Targeting Pancreatic Cancer with Novel Plumbagin Derivatives: Design, Synthesis, Molecular Mechanism, In Vitro and In Vivo Evaluation

Suresh Awale; Hayato Baba; Nguyen duy Phan; Min jo Kim; Juthamart Maneenet; Koichi Sawaki; Mitsuro Kanda; Tomoyuki Okumura; Tsutomu Fujii; Takuya Okada; Takahiro Maruyama; Takahiro Okada; Naoki Toyooka

doi:10.1021/acs.jmedchem.3c00394

Targeting Pancreatic Cancer with Novel Plumbagin Derivatives: Design, Synthesis, Molecular Mechanism, In Vitro and In Vivo Evaluation

Suresh Awale^*, Hayato Baba, Nguyen duy Phan, Min jo Kim, Juthamart Maneenet, Koichi Sawaki, Mitsuro Kanda, Tomoyuki Okumura, Tsutomu Fujii, Takuya Okada^*, Takahiro Maruyama, Takahiro Okada, Naoki Toyooka^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Original language	English
Pages (from-to)	8054-8065
Journal	Journal of Medicinal Chemistry
Volume	66
Issue number	12
DOIs	https://doi.org/10.1021/acs.jmedchem.3c00394
State	Published - 2023/06/22
Externally published	Yes

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Access to Document

10.1021/acs.jmedchem.3c00394

https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c00394

Cite this

Awale, S., Baba, H., Phan, N. D., Kim, M. J., Maneenet, J., Sawaki, K., Kanda, M., Okumura, T., Fujii, T., Okada, T., Maruyama, T., Okada, T., & Toyooka, N. (2023). Targeting Pancreatic Cancer with Novel Plumbagin Derivatives: Design, Synthesis, Molecular Mechanism, In Vitro and In Vivo Evaluation. Journal of Medicinal Chemistry, 66(12), 8054-8065. https://doi.org/10.1021/acs.jmedchem.3c00394

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title = "Targeting Pancreatic Cancer with Novel Plumbagin Derivatives: Design, Synthesis, Molecular Mechanism, In Vitro and In Vivo Evaluation",

author = "Suresh Awale and Hayato Baba and Phan, {Nguyen duy} and Kim, {Min jo} and Juthamart Maneenet and Koichi Sawaki and Mitsuro Kanda and Tomoyuki Okumura and Tsutomu Fujii and Takuya Okada and Takahiro Maruyama and Takahiro Okada and Naoki Toyooka",

year = "2023",

month = jun,

day = "22",

doi = "10.1021/acs.jmedchem.3c00394",

language = "英語",

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publisher = "American Chemical Society",

number = "12",

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Awale, S, Baba, H, Phan, ND, Kim, MJ, Maneenet, J, Sawaki, K, Kanda, M, Okumura, T , Fujii, T , Okada, T, Maruyama, T, Okada, T & Toyooka, N 2023, 'Targeting Pancreatic Cancer with Novel Plumbagin Derivatives: Design, Synthesis, Molecular Mechanism, In Vitro and In Vivo Evaluation', Journal of Medicinal Chemistry, vol. 66, no. 12, pp. 8054-8065. https://doi.org/10.1021/acs.jmedchem.3c00394

TY - JOUR

T1 - Targeting Pancreatic Cancer with Novel Plumbagin Derivatives: Design, Synthesis, Molecular Mechanism, In Vitro and In Vivo Evaluation

AU - Awale, Suresh

AU - Baba, Hayato

AU - Phan, Nguyen duy

AU - Kim, Min jo

AU - Maneenet, Juthamart

AU - Sawaki, Koichi

AU - Kanda, Mitsuro

AU - Okumura, Tomoyuki

AU - Fujii, Tsutomu

AU - Okada, Takuya

AU - Maruyama, Takahiro

AU - Okada, Takahiro

AU - Toyooka, Naoki

PY - 2023/6/22

Y1 - 2023/6/22

U2 - 10.1021/acs.jmedchem.3c00394

DO - 10.1021/acs.jmedchem.3c00394

M3 - 学術論文

C2 - 37257133

SN - 0022-2623

VL - 66

SP - 8054

EP - 8065

JO - Journal of Medicinal Chemistry

JF - Journal of Medicinal Chemistry

IS - 12

ER -