@inproceedings{34b66297292544eba782caddcecb7672,
title = "Label-free characterization of degenerative changes in articular cartilage by Raman spectroscopy",
abstract = "Osteoarthritis (OA) is very common joint disease in the aging population. Main symptom of OA is accompanied by degenerative changes of articular cartilage. Raman spectroscopy is a label-free technique which enables to analyze molecular composition in degenerative cartilage. We generated an animal OA model surgically induced by knee joint instability and performed Raman spectroscopic analysis for the articular cartilage. In the result, Raman spectral data of the articular cartilage showed drastic changes in comparison between OA and control side. The relative intensity of phosphate band increases in the degenerative cartilage.",
keywords = "Articular cartilage, Cartilage matrix, Osteoarthritis, Raman spectroscopy, Type II collagen",
author = "Yusuke Oshima and Mayu Akehi and Hiroshi Kiyomatsu and Hiromasa Miura",
note = "Publisher Copyright: {\textcopyright} 2017 SPIE.; 3rd Biomedical Imaging and Sensing Conference ; Conference date: 19-04-2017 Through 21-04-2017",
year = "2017",
doi = "10.1117/12.2275047",
language = "英語",
series = "Proceedings of SPIE - The International Society for Optical Engineering",
publisher = "SPIE",
editor = "Yasuhiro Awatsuji and Osamu Matoba and Yoshihisa Aizu and Toyohiko Yatagai",
booktitle = "Biomedical Imaging and Sensing Conference",
}