A new alkenylmethylresorcinol from the fruits of Ardisia kivuensis

Yves M.M. Nguekeu; Blanche L. Ndontsa; Roukayatou Mbouangouere; Maurice D. Awouafack; Takuya Ito; Pierre Tane; Hiroyuki Morita

doi:10.1177/1934578x1601100527

A new alkenylmethylresorcinol from the fruits of Ardisia kivuensis

Yves M.M. Nguekeu, Blanche L. Ndontsa, Roukayatou Mbouangouere, Maurice D. Awouafack, Takuya Ito, Pierre Tane, Hiroyuki Morita

和漢医薬学総合研究所研究開発部門資源開発分野（天然物創薬学領域）

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

7 被引用数 (Scopus)

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The phytochemical study of the MeOH extract from the fruits of Ardisia kivuensis was carried out using repeated silica gel column chromatography followed by Sephadex LH-20 to afford a new alkenylmethylresorcinol, ardisinol III (1) along with three known compounds, oleanolic acid, β-sitosterol and pentacosanoic acid. The structure of 1 was elucidated using spectroscopic analysis (NMR and MS), and comparison with published data. Compound 1 had weak antioxidant activity (IC50 109.8 μg/mL) while other compounds were not active as compared to L-ascorbic acid (IC50 3.9 μg/mL).

本文言語	英語
ページ（範囲）	661-662
ページ数	2
ジャーナル	Natural Product Communications
巻	11
号	5
DOI	https://doi.org/10.1177/1934578x1601100527
出版ステータス	出版済み - 2016/05

ASJC Scopus 主題領域

薬理学
植物科学
創薬
補完代替医療

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10.1177/1934578x1601100527

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title = "A new alkenylmethylresorcinol from the fruits of Ardisia kivuensis",

abstract = "The phytochemical study of the MeOH extract from the fruits of Ardisia kivuensis was carried out using repeated silica gel column chromatography followed by Sephadex LH-20 to afford a new alkenylmethylresorcinol, ardisinol III (1) along with three known compounds, oleanolic acid, β-sitosterol and pentacosanoic acid. The structure of 1 was elucidated using spectroscopic analysis (NMR and MS), and comparison with published data. Compound 1 had weak antioxidant activity (IC50 109.8 μg/mL) while other compounds were not active as compared to L-ascorbic acid (IC50 3.9 μg/mL).",

keywords = "Alkenylmethylresorcinol, Antioxidant, Ardisia kivuensis, Ardisinol III, Myrsinaceae",

author = "Nguekeu, {Yves M.M.} and Ndontsa, {Blanche L.} and Roukayatou Mbouangouere and Awouafack, {Maurice D.} and Takuya Ito and Pierre Tane and Hiroyuki Morita",

year = "2016",

month = may,

doi = "10.1177/1934578x1601100527",

language = "英語",

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AU - Nguekeu, Yves M.M.

AU - Ndontsa, Blanche L.

AU - Mbouangouere, Roukayatou

AU - Awouafack, Maurice D.

AU - Ito, Takuya

AU - Tane, Pierre

AU - Morita, Hiroyuki

PY - 2016/5

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N2 - The phytochemical study of the MeOH extract from the fruits of Ardisia kivuensis was carried out using repeated silica gel column chromatography followed by Sephadex LH-20 to afford a new alkenylmethylresorcinol, ardisinol III (1) along with three known compounds, oleanolic acid, β-sitosterol and pentacosanoic acid. The structure of 1 was elucidated using spectroscopic analysis (NMR and MS), and comparison with published data. Compound 1 had weak antioxidant activity (IC50 109.8 μg/mL) while other compounds were not active as compared to L-ascorbic acid (IC50 3.9 μg/mL).

AB - The phytochemical study of the MeOH extract from the fruits of Ardisia kivuensis was carried out using repeated silica gel column chromatography followed by Sephadex LH-20 to afford a new alkenylmethylresorcinol, ardisinol III (1) along with three known compounds, oleanolic acid, β-sitosterol and pentacosanoic acid. The structure of 1 was elucidated using spectroscopic analysis (NMR and MS), and comparison with published data. Compound 1 had weak antioxidant activity (IC50 109.8 μg/mL) while other compounds were not active as compared to L-ascorbic acid (IC50 3.9 μg/mL).

KW - Alkenylmethylresorcinol

KW - Antioxidant

KW - Ardisia kivuensis

KW - Ardisinol III

KW - Myrsinaceae

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DO - 10.1177/1934578x1601100527

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SN - 1934-578X

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A new alkenylmethylresorcinol from the fruits of Ardisia kivuensis

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