Successful management of refractory constipation using Kampo medicine Mashiningan in a patient with wild-type ATTR cardiac amyloidosis

Teruhiko Imamura; Masakazu Hori; Shuhei Tanaka; Koichiro Kinugawa

doi:10.1016/j.jccase.2021.06.004

Successful management of refractory constipation using Kampo medicine Mashiningan in a patient with wild-type ATTR cardiac amyloidosis

Teruhiko Imamura^*, Masakazu Hori, Shuhei Tanaka, Koichiro Kinugawa

^*この論文の責任著者

内科学（第二）講座

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

3 被引用数 (Scopus)

抄録

A wild-type ATTR amyloidosis is a systemic disease with multi-organ dysfunction, involving heart, kidney, skin, and gastrointestinal tract, due to deposition of wild-type transthyretin in each organ. We had a 76-year-old man diagnosed with wild-type ATTR cardiac amyloidosis, whose heart failure symptom improved by anti-heart failure medications but constipation refractory to multiple conventional medications persisted. Following the conversion from lubiprostone to Kampo medicine mashiningan, his average days per one evacuation decreased from around 7.0 days down to 1.6 days. Mashininigan might be an alternative option to improve refractory constipation in patients with cardiac amyloidosis. <Learning objective: Mashininigan might be an alternative option to improve refractory constipation in patients with cardiac amyloidosis.>

本文言語	英語
ページ（範囲）	34-36
ページ数	3
ジャーナル	Journal of Cardiology Cases
巻	25
号	1
DOI	https://doi.org/10.1016/j.jccase.2021.06.004
出版ステータス	出版済み - 2022/01

ASJC Scopus 主題領域

循環器および心血管医学

文献へのアクセス

10.1016/j.jccase.2021.06.004

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引用スタイル

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abstract = "A wild-type ATTR amyloidosis is a systemic disease with multi-organ dysfunction, involving heart, kidney, skin, and gastrointestinal tract, due to deposition of wild-type transthyretin in each organ. We had a 76-year-old man diagnosed with wild-type ATTR cardiac amyloidosis, whose heart failure symptom improved by anti-heart failure medications but constipation refractory to multiple conventional medications persisted. Following the conversion from lubiprostone to Kampo medicine mashiningan, his average days per one evacuation decreased from around 7.0 days down to 1.6 days. Mashininigan might be an alternative option to improve refractory constipation in patients with cardiac amyloidosis. ",

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