Gomisin N enhances TRAIL-induced apoptosis via reactive oxygen species-mediated up-regulation of death receptors 4 and 5

Keyphrases

• Reactive Oxygen Species 100%
• TRAIL-induced Apoptosis 100%
• Gomisin N 100%
• Death Receptor 4 100%
• Death Receptor 5 100%
• Apoptosis 25%
• Reactive Oxygen Species Production 25%
• Cancer Therapy 12%
• In Cancer 12%
• Molecular Mechanism 12%
• Antioxidant 12%
• Pharmacological Studies 12%
• Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) 12%
• Anti-inflammatory Activity 12%
• Antioxidant System 12%
• Anticancer 12%
• TRAIL Receptors 12%
• Caspase-8 12%
• Caspase-3 12%
• Lignans 12%
• N-acetylcysteine 12%
• Pan-caspase Inhibitor 12%
• Tumor Necrosis Factor Superfamily 12%
• PARP Inhibitor (PARPi) 12%
• Schisandra chinensis 12%
• Apoptosis Markers 12%
• Antihepatotoxic 12%
• Caspase Cascade 12%

Pharmacology, Toxicology and Pharmaceutical Science

• Reactive Oxygen Metabolite 100%
• Gomisin 100%
• Death Receptor 4 100%
• Death Receptor 5 100%
• Antioxidant 25%
• Malignant Neoplasm 12%
• Tumor Necrosis Factor 12%
• Tumor Necrosis Factor Related Apoptosis Inducing Ligand 12%
• Anti-Inflammatory Drug 12%
• Caspase 12%
• Caspase 3 12%
• Lignan 12%
• Acetylcysteine 12%
• Hepatotoxicity 12%
• Tumor Necrosis Factor Related Apoptosis Inducing Ligand Receptor 12%
• Caspase Inhibitor 12%
• Schisandra chinensis 12%
• Caspase 8 12%

Neuroscience

• Reactive Oxygen Species 100%
• Death Receptor 5 100%
• Death Receptor 4 100%
• Gomisin 100%
• Caspase 25%
• Necrosis 12%
• Anti-Inflammatory 12%
• Antioxidant 12%
• Caspase 8 12%
• Tumor Necrosis Factor Related Apoptosis Inducing Ligand 12%
• Tumor Necrosis Factor Related Apoptosis Inducing Ligand Receptor 12%
• Caspase 3 12%
• Acetylcysteine 12%
• Lignan 12%
• Poly ADP Ribose Polymerase 12%