宿主免疫細胞から攻撃されアポトーシスに陥った細胞を組織学的に同定する方法の開発

Research output

Research output per year 2006 2007 2008 2008

• 21 Presentation
• 17 Article
• 3 Review article
• 2 Book

Research output per year

Research output per year

Search results

• 2008

  Autophagy plays roles inn the invasion of extravillous trophoblast into the maternal side inn severe environments.

  M., T., A., N. & S., S., 2008.

  Research output: Contribution to conference › Presentation

• Blocking on the CXCR4/mTOR signalling pathway induces the anti-metastatic properties and autophagic cell death in peritoneal disseminated gastric cancer cells

  Hashimoto, I., Koizumi, K., Tatematsu, M., Minami, T., Cho, S., Takeno, N., Nakashima, A., Sakurai, H., Saito, S., Tsukada, K. & Saiki, I., 2008/05, In: European Journal of Cancer. 44, 7, p. 1022-1029 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Gastric Cancer 100%
  • Gastric Cancer Cells 100%
  • C-X-C Chemokine Receptor Type 4 (CXCR4) 100%
  • Peritoneal Carcinomatosis 100%
  • Mammalian Target of Rapamycin Signaling Pathway 100%
  123 Scopus citations

• Characterization of natural killer cells in nonobese diabetic/severely compromised immunodeficient mice during pregnancy.

  Y., L., Y., Z., S., S., Y., C., W., S., J., D. & S., Z., 2008, In: Fertility and Sterility.

  Research output: Contribution to journal › Article › peer-review

• Decidual Natural Killr cell derived granulysin induces apoptosis of extravillous trophoblast in miscarriage

  A., N., A., S., S., M., M., I., M., T. & S., S., 2008.

  Research output: Contribution to conference › Presentation

• Granulysin produced by uterine natural killer cells induces apoptosis of extravillous trophoblasts in spontaneous abortion

  Nakashima, A., Shiozaki, A., Myojo, S., Ito, M., Tatematsu, M., Sakai, M., Takamori, Y., Ogawa, K., Nagata, K. & Saito, S., 2008/09, In: American Journal of Pathology. 173, 3, p. 653-664 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Induced Apoptosis 100%
  • Extravillous Trophoblast 100%
  • Spontaneous Preterm Birth (sPTB) 100%
  • Granulysin 100%
  • Uterine Natural Killer Cells 100%
  84 Scopus citations

• I 病態と疾患 産科救急 流産・絨毛性疾患

  長谷川徹 & 齋藤 滋, 2008, In: 救急医学 32. p. 995-999

  Research output: Contribution to journal › Article › peer-review

• "Preeclampsia" The role of immune system in pre-eclampsia.

  S., S., 2008.

  Research output: Contribution to conference › Presentation

• Th1/Th2バランスからみた妊娠高血圧腎症の臨床症状

  塩崎有宏, 伊藤実香, 米田徳子, 立松美樹子, 明星須晴, 米田 哲 & 齋藤 滋, 2008.

  Research output: Contribution to conference › Presentation

• TH1/TH2比正常型PEの臨床症状。

  塩崎有宏, 稲田貢三子, 伊藤実香, 伊奈志帆美, 明星須晴, 米田 哲 & 齋藤 滋, 2008.

  Research output: Contribution to conference › Presentation

• The balance between cytotxic NK cells and regulatory NK cells in human pregnancy.

  S., S., A., N., S., M.-H. & A., S., 2008, In: J Reprod Immunol 77. p. 14-22

  Research output: Contribution to journal › Article › peer-review

• TSLP-induced placental DC activation and IL-10+ NK cell expansion : Comparative study based on BALB/cx C57BL/6 and NOD/SCID X C57 BL/6 pregnant models.

  Y., L., Y., Z., W., S., Y., C., J., S., J., D., S., Z. & S., S., 2008, In: Clin Immunol 126. p. 104-117

  Research output: Contribution to journal › Article › peer-review

• オートファジーによる低栄養、低酸素下での絨毛外栄養細胞浸潤能の亢進

  立松美樹子, 中島彰俊, 齋藤 滋 & 二階堂敏雄, 2008.

  Research output: Contribution to conference › Presentation

• シンポジウム「オートファジーの絨毛外栄養細胞における新たな調節機構」

  立松美樹子, 中島彰俊 & 齋藤 滋, 2008.

