, p. 13-21 9 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

5 被引用数 (Scopus)

Chronic pain models amplify transient receptor potential vanilloid 1 (TRPV1) receptor responses in adult rat spinal dorsal horn

Uta, D., Yoshimura, M. & Koga, K., 2019/12/01, In: Neuropharmacology. 160, 107753.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

14 被引用数 (Scopus)

Noradrenaline modulates mechanically evoked responses in the rat spinal dorsal horn: An in vivo patch-clamp study

Sonohata, M., Doi, A., Yasaka, T., Uta, D., Mawatari, M. & Yoshimura, M., 2019, In: Journal of Pain Research. 12, p. 1269-1278 10 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

3 被引用数 (Scopus)

Prophylactic Repetitive Treatment with the Herbal Medicine Kei-kyoh-zoh-soh-oh-shin-bu-toh Attenuates Oxaliplatin-Induced Mechanical Allodynia by Decreasing Spinal Astrocytes

Andoh, T., Fukutomi, D., Uta, D. & Kuraishi, Y., 2019, In: Evidence-based Complementary and Alternative Medicine. 2019, 4029694.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

6 被引用数 (Scopus)

β2-Microglobulin, interleukin-31, and arachidonic acid metabolites (leukotriene B₄ and thromboxane A₂) are involved in chronic renal failure-associated itch-associated responses in mice

Li, S., Andoh, T., Zhang, Q., Uta, D. & Kuraishi, Y., 2019/03/15, In: European Journal of Pharmacology. 847, p. 19-25 7 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

10 被引用数 (Scopus)

2018

Effects of high concentrations of naftopidil on dorsal root- evoked excitatory synaptic transmissions in substantia gelatinosa neurons in vitro

Uta, D., Hattori, T. & Yoshimura, M., 2018/12/01, In: International Neurourology Journal. 22, 4, p. 252-259 8 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

5 被引用数 (Scopus)

Effects of naftopidil in substantia gelatinosa neurons of the adult rat spinal dorsal horn.

寄稿の翻訳タイトル: Effects of naftopidil in substantia gelatinosa neurons of the adult rat spinal dorsal horn.Uta, D., Hattori, T., Kasahara, K. & Yoshimura, M., 2018, In: The Journal of Functional Diagnosis of the Spinal Cord. 39, 1, p. 7-13 7 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Involvement of thromboxane A₂ in interleukin-31-induced itch-associated response in mice

Andoh, T., Li, S. & Uta, D., 2018/04, In: Pharmacological Reports. 70, 2, p. 251-257 7 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

14 被引用数 (Scopus)

Peripheral and spinal mechanisms of nociceptive transmission in a rat model of fibromyalgia.

寄稿の翻訳タイトル: Peripheral and spinal mechanisms of nociceptive transmission in a rat model of fibromyalgia.Uta, D. & Taguchi, T., 2018, In: PAIN RESEARCH . 32, 4, p. 280-287 8 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Physiological significances TRP-ANO1 interaction.

寄稿の翻訳タイトル: Physiological significances TRP-ANO1 interaction.Takayama, Y., Shibasaki, K., Furue, H., Uta, D. & Tominaga, M., 2018, In: PAIN RESEARCH . 33, 1, p. 1-9 9 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Underlying mechanisms of acetaminophen in the spinal dorsal horn neurons

Ohashi, N., Uta, D. & Kohno, T., 2018, In: Japanese Journal of Anesthesiology. 67, p. S259-S267

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

線維筋痛症モデルラット脊髄後角細胞における侵害情報伝達のin vivoパッチクランプ解析

歌大介, 坪島功幸, 安東嗣修, 西条寿夫, 水村和枝 & 田口徹, 2018/06, In: PAIN RESEARCH . 33, 2, p. 135-135 1 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

2017

Acetaminophen metabolite n-acylphenolamine induces analgesia via transient receptor potential vanilloid 1 receptors expressed on the primary afferent terminals of c-fibers in the spinal dorsal horn

Ohashi, N., Uta, D., Sasaki, M., Ohashi, M., Kamiya, Y. & Kohno, T., 2017/08/01, In: Anesthesiology. 127, 2, p. 355-371 17 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

28 被引用数 (Scopus)

Actions of transient receptor potential ankyrin 1 (TRPA1) channel agonists on nociceptive synaptic transmission to spinal dorsal horn neurons in rat spinal cord: In vitro and in vivo patch-clamp analyses.

寄稿の翻訳タイトル: Actions of transient receptor potential ankyrin 1 (TRPA1) channel agonists on nociceptive synaptic transmission to spinal dorsal horn neurons in rat spinal cord: In vitro and in vivo patch-clamp analyses.Uta, D., Imoto, K. & Furue, H., 2017, In: PAIN RESEARCH . 32, 3, p. 179-190 12 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

歌 大介

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歌大介