A new cycloartane-type triterpene and a new eicosanoic acid ester from fruits of Paullinia pinnata L.

Maurice D. Awouafack; Takuya Ito; Pierre Tane; Takeshi Kodama; Masami Tanaka; Yoshinori Asakawa; Hiroyuki Morita

doi:10.1016/j.phytol.2016.02.002

A new cycloartane-type triterpene and a new eicosanoic acid ester from fruits of Paullinia pinnata L.

Maurice D. Awouafack^*, Takuya Ito, Pierre Tane, Takeshi Kodama, Masami Tanaka, Yoshinori Asakawa, Hiroyuki Morita

^*Corresponding author for this work

Section of Natural Products & Drug Discovery, Division of Medicinal Resources, Institute of Natural Medicine

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

A phytochemical study of the MeOH-soluble portion from the CH₂Cl₂/MeOH extract of the fruits of Paullinia pinnata resulted in the isolation of a new triterpenoid, cyclopinnatol (1), and a new eicosanoic acid ester, paulliniester (2), together with five known compounds including cycloart-22(E)-ene-3β,25-diol (3), cycloartenol (4), β-sitosterol (5), betulonic acid (6) and oleanonic acid (7). The structures of the new compounds were elucidated by spectroscopic analyses (NMR and MS) and comparisons with published data. Cyclopinnatol (1) and the MeOH-soluble portion exhibited significant and weak antibacterial activities against Staphylococcus aureus, with MICs of 32 and 50 μg/mL, respectively.

Original language	English
Pages (from-to)	220-224
Number of pages	5
Journal	Phytochemistry Letters
Volume	15
DOIs	https://doi.org/10.1016/j.phytol.2016.02.002
State	Published - 2016/03/01

Keywords

Antibacterial activity
Cyclopinnatol
Paullinia pinnata
Paulliniester
Sapindaceae

ASJC Scopus subject areas

Biotechnology
Biochemistry
Agronomy and Crop Science
Plant Science

Access to Document

10.1016/j.phytol.2016.02.002

Cite this

@article{171b3ec11d514fae86b61a2d1f6ada26,

title = "A new cycloartane-type triterpene and a new eicosanoic acid ester from fruits of Paullinia pinnata L.",

abstract = "A phytochemical study of the MeOH-soluble portion from the CH2Cl2/MeOH extract of the fruits of Paullinia pinnata resulted in the isolation of a new triterpenoid, cyclopinnatol (1), and a new eicosanoic acid ester, paulliniester (2), together with five known compounds including cycloart-22(E)-ene-3β,25-diol (3), cycloartenol (4), β-sitosterol (5), betulonic acid (6) and oleanonic acid (7). The structures of the new compounds were elucidated by spectroscopic analyses (NMR and MS) and comparisons with published data. Cyclopinnatol (1) and the MeOH-soluble portion exhibited significant and weak antibacterial activities against Staphylococcus aureus, with MICs of 32 and 50 μg/mL, respectively.",

keywords = "Antibacterial activity, Cyclopinnatol, Paullinia pinnata, Paulliniester, Sapindaceae",

author = "Awouafack, {Maurice D.} and Takuya Ito and Pierre Tane and Takeshi Kodama and Masami Tanaka and Yoshinori Asakawa and Hiroyuki Morita",

year = "2016",

month = mar,

day = "1",

doi = "10.1016/j.phytol.2016.02.002",

language = "英語",

volume = "15",

pages = "220--224",

journal = "Phytochemistry Letters",

issn = "1874-3900",

publisher = "Elsevier Ltd.",

}

TY - JOUR

T1 - A new cycloartane-type triterpene and a new eicosanoic acid ester from fruits of Paullinia pinnata L.

AU - Awouafack, Maurice D.

AU - Ito, Takuya

AU - Tane, Pierre

AU - Kodama, Takeshi

AU - Tanaka, Masami

AU - Asakawa, Yoshinori

AU - Morita, Hiroyuki

PY - 2016/3/1

Y1 - 2016/3/1

N2 - A phytochemical study of the MeOH-soluble portion from the CH2Cl2/MeOH extract of the fruits of Paullinia pinnata resulted in the isolation of a new triterpenoid, cyclopinnatol (1), and a new eicosanoic acid ester, paulliniester (2), together with five known compounds including cycloart-22(E)-ene-3β,25-diol (3), cycloartenol (4), β-sitosterol (5), betulonic acid (6) and oleanonic acid (7). The structures of the new compounds were elucidated by spectroscopic analyses (NMR and MS) and comparisons with published data. Cyclopinnatol (1) and the MeOH-soluble portion exhibited significant and weak antibacterial activities against Staphylococcus aureus, with MICs of 32 and 50 μg/mL, respectively.

AB - A phytochemical study of the MeOH-soluble portion from the CH2Cl2/MeOH extract of the fruits of Paullinia pinnata resulted in the isolation of a new triterpenoid, cyclopinnatol (1), and a new eicosanoic acid ester, paulliniester (2), together with five known compounds including cycloart-22(E)-ene-3β,25-diol (3), cycloartenol (4), β-sitosterol (5), betulonic acid (6) and oleanonic acid (7). The structures of the new compounds were elucidated by spectroscopic analyses (NMR and MS) and comparisons with published data. Cyclopinnatol (1) and the MeOH-soluble portion exhibited significant and weak antibacterial activities against Staphylococcus aureus, with MICs of 32 and 50 μg/mL, respectively.

KW - Antibacterial activity

KW - Cyclopinnatol

KW - Paullinia pinnata

KW - Paulliniester

KW - Sapindaceae

UR - http://www.scopus.com/inward/record.url?scp=84957967797&partnerID=8YFLogxK

U2 - 10.1016/j.phytol.2016.02.002

DO - 10.1016/j.phytol.2016.02.002

M3 - 学術論文

AN - SCOPUS:84957967797

SN - 1874-3900

VL - 15

SP - 220

EP - 224

JO - Phytochemistry Letters

JF - Phytochemistry Letters

ER -

A new cycloartane-type triterpene and a new eicosanoic acid ester from fruits of Paullinia pinnata L.

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Fingerprint

Cite this