  Research output: Contribution to conference › Presentation

• 不育症の原因と治療

  齋藤滋, 2008, In: 日本医師会雑誌 137. p. 39-43

  Research output: Contribution to journal › Article › peer-review

• 周産期免疫 : シンポジウム「常態と病態 2 妊娠高血圧症候群」

  塩崎有宏, 米田 哲 & 齋藤 滋, 2008.

  Research output: Contribution to conference › Presentation

• 妊娠高血圧症候群の発症と免疫

  齋藤滋, 2008, In: 臨床免疫・アレルギー科 50(1). p. 82-89

  Research output: Contribution to journal › Article › peer-review

• 流産症例において、Granulysin陽性NK細胞はExtravillous trophoblast (EVT)をアポトーシスに陥らせる

  中島彰俊, 塩崎有宏, 伊藤実香, 立松美樹子, 明星須晴 & 齋藤 滋, 2008.

  Research output: Contribution to conference › Presentation

• 病態生理を解く免疫と妊娠高血圧症候群

  塩崎有宏 & 齋藤滋, 2008, In: 産婦人科の実際 57(1). p. 23-30

  Research output: Contribution to journal › Article › peer-review

• 第3章臓器特異的な樹状細胞4.生殖器における樹状細胞サブセット機能

  島友子 & 齋藤滋, 2008, In: 実験医学 増刊.. p. 140-145

  Research output: Contribution to journal › Article › peer-review

• 脱落膜NK細胞由来Granulysinは絨毛外トロホブラストにアポトーシスを誘導し、流産誘導に関与する

  中島彰俊, 塩崎有宏, 明星須晴, 伊藤実香, 立松美樹子 & 齋藤 滋, 2008.

  Research output: Contribution to conference › Presentation
• 2007

  Advanced malignant solitary fibrous tumor in pelvis responding to radiation therapy

  Kawamura, S., Nakamura, T., Oya, T., Ishizawa, S., Sakai, Y., Tanaka, T., Saito, S. & Fukuoka, J., 2007/04, In: Pathology International. 57, 4, p. 213-218 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Radiation Therapy 100%
  • Solitary Fibrous Tumor 100%
  • Pelvis 100%
  • Malignant Solitary Fibrous Tumor 100%
  • Tumor 50%
  53 Scopus citations

• Autophagy, bulk degradation system, promotes extravillous trophoblast invasion in low nutrient, hypoxia or hypoglycemic condition (相馬賞)

  A, N., M, T. & S., S., 2007.

  Research output: Contribution to conference › Presentation

• Decidual natural killer cell derived granulysin induces apoptosis of extravillous trophoblast in miscarriage

  A, N., A, S., S, M., M, I., M, T. & S, S., 2007.

  Research output: Contribution to conference › Presentation

• Epression of indoleamine 2, 3-dioxygenase and the recruitment of Foxp3-expressing regulatory T cells in the development and progre-ssion of uterine cervical cancer

  T, N., T, S., A, S., T, H., A, N., O, T. & S, S., 2007, In: Cancer Science 98. p. 874-881

  Research output: Contribution to journal › Article › peer-review

• Expression of autophagy in Extravillous trophoblast(EVT) on early prenancy

  M, T., A, N. & S, S., 2007.

  Research output: Contribution to conference › Presentation

• Local regulation of uterine lymphocytes in human

  S, S., 2007.

  Research output: Contribution to conference › Presentation

• Regulatory T cells and regulatory natural killer (NK) cells play important roles in feto-maternal tolerance

  Saito, S., Shiozaki, A., Sasaki, Y., Nakashima, A., Shima, T. & Ito, M., 2007/06, In: Seminars in Immunopathology. 29, 2, p. 115-122 8 p.

  Research output: Contribution to journal › Review article › peer-review

  • Regulatory T Cells 100%
  • Natural Killer Cells 100%
  • Fetal Tolerance 100%
  • T Regulatory 100%
  • Natural Killer Cell 100%
  130 Scopus citations

• Regulatory T cells and regulatory NK cells in normal pregnancy and spontaneous abortion cases

  S, S., 2007.

  Research output: Contribution to conference › Presentation

• The balance between cytotoxic NK cells and regulatory NK cells during prenancy

  A, N., 2007.

  Research output: Contribution to conference › Presentation

• Tolerance signaling molecules and pregnancy: IDO, galectins, and the renaissance of regulatory T cells

  Terness, P., Kallikourdis, M., Betz, A. G., Rabinovich, G. A., Saito, S. & Clark, D. A., 2007/09, In: American Journal of Reproductive Immunology. 58, 3, p. 238-254 17 p.

