抄録
Neurodegenerative diseases commonly induce irreversible destruction of central nervous system (CNS) neuronal networks, resulting in permanent functional impairments. Effective medications against neurodegenerative diseases are currently lacking. Ashwagandha (roots of Withania somnifera DUNAL) is used in traditional Indian medicine (Ayurveda) for general debility, consumption, nervous exhaustion, insomnia, and loss of memory. In this review, we summarize various effects and mechanisms of Ashwagandha extracts and related compounds on in vitro and in vivo models of neurodegenerative diseases such as Alzheimer's disease and spinal cord injury.
| 本文言語 | 英語 |
|---|---|
| ページ（範囲） | 892-897 |
| ページ数 | 6 |
| ジャーナル | Biological and Pharmaceutical Bulletin |
| 巻 | 37 |
| 号 | 6 |
| DOI | |
| 出版ステータス | 出版済み - 2014/06 |
ASJC Scopus 主題領域
- 薬理学
- 薬科学