Choto-san, a Kampo formula, improves chronic cerebral hypoperfusion-induced spatial learning deficit via stimulation of muscarinic M₁ receptor

Keyphrases

• Kampo Formula 100%
• Learning Impairment 100%
• Spatial Learning 100%
• Muscarinic Receptors 100%
• Chronic Cerebral Hypoperfusion 100%
• Uncaria 100%
• Assertiveness 37%
• Acetylcholine 25%
• Mechanism of Action 12%
• Japan 12%
• Beneficial Effects 12%
• Therapeutic Effect 12%
• Sham 12%
• Cognitive Impairment 12%
• Traditional Medicine 12%
• Permanent Occlusion 12%
• Vascular Dementia 12%
• Major Constituents 12%
• Cognitive Dysfunction 12%
• Kampo 12%
• Neuronal Mechanisms 12%
• Common Carotid Artery 12%
• Pirenzepine 12%
• M1 Antagonist 12%
• Chronic Hypoperfusion 12%
• Placebo-controlled Study 12%
• Reduced Rate 12%
• Induced Learning 12%
• Spatial Memory Deficit 12%
• Dominance Tests 12%

Pharmacology, Toxicology and Pharmaceutical Science

• Kampo Medicine (Drug) 100%
• Learning Disorder 100%
• Muscarinic M1 Receptor 100%
• Uncaria 100%
• Acetylcholine 25%
• Cognitive Defect 25%
• Therapeutic Effect 12%
• Multiinfarct Dementia 12%
• Amnesia 12%
• Pirenzepine 12%
• Placebo-Controlled Study 12%
• Muscarinic M1 Receptor Antagonist 12%