Chiisanoside is not absorbed but inhibits oil absorption in the small intestine of rodents

Kazuma Yoshizumi; Kaeko Murota; Shiro Watanabe; Hironori Tomi; Tomoko Tsuji; Junji Terao

doi:10.1271/bbb.70761

Chiisanoside is not absorbed but inhibits oil absorption in the small intestine of rodents

Kazuma Yoshizumi, Kaeko Murota, Shiro Watanabe, Hironori Tomi, Tomoko Tsuji, Junji Terao^*

^*この論文の責任著者

和漢医薬学総合研究所研究開発部門病態制御分野（生体防御学領域）

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

21 被引用数 (Scopus)

抄録

Chiisanoside is the main component of Acanthopanax sessiliflorus leaves. Simultaneous administration of chiisanoside resulted in a decrease in the plasma TG level and increase of undigested TG in the intestinal lumen after oil gavage to mice. This suggests that chiisanoside has the potential to prevent obesity as a lipase inhibitor which suppresses fat absorption in vivo.

本文言語	英語
ページ（範囲）	1126-1129
ページ数	4
ジャーナル	Bioscience, biotechnology, and biochemistry
巻	72
号	4
DOI	https://doi.org/10.1271/bbb.70761
出版ステータス	出版済み - 2008

ASJC Scopus 主題領域

バイオテクノロジー
分析化学
生化学
応用微生物学とバイオテクノロジー
分子生物学
有機化学

UN SDG

この成果は、次の持続可能な開発目標に貢献しています

文献へのアクセス

10.1271/bbb.70761

引用スタイル

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title = "Chiisanoside is not absorbed but inhibits oil absorption in the small intestine of rodents",

abstract = "Chiisanoside is the main component of Acanthopanax sessiliflorus leaves. Simultaneous administration of chiisanoside resulted in a decrease in the plasma TG level and increase of undigested TG in the intestinal lumen after oil gavage to mice. This suggests that chiisanoside has the potential to prevent obesity as a lipase inhibitor which suppresses fat absorption in vivo.",

keywords = "3, 4-seco-lupane triterpenoid saponin, Acanthopanax sessiliflorus, Chiisanoside, Intestinal absorption, Lipase inhibitor",

author = "Kazuma Yoshizumi and Kaeko Murota and Shiro Watanabe and Hironori Tomi and Tomoko Tsuji and Junji Terao",

year = "2008",

doi = "10.1271/bbb.70761",

language = "英語",

volume = "72",

pages = "1126--1129",

journal = "Bioscience, biotechnology, and biochemistry",

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AU - Yoshizumi, Kazuma

AU - Murota, Kaeko

AU - Watanabe, Shiro

AU - Tomi, Hironori

AU - Tsuji, Tomoko

AU - Terao, Junji

PY - 2008

Y1 - 2008

N2 - Chiisanoside is the main component of Acanthopanax sessiliflorus leaves. Simultaneous administration of chiisanoside resulted in a decrease in the plasma TG level and increase of undigested TG in the intestinal lumen after oil gavage to mice. This suggests that chiisanoside has the potential to prevent obesity as a lipase inhibitor which suppresses fat absorption in vivo.

AB - Chiisanoside is the main component of Acanthopanax sessiliflorus leaves. Simultaneous administration of chiisanoside resulted in a decrease in the plasma TG level and increase of undigested TG in the intestinal lumen after oil gavage to mice. This suggests that chiisanoside has the potential to prevent obesity as a lipase inhibitor which suppresses fat absorption in vivo.

KW - 3, 4-seco-lupane triterpenoid saponin

KW - Acanthopanax sessiliflorus

KW - Chiisanoside

KW - Intestinal absorption

KW - Lipase inhibitor

UR - http://www.scopus.com/inward/record.url?scp=43549101667&partnerID=8YFLogxK

U2 - 10.1271/bbb.70761

DO - 10.1271/bbb.70761

M3 - 学術論文

C2 - 18391464

AN - SCOPUS:43549101667

SN - 0916-8451

VL - 72

SP - 1126

EP - 1129

JO - Bioscience, biotechnology, and biochemistry

JF - Bioscience, biotechnology, and biochemistry

IS - 4

ER -

Chiisanoside is not absorbed but inhibits oil absorption in the small intestine of rodents

抄録

ASJC Scopus 主題領域

UN SDG

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