@article{d7e74c4ff7ba4c07bc38621d6bbf792b,
title = "Treatment of mediastinitis due to methicillin-resistant staphylococcus aureus in a renal dysfunction patient undergoing adjustments to the linezolid dose",
abstract = "This study is the first case report of the treatment of methicillin-resistant Staphylococcus aureus (MRSA) mediastinitis using therapeutic drug monitoring of the serum and wound exudate concentrations of linezolid in a renal dysfunction patient. In the present study, the serum trough concentration of linezolid was maintained between 2 and 7 μg/mL. Therapeutic drug monitoring dosage adjustments may be especially useful in patients with renal dysfunction and severe MRSA infection.",
keywords = "Linezolid, Mediastinitis, Methicillin-resistant Staphylococcus aureus, Renal dysfunction, Therapeutic drug monitoring",
author = "Yasuhiro Tsuji and Masato Tashiro and Nobuyuki Ashizawa and Yukio Ota and Hayato Obi and Saori Nagura and Munetoshi Narukawa and Kazuaki Fukahara and Naoki Yoshimura and Hideto To and Yoshihiro Yamamoto",
note = "Publisher Copyright: {\textcopyright} 2015 The Japanese Society of Internal Medicine. All rights reserved.",
year = "2015",
month = jan,
day = "15",
doi = "10.2169/internalmedicine.54.2292",
language = "英語",
volume = "54",
pages = "235--239",
journal = "Internal Medicine",
issn = "0918-2918",
publisher = "Japanese Society of Internal Medicine",
number = "2",
}