Why is the minimum unit of life a cell? Building an "RNA world" model protocell using droplet-based microfluidics

Shigeyoshi Matsumura*, Faith M. Coldren, Annick Marin, Ali Fallah-Araghi, Andrew D. Griffiths, Michaël Ryckelynck

*この論文の責任著者

研究成果: 書籍の章/レポート/会議録会議への寄与査読

抄録

This paper reports building an experimental model of an "RNA world" protocell using droplet-based microfluidics. The model protocell is much closer to a prebiotic form of life rather than previously reported synthetic cell models [1-3], since it does not contain a complicated cell-free protein expression system. Experimental evolution of this simple model protocell is a powerful model to investigate the role of compartmentalization in early biology. This study experimentally demonstrates that proto-cellular compartments are essential for early life-system evolution.

本文言語英語
ホスト出版物のタイトルProceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
出版社Chemical and Biological Microsystems Society
ページ166-168
ページ数3
ISBN(印刷版)9780979806452
出版ステータス出版済み - 2012
イベント16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 - Okinawa, 日本
継続期間: 2012/10/282012/11/01

出版物シリーズ

名前Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012

学会

学会16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
国/地域日本
CityOkinawa
Period2012/10/282012/11/01

ASJC Scopus 主題領域

  • 化学工学(その他)
  • バイオエンジニアリング

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