Projects per year
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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変異酵素の立体構造を化学的に操作できるシャペロン化合物の合理的設計と機能解析
Kato, A. (Principal Investigator), 石井達 (Co-Investigator(Kenkyū-buntansha)), 中込泉 (Co-Investigator(Kenkyū-buntansha)) & 名取良浩 (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2024/04/01 → 2027/03/31
Project: Research Project
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Analyses of essential interactions of iminosugars with the Hex A active site and evaluation of their pharmacological chaperone effects for Tay-Sachs disease
Kato, A. (PI)
2017/04/01 → 2020/03/31
Project: Research
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Enantiomeric C-6 fluorinated swainsonine derivatives as highly selective and potent inhibitors of α-mannosidase and α-L-rhamnosidase: Design, synthesis and structure-activity relationship study
Gao, F.-T., Zhang, M., Shimadate, Y., Kato, A., Li, Y.-X., Jia, Y.-M. & Yu, C.-Y., 2025/01/01, In: European Journal of Medicinal Chemistry. 282, p. 117031Research output: Contribution to journal › Article › peer-review
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Synthesis of 8-epi-L-swainsonine, related C6 alkylated derivatives and their α-L-rhamnosidase inhibition
Shimadate, Y., Oshima, S., Kasamatsu, N., Yamamoto, S., Taguchi, A., Nash, R. J., Fleet, G. W. J., Okada, T., Toyooka, N. & Kato, A., 2024/03/01, In: Tetrahedron Letters. p. 155008Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Distinctive accumulation of globotriaosylceramide and globotriaosylsphingosine in a mouse model of classic Fabry disease
Taguchi, A., Ishii, S., Mikame, M. & Maruyama, H., 2023/03, In: Molecular Genetics and Metabolism Reports. 34, 100952.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations
Datasets
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Structure of the Clostridium perfringens GH89 in complex with alpha-HNJNAc
Zhu, S. (Contributor), Jagadeesh, Y. (Contributor), Tran, A. T. (Contributor), Imaeda, S. (Contributor), Boraston, A. (Contributor), Alonzi, D. S. (Contributor), Poveda, A. (Contributor), Zhang, Y. (Contributor), Désiré, J. (Contributor), Charollais-Thoenig, J. (Contributor), Demotz, S. (Contributor), Kato, A. (Contributor), Butters, T. D. (Contributor), Jiménez-Barbero, J. (Contributor), Sollogoub, M. (Contributor) & Blériot, Y. (Contributor), Protein Data Bank (PDB), 2021/07/28
DOI: 10.2210/pdb7MFK/pdb, https://www.wwpdb.org/pdb?id=pdb_00007mfk
Dataset
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CCDC 1015485: Experimental Crystal Structure Determination
Zhu, S. (Creator), Tran, A. T. (Creator), Hirokami, Y. (Creator), Gontard, G. (Creator), Khaled, O. (Creator), Zhang, Y. (Creator), Kato, A. (Creator), Blériot, Y. (Creator) & Sollogoub, M. (Creator), Cambridge Crystallographic Data Centre, 2019
DOI: 10.5517/ccdc.csd.cc132plg, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc132plg&sid=DataCite
Dataset
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CCDC 1023880: Experimental Crystal Structure Determination
Blériot, Y. (Creator), Auberger, N. (Creator), Jagadeesh, Y. (Creator), Gauthier, C. (Creator), Prencipe, G. (Creator), Tran, A. T. (Creator), Marrot, J. (Creator), Désiré, J. (Creator), Yamamoto, A. (Creator), Kato, A. (Creator) & Sollogoub, M. (Creator), Cambridge Crystallographic Data Centre, 2015
DOI: 10.5517/cc13cfd9, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc13cfd9&sid=DataCite
Dataset
Prizes
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Tetrahedron: Asymmetry: Top-25 Most Cited Articles 2010-2011 Award
Kato, A. (Recipient), 2012/01
Prize
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Tetrahedron: Asymmetry: Top-25 Most Cited Articles 2010-2011 Award
Kato, A. (Recipient), 2012/01
Prize
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植物由来化合物の機能性化粧品素材への応用：Ginnalin B の生物活性に関する研究
Shinzawa, K. (Speaker)
2022/10/16Activity: Talk or presentation › Oral presentation
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5-C-分岐型デオキシノジリマイシンを基盤としたGAA高親和性シャペロンのデザイン研究
Shinzawa, K. (Speaker)
2022/10/01Activity: Talk or presentation › Oral presentation
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Casuarine誘導体の各種グリコシダーゼに対する阻害活性と構造活性相関
Shinzawa, K. (Speaker)
2022/03/28Activity: Talk or presentation › Oral presentation