A new alkenylmethylresorcinol from the fruits of Ardisia kivuensis

Yves M.M. Nguekeu; Blanche L. Ndontsa; Roukayatou Mbouangouere; Maurice D. Awouafack; Takuya Ito; Pierre Tane; Hiroyuki Morita

doi:10.1177/1934578x1601100527

A new alkenylmethylresorcinol from the fruits of Ardisia kivuensis

Yves M.M. Nguekeu, Blanche L. Ndontsa, Roukayatou Mbouangouere, Maurice D. Awouafack, Takuya Ito, Pierre Tane, Hiroyuki Morita

Section of Natural Products & Drug Discovery, Division of Medicinal Resources, Institute of Natural Medicine

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

The phytochemical study of the MeOH extract from the fruits of Ardisia kivuensis was carried out using repeated silica gel column chromatography followed by Sephadex LH-20 to afford a new alkenylmethylresorcinol, ardisinol III (1) along with three known compounds, oleanolic acid, β-sitosterol and pentacosanoic acid. The structure of 1 was elucidated using spectroscopic analysis (NMR and MS), and comparison with published data. Compound 1 had weak antioxidant activity (IC50 109.8 μg/mL) while other compounds were not active as compared to L-ascorbic acid (IC50 3.9 μg/mL).

Original language	English
Pages (from-to)	661-662
Number of pages	2
Journal	Natural Product Communications
Volume	11
Issue number	5
DOIs	https://doi.org/10.1177/1934578x1601100527
State	Published - 2016/05

Keywords

Alkenylmethylresorcinol
Antioxidant
Ardisia kivuensis
Ardisinol III
Myrsinaceae

ASJC Scopus subject areas

Pharmacology
Plant Science
Drug Discovery
Complementary and alternative medicine

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10.1177/1934578x1601100527

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title = "A new alkenylmethylresorcinol from the fruits of Ardisia kivuensis",

abstract = "The phytochemical study of the MeOH extract from the fruits of Ardisia kivuensis was carried out using repeated silica gel column chromatography followed by Sephadex LH-20 to afford a new alkenylmethylresorcinol, ardisinol III (1) along with three known compounds, oleanolic acid, β-sitosterol and pentacosanoic acid. The structure of 1 was elucidated using spectroscopic analysis (NMR and MS), and comparison with published data. Compound 1 had weak antioxidant activity (IC50 109.8 μg/mL) while other compounds were not active as compared to L-ascorbic acid (IC50 3.9 μg/mL).",

keywords = "Alkenylmethylresorcinol, Antioxidant, Ardisia kivuensis, Ardisinol III, Myrsinaceae",

author = "Nguekeu, {Yves M.M.} and Ndontsa, {Blanche L.} and Roukayatou Mbouangouere and Awouafack, {Maurice D.} and Takuya Ito and Pierre Tane and Hiroyuki Morita",

year = "2016",

month = may,

doi = "10.1177/1934578x1601100527",

language = "英語",

volume = "11",

pages = "661--662",

journal = "Natural Product Communications",

issn = "1934-578X",

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T1 - A new alkenylmethylresorcinol from the fruits of Ardisia kivuensis

AU - Nguekeu, Yves M.M.

AU - Ndontsa, Blanche L.

AU - Mbouangouere, Roukayatou

AU - Awouafack, Maurice D.

AU - Ito, Takuya

AU - Tane, Pierre

AU - Morita, Hiroyuki

PY - 2016/5

Y1 - 2016/5

N2 - The phytochemical study of the MeOH extract from the fruits of Ardisia kivuensis was carried out using repeated silica gel column chromatography followed by Sephadex LH-20 to afford a new alkenylmethylresorcinol, ardisinol III (1) along with three known compounds, oleanolic acid, β-sitosterol and pentacosanoic acid. The structure of 1 was elucidated using spectroscopic analysis (NMR and MS), and comparison with published data. Compound 1 had weak antioxidant activity (IC50 109.8 μg/mL) while other compounds were not active as compared to L-ascorbic acid (IC50 3.9 μg/mL).

AB - The phytochemical study of the MeOH extract from the fruits of Ardisia kivuensis was carried out using repeated silica gel column chromatography followed by Sephadex LH-20 to afford a new alkenylmethylresorcinol, ardisinol III (1) along with three known compounds, oleanolic acid, β-sitosterol and pentacosanoic acid. The structure of 1 was elucidated using spectroscopic analysis (NMR and MS), and comparison with published data. Compound 1 had weak antioxidant activity (IC50 109.8 μg/mL) while other compounds were not active as compared to L-ascorbic acid (IC50 3.9 μg/mL).

KW - Alkenylmethylresorcinol

KW - Antioxidant

KW - Ardisia kivuensis

KW - Ardisinol III

KW - Myrsinaceae

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U2 - 10.1177/1934578x1601100527

DO - 10.1177/1934578x1601100527

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SP - 661

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JO - Natural Product Communications

JF - Natural Product Communications

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ER -

A new alkenylmethylresorcinol from the fruits of Ardisia kivuensis

Abstract

Keywords

ASJC Scopus subject areas

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