@article{77943ea20af14bb0b0664b734c546afb,
title = "Efficient synthesis of (R)- and (S)-1-amino-2,2-difluorocyclopropanecarboxylic acid via lipase-catalyzed desymmetrization of prochiral precursors",
abstract = "The asymmetric syntheses of (+)-(R)-1-amino-2,2-difluorocyclopropane-1-carboxylic acid and its enantiomer have been accomplished. Key reactions in the synthetic design are lipase-catalyzed desymmetrization of a prochiral diol and a prochiral diacetate.",
author = "Masayuki Kirihara and Masashi Kawasaki and Tomofumi Takuwa and Hiroko Kakuda and Takahiro Wakikawa and Yoshio Takeuchi and Kirk, {Kenneth L.}",
year = "2003",
month = jun,
day = "20",
doi = "10.1016/S0957-4166(03)00350-1",
language = "英語",
volume = "14",
pages = "1753--1761",
journal = "Tetrahedron Asymmetry",
issn = "0957-4166",
publisher = "Elsevier Ltd.",
number = "12",
}