Projects per year
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
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Dive into the research topics where Hospital Pharmacy is active. These topic labels come from the works of this organization's members. Together they form a unique fingerprint.
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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変異酵素の立体構造を化学的に操作できるシャペロン化合物の合理的設計と機能解析
Kato, A. (Principal Investigator), 達石井 (Co-Investigator(Kenkyū-buntansha)), 泉中込 (Co-Investigator(Kenkyū-buntansha)) & 良浩名取 (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2024/04/01 → 2027/03/31
Project: Research Project
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Analyses of essential interactions of iminosugars with the Hex A active site and evaluation of their pharmacological chaperone effects for Tay-Sachs disease
Kato, A. (PI)
2017/04/01 → 2020/03/31
Project: Research
Research output
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Enantiomeric C-6 fluorinated swainsonine derivatives as highly selective and potent inhibitors of α-mannosidase and α-L-rhamnosidase: Design, synthesis and structure-activity relationship study
Gao, F.-T., Zhang, M., Shimadate, Y., Kato, A., Li, Y.-X., Jia, Y.-M. & Yu, C.-Y., 2025/01/01, In: European Journal of Medicinal Chemistry. 282, p. 117031Research output: Contribution to journal › Article › peer-review
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GAA活性中心近傍に存在する疎水性ポケットの発見とポンペ病に対する選択的シャペロン化合物の創製
加藤 敦, 中込 泉, 喜瀬 真妃, 吉村 洸亮, 岡田 卓哉, 豊岡 尚樹 & 田中 信忠, 2024.Research output: Contribution to conference › Presentation
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Synthesis of 8-epi-L-swainsonine, related C6 alkylated derivatives and their α-L-rhamnosidase inhibition
Shimadate, Y., Oshima, S., Kasamatsu, N., Yamamoto, S., Taguchi, A., Nash, R. J., Fleet, G. W. J., Okada, T., Toyooka, N. & Kato, A., 2024/03/01, In: Tetrahedron Letters. p. 155008Research output: Contribution to journal › Article › peer-review
1 Scopus citations
Datasets
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CCDC 1413357: Experimental Crystal Structure Determination
Soengas, R. G. (Creator), Silva, V. L. M. (Creator), Ide, D. (Creator), Kato, A. (Creator), Cardoso, S. M. (Creator), Almeida Paz, F. A. (Contributor) & Silva, A. M. S. (Creator), Cambridge Crystallographic Data Centre, 2016
DOI: 10.5517/ccdc.csd.cc1jfq5v, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc1jfq5v&sid=DataCite
Dataset
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CCDC 2234788: Experimental Crystal Structure Determination
Gao, F.-T. (Contributor), Zhang, M. (Contributor), Shimadate, Y. (Contributor), Kato, A. (Contributor), Li, Y.-X. (Contributor), Jia, Y.-M. (Contributor) & Yu, C.-Y. (Contributor), Cambridge Crystallographic Data Centre, 2024
DOI: 10.5517/ccdc.csd.cc2f0gyw, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc2f0gyw&sid=DataCite
Dataset
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CCDC 970784: Experimental Crystal Structure Determination
Desire, J. (Creator), Mondon, M. (Creator), Fontelle, N. (Creator), Nakagawa, S. (Creator), Hirokami, Y. (Creator), Adachi, I. (Creator), Iwaki, R. (Creator), Fleet, G. W. J. (Creator), Alonzi, D. S. (Creator), Twigg, G. (Creator), Butters, T. D. (Creator), Bertrand, J. (Creator), Cendret, V. (Creator), Becq, F. (Creator), Norez, C. (Creator), Marrot, J. (Creator), Kato, A. (Creator) & Bleriot, Y. (Creator), Cambridge Crystallographic Data Centre, 2014
DOI: 10.5517/cc11l5mf, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc11l5mf&sid=DataCite
Dataset
Prizes
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Tetrahedron: Asymmetry: Top-25 Most Cited Articles 2010-2011 Award
Kato, A. (Recipient), 2012/01
Prize
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Tetrahedron: Asymmetry: Top-25 Most Cited Articles 2010-2011 Award
Kato, A. (Recipient), 2012/01
Prize
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植物由来化合物の機能性化粧品素材への応用：Ginnalin B の生物活性に関する研究
Shinzawa, K. (Speaker)
2022/10/16Activity: Talk or presentation › Oral presentation
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5-C-分岐型デオキシノジリマイシンを基盤としたGAA高親和性シャペロンのデザイン研究
Shinzawa, K. (Speaker)
2022/10/01Activity: Talk or presentation › Oral presentation
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Casuarine誘導体の各種グリコシダーゼに対する阻害活性と構造活性相関
Shinzawa, K. (Speaker)
2022/03/28Activity: Talk or presentation › Oral presentation