TY - JOUR
T1 - Chiral Sensing Using Circularly Polarized Luminescence of Bis(phenanthroline dicarboxylic acid) Eu III Complex Induced by Allosteric-type Interaction with Amino Acid Molecules
AU - Iwamura, Munetaka
AU - Fujii, Mai
AU - Yamada, Ayano
AU - Koike, Hikaru
AU - Nozaki, Koichi
N1 - Publisher Copyright:
© 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
PY - 2019/2/15
Y1 - 2019/2/15
N2 - [Eu(pda) 2 ] − and [Eu(bda) 2 ] − (pda=1,10-phenanthroline-2, 9-dicarboxylic acid; bda=2,2′ bipyridine 5,5′-dicarboxylic acid) have an achiral D 2d structure in crystals. These complexes exhibit circularly polarized luminescence (CPL) in water containing chiral amino acids. In this work, induced CPL of [Eu(pda) 2 ] − and [Eu(bda) 2 ] − in water solutions containing a mixture of d- and l- amino acids were examined. Plots of g lum values of the induced CPL as a function of mol-fraction of l- and d- arginine reveal that [Eu(pda) 2 ] − favors homo-association ([Eu(pda) 2 ] − -(l-arginine) 2 or [Eu(pda) 2 ] − -(d-arginine) 2 ) over hetero-association {[Eu(pda) 2 ] − -(l-arginine)⋅(d-arginine)}. This suggests that association of an arginine molecule induces a structural change in [Eu(pda) 2 ] − to promote chiral selective association to another arginine, i.e., homo-allosteric association. On the other hand, the system of [Eu(pda) 2 ] − with histidine favors hetero-allosteric association over homo-association. No allosteric effect is recognized in CPL from [Eu(bda) 2 ] − .
AB - [Eu(pda) 2 ] − and [Eu(bda) 2 ] − (pda=1,10-phenanthroline-2, 9-dicarboxylic acid; bda=2,2′ bipyridine 5,5′-dicarboxylic acid) have an achiral D 2d structure in crystals. These complexes exhibit circularly polarized luminescence (CPL) in water containing chiral amino acids. In this work, induced CPL of [Eu(pda) 2 ] − and [Eu(bda) 2 ] − in water solutions containing a mixture of d- and l- amino acids were examined. Plots of g lum values of the induced CPL as a function of mol-fraction of l- and d- arginine reveal that [Eu(pda) 2 ] − favors homo-association ([Eu(pda) 2 ] − -(l-arginine) 2 or [Eu(pda) 2 ] − -(d-arginine) 2 ) over hetero-association {[Eu(pda) 2 ] − -(l-arginine)⋅(d-arginine)}. This suggests that association of an arginine molecule induces a structural change in [Eu(pda) 2 ] − to promote chiral selective association to another arginine, i.e., homo-allosteric association. On the other hand, the system of [Eu(pda) 2 ] − with histidine favors hetero-allosteric association over homo-association. No allosteric effect is recognized in CPL from [Eu(bda) 2 ] − .
KW - allosteric effect
KW - amino acids
KW - chiral sensing
KW - circularly polarized luminescence
KW - lanthanide complexes
UR - http://www.scopus.com/inward/record.url?scp=85060586022&partnerID=8YFLogxK
U2 - 10.1002/asia.201801777
DO - 10.1002/asia.201801777
M3 - 学術論文
C2 - 30600941
AN - SCOPUS:85060586022
SN - 1861-4728
VL - 14
SP - 561
EP - 567
JO - Chemistry - An Asian Journal
JF - Chemistry - An Asian Journal
IS - 4
ER -