Exploring the therapeutic potential of 4,4′-dimethoxychalcone: Inducing apoptosis in cancer cells via ER stress and autophagy disruption

Pharmacology, Toxicology and Pharmaceutical Science

• Malignant Neoplasm 100%
• Flavonoid 100%
• Mitogen Activated Protein Kinase 50%
• Antiapoptotic 50%
• Anticarcinogen 50%
• Reactive Oxygen Metabolite 50%
• Activating Transcription Factor 4 50%
• Chloroquine 50%
• Biological Activity 50%
• Caspase 3 50%
• Drug Discovery 50%
• Caspase Inhibitor 50%
• Protein Bcl 2 50%
• Rapamycin 50%
• Cathepsin D 50%
• 3 Methyladenine 50%
• Protein Bax 50%
• Growth Arrest and DNA Damage Inducible Protein 153 50%

Keyphrases

• 4,4′-dimethoxychalcone 100%
• Autophagosome Accumulation 10%

Biochemistry, Genetics and Molecular Biology

• ATF4 20%