Does the structure of transthyretin amyloid fibrils vary depending on the organ of accumulation?

Mineyuki Mizuguchi

doi:10.1016/j.str.2024.11.002

Does the structure of transthyretin amyloid fibrils vary depending on the organ of accumulation?

Mineyuki Mizuguchi^*

^*この論文の責任著者

構造生物学研究室

研究成果: ジャーナルへの寄稿 › コメント/討論

抄録

In this issue of Structure, Nguyen et al.¹ reveal that amyloid fibrils of the transthyretin (TTR) V30M variant from the heart and nerves of the same patient exhibit structural homogeneity. This finding is crucial for advancing our understanding of V30M-TTR amyloid deposition, which leads to fatal ATTRv amyloidosis.

本文言語	英語
ページ（範囲）	2181-2182
ページ数	2
ジャーナル	Structure
巻	32
号	12
DOI	https://doi.org/10.1016/j.str.2024.11.002
出版ステータス	出版済み - 2024/12/05

ASJC Scopus 主題領域

構造生物学
分子生物学

文献へのアクセス

10.1016/j.str.2024.11.002

引用スタイル

@article{51d1c8333dc94d538071fb50f16f6c1c,

title = "Does the structure of transthyretin amyloid fibrils vary depending on the organ of accumulation?",

abstract = "In this issue of Structure, Nguyen et al.1 reveal that amyloid fibrils of the transthyretin (TTR) V30M variant from the heart and nerves of the same patient exhibit structural homogeneity. This finding is crucial for advancing our understanding of V30M-TTR amyloid deposition, which leads to fatal ATTRv amyloidosis.",

author = "Mineyuki Mizuguchi",

note = "Publisher Copyright: {\textcopyright} 2024 Elsevier Inc.",

year = "2024",

month = dec,

day = "5",

doi = "10.1016/j.str.2024.11.002",

language = "英語",

volume = "32",

pages = "2181--2182",

journal = "Structure",

issn = "0969-2126",