  Research output: Contribution to journal › Review article › peer-review

  • Regulatory T Cells 100%
  • Signaling Molecules 100%
  • Galectin-1 (Gal-1) 100%
  • Indoleamine 2,3-dioxygenase 1 (IDO1) 100%
  • Renaissance 100%
  99 Scopus citations

• What is the role of regulatory T cells in the success of implantation and early pregnancy?

  Saito, S., Shima, T., Nakashima, A., Shiozaki, A., Ito, M. & Sasaki, Y., 2007/10, In: Journal of Assisted Reproduction and Genetics. 24, 9, p. 379-386 8 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Regulatory T Cells 100%
  • Early Pregnancy 100%
  • Indoleamine 2,3-dioxygenase 1 (IDO1) 100%
  • Regulatory T Cell 100%
  • First Trimester Pregnancy 100%
  49 Scopus citations

• ヒト妊娠初期における胎盤の絨毛外栄養細胞とオートファジーとの関連

  立松 美樹子, 中島 彰俊 & 齋藤 滋, 2007.

  Research output: Contribution to conference › Presentation

• マウスallogenic妊娠において制御性T細胞は、初期では必要だが中期、後期では必要としない

  伊藤 実香, 佐々木 泰, 中島 彰俊, 島 友子 & 齋藤 滋, 2007.

  Research output: Contribution to conference › Presentation

• 妊娠初期の絨毛外栄養細胞(extravillous trophoblast:EVT)とAutophagyとの関連

  立松 美樹子, 中島 彰俊, 吉田 淑子, 二階堂 敏雄, 吉森 保 & 齋藤 滋, 2007.

  Research output: Contribution to conference › Presentation

• 妊娠高血圧症候群と免疫・妊娠高血圧症候群におけるT細胞およびNK細胞の役割

  中島 彰俊, 2007.

  Research output: Contribution to conference › Presentation

• 子宮内膜症患者末梢血および腹水中の制御細胞T細胞に関する検討

  伊藤 実香, 日高 隆雄, 若杉 聡美, 柳楽 清文, 中島 彰俊 & 齋藤 滋, 2007.

  Research output: Contribution to conference › Presentation
• 2006

  Activated NK cells in spontaneous abortion cases induce apoptosis on extravillous trophobalst in a granulysin dependent manner.

  A., N. & al., E., 2006, In: Am J Reprod Immunol 55. p. 397-398

  Research output: Contribution to journal › Article › peer-review

• Immature natural killer cells suppress dendritic cell functions during the development of leukemia in a mouse model.

  K., E. & al., E., 2006, In: Journal of Immunology. p. 4113-4124

  Research output: Contribution to journal › Article › peer-review

• Immunology of pregnancy

  S., S. & al., E., 2006, Landes Bioscience/Eurekah.com and Springer Science+Business Media, Inc. 323 p.

  Research output: Book/Report › Book › peer-review

• Liver-targeted and peripheral blood alterations of regulatory T cells in primary biliary cirrhosis

  Lan, R. Y., Cheng, C., Lian, Z. X., Tsuneyama, K., Yang, G. X., Moritoki, Y., Chuang, Y. H., Nakamura, T., Saito, S., Shimoda, S., Tanaka, A., Bowlus, C. L., Takano, Y., Ansari, A. A., Coppel, R. L. & Gershwin, M. E., 2006/04, In: Hepatology. 43, 4, p. 729-737 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Regulatory T Cells 100%
  • Peripheral Blood 100%
  • Primary Biliary Cirrhosis 100%
  • Blood Changes 100%
  • Liver Targeting 100%
  284 Scopus citations

• Plasma granulysin concentrations and preeclampsia risk

  Qiu, C., Saito, S., Sakai, M., Ogawa, K., Nagata, K. & Williams, M. A., 2006/10, In: Clinical Biochemistry. 39, 10, p. 1016-1021 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Granulysin 100%
  • Concentration Risk 100%
  • Preeclampsia Risk 100%
  • Blood Plasma 100%
  • Pre-Eclampsia 100%
  11 Scopus citations

• Survival of parovirus B19-infected cells by cellular autophagy.

  A., N. & al., E., 2006, In: Virology 349. p. 254-263

  Research output: Contribution to journal › Article › peer-review

• 臨床エビデンス産科学 第2版 執筆内容「母児免疫応答 -産科学の基礎と展開-」

  斎藤 滋, 2006, メジカルビュー社.

  Research output: Book/Report › Book › peer-review