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GSK-3β/CREB axis mediates IGF-1-induced ECM/adhesion molecule expression, cell cycle progression and monolayer permeability in retinal capillary endothelial cells: Implications for diabetic retinopathy
Takhellambam S. Devi, Lalit P. Singh
*
,
Ken Ichi Hosoya
, Tetsuya Terasaki
*
この論文の責任著者
薬剤学研究室
研究成果
:
ジャーナルへの寄稿
›
学術論文
›
査読
26
被引用数 (Scopus)
概要
フィンガープリント
フィンガープリント
「GSK-3β/CREB axis mediates IGF-1-induced ECM/adhesion molecule expression, cell cycle progression and monolayer permeability in retinal capillary endothelial cells: Implications for diabetic retinopathy」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。
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Keyphrases
Growth Factors
100%
Diabetic Retinopathy
100%
Insulin-like
100%
Cell Cycle Progression
100%
Retinal Capillary Endothelial Cells
100%
Adhesion Molecules Expression
100%
Glycogen Synthase kinase-3β (GSK-3β)
100%
Monolayer Permeability
100%
Fibronectin
33%
TR-iBRB2 Cells
33%
VE-cadherin
33%
Phosphorylation
22%
Endothelial Dysfunction
22%
Blood-retinal Barrier
22%
Cyclin D1 (CCND1)
22%
Adhesion Molecules
11%
Molecular Mechanism
11%
Gene Expression
11%
ECM Proteins
11%
Glycogen Synthase Kinase 3 (GSK3)
11%
Dominant Negative
11%
Early Diabetic Retinopathy
11%
Cell Cycle Regulation
11%
Cellular Mechanisms
11%
Retinal Endothelial Cells
11%
Endothelial Cell Line
11%
Enhanced Expression
11%
FITC-dextran
11%
Membrane Permeability
11%
Stable Transfection
11%
Barrier Breakdown
11%
CREB Transcription Factor
11%
Progression Factor
11%
Kinase Function
11%
Neuroscience
Diabetic Retinopathy
100%
CREB
100%
Cell Cycle Progression
100%
Insulin-Like Growth Factor 1
100%
Cell Adhesion Proteins
100%
Glycogen Synthase Kinase 3beta
100%
Fibronectin
37%
Vascular Endothelial Cadherin
37%
Blood Retina Barrier
25%
Cyclin D1
25%
Cyclic Adenosine Monophosphate
12%
Kinase
12%
Transcription Factors
12%
Gene Expression
12%
Cell Line
12%
Growth Factor
12%
Stable Transfection
12%
Cell Cycle Regulation
12%
Dextran
12%
Membrane Permeability
12%
Biochemistry, Genetics and Molecular Biology
Insulin-Like Growth Factor 1
100%
Cell Cycle Progression
100%
CREB
100%
Glycogen Synthase Kinase
100%
Cell Adhesion Proteins
100%
VE-cadherin
37%
Fibronectin
37%
Blood Retina Barrier
25%
Cyclin D1
25%
Upregulation
12%
Transcription Factors
12%
Growth Factor
12%
Cytokine
12%
Gene Expression
12%
Cyclic Adenosine Monophosphate
12%
Downregulation
12%
Kinase
12%
Phosphotransferase
12%
Cell Cycle Regulation
12%
Membrane Permeability
12%
Dextran
12%
Stable Transfection
12%
Immunology and Microbiology
Cell Cycle Progression
100%
Somatomedin C
100%
Capillary Endothelial Cell
100%
Cell Adhesion Proteins
100%
VE-cadherin
37%
Fibronectin
37%
Blood Retina Barrier
25%
Cyclin D1
25%
Upregulation
12%
Cytokine
12%
Gene Expression
12%
Downregulation
12%
Transcription Factors
12%
Growth Factor
12%
Endothelial Cell Line
12%
Membrane Permeability
12%
Stable Transfection
12%
Cell Cycle Regulation
12%
Pharmacology, Toxicology and Pharmaceutical Science
Diabetic Retinopathy
100%
Somatomedin C
100%
Glycogen Synthase Kinase 3beta
100%
Cell Adhesion Proteins
100%
Fibronectin
37%
Vascular Endothelial Cadherin
37%
Endothelial Dysfunction
25%
Cyclin D1
25%
Transcription Factors
12%
Phosphotransferase
12%
Cytokine
12%
Growth Factor
12%
Fluorescein Isothiocyanate Dextran
12%