Projects per year
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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Analyses of essential interactions of iminosugars with the Hex A active site and evaluation of their pharmacological chaperone effects for Tay-Sachs disease
Kato, A. (PI)
2017/04/01 → 2020/03/31
Project: Research
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Enantiomeric C-6 fluorinated swainsonine derivatives as highly selective and potent inhibitors of α-mannosidase and α-L-rhamnosidase: Design, synthesis and structure-activity relationship study
Gao, F.-T., Zhang, M., Shimadate, Y., Kato, A., Li, Y.-X., Jia, Y.-M. & Yu, C.-Y., 2025/01/01, In: European Journal of Medicinal Chemistry. 282, p. 117031Research output: Contribution to journal › Article › peer-review
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Synthesis of 8-epi-L-swainsonine, related C6 alkylated derivatives and their α-L-rhamnosidase inhibition
Shimadate, Y., Oshima, S., Kasamatsu, N., Yamamoto, S., Taguchi, A., Nash, R. J., Fleet, G. W. J., Okada, T., Toyooka, N. & Kato, A., 2024/03/01, In: Tetrahedron Letters. p. 155008Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Distinctive accumulation of globotriaosylceramide and globotriaosylsphingosine in a mouse model of classic Fabry disease
Taguchi, A., Ishii, S., Mikame, M. & Maruyama, H., 2023/03, In: Molecular Genetics and Metabolism Reports. 34, 100952.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations
Datasets
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CCDC 1857705: Experimental Crystal Structure Determination
Carroll, A. W. (Creator), Willis, A. C. (Creator), Hoshino, M. (Creator), Kato, A. (Creator) & Pyne, S. G. (Creator), Cambridge Crystallographic Data Centre, 2019
DOI: 10.5517/ccdc.csd.cc20c2zg, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc20c2zg&sid=DataCite
Dataset
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Structure of acid-beta-glucosidase in complex with an aromatic pyrrolidine iminosugar inhibitor
Martínez-Bailén, M. (Contributor), Carmona, A. T. (Contributor), Patterson-Orazem, A. C. (Contributor), Lieberman, R. L. (Contributor), Ide, D. (Contributor), Kubo, M. (Contributor), Kato, A. (Contributor), Robina, I. (Contributor) & Moreno-Vargas, A. J. (Contributor), Protein Data Bank (PDB), 2019/06/19
DOI: 10.2210/pdb6MOZ/pdb, https://www.wwpdb.org/pdb?id=pdb_00006moz
Dataset
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CCDC 1843347: Experimental Crystal Structure Determination
Knudsen, I. M. B. (Creator), Hedberg, C. (Creator), Ladefoged, L. K. (Creator), Ide, D. (Creator), Brinkø, A. (Creator), Eikeland, E. Z. (Creator), Kato, A. (Creator) & Jensen, H. H. (Creator), Cambridge Crystallographic Data Centre, 2018
DOI: 10.5517/ccdc.csd.cc1zw4tt, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc1zw4tt&sid=DataCite
Dataset