Synthetic study towards construction of potential scaffold of antitumor agents andrastins

Shuqiang Yin; Kenji Sugimoto; Hideo Nemoto; Yuji Matsuya

doi:10.3987/COM-16-S(S)2

Synthetic study towards construction of potential scaffold of antitumor agents andrastins

Shuqiang Yin, Kenji Sugimoto, Hideo Nemoto, Yuji Matsuya^*

^*この論文の責任著者

薬品製造学研究室

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

3 被引用数 (Scopus)

抄録

For a construction of potential scaffold of antitumor agents andrastins, intramolecular Diels-Alder reaction of the triene composed of trans-fused AB ring with tethered D ring was examined. The reaction in refluxing toluene afforded a desired cis-fused hydrindane skeleton, the relative stereochemistries of which were unambiguously determined by X-ray crystallographic analysis.

本文言語	英語
ページ（範囲）	187-199
ページ数	13
ジャーナル	Heterocycles
巻	95
号	1
DOI	https://doi.org/10.3987/COM-16-S(S)2
出版ステータス	出版済み - 2017

ASJC Scopus 主題領域

分析化学
薬理学
有機化学

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10.3987/COM-16-S(S)2

引用スタイル

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title = "Synthetic study towards construction of potential scaffold of antitumor agents andrastins",

abstract = "For a construction of potential scaffold of antitumor agents andrastins, intramolecular Diels-Alder reaction of the triene composed of trans-fused AB ring with tethered D ring was examined. The reaction in refluxing toluene afforded a desired cis-fused hydrindane skeleton, the relative stereochemistries of which were unambiguously determined by X-ray crystallographic analysis.",

author = "Shuqiang Yin and Kenji Sugimoto and Hideo Nemoto and Yuji Matsuya",

note = "Publisher Copyright: {\textcopyright}2017 The Japan Institute of Heterocyclic Chemistry.",

year = "2017",

doi = "10.3987/COM-16-S(S)2",

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AU - Yin, Shuqiang

AU - Sugimoto, Kenji

AU - Nemoto, Hideo

AU - Matsuya, Yuji

PY - 2017

Y1 - 2017

N2 - For a construction of potential scaffold of antitumor agents andrastins, intramolecular Diels-Alder reaction of the triene composed of trans-fused AB ring with tethered D ring was examined. The reaction in refluxing toluene afforded a desired cis-fused hydrindane skeleton, the relative stereochemistries of which were unambiguously determined by X-ray crystallographic analysis.

AB - For a construction of potential scaffold of antitumor agents andrastins, intramolecular Diels-Alder reaction of the triene composed of trans-fused AB ring with tethered D ring was examined. The reaction in refluxing toluene afforded a desired cis-fused hydrindane skeleton, the relative stereochemistries of which were unambiguously determined by X-ray crystallographic analysis.

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DO - 10.3987/COM-16-S(S)2

M3 - 学術論文

AN - SCOPUS:85025709492

SN - 0385-5414

VL - 95

SP - 187

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JO - Heterocycles

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Synthetic study towards construction of potential scaffold of antitumor agents andrastins

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