TY - JOUR
T1 - A new cycloartane-type triterpene and a new eicosanoic acid ester from fruits of Paullinia pinnata L.
AU - Awouafack, Maurice D.
AU - Ito, Takuya
AU - Tane, Pierre
AU - Kodama, Takeshi
AU - Tanaka, Masami
AU - Asakawa, Yoshinori
AU - Morita, Hiroyuki
N1 - Publisher Copyright:
© 2016 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
PY - 2016/3/1
Y1 - 2016/3/1
N2 - A phytochemical study of the MeOH-soluble portion from the CH2Cl2/MeOH extract of the fruits of Paullinia pinnata resulted in the isolation of a new triterpenoid, cyclopinnatol (1), and a new eicosanoic acid ester, paulliniester (2), together with five known compounds including cycloart-22(E)-ene-3β,25-diol (3), cycloartenol (4), β-sitosterol (5), betulonic acid (6) and oleanonic acid (7). The structures of the new compounds were elucidated by spectroscopic analyses (NMR and MS) and comparisons with published data. Cyclopinnatol (1) and the MeOH-soluble portion exhibited significant and weak antibacterial activities against Staphylococcus aureus, with MICs of 32 and 50 μg/mL, respectively.
AB - A phytochemical study of the MeOH-soluble portion from the CH2Cl2/MeOH extract of the fruits of Paullinia pinnata resulted in the isolation of a new triterpenoid, cyclopinnatol (1), and a new eicosanoic acid ester, paulliniester (2), together with five known compounds including cycloart-22(E)-ene-3β,25-diol (3), cycloartenol (4), β-sitosterol (5), betulonic acid (6) and oleanonic acid (7). The structures of the new compounds were elucidated by spectroscopic analyses (NMR and MS) and comparisons with published data. Cyclopinnatol (1) and the MeOH-soluble portion exhibited significant and weak antibacterial activities against Staphylococcus aureus, with MICs of 32 and 50 μg/mL, respectively.
KW - Antibacterial activity
KW - Cyclopinnatol
KW - Paullinia pinnata
KW - Paulliniester
KW - Sapindaceae
UR - http://www.scopus.com/inward/record.url?scp=84957967797&partnerID=8YFLogxK
U2 - 10.1016/j.phytol.2016.02.002
DO - 10.1016/j.phytol.2016.02.002
M3 - 学術論文
AN - SCOPUS:84957967797
SN - 1874-3900
VL - 15
SP - 220
EP - 224
JO - Phytochemistry Letters
JF - Phytochemistry Letters
ER -